SIMVASTATIN Ressources

Application Information

This drug has been submitted to the FDA under the reference 021961/001.

Names and composition

"SIMVASTATIN" is the commercial name of a drug composed of SIMVASTATIN.
It belongs to the class Statins and is used in Hyperlipidaemia (Cardiovascular System)

Answered questions

What is the imoprtance of taking simvastatin at evening?
Asked by Carey Axtell 3 months ago.

For simvastatin, the evidence is that marginally better lowering of total and LDL cholesterol comes from taking the tablets in the evening than in the morning. Simvastatin is best taken at night, when concentrations of total cholesterol and low density lipoprotein may be at their greatest. Most manufacturers of statins recommend that they are taken at night because physiological studies show that most cholesterol is synthesised when dietary intake is low. Researchers have found that simvastatin therapy is best taken in the evenings as opposed to in the morning, in order to avoid times when total cholesterol and low-density lipoprotein cholesterol (LDL-C) concentrations are particularly high. "Most manufacturers of statins recommend that they are taken at night, on the basis of physiological studies which show that most cholesterol is synthesized when dietary intake is at its lowest," note Alan Wallace and colleagues. However, "doubt has been cast on whether statins need to be taken at night," the researchers write in the British Medical Journal. To investigate, they randomly assigned 57 adults currently taking 10 or 20 mg of simvastatin each night for primary or secondary prevention of coronary heart disease, stroke, or peripheral vascular disease to dosing in the morning or evening for a period of 8 weeks. Results showed that the switch from evening to morning dosing resulted in statistically significant increases in total cholesterol and LDL-C, although treatment adherence did not differ between the two groups. "Simvastatin is probably best taken at night," the team concludes. "Simvastatin is the most widely prescribed statin in the UK, and this finding has implications for compliance in preventing coronary heart disease." They add that a similar effect may not occur with atorvastatin because this statin has a longer elimination half-life. Take care as always! Answered by Roosevelt Yong 3 months ago.

It is quite important to take simvastatin at night as the production of cholesterol is mainly done at night. The plasma level of simvastatin and it's active metabolite peak 4 hours after taking the dose and then the level rapidly declines to about 10% of the peak after 12 hours post dose. Therefore, it won't be as effective in inhibiting the production of cholesterol if you took the dose in the morning as by the evening only 10% of the peak level is still present. Answered by Penni Nakamori 3 months ago.

Simvastatin has been proven to be more effective at lowering cholesterol levels when taken in the evening as opposed to in the morning. So if you take the medication before bed you will allow it to work at its maximal effect with lowering cholesterol. Our bodies make our own cholesterol and the way these drugs work is by stopping your body’s natural production of cholesterol. It just so happens that our bodies make the most cholesterol when we are sleeping so this is the reason why the drugs are more effective when they are taken before bed. So if you can remember to take your simvastatin in the evening it may be beneficial to take it then. But if you are in a good routine of taking it in the morning and think you may forget more doses if you tried switching to the evening I would continue the routine of taking it in the morning. Answered by Bettyann Ingold 3 months ago.


I'm a man 53, living a very healthy life but my LDL cholesterol remain high (180). Is taking Simvastatin good?
I eat no fat, I'm half vegetarian, no drinks/alcohol/cigarette, workouts 3-5x per week. My doctor said that my high LDL is due to heredity in my own metabolism system. He suggests I take Simvastatine once every 3 months, each time is 10mg x 30 days. Some friends told me once I take Simvastatine I will depend on... Asked by Lulu Azim 3 months ago.

I eat no fat, I'm half vegetarian, no drinks/alcohol/cigarette, workouts 3-5x per week. My doctor said that my high LDL is due to heredity in my own metabolism system. He suggests I take Simvastatine once every 3 months, each time is 10mg x 30 days. Some friends told me once I take Simvastatine I will depend on it for the rest of my life. Is it true? Is there other options without taking prolonged medicines? Thank you Answered by Racquel Bartnik 3 months ago.

Asatru, Norse Heathen. Lets divide this question in two: How has it helped me lead a happy life: By not being a pawn, not being a sucker, learning that bad things that happen create two options: buckle under and go all woe is me and hang myself, or pick myself up, dust myself off, and go out and kick @$$. I'm a lot happier not wallowing in self pity. A Healthy life: I prefer to take a more naturalist approach to health. Unlike most modern medicine, "if you have something wrong, lets mask it" .... I prefer to find out WHY something is wrong. Why do i have heartburn? Well, instead of eating the same damn foods, find out which it is that is giving it to me, and STOP EATING IT. As part of my religious practices, I also an amateur herbalist. Enough to know how to heal cuts nearly overnight, make my own alcohol extracts (YAY EVERLCEAR!) and how to cure a massive hangover, as well making digestive aids and relaxation teas. It also means I absolutely refuse to take any prescription or over the counter drug. My liver has a fun enough time dealing with the whisky I shove down my throat, it doesn't need mercury and other heavy metals polluting it as well. However, I am also a living contradiction, and smoke regularly. I guess another reason I don't take prescription drugs. I do enough damage on my own! Answered by Lore Kosanovic 3 months ago.

Stains will reduce your cholesterol. Reducing cholesterol may reduce your risk of heart disease. Ask you rdoctor how much the risk is reduced. Don't accept a percentage. If statins reduce heart disease from 2 in a millioin to 1 in a million, that's a 50% reduction. Big deal. Statins cost a lot and have nasty side effects. They are just not worth it. Besides the whole cholesterol scare is a myth. Do some research. Answered by Desire Donne 3 months ago.

Hi i found a web site on natural cholesterol control supplement Answered by Saran Bouchey 3 months ago.


Can simvastatin make you gain weight?
Asked by Celina Rase 3 months ago.

