Application Information

This drug has been submitted to the FDA under the reference 020408/001.

Names and composition

"TRUSOPT" is the commercial name of a drug composed of DORZOLAMIDE HYDROCHLORIDE.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
020408/001 TRUSOPT DORZOLAMIDE HYDROCHLORIDE SOLUTION/DROPS/OPHTHALMIC EQ 2% BASE

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
020408/001 TRUSOPT DORZOLAMIDE HYDROCHLORIDE SOLUTION/DROPS/OPHTHALMIC EQ 2% BASE
077846/001 DORZOLAMIDE HYDROCHLORIDE DORZOLAMIDE HYDROCHLORIDE SOLUTION/DROPS/OPHTHALMIC EQ 2% BASE
078395/001 DORZOLAMIDE HYDROCHLORIDE DORZOLAMIDE HYDROCHLORIDE SOLUTION/DROPS/OPHTHALMIC EQ 2% BASE
078748/001 DORZOLAMIDE HYDROCHLORIDE DORZOLAMIDE HYDROCHLORIDE SOLUTION/DROPS/OPHTHALMIC EQ 2% BASE
078756/001 DORZOLAMIDE HYDROCHLORIDE DORZOLAMIDE HYDROCHLORIDE SOLUTION/DROPS/OPHTHALMIC EQ 2% BASE
078981/001 DORZOLAMIDE HYDROCHLORIDE DORZOLAMIDE HYDROCHLORIDE SOLUTION/DROPS/OPHTHALMIC EQ 2% BASE
079186/001 DORZOLAMIDE HYDROCHLORIDE DORZOLAMIDE HYDROCHLORIDE SOLUTION/DROPS/OPHTHALMIC EQ 2% BASE
090143/001 DORZOLAMIDE HYDROCHLORIDE DORZOLAMIDE HYDROCHLORIDE SOLUTION/DROPS/OPHTHALMIC EQ 2% BASE
091034/001 DORZOLAMIDE HYDROCHLORIDE DORZOLAMIDE HYDROCHLORIDE SOLUTION/DROPS/OPHTHALMIC EQ 2% BASE
202053/001 DORZOLAMIDE HYDROCHLORIDE DORZOLAMIDE HYDROCHLORIDE SOLUTION/DROPS/OPHTHALMIC EQ 2% BASE

Ask a doctor

A licensed doctor will try to answer your question for free as quickly as possible. Free of charge during the beta period.

Answered questions

White discoloration of the hair?
This drug works by blocking a certain protein (vascular endothelial growth factor-VEGF), so I think he used avastin to stop bleeding, because she suffered bleeding intraocular. This is not my case I just heard about it so I cannot ask the doctor. Thanks :) Asked by Hana Hattley 1 year ago.

A diabetic patient 26 years old received avastin for glaucoma treatment (to lower the fluid pressure inside). She receives some eye drops, like trusopt, pred mild, ciloxan antibiotics, travatan, and xalacom. After receving the second avastin intraocular injection she start losing her scalp hair, and in the same time her eyebrows and eyelashes hair was changed into white. After her scalp hair started to get longer, it got to be white (it grew white instead of brown which was her hair color). What do you think the reason is (though i think it is avastin) and what is the best method to treat this and bring her hair color back to normal. Thanks Answered by Nada Dorge 1 year ago.

Let get the facts listed. Trusopt - contains Dorzolamide hydrochloride, Indicated for Ocular hypertension; glaucoma. Side effects conjunctivitis, keratitis, burning or stinging, eyelid inflammation or irritation, and blurred vision. Pred mild - contains Prednisolone acetate, indicated for inflammatory eye disorder. Side effects: It has more than 100 side effects in general! Ciloxan - indicated for bacterial infection. Side effects: gastrointestinal tract, CNS,skin Travatan - contains Travoprost. Indicated for glaucoma and ocular hypertension. Side effects: Darkening, thickening, and lengthening of eye lashes (Martindale) Xalacom - contains Latanoprost & timolol maleate Side effects: nausea, vomitting Avastin - contains Bevacizumab. Indicated for COLORECTAL CANCER. I wonder why doctor injected this drug. One of the side effects is hair loss.(1) Please check with your doctor why the patient is given Avastin (bevacizumab) Answered by Alphonso Krass 1 year ago.


Could my eyedrops be the reason why my eyelashes are almost always falling out?
I have maintainance for my eyes. Eyedrops for anti-glaucoma: alphagan P, trusopt, lumigan. Asked by Candice Calpin 1 year ago.

Unless your doing anything else to your eyes besides using eye drops on them, then its the eye drops. Answered by Deirdre Korzep 1 year ago.

Yes it could be the reason that why it falling out all the time. Answered by Kimberely Gondran 1 year ago.

eyelashes fall out very frequently and re-grow all the time.. eyedrops have nothin to do with that.. Answered by Patrick Stovel 1 year ago.

