Application Information

This drug has been submitted to the FDA under the reference 019962/001.

Names and composition

"TOPROL-XL" is the commercial name of a drug composed of METOPROLOL SUCCINATE.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
019962/001 TOPROL-XL METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 50MG TARTRATE
019962/002 TOPROL-XL METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 100MG TARTRATE
019962/003 TOPROL-XL METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 200MG TARTRATE
019962/004 TOPROL-XL METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 25MG TARTRATE

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
019962/001 TOPROL-XL METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 50MG TARTRATE
019962/002 TOPROL-XL METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 100MG TARTRATE
019962/003 TOPROL-XL METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 200MG TARTRATE
019962/004 TOPROL-XL METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 25MG TARTRATE
076640/001 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 200MG TARTRATE
076640/002 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 100MG TARTRATE
076862/001 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 50MG TARTRATE
076969/001 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 25MG TARTRATE
076969/002 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 50MG TARTRATE
076969/003 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 100MG TARTRATE
076969/004 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 200MG TARTRATE
077118/001 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 25MG TARTRATE
077176/001 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 50MG TARTRATE
077298/001 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 100MG TARTRATE
077298/002 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 200MG TARTRATE
077779/001 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 25MG TARTRATE
078889/001 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 100MG TARTRATE
078889/002 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 200MG TARTRATE
090615/001 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 25MG TARTRATE
090615/002 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 50MG TARTRATE
090615/003 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 100MG TARTRATE
090615/004 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 200MG TARTRATE
090617/001 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 25MG TARTRATE
090617/002 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 50MG TARTRATE
202033/001 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 25MG TARTRATE
202033/002 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 50MG TARTRATE
202033/003 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 100MG TARTRATE
202033/004 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 200MG TARTRATE
204161/001 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 25MG TARTRATE
204161/002 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 50MG TARTRATE
204161/003 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 100MG TARTRATE
204161/004 METOPROLOL SUCCINATE METOPROLOL SUCCINATE TABLET, EXTENDED RELEASE/ORAL EQ 200MG TARTRATE

Ask a doctor

A licensed doctor will try to answer your question for free as quickly as possible. Free of charge during the beta period.

Answered questions

Has anyone was/is taking TOPROL-XL and have a knowlege if this medicine was withdrwan from market?
hi..time..reason i am asking.my mom was on this medicine since may be more then 3 yrs and suddenly pharmacy says the manufacter co of this medicine has stop making it and another co is now making it.i can't belive this things.do you know anything like that? Asked by Griselda Ellingburg 1 year ago.

Toprol-xl is a drug used to treat high blood pressure (hypertension). In can also be called Lopressor. Drug companies call the same drug by different names so patients know which company manufactured the drug. It is marketed under the brand name Lopressor or Lopresor, respectively, by Novartis, and Toprol-XL (in the USA); Selokeen (in the Netherlands); as Minax by Alphapharm (in Australia), Metrol by Arrow Pharmaceuticals (in Australia), as Betaloc by AstraZeneca, as Neobloc by Unipharm (in Israel) and as Corvitol by Berlin-Chemie AG. Novartis makes Toprol-XL which is the generic name for Lopressor. The shortage stems from problems at two big suppliers of the generic in the U.S. Novartis’s generics unit, Sandoz, recalled 6 million bottles of generic Toprol XL late last year, after the FDA sent the company a warning letter about the factory in North Carolina that makes the pills. Another supplier, KV Pharmaceutical, has fallen on hard times and said earlier this month that it would stop making and selling all of its products, including generic Toprol XL. The information available seems to be simply find another manufacturer of the drug. It isn't unusual for this to happen. And your mom shouldn't have any problem getting equally good treatment for her blood pressure. Answered by Lindsy Edgerson 1 year ago.

no it has not been withdrawn from the market. What are your reasons for asking this? TOPROL is a beta-blocker so it has effects on your lungs as well, but not as much as your heart. Answered by Vertie Cowels 1 year ago.


My husband has just started toprol xl 100 mg today. his b/p was 200/99. what are the side effects of thsi med.
is this a strong dose? he has had high b/p for a while but has finaly gone to our doctor. it runs in his family. he also has high colestorl. what are the side effects of this med.? he also has some pys. problems, he doesn"t take meds for them. could this med. make them worse. thanks Asked by Jannet Rihn 1 year ago.

