XELODA Ressources

Application Information

This drug has been submitted to the FDA under the reference 020896/001.

Names and composition

"XELODA" is the commercial name of a drug composed of CAPECITABINE.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
020896/001 XELODA CAPECITABINE TABLET/ORAL 150MG
020896/002 XELODA CAPECITABINE TABLET/ORAL 500MG

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
090943/001 CAPECITABINE CAPECITABINE TABLET/ORAL 150MG
090943/002 CAPECITABINE CAPECITABINE TABLET/ORAL 500MG
091649/001 CAPECITABINE CAPECITABINE TABLET/ORAL 150MG
091649/002 CAPECITABINE CAPECITABINE TABLET/ORAL 500MG
200483/001 CAPECITABINE CAPECITABINE TABLET/ORAL 150MG
200483/002 CAPECITABINE CAPECITABINE TABLET/ORAL 500MG
202593/001 CAPECITABINE CAPECITABINE TABLET/ORAL 150MG
202593/002 CAPECITABINE CAPECITABINE TABLET/ORAL 500MG
204741/001 CAPECITABINE CAPECITABINE TABLET/ORAL 150MG
204741/002 CAPECITABINE CAPECITABINE TABLET/ORAL 500MG
207456/001 CAPECITABINE CAPECITABINE TABLET/ORAL 150MG
207456/002 CAPECITABINE CAPECITABINE TABLET/ORAL 500MG
020896/001 XELODA CAPECITABINE TABLET/ORAL 150MG
020896/002 XELODA CAPECITABINE TABLET/ORAL 500MG

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A licensed doctor will try to answer your question as quickly as possible.

Answered questions

How long Xeloda stays in the body after 6 months taking 7 pills daily?
Asked by Latoria Kroetz 2 months ago.

Xeloda (capecitabine) is metabolized and excreted before the day is over that you took it. Elimination half-life is < 1 hour, meaning within ~4 hours virtually all of it is gone. Now, the effects of Xeloda can last for weeks sometimes, long after the last molecule of the drug has gone. Think about getting a sunburn... long after you have left the sun, the effects (sunburn, pain) persist long after you have ceased sun worshipping. God bless, best wishes Answered by Carolyne Wenke 2 months ago.

I'm not sure, but I was taking 8 pills a day for 6 months until a couple of weeks ago, and I'm still experiencing one of the side effects - dry skin, soreness on hands and feet. I have asked my nurse about side effects, and she said it takes some time for your body to go back to normal. Answered by Makeda Machen 2 months ago.


What can anyone tell me about Xeloda?
I've been fighting liver cancer for almost 3 years now. I had colon-rectal cancer, but that was taken care of through surgery. Just had a 2 year check up and I'm still clean. But, now we're trying Xeloda for my liver. What can I expect, and what side efeects? Asked by Bethany Berardi 2 months ago.

Xeloda, or capecitabine, is an oral form of the chemotherapy known as 5-fluorouracil (5FU). It is a nucleoside analog and works in many types of cancers, but most commonly in gastrointestinal cancers such as colorectal carcinomas. The main sides effects include lowering of blood counts and rash known as "hand-foot syndrome", but it has the potential for many other side effects seen in other chemotherapies: nausea, diarrhea, fatigue, etc. Answered by Karey Kuchar 2 months ago.

I can't answer your question, but I can pray for you. And I shall. I wish you well. Answered by Brian Mosha 2 months ago.


Has anyone been prescribed Xeloda for metastatic breast cancer?
to the Madator, the reason why I include the year 1997 was because I had never needed any medications, that everything started after my work injury. My blood sugars went up after my first bout with cancer. still suffer with dystonia from the RSD and over the last 3 days it has gone completely out of control and my... Asked by Felisa Lasseigne 2 months ago.

I was diagnosed with metastatic breast cancer in 2002, it was invasive ductal carcinoma stage 3, one lymph node was positive. I had lumpectomy, chemotherapy and radiation. I took tamoxifen for 5 years. I was then put on Femera. I changed oncologists who ordered a bone scan in 2008 but failed to look at the scan. I had a MRI of my spine done because of increases in pain, incontinence and an abnormal emg test. I had a severe work injury in which I tore my left rotator cuff damaged my right shoulder, avulsed my spinal nerves and developed reflex sympathetic dystrophy and bursitis of both hips, myofascial pain of my neck back legs.The cancer has now metastasized to my liver. I threw a pulmonary embolus . The pain was managed quite well on my current medications. I was receiving Abraxane and Pamidronate until I had a serious side effect to Abraxane. I have been taking Xeloda for 9 days and I have so much pain, more than I have ever had. I have taken 160 mgs of Oxycontin and 8 Percocet just to get up. I have put a call out for my oncologist. I am just asking is this normal? I'm not taking my morning dose. She started me on 2000 mg. twice day. Matador 89 I would greatly appreciate your medical opinion. I am a RN. Medications: I had never used my drug plan until 1997 so here I go Gabapentin 1500 mg BID for pain Lipidil 160 mg OD Zofran Flexaril Ditropan Effexor Clonidine Ramapril Glyburide Metformin Prandase Percocet Oxycontin Omeprazole Hydroclorathiazide Heparin 20,000 units Xeloda Pamindronate All answers thank you so much for taking the time to answer my question Answered by Tasia Roedel 2 months ago.