That could very well play a factor in your problem. Talk to your doctor! Answered by Juliann Fouch 1 year ago.

yes they could. um u might wanna see a dr to double check and to get something about that Answered by Lahoma Randal 1 year ago.

of course and perhaps rubbing them alot Answered by Marine Vangemert 1 year ago.

omg yes. get another brand of eye drops please Answered by Ivelisse Janney 1 year ago.


I Need a Doctors HELP or a nurse ...?
i have Gynecomastia .. just a little bit... but enough to make everything for me misssarable how do i know when it will go away... are there any signs any thing.... and i also have..these.. little .. bumps around them..... what are they ? Asked by Nick Cirilli 1 year ago.

Well, it differs for each individual, but if you've developed actual breast tissue, it's probably not going to just go away on its own. The surgery to remove breast buds from males is a pretty quick and easy one, with a very short recovery time, and very little scarring. And it's generally covered by health insurance. Do you mean little painless bumps of flesh on the nipple? If so, that's just a thing some people have. If it's larger lumps under the skin, it may be more breast tissue. Answered by Vincenzo Walentoski 1 year ago.


White discoloration of the hair?
A diabetic patient 26 years old received avastin for glaucoma treatment (to lower the fluid pressure inside). She receives some eye drops, like trusopt, pred mild, ciloxan antibiotics, travatan, and xalacom. After receving the second avastin intraocular injection she start losing her scalp hair, and in the same... Asked by Minda Tur 1 year ago.

A diabetic patient 26 years old received avastin for glaucoma treatment (to lower the fluid pressure inside). She receives some eye drops, like trusopt, pred mild, ciloxan antibiotics, travatan, and xalacom. After receving the second avastin intraocular injection she start losing her scalp hair, and in the same time her eyebrows and eyelashes hair was changed into white. After her scalp hair started to get longer, it got to be white (it grew white instead of brown which was her hair color). What do you think the reason is (though i think it is avastin) and what is the best method to treat this and bring her hair color back to normal. Thanks Answered by Valentine Gudinas 1 year ago.

All the eye drops have side effects. I cannot imagine one patient would be given a cocktail of the above. One at a time maybe. None of the side effects of Avastin (like hairloss) are likely to occur from injections into the eye. Can fear or stress or any extraordinary emotion change the color of your hair? Yes, but not instantly. Your psychological state has a significant impact on the hormones that can effect the amount of melanin deposited in each strand of hair, but the effect of emotion takes a long time to see. The hair you see on your head emerged from its follicle a long time ago. So, graying or any other color change is a gradual process, occurring over the course of several weeks, months, or years. In other words, counselling for stress and if distressed by the hair colour, go to a good hairdresser1 Answered by Kraig Hiteman 1 year ago.

i DIDNT UNDERSTAND MOST OF THAT CAUSE YOU USED BIG WORDS BUT FROM THE TITTLE ID SAY DYE YOUR HAIR!! Answered by Velvet Kessler 1 year ago.


Glaucoma experts please help?
there are many types and subtypes of glaucoma the open angle and the one which is narrowed or blocked angle glaucoma. There are many drugs used to manage these types of glaucoma. I have found out that adrenergic agonists(sympathomimetic) /alpha agonists are used to treat OPEN ANGLE glaucoma. My question is 1. why... Asked by Evie Condon 1 year ago.

there are many types and subtypes of glaucoma the open angle and the one which is narrowed or blocked angle glaucoma. There are many drugs used to manage these types of glaucoma. I have found out that adrenergic agonists(sympathomimetic) /alpha agonists are used to treat OPEN ANGLE glaucoma. My question is 1. why are these adrenergic agonists used in glaucoma when in fact they mimic the sympathetic response they cause pupillary dilation which increases intraocular pressure which is contraindicated in glaucoma, please explain how it can help in glaucoma if it causes pupil dilation? I have also found out that beta blockers(sympatholytic) suppress the sympathetic response causing pupil constriction decreasing intraocular pressure which helps in glaucoma. Cholinergic drugs/parasympatholytic mimic parasympathe response also helps by pupil constriction. and for open +narrow glaucoma 2. is my understanding correct? which drugs are used for which type? 3.why are benzodizepines not for glaucoma Answered by Chanell Steube 1 year ago.