I have taken Toprol XL for years. I had very few side effects. It can make you tired. It may also not be as sensitive to him while having sex. I had a hard time with organsisms as a women. I have a mitral valve prolapse that is why I took it and I was on 150 mg. I think the dose is corrrect. I also beleive that his BP may come down if his psy. problems are taken care of. Diet dose play a big part in his physical well being. Low fat, low salt, low caffine. Here is some information from Drug digest that might answer some questions for you. Remember, he may not have any side effects at all. His body will beomed used to it after a while. He may feel terrible for a couple of weeks becasue his BP is coming down and his body had to get used to being normal again. What drug(s) may interact with Toprol XL? •antiinflammatory drugs (NSAIDs, such as ibuprofen) •cimetidine •cocaine •fluoxetine •hawthorn •medicines for colds and breathing difficulties •medicines for diabetes •medicines for high blood pressure •medicines to control heart rhythm •medicines for malaria •monoamine oxidase inhibitors (Azilect®, Eldepryl®, Emsam®, Marplan®, Nardil®, Parnate®, Zelapar™) •rifampin •water pills Tell your prescriber or health care professional about all other medicines you are taking, including nonprescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines. What side effects may I notice from taking Toprol XL? Side effects that you should report to your prescriber or health care professional as soon as possible: •anxiety •cold, tingling, or numb hands or feet •difficulty breathing, wheezing •dizziness or fainting spells •increase in the amount of urine passed •increased thirst •irregular heartbeat •skin rash •slow heart rate (fewer than recommended by your prescriber or health care professional) •sweating •swollen legs or ankles •tremor, shakes •vomiting •weight loss Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome): •diarrhea •dry itching skin •headache •nausea •sexual difficulties, impotence •unusual tiredness Answered by Cody Happel 1 year ago.

I have been on the same dosage of Toprol XL for over 3 years now, and have never had a problem. As a matter of fact, my blood pressure is normal since taking this medication. Best of luck to you! Answered by Leroy Fenty 1 year ago.

I think mine was 50 mg It will make him drowse may effect love life too Answered by Claire Senseman 1 year ago.


Is it safe to stop taking Toprol XL (a beta blocker)?
My husband used to be 50 pounds overweight. His cardiologist put him on so many medications : pre diabetes pills, high chloresterol pills, high blood pressure pills, and beta blockers for a cardiac arrythmia. He has since lost the weight, and has discontinued all meds except the beta blockers. He is doing great, in... Asked by Latasha Schauwecker 1 year ago.

My husband used to be 50 pounds overweight. His cardiologist put him on so many medications : pre diabetes pills, high chloresterol pills, high blood pressure pills, and beta blockers for a cardiac arrythmia. He has since lost the weight, and has discontinued all meds except the beta blockers. He is doing great, in fact, he has never felt better. He would like to stop taking the Toprol as well, but I feel that all the cardiologist wants is money and is not at all concerned about his actual health. He will be 50 next month and does not want to be dependent on drugs all his life like his 80 year old mother. Can he safely stop the beta blocker by weaning himself off it like he did with all the other drugs? Answered by Ardella Erhard 1 year ago.

Toprol XL (metoprolol succinate) can be weaned off but to safely do so, your doctor should be the one instructing you on how your husband may go about it. Even though your husband may feel great, the beta blockers help his heart by controlling blood pressure, angina (chest pain) and possibly heart failure. Although your husband is uncomfortable with taking medications for the rest of his life, you have to keep an open mind that those medications could be possibly saving his life. I'm sorry you feel uncomfortable with your doctor, but it is extremely important that you keep communication with your cardiologist. The fact that you were refered to a cardiologist in the first place means that your husband needs help. The cardiologist doesn't make any money from writing perscriptions but rather, from the bi-annual check up and the occassional doctor visits. Try asking your friends and a couple nurses who they think is a good cardiologist. Perhaps you can transfer to that doctor. Answered by Erik Dymek 1 year ago.

Beta blockers can also be reduced by gradually tapering the dose. Before doing, however, one shud consult a doc as the ill effects if any which are notice during the weaning operation has to be taken care of. They are long acting drugs and hence ill effects show up somewhat late. Answered by Gertie Sission 1 year ago.


Toprol XL, effect on potency?
Hi :) my partner is on Toprol XL and we where wondering if that has an effect on his sperms. If we want to have a child, does he need to stop taking this beta blocker medicine for a while?I would not want him too, just curious. Asked by Andria Bernotas 1 year ago.

Maybe someone else has a more specific answer, but as far as I know Toprol XL would not affect sperm count. My daughter has the Long QT Gene--LQT-6, and also has a borderline time on her ECG for Long QT Syndrome. She has also had several "fainting" spells which may related to this heart situation, so is currently taking Toprol XL/25mg/day. She has been told that the Toprol XL is safe and necessary for her to stay on while pregnant, and is especially important after the baby is born. The highest risk for a Long QT patient is in the first 9 months after the baby is born. This may result from the added stress of motherhood, lack of sleep, and even the hormone changes associated with giving birth, breast feeding, etc. No one knows for sure why the risk is raised in the time after the baby is born, and not as much of a risk during the actual pregnancy. I digress because I'm trying to raise the awareness of Long QT Syndrone, as I lost my 22 year old daughter to undiagnosed LQTS, and my husband , myself, and my two living children, all have a gene for it. I have the LQT-2 gene defect, and the three of them have the LQT-6 gene defect. Answered by Clayton Chadd 1 year ago.