to the Madator, the reason why I include the year 1997 was because I had never needed any medications, that everything started after my work injury. My blood sugars went up after my first bout with cancer. still suffer with dystonia from the RSD and over the last 3 days it has gone completely out of control and my pain has increased sooo badly that this morning I took a total of 160 mg of oxycontin and 8 percocet. I was fortunate that my oncologist did call me back. She refers to my RSD as that " wonky" disorder. She is wonderful and agreed with me increasing my pain medication to take the Xeloda. She told me that she feels the Xeloda is working and will increase my pain medication.My 2 week cycle is over this Friday and on that day I will drink an alcoholic beverage. Answered by Noriko Rothrock 2 months ago.

to the Madator, the reason why I include the year 1997 was because I had never needed any medications, that everything started after my work injury. My blood sugars went up after my first bout with cancer. still suffer with dystonia from the RSD and over the last 3 days it has gone completely out of control and my pain has increased sooo badly that this morning I took a total of 160 mg of oxycontin and 8 percocet. I was fortunate that my oncologist did call me back. She refers to my RSD as that " wonky" disorder. She is wonderful and agreed with me increasing my pain medication to take the Xeloda. She told me that she feels the Xeloda is working and will increase my pain medication.My 2 week cycle is over this Friday and on that day I will drink an alcoholic beverage. Answered by Jesus Kleyman 2 months ago.

Donna B, Briefly, YES! I shall try to explain. XELODA is usually taken together with another medicine called docetaxel for metastatic breast cancer - mBC - that has not improved after treatment with other medicines. These medicines include paclitaxel (taxol; onxol), which is classified as an antimicrotubule agent; it stops the growth of the tumour by inhibiting cell division // During mitosis, the cell uses structures called micotubules to move around the chromosomes; [in the 1990s, members of a family of drugs called the taxanes – which include docetaxel (Taxotere) and paclitaxel (Taxol) - were shown to be effective in the first-line treatment of advanced breast cancer as well as in the treatment of women who had developed resistance to the anthracyclines.] // and anthracycline-containing medicine such as doxorubicin. There is some controversy with regard to anthracycline. Studies have shown that there is only a small subpopulation of women who incrementally benefit from anthracyclines over non-anthracyclines in breast cancer. However you should be guided by your oncologist/specialist(s). I am not sure of your meaning when you state that you never used your drug plan until 1997. As you do not indicate why you had a drug plan before the date which you give for your mBC diagnosis, I must assume that your ‘severe work injury’ occurred previously to that date, and may be part of the reason, but this would not indicate why you had some diabetic meds on the list. (Unless of course, you have induced diabetes due to the cancer’s effects). Obviously anti depressants are understandable, given the circumstances. High BP can be a result of disease and medications. The omeprazole is likely for the “poly-pharmacy” and the protection of your stomach lining due to their combined effects. I have outlined, in brief, the uses for those meds on your list – about which I feel sure that as an RN, you are already aware! However, I am not sure if you are able to check adverse drug reactions. Utilising all those on your list, I note that there are some serious adverse reactions between some of those drugs. This you need to check with your prescribing doctor(s) and your pharmacist. I could list them here, but I am sure that, being quite extensive, space would not permit their inclusion. Gabapentin 1500 mg BID for pain = usually for epilepsy, diabetic neuropathy, postherpetic neuralgia, etc. Lipidil 160 mg OD= lipid level modifying. Zofran = prevents nausea and vomiting caused by surgery or cancer medicines. Flexaril = is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain. Ditropan = an anticholinergic medication used to relieve urinary and bladder difficulties. Effexor = is an antidepressant of the serotonin-norepinephrine reuptake inhibitor. Clonidine = used to treat high blood pressure, ADHD and anxiety/panic disorder. Ramapril = ACE (angiotensin-converting enzyme) inhibitor used for High BP, heart failure and prevention of heart attack and stroke. Glyburide = is used to treat type 2 diabetes. Metformin = is an oral antidiabetic drug. Prandase = is used in non insulin dependant diabetes to lower blood glucose levels. Percocet = is used to relieve moderate to severe pain. Oxycontin = is a narcotic pain reliever used to treat moderate to severe pain. Omeprazole = is a proton pump inhibitor. Hydroclorathiazide = for fluid retention in people with congestive heart failure, cirrhosis of the liver, or kidney disorders. Heparin = for preventing blood clots in the veins, arteries, or lungs. Xeloda = for metastatic breast and colorectal cancers. Pamindronate = used to prevent osteoporosis, and which may also be used when cancer has spread to the bone. As your last “Additional Details” specify this, that is why it is on your list. I wish you well. ALL ANSWERS SHOULD BE THOROUGHLY RESEARCHED, IN ANY FORUM AND ESPECIALLY IN THIS ONE. - MANY ANSWERS ARE FLAWED. It is extremely important to obtain an accurate diagnosis before trying to find a cure. Many diseases and conditions share common symptoms. The information provided here should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Hope this helps matador 89 Answered by Pearle Dehner 2 months ago.

