Application Information

This drug has been submitted to the FDA under the reference 018631/001.

Names and composition

"TRENTAL" is the commercial name of a drug composed of PENTOXIFYLLINE.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
018631/001 TRENTAL PENTOXIFYLLINE TABLET, EXTENDED RELEASE/ORAL 400MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
018631/001 TRENTAL PENTOXIFYLLINE TABLET, EXTENDED RELEASE/ORAL 400MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
074425/001 PENTOXIFYLLINE PENTOXIFYLLINE TABLET, EXTENDED RELEASE/ORAL 400MG
074874/001 PENTOXIFYLLINE PENTOXIFYLLINE TABLET, EXTENDED RELEASE/ORAL 400MG
074877/001 PENTOXIFYLLINE PENTOXIFYLLINE TABLET, EXTENDED RELEASE/ORAL 400MG
074878/001 PENTOXIFYLLINE PENTOXIFYLLINE TABLET, EXTENDED RELEASE/ORAL 400MG
074962/001 PENTOXIL PENTOXIFYLLINE TABLET, EXTENDED RELEASE/ORAL 400MG
075028/001 PENTOXIFYLLINE PENTOXIFYLLINE TABLET, EXTENDED RELEASE/ORAL 400MG
075093/001 PENTOXIFYLLINE PENTOXIFYLLINE TABLET, EXTENDED RELEASE/ORAL 400MG
075107/001 PENTOXIFYLLINE PENTOXIFYLLINE TABLET, EXTENDED RELEASE/ORAL 400MG
075191/001 PENTOXIFYLLINE PENTOXIFYLLINE TABLET, EXTENDED RELEASE/ORAL 400MG
075199/001 PENTOXIFYLLINE PENTOXIFYLLINE TABLET, EXTENDED RELEASE/ORAL 400MG

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Answered questions

Would trental (pentoxifylline) decrease blood pressure, specially diastolic blood pressure?
Asked by Mallory Yslas 1 year ago.

Trental reduces the viscosity or stickiness of your blood, allowing it to flow more freely. thus the heart would have to work less to pump blood. decreased resistance = decreased pressure Answered by Doloris Saysana 1 year ago.


Why doese Trental (pentoxyphillin)(vasodilator) causing sperm hypermotility?
Asked by Elna Mihaliak 1 year ago.

bc Trental combines with Myoplexia to produce hypozenia Answered by Nestor Vixay 1 year ago.


Has anyone ever used a medication called TRENTAL (Pentoxifylline) for circulation problems?
I am trying to help my grandfather who has circulation problems and his hands and feet get cold easy in the winter time. He is in good health overall, doesn't smoke, ect. His doctor mentioned a medication called TRENTAL...has anyone used this? What problems did you have? What positive benefits did you notice?... Asked by Odessa Hoeffer 1 year ago.

I am trying to help my grandfather who has circulation problems and his hands and feet get cold easy in the winter time. He is in good health overall, doesn't smoke, ect. His doctor mentioned a medication called TRENTAL...has anyone used this? What problems did you have? What positive benefits did you notice? What dose do you take and how often? Any other possible solutions for circulation problems like this besides the Trental? Answered by Rebecca Pienta 1 year ago.

He needs testing for peripheral vascular disease. The best first tests are ABI's & PVRs. If they are normal, Trental won't really help. If they are abnormal, he should see a vascular surgeon for evaluation. Answered by Enola Matas 1 year ago.


Can you take nyquil while taking trental?
Asked by Ghislaine Marmol 1 year ago.

Yes with a run of the mill treatment, but check with your doctor first if it is not. Answered by Eula Poffenroth 1 year ago.


Pentox(trental)/viagra/arginin... for peyronies?
Some people are using this mix of drugs with VED treatment, has anyone tried it and are you having any success? Asked by Mitchell Stratton 1 year ago.

Few penises are utterly immediately. I doubt it's as a result of masturbating. Peyronies ailment is precipitated via plaque construct up inside the penis and most commonly makes it curve upwards although sideways could also be feasible. I'm no longer a healthcare professional however I suspect you do not need it. It is correctable via an operation. Penises do bend reasonably obviously while erect so it should not be a challenge while you're ancient ample to have intercourse. If it does turn out to be a challenge seek advice a healthcare professional. Answered by Annabel Morreau 1 year ago.


What is the drug Trental used for and what are the side effects?
is this used for circulation in the feet and legs? or perhaps for other reasons Asked by Johnnie Villarreal 1 year ago.

It is really only used to help improve blood flow It lowers the viscosity of blood allowing it to flow easier, and improves red blood cell flexibility Answered by Dennise Kubitz 1 year ago.

Trental (pentoxifylline) is a drug used to treat intermittent claudication caused by chronic occlusive vascular disease. It is believed to improve blood flow and lower blood viscosity. The only side effects listed in the NDH 2003 are: CNS: headache,dizziness GI: Upset stomach, nausea, vomiting It is used to treat bad circulation in the feet and legs Answered by Shizue Dangler 1 year ago.

Trental (pentoxifylline), is a blood viscosity reducer. Yes, it can be used for circulation in the feet and legs. Side effects include headache, dizziness, nausea, vomiting, blurred vision, hypotension, flushing. Answered by Jonnie Kroner 1 year ago.