Metoprolol is used alone or in combination with other medications to treat high blood pressure. It also is used to prevent angina (chest pain) and to treat heart attacks. Extended-release (long-acting) metoprolol also is used in combination with other medications to treat heart failure. Metoprolol is in a class of medications called beta blockers. It works by slowing the heart rate and relaxing the blood vessels so the heart does not have to pump as hard. Do not stop taking metoprolol without talking to your doctor. Suddenly stopping metoprolol may cause chest pain or heart attack. Your doctor will probably decrease your dose gradually. Side effects:- Transient effects include dizziness, lightheadedness, drowsiness, tiredness, diarrhea, unusual dreams, ataxia, trouble sleeping, depression, and vision problems. It may also reduce blood flow to the hands and feet, causing them to feel numb and cold; smoking may worsen this effect. Serious side effects that are not to be tolerated for any length of time include symptoms of a very slow heartbeat (less than 50 bpm) (e.g. persistent dizziness, fainting, unusual fatigue), bluish discoloration of the fingers and toes, numbness/tingling/swelling of the hands or feet, sexual dysfunction, erectile dysfunction (impotence), hair loss, mental/mood changes, trouble breathing, cough, dyslipidemia, and increased thirst. Other highly unlikely symptoms include easy bruising or bleeding, persistent sore throat or fever, yellowing skin or eyes, stomach pain, dark urine, and persistent nausea. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness. Taking it with alcohol might cause mild body rashes and therefore is not recommended. Please see the web pages for more details on Metoprolol (generic name) Toprol (brand name). Answered by Billy Giroux 1 year ago.

She needs to see her Doc Answered by Lashonda Tinkham 1 year ago.


Toprol XL side effects?
I also feel like my breathing slows down a little bit... Maybe this pill is supposed to do that???? I have tachycardia, along with aortic stenosis also, so I do have a fast heart rate .... Asked by Margot Boga 1 year ago.

I just took my second dose of this medication, due to a heart condition I have and high blood pressure, with caused chest pains. Everytime I take a dose, I get this feeling. Almost like im "stoned". I get this heavy feeling in my head, and I feel almost, very calm and relaxed. I feel this way now, its just a weird, kind of scary feeling. I feel that if I try moving my head fast, that I will get a major dizzy spell. Is this a side effect, or should I talk to my cardiologist? Answered by Enriqueta Lach 1 year ago.

While all the side effects you have described are consistent with the use of this adrenoceptor blocker I would contact your cardiologist as a 'major dizzy spell' could be dangerous. The side effects list from MedicineNet: SIDE EFFECTS: Metoprolol is generally well tolerated. Side effects include abdominal cramps, diarrhea, constipation, fatigue, insomnia, nausea, depression, dreaming, memory loss, fever, impotence, lightheadedness, slow heart rate, low blood pressure, cold extremities, sore throat, and shortness of breath or wheezing. Metoprolol can aggravate breathing difficulties in patients with asthma, chronic bronchitis, or emphysema. Transient and serious side effects from the Wiki: Transient effects include dizziness, lightheadedness, drowsiness, tiredness, diarrhea, unusual dreams, ataxia, trouble sleeping, and vision problems. It may also reduce blood flow to the hands and feet, causing them to feel numb and cold; smoking may worsen this effect. Serious side effects that are not to be tolerated for any length of time include symptoms of a very slow heartbeat (less than 50 bpm) (e.g. persistent dizziness, fainting, unusual fatigue), bluish discoloration of the fingers and toes, numbness/tingling/swelling of the hands or feet, sexual dysfunction, erectile dysfunction (impotence), hair loss, mental/mood changes, trouble breathing, cough, and increased thirst. Other highly unlikely symptoms include easy bruising or bleeding, persistent sore throat or fever, yellowing skin or eyes, stomach pain, dark urine, and persistent nausea. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness. Taking it with alcohol might cause mild body rashes and therefore is not recommended From RxList: TOPROL-XL, metoprolol succinate, is a beta1-selective (cardioselective) adrenoceptor blocking agent, for oral administration, available as extended release tablets. TOPROL-XL has been formulated to provide a controlled and predictable release of metoprolol for once-daily administration. The tablets comprise a multiple unit system containing metoprolol succinate in a multitude of controlled release pellets. Each pellet acts as a separate drug delivery unit and is designed to deliver metoprolol continuously over the dosage interval. The tablets contain 23.75, 47.5, 95 and 190 mg of metoprolol succinate equivalent to 25, 50, 100 and 200 mg of metoprolol tartrate, USP, respectively. Its chemical name is (±)1-(isopropylamino)-3-[p-(2-methoxyeth...‡ phenoxy]-2-propanol succinate (2:1) (salt). Answered by Lianne Askin 1 year ago.