This Site Might Help You. RE: Has anyone been prescribed Xeloda for metastatic breast cancer? I was diagnosed with metastatic breast cancer in 2002, it was invasive ductal carcinoma stage 3, one lymph node was positive. I had lumpectomy, chemotherapy and radiation. I took tamoxifen for 5 years. I was then put on Femera. I changed oncologists who ordered a bone scan in 2008 but failed to... Answered by Joseph Gottfried 2 months ago.

Well it is really hard to tell what the doctor may have been talking about from your question, but there are pills for metastatic BC and there are injections for osteoporosis (weak bones) so it is certainly possible that your mother might be having both of those especially if her cancer has metastasized to the bones. It is also possible that the doctor told her that her metastatic BC might lead to her death in the future, particularly if she asked about possible outcomes. There really isn't a usual time, some people live with metastatic BC for years, sometimes the treatments reduce metastases and sometimes the cancer spreads to other organs. There is no time-line. Answered by Suellen Westerholm 2 months ago.


Any advice on what you can take or eat to stop xeloda from making you feel sick?
hi my mum has had stage 4 colon cancer. after her op she was offered chemo which she is having and also taking xeloda (capecitabine) tablets for 14 days 11 of these day she constantly feels sick. Asked by Vanetta Bogatay 2 months ago.

Hello I took xeloda tablets for 2 out of 3 weeks for 6 months. I often had a problem with swallowing it, and that is what would make me feel sick. If I drank it with water, I would gag and feel horrible. So I tried swallowing it with milk, tea and fruit juices to help get rid of the taste when swallowing, and that really helped. Fatty foods would also make me feel nauseous so I avoided them. As English as it does sound, a cup of tea would really help me with it. I was also on oxaliplatin, and that made me feel worse than the xeloda. What else is she on, or is it just the xeloda? Feel free to message me for any other advice I may be able to give you. Answered by Augustine Yonek 2 months ago.

Pre-medication with a nausea medication, such as prochlorperazine (compazine) or ondansetron (zofran) might help. Other options: metoclopramide (reglan); patient today reported eating honeydew melon helped (I looked it up and sure enough there are folk remedy reports about these melons for nausea- interesting); others say buttermilk helps; also could try an alternate schedule of capecitabine, taking it a week on, then week off- might be easier. Talk with her doctor about all of this please as there are many options to make it more tolerable. Blessings Answered by Daphine Bordenkircher 2 months ago.

I'm sorry to hear about your mum's illness..peppermint tea is very soothing to the stomach. I also have found that coke with lots of ice and a bit of water added helps to soothe as well. Peppermint gum is another idea if she doesn't want to drink anything. Web m.d has a lot of helpful tips for illnesses and meds. Good luck to you both. I hope she feels better soon. Answered by Herman Coyco 2 months ago.


What can i use instead of Xeloda?
Asked by Janey Koo 2 months ago.

Are you experiencing side effects from Xeloda, like hand-foot syndrome? Numbness, tingling, rash? Don't ask us, ask your doctor. S/he knows what's best, and there are different options other than Xeloda. Many, many patients experience side effects with it. You're not the first and they will know what else to try you on. Answered by Clelia Shellgren 2 months ago.

Can you give additional information about why you want something different? I myself was on Xeloda (3800 mg per day). I got hand-foot syndrome, but just made sure I followed all the directions and information that my doctor gave me on how to handle it. It is not fun I know. Additionally, while you are on it, make sure you only drink un-refrigerated bottled water. Tap water IS NOT room temperature water. You can also put tap water in a glass and wait 30-minutes to an hour before you drink it. I also had to take medicine (I forgot the name) where I placed a pill on my tongue that helped to handle nausea. Are you on radiation at the same time? For me, I was on 28 days of radiation and 28 days of Xeloda. Then after that, I had surgery, and then went on infusion chemotherapy of 5FU, Leucovourin and Oxiliplatin. Xeloda is really a good chemotherapy drug, but talk with your Oncoligist if you have additional concerns. Answered by Mandi Eliassen 2 months ago.

