SUBUTEX Ressources

Application Information

This drug has been submitted to the FDA under the reference 020732/002.

Names and composition

"SUBUTEX" is the commercial name of a drug composed of BUPRENORPHINE HYDROCHLORIDE.
It belongs to the class Opiate dependence treatments and is used in Opiate dependence (Poisoning and Drug Dependence)

Answered questions

Is Subutex safer than Methadone while pregnant?
Asked by Ellen Mazique 4 months ago.

throughout the time of being pregnant- risk-free Methadone Dosage- For persistent soreness sufferers (sure human beings, methdone is a wide-unfold and extremely risk-free medicine for individuals with neurogenic persistent soreness - not something to do with drug abuse) as much as 40 mg./ day at 10mg/ q.4 periods For substance abuse i think this is as much as a hundred and twenty mgs. i don't understand with regards to the subutex, yet with the two med you will choose monitoring with the aid of a perinatologist just to be risk-free, in spite of the shown fact that they are not often mandatory. Answered by Sommer Laliberty 4 months ago.

Please talk with a doctor about taking any medication or any type of drugs while pregnant. Answered by Roderick Lichota 4 months ago.

This is a question I'd be asking my doctor.... Answered by Leona Yidiaris 4 months ago.


Does subutex block other opiates from being viable..does it work just like suboxone?
I'm wondering if subutex allows the use of other painkillers or are the receptors blocked the way suboxone blocks the receptors and if so what are main differences between the two drugs.. Asked by Diane Handshaw 4 months ago.

suboxone and subutex block other opiates. you can't use opiates on top of it unless at very very very high amounts and that could kill you. my other answer to your subutex question has the details on the difference between suboxone and subutex. Let's look at an example: Subutex/Suboxone's main ingredient that works its magic, is buprenorphine or bupe. Say someone was dependent on 200mg of morphine IV. Now if you give this person suboxone or subutex, it will kick all the morphine off of the receptors. Bupe then binds to the receptors, but because it has a ceiling effect, you only get the approximate equivalent of 20mg morphine IV. So for a person dependent on 200mg, this is no different from giving him/her a shot of narcan. you will be in withdrawals either way. There are some people who claim to be able to use certain painkillers on top of bupe. Ultram in particular seems to have an effect. This is not due to ultram binding to the opiate receptors but rather from ultram's effects on serotonin and nor-epinephrine. you may be able to use certain opiate painkillers (the much stronger ones like dliaudid or numorphan) on top of bupe, but only if you are on a very low dosage of bupe. remember this: 2mg of subutex/suboxone will block up to 40% of all the available opiate receptors. 16mg of subutex/suboxone will block more than 80%. Answered by Paulita Eichenauer 4 months ago.

Subtex will block other opiates and their effects. Answered by Lachelle Stabs 4 months ago.


Methadone or Subutex?
Which one is easier to detox from? I have heard horror stories about both of them. People say that sub is just as hard to get off of as the methadone. Most Dr's say Sub is easier.. I am just curious. My son is on Subutex. Thanks! Asked by Bari Valenzuela 4 months ago.

Either can be difficult to detox from but the reason that many people have an easier time with Subutex is that it works by being what's called a "partial agonist" to the opioid receptors in the brain. What that means is, it helps the body think that there is actual drug in the receptor, but it's not a true "full-on-opiate" I hope this helps! Answered by Heather Masello 4 months ago.

During Pregnancy- Safe Methadone Dosage- For continual affliction sufferers (Yes men and women, methdone is a COMMONLY USED and VERY SAFE remedy for men and women with neurogenic continual affliction - NOTHING to do with drug abuse) as much as forty mg./ day at 10mg/ q.four periods For substance abuse I consider it's as much as a hundred and twenty mgs. I do not know approximately the subutex, however with both med you're going to want tracking through a perinatologist simply to be trustworthy, even though they're not often wanted. Answered by Deloise Haack 4 months ago.


Advice for methadone to subutex switch.?
I have been on methadone for about 18 months. I am on 80 mg. My last dose was Saturday the 7th on November. I've been doing other opiates to get by. I have a prescription for subutex not suboxone how long before I should try to switch. I have to go away on training for a new manager job and had to switch. I... Asked by Carma Hueser 4 months ago.

I have been on methadone for about 18 months. I am on 80 mg. My last dose was Saturday the 7th on November. I've been doing other opiates to get by. I have a prescription for subutex not suboxone how long before I should try to switch. I have to go away on training for a new manager job and had to switch. I heard these were easier to get off anyway. Answered by Donald Aley 4 months ago.

Subutex doesn't contain the Naloxone blocker that Suboxone does, so you can take it right away. It doesn't matter if you have other opiates in your system or not. I've been on Subutex for years now and when I had my son, the hospital gave me Subutex and Percocet together. You'll be fine, since there's no blocker in Subutex, you won't go into immediate withdrawal or anything. Answered by Sina Bakemeier 4 months ago.


Can subutex be used with other opiates?
Just wondering if subutex blocks the use of other opiates to your sensors the way suboxone does or can it be used in conjunction with other painkillers, pharmaceutical or "other". Does it push other opioids out of your system or is that the main difference between subutex and suboxone? Asked by Eula Slominski 4 months ago.