Toprol XL problems?
Has anybody here had any problems with the prescription drug Toprol XL, for high blood pressure? I don't like it, but my doctor insists that I need to take it. It seems to cause some unpleasant side effects. Asked by Trinh Falcioni 1 year ago.

...ahh, you are the same person that asked about the HCTZ! Well...Toprol XL is known to cause more side effects than other blood pressure medications...fatigue, dizziness, depression, impotence, etc...(not to mention, it is fairly expensive). But it is still an excellent drug that most people have no side effects with. In the end, you don't have to take any medications! But if your blood pressure is high and untreated, you are likely to have a stroke or heart attack. If you are fortunate enough to survive the stroke and/or heart attack, you may not have a fully functioning body, heart, or mind...for the rest of your life. I would stick with the HCTZ...and also try an ACE-inhibitor (like lisinopril or enalapril). Most people tolerate these without many side effects...(they are both extremely inexpensive, too)... But if you really hate medications, getting some regular aerobic activity, losing weight, stop smoking (if you do), and eating healthier can help blood pressure some. (and this should be done, anyway, of course). But hopefully, you can find some way to control your blood pressure...with medications that are tolerable with you...to avoid all the problems that untreated high blood pressure bring... Weigh the risks with the benefits...discuss with your doctor...and I hope you can come to an agreement together. Some classes of medications for blood pressure are better for certain patients than others, too... Good luck. Answered by Damian Heinitz 1 year ago.

extreme blood pressure may reason sexual sickness in men. And antihypertensive meds may also reason sexual sickness in men. As for utilising something like Viagra with antihypertensive meds, the guy to ask is your clinical specialist, whom you are able to ought to communicate over with besides to get a prescription for the viagra. Answered by Jerry Reckley 1 year ago.


What are the withdrawal effects of toprol xl??
my mom is on the 50 mg and she wants to get off of it slowly to take another medication.( i don't know the name of it). and she wants to know how to get off of it safely and what are the withdrawal effects?? Asked by Juan Bursell 1 year ago.

Toprol XL should be taken continuously. When ending Toprol (Metoprolol) treatments, dosage should be lowered gradually over a period of about 2 weeks. Do not stop taking this drug unless directed to do so by your doctor, abrupt withdrawal may cause chest pain, breathing difficulties,increased sweating, and unusually fast or irregular heartbeat. It is best to take this medication at the same time every day. There are other beta blockers that she can try including: Sectral (acebutolol), Tenormin (atenolol), Zebeta (bisoprolol), Corgard (nadolol), Bystolic, Blocadren (timolol), or the doctor can change her medication to an ARB (Angiotensin II receptor Blockers): Diovan & HCTZ, Lotrel, etc. Answered by Major Keath 1 year ago.

My husband was just prescribed this and its awful. You cant stop cold turkey, you have to wean yourself. The best way to do this is to call the doctor. If she didnt have any of the side effects of the drug then she shouldnt have withdrawal effects. All it does is slow your heart rate down so if shes off of it and has a past with rapid heart rates then her heart rate might speed back up. Either way she needs to call the doctor or even a pharmacist to see what they suggest. Answered by Lemuel Macari 1 year ago.

She needs to see her Doc Answered by Somer Blyze 1 year ago.


Long Term Affects With Using Toprol XL And Other Beta Blockers?
What is the long term bad affects of taking beta blockers like toprol xl when you take it for awhile or the rest of your life Asked by Elenora Muckey 1 year ago.

Toprol XL is an extended release version of Metoprolol. It's a B1 Selective adrenoreceptor blocker, meaning it is cardioselective. Basically since it's B1 selective it means that it usually does not interfere with b2 adrenoreceptors which are primarily in the lungs/bronchial system. Sometimes at very high dosages there can be some effect on B2 receptors. As far as long term side effects are concerned, new evidence (2006) has shown that Beta Blockers have a higher risk for acquiring type 2 diabetes. It was actually downgraded to option #4 for treatment of hypertension because of this risk. Answered by Sol Hymon 1 year ago.

I honestly dont know what Toprol XL is but I take Propranolol which is one, for migraines. I am not positive if its this med or others I take for COPD and asthma, but one of them has made me sunlight sensitive and I get welts when I get sunburned. As for other side effects, I havent noticed any and I have been taking it for 4 yrs now. Answered by Alicia Zanderigo 1 year ago.


What all is toprol XL 50MG Tablet SA AST used for? my doctor put me on this back in january for my anxiety.?
I havent taken it yet because i dont know alot about it. Asked by Lauretta Silton 1 year ago.