Considering it's chemo, I would take what the oncologist suggests. Don't mess around with your health. Answered by Laine Aldworth 2 months ago.


Shuld xeloda be given if of have a bad genes?
is xeloda a danger to a person who has a bad gene Asked by Leandro Risewick 2 months ago.

xeloda is a danger to people who want to hold on to their money :))) Answered by Elena Gusa 2 months ago.

no. should is spelled like this, bad genes or not. :)))) Answered by Mercedez Patajo 2 months ago.


XELODA for breast cancer?
Has anyone on here taken xeloda for metastatic breast cancer? I was wondering how well it works and what the side effects are. Asked by Gillian Boardman 2 months ago.

I also had Xeloda for colon cancer, and the symptoms I experienced were diahorrea, sore and dry hands and feet, and darkening of the skin on my hands and feet. Answered by Tijuana Weir 2 months ago.

We had a member of our local support group who used Xeloda for two years. It did not reduce her cancer tumor's size, But her cancer did not grow or spread during those same two years. She did experience dry hands and feet and a little neuropathy. Answered by Terresa Gocha 2 months ago.

Xeloda is also used for colon cancer. My husband had it for that. Side effects according to the data are similar to other chemo drugs..infections, nausea etc. ,plus sensitivity to sunlight. Take extra care with sunblock. Hubby had minimal side effects and found it easy to take (set a reminder on your phone!). Nausea with XELODA was less than with IV 5FU, perhaps the lower daily dose is easier to handle. Unfortunately he turned out to be allergic to it (rash on back)....had to go back to IV chemo. Good luck with your treatment. Answered by Walker Figlioli 2 months ago.

If you have cancer, try taking turmeric extract also. Answered by Renata Kirkbride 2 months ago.


Are avastin and xeloda the same?
cancer medications Asked by Mario Avellar 2 months ago.

Bevacizumab (Avastin) is an antiangiogenic drug which blocks vascular endothelial growth factor A (VEGF-A) and slows the vascular growth of tumors. Capecitabine (Xeloda) is a chemotherapy pill which inhibits DNA synthisis to slow tumor growth. So while they both have the same objective to slow metastatic growth, no, they are not the same. Answered by Iesha Monagle 2 months ago.


Has anyone used the drug Xeloda?? Please respond with side effects & effective Thanks?
Asked by Tamala Kettle 2 months ago.

yes i'm on it now. I haven't had many side effects, the other chemo drug is the worse one - the oxaliplatin. Xeloda actually hasn't affected me much, to the extent that when the oxaliplatin wears off but I'm still on Xeloda I'm back to the normal. I guess the only side effect I've had is a horrible taste in my mouth. Answered by Denyse Furtaw 2 months ago.

So, so much better than 5FU and Oxaliplatin which I endured for 6 months. Have been on Xeloda for almost 3 months and feel pretty good....regaining my strength back. Only thing is (I m not sure if it s the Oxaliplatin left-overs), I still have neuropathy. I use a TENS machine and essential oils to try and reverse the nerve damage. Neuropathy feels like this......I m on the beach and have FL sugar sand on my feet that I then insert inside of shoes without socks and walk in them. On top of this feeling is....I m on a ski trip and my feet are frozen (can t feel my toes). So now combine these two feelings and that s what my neuropathy feels like with occasional tingling up the wrists of my arms and also up the calves of my legs. But, I m encouraged by clean scans, and I hope you are cancer free too! Steve Answered by Riley Worrall 2 months ago.

Acupuncture, which involves inserting thin needles into various points on your body, may reduce peripheral neuropathy symptoms. Answered by Shauna Lopau 2 months ago.


What is the guide for determining the amount of xeloda PILLS that are given during chemo for colorectal cancer?
Microscopic cells that technology could not "see" three years ago were found in 3 out of 34 lymph nodes after surgery removed the entire stage 1 tumor...I know it is directed by body weight ; but I can find no guidelines... Asked by Reba Bucke 2 months ago.

If you have a T1 tumor and 3 of 34 lymph nodes positive you have a stage 3A cancer, assuming there are no mets. Xeloda is chemotherapy and I’m not sure the dosage is determined by body weight. I believe it is determined by the disease. Prescribing drugs is not part of my job or something I need to know, but if you have questions about any prescribed to you, you should speak to the doctor who prescribed it. If you need to know right now you can ask your pharmacist. Answered by Amina Hanafan 2 months ago.

My friend has this (almost exactly the same) her doctor said that they have to up the cancer from a T1 to a T3 to get insurance companies to pay for the chemo--I realize this was NOT your question yet it does apply...I assume you were also told there is a 65% chance you were cured with the surgery? Good luck and know you are in the prayers of people whom you will never meet.. Answered by Grayce Golab 2 months ago.


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