Hey. As per my answer to your other subutex question, you can't use it with other opiates/opioids. It has absolutely nothing to do with ODing (unless you are trying to break through the Subutex by using copious amounts of dope). If you take an opiate before taking subutex, you will be put in precipitated withdrawals (which sucks more than regular withdrawals). If you take an opiate after taking subutex, the effects of that opiate would be blocked, unless you take an extremely high amount of that opiate (and this is playing russian roulette; at best you would get mild effects, at worst, OD) Buprenorphine (the active ingredient in Subutex) has extremely high affinity for your opiate receptors. It works as a partial agonist. this means, 1) it binds to your receptors (like a key would fit into a keyhole) 2) it activates your receptors 3) it remains stuck to the receptors for a long period of time If you've taken say heroin or morphine, and any morphine is still bound to your receptors, buprenorphine will displace it. This will put you into immediate withdrawal the same way a shot of Narcan would. (3) is the real reason you can't use opiates with buprenorphine. It binds with very high affinity, and it remains stuck to the receptors for a long period of time. Out of all the pharmaceutical opiates on the market, the only one I've seen that has higher affinity than buprenorphine, is diprenorphine (which is used for reversing accidental Immobilon or Wildnil ODs) ------ The issue with Suboxone is this: Subutex contains only Buprenorphine. Suboxone contains both buprenorphine and naloxone (narcan). Naloxone is not absorbed in sufficient amounts when taken sublingually; only IV/IM. So they figured that since naloxone would be active when injected, it would put the user into immediate withdrawal if the tablet was injected. That was the theory. In practice, it does not work out. Answered by Suanne Nicolaysen 4 months ago.

This Site Might Help You. RE: can subutex be used with other opiates? Just wondering if subutex blocks the use of other opiates to your sensors the way suboxone does or can it be used in conjunction with other painkillers, pharmaceutical or "other". Does it push other opioids out of your system or is that the main difference between subutex and suboxone? Answered by China Quates 4 months ago.

The short answer is no. It increases chance of overdose and accidentally inhaling one's own vomit to the degree that it kills the patient. It is important to warn patients of the dangers of misusing benzodiazepines when taking SUBOXONE or SUBUTEX. Overdose deaths have occurred when buprenorphine and benzodiazepines were concomitantly abused via the parenteral route.1-6 On at least one occasion, a buprenorphine overdose has been associated with oral benzodiazepine ingestion.7 Only 2 buprenorphine alone overdose deaths have been reported; in both cases, death was due to Mendelson's syndrome (ie, asphyxiation due to aspirating vomitus).4 Answered by Jason Tomasic 4 months ago.

Can You Shoot Subutex Answered by Eddie Rouzer 4 months ago.

absoluty not Answered by Grant Ingran 4 months ago.


Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
020732/002 SUBUTEX BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 2MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
020732/003 SUBUTEX BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 8MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
018401/001 BUPRENEX BUPRENORPHINE HYDROCHLORIDE INJECTABLE/INJECTION EQ 0.3MG BASE per ML
018410/001 BUPRENEX BUPRENORPHINE HYDROCHLORIDE INJECTABLE/INJECTION 0.3MG
020732/002 SUBUTEX BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 2MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
020732/003 SUBUTEX BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 8MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
074137/001 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE INJECTABLE/INJECTION EQ 0.3MG BASE per ML
076931/001 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE INJECTABLE/INJECTION EQ 0.3MG BASE per ML
078331/001 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE INJECTABLE/INJECTION EQ 0.3MG BASE per ML
078633/001 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 2MG BASE
078633/002 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 8MG BASE
090279/001 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 2MG BASE
090279/002 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 8MG BASE
090360/001 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 2MG BASE
090360/002 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 8MG BASE
090622/001 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 2MG BASE
090622/002 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 8MG BASE
090819/001 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 2MG BASE
090819/002 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 8MG BASE
201066/001 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 2MG BASE
201066/002 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 8MG BASE
201760/001 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 2MG BASE
201760/002 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 8MG BASE
204442/001 PROBUPHINE BUPRENORPHINE HYDROCHLORIDE IMPLANT/IMPLANTATION EQ 80MG BASE per IMPLANT
206586/001 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE INJECTABLE/INJECTION EQ 0.3MG BASE per ML
207276/001 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 2MG BASE
207276/002 BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE TABLET/SUBLINGUAL EQ 8MG BASE
207932/001 BELBUCA BUPRENORPHINE HYDROCHLORIDE FILM/BUCCAL EQ 0.075MG BASE
207932/002 BELBUCA BUPRENORPHINE HYDROCHLORIDE FILM/BUCCAL EQ 0.15MG BASE
207932/003 BELBUCA BUPRENORPHINE HYDROCHLORIDE FILM/BUCCAL EQ 0.3MG BASE
207932/004 BELBUCA BUPRENORPHINE HYDROCHLORIDE FILM/BUCCAL EQ 0.45MG BASE
207932/005 BELBUCA BUPRENORPHINE HYDROCHLORIDE FILM/BUCCAL EQ 0.6MG BASE
207932/006 BELBUCA BUPRENORPHINE HYDROCHLORIDE FILM/BUCCAL EQ 0.75MG BASE
207932/007 BELBUCA BUPRENORPHINE HYDROCHLORIDE FILM/BUCCAL EQ 0.9MG BASE

Manufacturers

Manufacturer name
Indivior UK Limited

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