Toprol XL contains the drug metoprolol tartrate, which is known as a beta blocker. It is generally used in the treatment of high blood pressure, angina pectoris (chest pain, usually caused by lack of oxygen to the heart due to clogged arteries), and heart attack. When prescribed for high blood pressure, it is effective when used alone or in combination with other high blood pressure medications. Beta blockers decrease the force and rate of heart contractions, thereby reducing the demand for oxygen and lowering blood pressure. Occasionally doctors prescribe metoprolol for prevention of migraine headache, and relief of temporary anxiety. Answered by Roberto Simmons 1 year ago.

its primarily a medication that eases the workload on your heart and gets more oxygen to the heart, but it can also be prescribed for managing anxiety symptoms. Do you ever notice when you have anxiety that your heart is racing? Toprol will help keep your heart rate controlled. P.S. Don't take more than what your Dr prescribes because Toprol does lower your heart rate. Answered by Lenore Eslava 1 year ago.

It is a beta receptor blocker. It is most commonly used for high blood pressure, fast heart rate, and other cardiac abnormalities. It can also be used to prevent migraines. It's a very popular medication, but it can have some serious side effects. It's not likely that you will experience these if you have been on it since January, but you may want to talk to your pharmacist if you are having specific concerns. Answered by Cherryl Debus 1 year ago.


Has anyone was/is taking TOPROL-XL and have a knowlege if this medicine was withdrwan from market?
hi..time..reason i am asking.my mom was on this medicine since may be more then 3 yrs and suddenly pharmacy says the manufacter co of this medicine has stop making it and another co is now making it.i can't belive this things.do you know anything like that? Asked by Krystin Zita 1 year ago.

Toprol-xl is a drug used to treat high blood pressure (hypertension). In can also be called Lopressor. Drug companies call the same drug by different names so patients know which company manufactured the drug. It is marketed under the brand name Lopressor or Lopresor, respectively, by Novartis, and Toprol-XL (in the USA); Selokeen (in the Netherlands); as Minax by Alphapharm (in Australia), Metrol by Arrow Pharmaceuticals (in Australia), as Betaloc by AstraZeneca, as Neobloc by Unipharm (in Israel) and as Corvitol by Berlin-Chemie AG. Novartis makes Toprol-XL which is the generic name for Lopressor. The shortage stems from problems at two big suppliers of the generic in the U.S. Novartis’s generics unit, Sandoz, recalled 6 million bottles of generic Toprol XL late last year, after the FDA sent the company a warning letter about the factory in North Carolina that makes the pills. Another supplier, KV Pharmaceutical, has fallen on hard times and said earlier this month that it would stop making and selling all of its products, including generic Toprol XL. The information available seems to be simply find another manufacturer of the drug. It isn't unusual for this to happen. And your mom shouldn't have any problem getting equally good treatment for her blood pressure. Answered by Stephenie Kozar 1 year ago.

no it has not been withdrawn from the market. What are your reasons for asking this? TOPROL is a beta-blocker so it has effects on your lungs as well, but not as much as your heart. Answered by Onita Balaam 1 year ago.


My husband has just started toprol xl 100 mg today. his b/p was 200/99. what are the side effects of thsi med.
is this a strong dose? he has had high b/p for a while but has finaly gone to our doctor. it runs in his family. he also has high colestorl. what are the side effects of this med.? he also has some pys. problems, he doesn"t take meds for them. could this med. make them worse. thanks Asked by Emily Rhodes 1 year ago.

I have taken Toprol XL for years. I had very few side effects. It can make you tired. It may also not be as sensitive to him while having sex. I had a hard time with organsisms as a women. I have a mitral valve prolapse that is why I took it and I was on 150 mg. I think the dose is corrrect. I also beleive that his BP may come down if his psy. problems are taken care of. Diet dose play a big part in his physical well being. Low fat, low salt, low caffine. Here is some information from Drug digest that might answer some questions for you. Remember, he may not have any side effects at all. His body will beomed used to it after a while. He may feel terrible for a couple of weeks becasue his BP is coming down and his body had to get used to being normal again. What drug(s) may interact with Toprol XL? •antiinflammatory drugs (NSAIDs, such as ibuprofen) •cimetidine •cocaine •fluoxetine •hawthorn •medicines for colds and breathing difficulties •medicines for diabetes •medicines for high blood pressure •medicines to control heart rhythm •medicines for malaria •monoamine oxidase inhibitors (Azilect®, Eldepryl®, Emsam®, Marplan®, Nardil®, Parnate®, Zelapar™) •rifampin •water pills Tell your prescriber or health care professional about all other medicines you are taking, including nonprescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines. What side effects may I notice from taking Toprol XL? Side effects that you should report to your prescriber or health care professional as soon as possible: •anxiety •cold, tingling, or numb hands or feet •difficulty breathing, wheezing •dizziness or fainting spells •increase in the amount of urine passed •increased thirst •irregular heartbeat •skin rash •slow heart rate (fewer than recommended by your prescriber or health care professional) •sweating •swollen legs or ankles •tremor, shakes •vomiting •weight loss Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome): •diarrhea •dry itching skin •headache •nausea •sexual difficulties, impotence •unusual tiredness Answered by Sherie Ogarro 1 year ago.