PAD is not a trivial disease. You should be following the instructions of your physician, not self-prescribing. If you're having problems paying for your prescriptions, ask your doctor if there is a generic or OTC medication he might prescribe. Also, check with the drug manufacturer; many of them have special programs to help people who can't afford to pay. Also, some supermarkets and mass marketers such as Walmart or Costco have special programs to offer all prescriptions on their approved list for a very low cost flat rate charge, often $4 or $5 per prescription. Walmart has a list of medications that are a flat $8 per prescription. Also, tell your doctor that you're having problems affording your prescription, and ask him if perhaps he might have some professional samples he could give you. Also, check with your County Health Department; they often have special prescription programs for low income people who can't afford their meds. If you work with your doctor to prescribe something on the list of low-cost meds, and explore your options, you'll probably find something you can afford. Answered by Marya Eisley 1 year ago.

Trental (Pentoxifylline) is an oral medication that improves the symptoms of blood flow problems, such as intermittent claudication. Pentoxifylline is also used to improve blood flow to the brain, prevent strokes, reduce muscle pain during exercise, manage sickle cell disease, as well as relieve nausea and headaches associated with high-altitude sickness. It can cause side effects such as can cause side effects such as nausea, vomiting, dizziness, nervousness, insomnia, and sweating. Answered by Cathey Makhija 1 year ago.

INDICATIONS TRENTAL is indicated for the treatment of patients with intermittent claudication on the basis of chronic occlusive arterial disease of the limbs. TRENTAL can improve function and symptoms but is not intended to replace more definitive therapy, such as surgical bypass, or removal of arterial obstructions when treating peripheral vascular disease. DOSAGE AND ADMINISTRATION The usual dosage of TRENTAL in controlled-release tablet form is one tablet (400 mg) three times a day with meals. While the effect of TRENTAL may be seen within 2 to 4 weeks, it is recommended that treatment be continued for at least 8 weeks. Efficacy has been demonstrated in double-blind clinical studies of 6 months duration. Digestive and central nervous system side effects are dose related. If patients develop these effects it is recommended that the dosage be lowered to one tablet twice a day (800 mg/day). If side effects persist at this lower dosage, the administration of TRENTAL should be discontinued. Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Trental. Trental's side effects are fairly uncommon. * Side effects may include: Allergic reaction (symptoms include: swelling of face, lips, tongue, throat, arms, or legs, sore throat, fever and chills, difficulty swallowing, chest pain), anxiety, bad taste in the mouth, blind spot in vision, blurred vision, brittle fingernails, chest pain (sometimes crushing), confusion, conjunctivitis (pinkeye), constipation, depression, difficult or labored breathing, dizziness, dry mouth/thirst, earache, excessive salivation, flu-like symptoms, fluid retention, general body discomfort, headache, hives, indigestion, inflammation of the gallbladder, itching, laryngitis, loss of appetite, low blood pressure, nosebleeds, rash, seizures, sore throat/swollen neck glands, stuffy nose, tremor, vomiting, weight change Answered by Simon Ferr 1 year ago.

It is a theophylline type drug for use in animals. Answered by Eufemia Mcthige 1 year ago.


Has anyone ever used a medication called TRENTAL (Pentoxifylline) for circulation problems?
I am trying to help my grandfather who has circulation problems and his hands and feet get cold easy in the winter time. He is in good health overall, doesn't smoke, ect. His doctor mentioned a medication called TRENTAL...has anyone used this? What problems did you have? What positive benefits did you notice?... Asked by Jolynn Trueax 1 year ago.

I am trying to help my grandfather who has circulation problems and his hands and feet get cold easy in the winter time. He is in good health overall, doesn't smoke, ect. His doctor mentioned a medication called TRENTAL...has anyone used this? What problems did you have? What positive benefits did you notice? What dose do you take and how often? Any other possible solutions for circulation problems like this besides the Trental? Answered by Florencia Yoshioka 1 year ago.

Yes, there are some natural ways to treat poor circulation. Cayenne or Capsicum (same herb) is excellent for increasing circulation. It is hot pepper. Take with food! Another herb that increases circulation to the extremeties is Ginko Biloba. You can take these herbs together, simultaneously, with no problems. A deodorized garlic supplement would also help. Cayenne strengthens the heart, too...while ginko biloba improves memory & helps improve erectile dysfunction, too. I know nothing about the medicine you mentioned. Sorry. Answered by Keeley Paustian 1 year ago.


What is the cause and treatment of unilateral tinnitus with normal audiogram?
I TOOK MEDICATIONS TRENTAL AND MULTIVITAMINS WITH NO IMPROVEMENT Asked by Esteban Dotolo 1 year ago.

Self-Help Techniques to Reduce Tinnitus: Avoid loud sound. Eliminate nicotine and caffeine. Avoid stressful situations. Rest. Get at least 8 hours of uninterrupted sleep every night. Avoid too much quiet. Use a fan, noisemaker (ocean waves, birds, rain sounds) or quiet radio music at night to mask the irritating tinnitus as you are trying to sleep. During the day, you may find yourself less bothered by the tinnitus if your mind and body are engaged in activities and there are other sounds in the room for your brain to listen to. Avoid focusing on the tinnitus by frequently discussing it with your family. In cases not responsive to these basic measures, treatment with the physician may include: Stress reduction Relaxation techniques including massage and acupuncture Treatment for depression and anxiety Sleeping aids Hearing aids to improve underlying hearing loss Family support Professional support groups such as the American Tinnitus Association Tinnitus Retraining Therapy Gingko biloba. Some patients find this herbal medication helpful, but the scientific data is inconclusive. Gingko biloba may increase the risk of bleeding. Answered by Jaclyn Sampey 1 year ago.


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