There goes the answers to your questions: Adrenergic agonists are effective in reducing intra ocular pressure.. (IOP).. this is a well established fact... hteir mechanism of action is by increasing conventional trabecular uveoscleral outflow of aquoes from the anterior chamber of the eye so reducing the IOP. There are two types of adrenergic agonist... which are a) non selective: as epinephrin (eyedrops preparation called epifirin)... but although these agents decrease IOP they are no longer used in treating glaucoma due to multiple side effects... as irritation and mydriasis and CME and rapid tolerance.. you will hardly find any physician really treating glaucoma using epinephric nowadays.. b) selective adrenergic agonists:.. these agents selectively stimualte alpha 2 adrenergic receptors.. teh best known highly selective alpha 2 adrenergic agonist is brimonidine.. known in the market as Alphagan eyedrops.. very popular... that drug by selectively stimulating the alpha 2 receptors only will decrease IOP while avoiding the side effects that were caused by nonselective agents that stimulated all receptor types... so it doesn't cause pupil dilatation like the nonselective agents.. the drug Alphagan is used in markets widely nowadays and is a good effective drug and is a selective alpha 2 agonist.. As for Beta blockers.. .: they are effetive agents in reducion of IOP.. and they are still used in the market .. as Timolol.. or in the famous combination eyedrops Cosopt which is a combination of beta blocker and acetazolamide.. beta blockers do NOT cause pupilary constriction.. they just have systemic side effects that can be serious sometims and are contraindicated in some cases as asthma and heart block.. their mechanism of IOP reduction is by inhibiting cAMP production so reduce aquoes secretion.. you should not really try to explain the mechanism of action of every anti-glaucoma medicaiton by its effect on the pupil.. All of the antiglaucoma medications can be used in open angle and angle closure glaucoma.. with some prefernces of course.. however the important MIOTIC to use in termination of angle closrue glaucoma attack is Pilocarpine which is a parasympathomimetic agent.. directly acting on cholinergic receptors.. it does cause miosis.. but other than miosis it is a potent antiglaucoma medication that decreases IOP and can be used in treating open angle glaucoma but is no more in fashion due to side effects and the availbility of better medications nowadays.. one thing in your question: cholinergic drugs are parasympathomimetics not lytics.. that is they mimic parasypmathetic... like pilocarpine that act on end organ cholinergic receptors.. the betablocker eye drops doesn't act on the autonomic nervous system at all.. although it is a parasympatholyitic in theory... but it acts on teh beta receptors present on ciliary epithiliuem decreasing aqous producion.. i hope this is clear.. As for benzodiazepines .. it is a group of tranquilizer drugs.. why would it be used in glaucoma??!! .. you might have meant brinzolamide.. or acetazolamide.. and both belong to the group of carbonic anhydraze inhibitor.. .. both of these drugs are used in glaucoma treatment.. avaiable in teh market as eyedrops preparation Azopt (Alcon), and Trusopt (MSD).. and in combination as Cosopt (MSD) and acetazolamide can be takes orally as cidamex tabs or injections (Diamox) for management of acute glaucoma attacks.. hope that answers you.. you can contact me in case you need further elaboration.. Answered by Lashaunda Thomeczek 1 year ago.

Adrenergic agents like adrenalin are SYMPATHOMIMETIC and dilate pupil and are NEVER used in glaucoma..Parasympatholytics like atropine hyoscine also are NEVER used. Pilocarpine Acetyl choline Neostigmine and Physostigmine are parasympathomimetic and so can be used in glaucoma to constrict pupils. Diamox is a diuretic works by inhibiting the enzyme carbonic anhydrase and used specifically for glaucoma. Answered by Golda Mclauchlin 1 year ago.


What other medicines can be prescribed in place of Travatan for glaucoma?
Asked by Juan Seery 1 year ago.

Prostaglandin analogs like latanoprost (Xalatan), bimatoprost (Lumigan) and travoprost (Travatan) increase uveoscleral outflow of aqueous humor. Bimatoprost also increases trabecular outflow # Topical beta-adrenergic receptor antagonists such as timolol, levobunolol (Betagan), and betaxolol decrease aqueous humor production by the ciliary body. # Alpha2-adrenergic agonists such as brimonidine (Alphagan) work by a dual mechanism, decreasing aqueous production and increasing trabecular outflow. # Less-selective sympathomimetics like epinephrine and dipivefrin (Propine) increase outflow of aqueous humor through trabecular meshwork and possibly through uveoscleral outflow pathway, probably by a beta2-agonist action. # Miotic agents (parasympathomimetics) like pilocarpine work by contraction of the ciliary muscle, tightening the trabecular meshwork and allowing increased outflow of the aqueous humour. Ecothiopate is used in chronic glaucoma. # Carbonic anhydrase inhibitors like dorzolamide (Trusopt), brinzolamide (Azopt), acetazolamide (Diamox) lower secretion of aqueous humor by inhibiting carbonic anhydrase in the ciliary body. # Physostigmine is also used to treat glaucoma and delayed gastric emptying. # Medicinal marijuana is commonly used Answered by Jasmin Carabez 1 year ago.

weed (marijuana) Answered by Audrey Stehlik 1 year ago.


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