I have been on the same dosage of Toprol XL for over 3 years now, and have never had a problem. As a matter of fact, my blood pressure is normal since taking this medication. Best of luck to you! Answered by Yu Carpinello 1 year ago.

I think mine was 50 mg It will make him drowse may effect love life too Answered by Rosalva Mathena 1 year ago.


Is it safe to stop taking Toprol XL (a beta blocker)?
My husband used to be 50 pounds overweight. His cardiologist put him on so many medications : pre diabetes pills, high chloresterol pills, high blood pressure pills, and beta blockers for a cardiac arrythmia. He has since lost the weight, and has discontinued all meds except the beta blockers. He is doing great, in... Asked by Santiago Leemans 1 year ago.

My husband used to be 50 pounds overweight. His cardiologist put him on so many medications : pre diabetes pills, high chloresterol pills, high blood pressure pills, and beta blockers for a cardiac arrythmia. He has since lost the weight, and has discontinued all meds except the beta blockers. He is doing great, in fact, he has never felt better. He would like to stop taking the Toprol as well, but I feel that all the cardiologist wants is money and is not at all concerned about his actual health. He will be 50 next month and does not want to be dependent on drugs all his life like his 80 year old mother. Can he safely stop the beta blocker by weaning himself off it like he did with all the other drugs? Answered by Jarred Arispe 1 year ago.

Toprol XL (metoprolol succinate) can be weaned off but to safely do so, your doctor should be the one instructing you on how your husband may go about it. Even though your husband may feel great, the beta blockers help his heart by controlling blood pressure, angina (chest pain) and possibly heart failure. Although your husband is uncomfortable with taking medications for the rest of his life, you have to keep an open mind that those medications could be possibly saving his life. I'm sorry you feel uncomfortable with your doctor, but it is extremely important that you keep communication with your cardiologist. The fact that you were refered to a cardiologist in the first place means that your husband needs help. The cardiologist doesn't make any money from writing perscriptions but rather, from the bi-annual check up and the occassional doctor visits. Try asking your friends and a couple nurses who they think is a good cardiologist. Perhaps you can transfer to that doctor. Answered by Leonora Thiery 1 year ago.

Beta blockers can also be reduced by gradually tapering the dose. Before doing, however, one shud consult a doc as the ill effects if any which are notice during the weaning operation has to be taken care of. They are long acting drugs and hence ill effects show up somewhat late. Answered by Desire Salser 1 year ago.


Toprol XL, effect on potency?
Hi :) my partner is on Toprol XL and we where wondering if that has an effect on his sperms. If we want to have a child, does he need to stop taking this beta blocker medicine for a while?I would not want him too, just curious. Asked by Jesus Perdew 1 year ago.

Maybe someone else has a more specific answer, but as far as I know Toprol XL would not affect sperm count. My daughter has the Long QT Gene--LQT-6, and also has a borderline time on her ECG for Long QT Syndrome. She has also had several "fainting" spells which may related to this heart situation, so is currently taking Toprol XL/25mg/day. She has been told that the Toprol XL is safe and necessary for her to stay on while pregnant, and is especially important after the baby is born. The highest risk for a Long QT patient is in the first 9 months after the baby is born. This may result from the added stress of motherhood, lack of sleep, and even the hormone changes associated with giving birth, breast feeding, etc. No one knows for sure why the risk is raised in the time after the baby is born, and not as much of a risk during the actual pregnancy. I digress because I'm trying to raise the awareness of Long QT Syndrone, as I lost my 22 year old daughter to undiagnosed LQTS, and my husband , myself, and my two living children, all have a gene for it. I have the LQT-2 gene defect, and the three of them have the LQT-6 gene defect. Answered by Odis Auzenne 1 year ago.

Metoprolol is used alone or in combination with other medications to treat high blood pressure. It also is used to prevent angina (chest pain) and to treat heart attacks. Extended-release (long-acting) metoprolol also is used in combination with other medications to treat heart failure. Metoprolol is in a class of medications called beta blockers. It works by slowing the heart rate and relaxing the blood vessels so the heart does not have to pump as hard. Do not stop taking metoprolol without talking to your doctor. Suddenly stopping metoprolol may cause chest pain or heart attack. Your doctor will probably decrease your dose gradually. Side effects:- Transient effects include dizziness, lightheadedness, drowsiness, tiredness, diarrhea, unusual dreams, ataxia, trouble sleeping, depression, and vision problems. It may also reduce blood flow to the hands and feet, causing them to feel numb and cold; smoking may worsen this effect. Serious side effects that are not to be tolerated for any length of time include symptoms of a very slow heartbeat (less than 50 bpm) (e.g. persistent dizziness, fainting, unusual fatigue), bluish discoloration of the fingers and toes, numbness/tingling/swelling of the hands or feet, sexual dysfunction, erectile dysfunction (impotence), hair loss, mental/mood changes, trouble breathing, cough, dyslipidemia, and increased thirst. Other highly unlikely symptoms include easy bruising or bleeding, persistent sore throat or fever, yellowing skin or eyes, stomach pain, dark urine, and persistent nausea. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness. Taking it with alcohol might cause mild body rashes and therefore is not recommended. Please see the web pages for more details on Metoprolol (generic name) Toprol (brand name). Answered by Kerri Theodore 1 year ago.

