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Questions, experiences and reviews (16)

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How long does it take for Unisom sleep aid to leave your system?
A couple of nights ago I took three Unisom sleep aid tablets, but the directions said to take just one. I didn't think one would be enough and it was my first time taking Unisom. For the past two days I have been sleeping for 14 hours each night and feeling a little drowsy throughout the day. How long should it be until I am regular again and not so tired? I took it on 5/5/09
Pat R
  By now you should be fine. You are lucky you didn't OD
can i mix unisom and ibuprofen?
is it safe? unisom is the diphenhydramine hcl kind
son to the kel
  You can take them together with no problem at all.
Nurse For 21 Years
What is the difference between Unisom & Ambien?
I know that Ambien is a prescription and Unisom is not, but what are the actual differences? Which works better? Which has less side effects? Which has a high dosage? Etc.
  Unisom is an antihistamine, ambien is a hypnotic benzodiazepine, they are way different, ambien knocks you out when your in bed, unisom just makes you really tired. Ambien works better in my and most peoples opinion but it's just a preference thing.
joey e
benadryl doesn't really work for me anymore so was thinking of trying out doxylamine succinate aka unisom?
was just curious is this a similar feeling to benadryl cause benadryl knocked me out so im hoping i can get the same from the unisom tablets?
eric r
  Before you resort to any pharmaceutical drug, always check for the undesirable and dangerous side effects at to make an informed decision regarding the route you want to take.

The material below is an excerpt from this site regarding the side effects of Unisom.

Most COMMON side effects persist or become bothersome when using Unisom:

Anxiety, dizziness; drowsiness; dry mouth; headache; indigestion; loss of appetite; nausea; nervousness; stomach pain; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur when using Focalin XR Extended-Release Capsules:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; joint pain; purple or brownish red spots on the skin); behavior changes (eg, aggression, hostility, restlessness); blurred vision or other vision problems; chest pain; confusion; dark urine; fainting; fast or irregular heartbeat; fever, chills, or sore throat; hallucinations; mental or mood changes (eg, agitation, depression, irritability, panic attacks, persistent crying, severe or persistent anxiety, unusual sadness); one-sided weakness; seizures; severe or persistent dizziness or headache; shortness of breath; slurred speech; suicidal thoughts or attempts; tremor; uncontrolled speech or muscle movements; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur.
Can I take unisom sleep tabs the night before plastic surgery?
Im going to have breast lift reduction and implant surgery and I havent been able to sleep, just wondering if unisom is ok to take. I cant get ahold of my doctor on a sunday.
  not allowed at all drink some milk watch some chit chat prog tyra opera any thing but donot take it
how often can you take unisom during pregnancy?
I am 28.5 weeks, and I have not gotten any sleep in like 2 weeks until today when I gave in and took unisom. I was so tired I was having panic attacks, and couldnt breathe... My question is, when is it safe to take it again? I took it at noon, and now its 8 pm, and I want to sleep tonight. Can I take it? I dont want to overdose.
gina g
is it ok to take a product like unisom along with pepto bismal?
im nauseas but i wanna go to sleep to. i got the generic for unisom and am taking pepto bismal tablets also. is this ok?
  I have been taking both for about a week now. Nothing has happened to me.... So I guess it is safe.
I have found that with the pepto it does take a bit longer for the sleeping pill to work. I guess cause the pepto coats the stomach????

What is the Harm in Using Unisom sleep pills for 7 years?
I would like to know the long term effects of taking Unisom sleeping pills for 7 years. What happens to your body after such a long time use of the product. Doxylamine is the active ingrediant thanks
  your body looses it's ability to fall asleep naturally
Is it okay to take Unisom and Tramadol at the same time?
100 mg of unisom
150 mg of tramadol
Is this okay? Or will i become sick?
  call your pharmacist, walgreens are usually 24 hours.
Can I use Unisom If im using high blood pressure medication?
I'm using amlodipine for high blood pressure because of a kidney infection which is causing high blood pressure, can I take unisom?
Can someone die from taking the entire bottle of Unisom?
Wondering if one can die from taking the entire bottle--30 pills of the over the-counter, Unisom? Or would someone just have overdose symptons? Wondering if taking this many pills will shut down the liver or other organs? I am asking this for a friend. Any thoughtful replies will be appreciated.
What about taking the entire bottle with lithium?
has anyone ever mixed doxylamine succinate with diphenhydramine, aka unisom and benadryl?
do u think it would be safe?
  yes i have these two together many times and im still alive and sleeping.See i have this chronic sleep disorder that the doctor told me i would forever have to take medication. so between the meds the docs give is stronger and more deathly side effects i just deicded i would just stick with over the counter drugs.i been taking them for seven years and sleep everynite.
zsa zsa
Has anyone else taken OTC sleep meds like Unisom, and had their legs start hurting and jerking?
like 15 minutes after you lay down to go to sleep?
Alter E
  Alter E, I used to work graveyard shift and I took Unisom about once a week when i really needed some good sleep. Most of the time it worked great, but for some reason it would occasionally give me the same symptoms you described and i would end up not getting any good sleep at all. My legs would be very very jumpy and achey/tingley. This seemed to happen more often after i had been taking it for a while.
To my knowledge it never did any serious damage. But if you are worried you should see your doctor.
How many pills of Unisom to take to get a good high?
No dumb answers please, this is serious because my friend needs help.
And i'm NOT in middle school, my friend does this shit every morning before work and talks to 'people'
mandy dodo
  Unisom contains diphenhydramine. Have you ever heard on the news about a new surge of unisom abuse? That's because you can't get high from it. If you take enough you will have a delerious trip, which is a mind fuck and not fun at all. Try weed. And get out of middle school first.
Is Doxylamine Succinate (25mg) safe?
Been taking Unisom tabs which contains doxylamine succinate 25mg? Love my sleep now but is it bad to take 1/2 a pill per every evening?
  If half a pill works for you I would say thats good. Those pills never worked for me and my doctor ended up prescribing me ambien, which works amazing. I have to take ambien everyday and its a lot stronger than unisom so i don't see why it wouldn't be safe its a fairly low dose.
What is the maximum mg of Unisom Sleepgels that I can take in one dose?
I have insomia and I took the regular dose of 50 mg (1 soft-gels) and I did not go to sleep. I want to up the dosage up to 100 mg (2 soft-gels) so I can get some sleep; however, I also want to wake up in the morning. So, what is the max mg that is reasonable without killing myself and/or is 100 mg acceptable?
Jay D
  Read the label, that's what it's there for. Definitely do not take more than 3 doses per day. Do not use for more than 2 weeks. If you take sleeping pills often, you should probably see a doctor or search for other types of remedies like self-hypnosis or guided imagery.
M. HippocratEz

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Strange_Cee: wow i took fucking unisom sleeping pills 6 HOURS AGO! and im not sleepy . Wtf Unisom Your bunch of bitch ass liars lol
therealkbd: So nice thing about unisom - I got a good nights sleep. Bad thing about unisom - it makes me mean mommy next day. Not sure worth it.
Ez6000: I need me so Unisom
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Soleil_Boricua: I need a Unisom.. or anything PM
SaraaaHart: @amynichole_ don't take unisom.