She needs to see her Doc Answered by Lelah Tara 1 year ago.


Toprol XL side effects?
I also feel like my breathing slows down a little bit... Maybe this pill is supposed to do that???? I have tachycardia, along with aortic stenosis also, so I do have a fast heart rate .... Asked by Faustina Gennett 1 year ago.

I just took my second dose of this medication, due to a heart condition I have and high blood pressure, with caused chest pains. Everytime I take a dose, I get this feeling. Almost like im "stoned". I get this heavy feeling in my head, and I feel almost, very calm and relaxed. I feel this way now, its just a weird, kind of scary feeling. I feel that if I try moving my head fast, that I will get a major dizzy spell. Is this a side effect, or should I talk to my cardiologist? Answered by Jamison Wolter 1 year ago.

While all the side effects you have described are consistent with the use of this adrenoceptor blocker I would contact your cardiologist as a 'major dizzy spell' could be dangerous. The side effects list from MedicineNet: SIDE EFFECTS: Metoprolol is generally well tolerated. Side effects include abdominal cramps, diarrhea, constipation, fatigue, insomnia, nausea, depression, dreaming, memory loss, fever, impotence, lightheadedness, slow heart rate, low blood pressure, cold extremities, sore throat, and shortness of breath or wheezing. Metoprolol can aggravate breathing difficulties in patients with asthma, chronic bronchitis, or emphysema. Transient and serious side effects from the Wiki: Transient effects include dizziness, lightheadedness, drowsiness, tiredness, diarrhea, unusual dreams, ataxia, trouble sleeping, and vision problems. It may also reduce blood flow to the hands and feet, causing them to feel numb and cold; smoking may worsen this effect. Serious side effects that are not to be tolerated for any length of time include symptoms of a very slow heartbeat (less than 50 bpm) (e.g. persistent dizziness, fainting, unusual fatigue), bluish discoloration of the fingers and toes, numbness/tingling/swelling of the hands or feet, sexual dysfunction, erectile dysfunction (impotence), hair loss, mental/mood changes, trouble breathing, cough, and increased thirst. Other highly unlikely symptoms include easy bruising or bleeding, persistent sore throat or fever, yellowing skin or eyes, stomach pain, dark urine, and persistent nausea. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness. Taking it with alcohol might cause mild body rashes and therefore is not recommended From RxList: TOPROL-XL, metoprolol succinate, is a beta1-selective (cardioselective) adrenoceptor blocking agent, for oral administration, available as extended release tablets. TOPROL-XL has been formulated to provide a controlled and predictable release of metoprolol for once-daily administration. The tablets comprise a multiple unit system containing metoprolol succinate in a multitude of controlled release pellets. Each pellet acts as a separate drug delivery unit and is designed to deliver metoprolol continuously over the dosage interval. The tablets contain 23.75, 47.5, 95 and 190 mg of metoprolol succinate equivalent to 25, 50, 100 and 200 mg of metoprolol tartrate, USP, respectively. Its chemical name is (±)1-(isopropylamino)-3-[p-(2-methoxyeth...‡ phenoxy]-2-propanol succinate (2:1) (salt). Answered by Judy Tippet 1 year ago.


Toprol XL problems?
Has anybody here had any problems with the prescription drug Toprol XL, for high blood pressure? I don't like it, but my doctor insists that I need to take it. It seems to cause some unpleasant side effects. Asked by Roma Walkins 1 year ago.

...ahh, you are the same person that asked about the HCTZ! Well...Toprol XL is known to cause more side effects than other blood pressure medications...fatigue, dizziness, depression, impotence, etc...(not to mention, it is fairly expensive). But it is still an excellent drug that most people have no side effects with. In the end, you don't have to take any medications! But if your blood pressure is high and untreated, you are likely to have a stroke or heart attack. If you are fortunate enough to survive the stroke and/or heart attack, you may not have a fully functioning body, heart, or mind...for the rest of your life. I would stick with the HCTZ...and also try an ACE-inhibitor (like lisinopril or enalapril). Most people tolerate these without many side effects...(they are both extremely inexpensive, too)... But if you really hate medications, getting some regular aerobic activity, losing weight, stop smoking (if you do), and eating healthier can help blood pressure some. (and this should be done, anyway, of course). But hopefully, you can find some way to control your blood pressure...with medications that are tolerable with you...to avoid all the problems that untreated high blood pressure bring... Weigh the risks with the benefits...discuss with your doctor...and I hope you can come to an agreement together. Some classes of medications for blood pressure are better for certain patients than others, too... Good luck. Answered by Trinity Tejadilla 1 year ago.

extreme blood pressure may reason sexual sickness in men. And antihypertensive meds may also reason sexual sickness in men. As for utilising something like Viagra with antihypertensive meds, the guy to ask is your clinical specialist, whom you are able to ought to communicate over with besides to get a prescription for the viagra. Answered by Marcie Burick 1 year ago.


What are the withdrawal effects of toprol xl??
my mom is on the 50 mg and she wants to get off of it slowly to take another medication.( i don't know the name of it). and she wants to know how to get off of it safely and what are the withdrawal effects?? Asked by Beau Cupelli 1 year ago.

Toprol XL should be taken continuously. When ending Toprol (Metoprolol) treatments, dosage should be lowered gradually over a period of about 2 weeks. Do not stop taking this drug unless directed to do so by your doctor, abrupt withdrawal may cause chest pain, breathing difficulties,increased sweating, and unusually fast or irregular heartbeat. It is best to take this medication at the same time every day. There are other beta blockers that she can try including: Sectral (acebutolol), Tenormin (atenolol), Zebeta (bisoprolol), Corgard (nadolol), Bystolic, Blocadren (timolol), or the doctor can change her medication to an ARB (Angiotensin II receptor Blockers): Diovan & HCTZ, Lotrel, etc. Answered by Adrianne Peavy 1 year ago.

My husband was just prescribed this and its awful. You cant stop cold turkey, you have to wean yourself. The best way to do this is to call the doctor. If she didnt have any of the side effects of the drug then she shouldnt have withdrawal effects. All it does is slow your heart rate down so if shes off of it and has a past with rapid heart rates then her heart rate might speed back up. Either way she needs to call the doctor or even a pharmacist to see what they suggest. Answered by Daryl Cronenberg 1 year ago.

She needs to see her Doc Answered by Bambi Ringuette 1 year ago.


Long Term Affects With Using Toprol XL And Other Beta Blockers?
What is the long term bad affects of taking beta blockers like toprol xl when you take it for awhile or the rest of your life Asked by Susannah Highnote 1 year ago.

Toprol XL is an extended release version of Metoprolol. It's a B1 Selective adrenoreceptor blocker, meaning it is cardioselective. Basically since it's B1 selective it means that it usually does not interfere with b2 adrenoreceptors which are primarily in the lungs/bronchial system. Sometimes at very high dosages there can be some effect on B2 receptors. As far as long term side effects are concerned, new evidence (2006) has shown that Beta Blockers have a higher risk for acquiring type 2 diabetes. It was actually downgraded to option #4 for treatment of hypertension because of this risk. Answered by Marylin Mizell 1 year ago.

I honestly dont know what Toprol XL is but I take Propranolol which is one, for migraines. I am not positive if its this med or others I take for COPD and asthma, but one of them has made me sunlight sensitive and I get welts when I get sunburned. As for other side effects, I havent noticed any and I have been taking it for 4 yrs now. Answered by Wei Blaeser 1 year ago.


What all is toprol XL 50MG Tablet SA AST used for? my doctor put me on this back in january for my anxiety.?
I havent taken it yet because i dont know alot about it. Asked by Isadora Ruggiere 1 year ago.

Toprol XL contains the drug metoprolol tartrate, which is known as a beta blocker. It is generally used in the treatment of high blood pressure, angina pectoris (chest pain, usually caused by lack of oxygen to the heart due to clogged arteries), and heart attack. When prescribed for high blood pressure, it is effective when used alone or in combination with other high blood pressure medications. Beta blockers decrease the force and rate of heart contractions, thereby reducing the demand for oxygen and lowering blood pressure. Occasionally doctors prescribe metoprolol for prevention of migraine headache, and relief of temporary anxiety. Answered by Scott Glauberman 1 year ago.

its primarily a medication that eases the workload on your heart and gets more oxygen to the heart, but it can also be prescribed for managing anxiety symptoms. Do you ever notice when you have anxiety that your heart is racing? Toprol will help keep your heart rate controlled. P.S. Don't take more than what your Dr prescribes because Toprol does lower your heart rate. Answered by Melani Wester 1 year ago.

It is a beta receptor blocker. It is most commonly used for high blood pressure, fast heart rate, and other cardiac abnormalities. It can also be used to prevent migraines. It's a very popular medication, but it can have some serious side effects. It's not likely that you will experience these if you have been on it since January, but you may want to talk to your pharmacist if you are having specific concerns. Answered by Elisabeth Rosasco 1 year ago.


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