U.S. BRAND NAMES — Zocor® CANADIAN BRAND NAMES — Apo-Simvastatin®; CO Simvastatin; Dom-Simvastatin; Gen-Simvastatin; Novo-Simvastatin; Nu-Simvastatin; PHL-Simvastatin; PMS-Simvastatin; ratio-Simvastatin; Riva-Simvastatin; Sandoz-Simvastatin; Taro-Simvastatin; Zocor® MEXICAN BRAND NAMES — Colesken; Pusarat; Simlo; Simplaqor; Tulip; Zeid; Zocor; Zorced PHARMACOLOGIC CATEGORY Antilipemic Agent, HMG-CoA Reductase Inhibitor REASONS NOT TO TAKE THIS MEDICINE If you have an allergy to simvastatin or any other part of this medicine. Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved. If you have active liver disease or an increase in liver enzymes. If you are pregnant or may be pregnant. If you are breast-feeding. What is this medicine used for? This medicine is used to slow the progress of heart disease. This medicine is used to lower cholesterol and other harmful types of cholesterol in the body. Good cholesterol (HDL) levels increase. This medicine is used to decrease triglycerides. How does it work? Simvastatin reduces cholesterol production. How is it best taken? Take this medicine in the evening. Take this medicine with or without food. Take with food if it causes an upset stomach. Follow diet plan and exercise program as recommended by healthcare provider. What do I do if I miss a dose? (does not apply to patients in the hospital) Take a missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and return to your regular schedule. Do not take a double dose or extra doses. Do not change dose or stop medicine. Talk with healthcare provider. What are the precautions when taking this medicine? If you have kidney disease, talk with healthcare provider. Check medicines with healthcare provider. This medicine may not mix well with other medicines. Do not take colestipol or cholestyramine within 4 hours of this medicine. Avoid use with clarithromycin, cyclosporine, danazol, erythromycin, HIV protease inhibitors, itraconazole, ketoconazole, nefazodone, or telithromycin. Avoid or limit alcohol intake (includes wine, beer, and liquor) to less than 3 drinks a day. Drinking too much alcohol may increase the risk of liver disease. Avoid grapefruit and grapefruit juice. You can get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen; wear protective clothing and eyewear. Use birth control that you can trust to prevent pregnancy while taking this medicine. What are some possible side effects of this medicine? Headache. Belly pain. Diarrhea. Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative. Muscle weakness. Joint pain. What should I monitor? Change in condition being treated. Is it better, worse, or about the same? Check blood work (cholesterol panel, liver function). Talk with healthcare provider. Follow up with healthcare provider. REASONS TO CALL HEALTHCARE PROVIDER IMMEDIATELY If you suspect an overdose, call your local poison control center or emergency department immediately. Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat. Severe muscle pain or weakness. Flu-like symptoms. Unusual bruising or bleeding. Yellow skin or eyes. Any rash. No improvement in condition or feeling worse. How should I store this medicine? Store at room temperature. Protect from moisture. Do not store in a bathroom or kitchen. GENERAL STATEMENTS If you have a life-threatening allergy, wear allergy identification at all times. Do not share your medicine with others and do not take anyone else's medicine. Keep all medicine out of the reach of children and pets. Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant). Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins. Answered by Larhonda Coolbaugh 3 months ago.

What I had to do was start eating 4 meals a day, and snacking in between. I would have breakfast then go to school. In second class I had my teacher lest us eat so I would have a couple fruit cups or some yogurt or nuts or something, then have lunch, then last class my teacher lets us eat so I have another snack of whatever I didn't eat at lunch. Then after school I would eat until I was stuffed. Like I'd eat a LOT of food. Then a few hours later I would have dinner. Then after dinner if snack again. I find it's not really the food I eat that helps me gain weight, it's how much food I eat and how often I eat. I gained ten pounds in half a year doing this :P Answered by Kourtney Wojnicki 3 months ago.


Simvastatin by aurob 20mg tablet?
Asked by Tomika Vopava 3 months ago.

Simvastatin is used together with lifestyle changes (diet, weight-loss, exercise) to reduce the amount of cholesterol (a fat-like substance) and other fatty substances in your blood. Simvastatin is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body. Buildup of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats may help to decrease your risk of heart disease, angina (chest pain), strokes, and heart attacks. In addition to taking a cholesterol-lowering medication, making certain changes in your daily habits can also lower your cholesterol blood levels. You should eat a diet that is low in saturated fat and cholesterol, exercise 30 minutes on most, if not all days, and lose weight if you are overweight. Answered by Orlando Sickafoose 3 months ago.


Does the drug Simvastatin work quickly? How soon can I feel results in energy?
Addendum: I am expecting to start the drug Simvastatin. But how soon before I feel results? Asked by Delena Lomboy 3 months ago.

Simvastatin is designed to lower cholesterol, nothing more. You won't fee anything as it's working. Ignore the first answer. They'd have you believe that statins are the devil's brew, causing all sorts of nasty side effects. I've been on high dose simvastatin / niacin for YEARS, including grad school. As for affecting the brain, yea, right. Feel free to ask my patients or colleagues. Answered by Abbey Powskey 3 months ago.

You're kidding right? Simvastatin isn't some kind of energy drug. If anything, it will lower your energy level, make you depressed, make your joints ache, kill your brain cells, and lower your overall immune system. If you don't change your diet, it has no effect on your cholesterol. You are better off taking a low dose aspirin tablet each day. It has fewer side effects. Taking a pharmaceutical grade molecularly distilled omega-3 DHA supplement is much better than a statin or aspirin. At least an omega-3 supplement will improve your good cardio-protective HDL cholesterol levels and actually treat the main cause of high cholesterol... an omega-3 fatty acid deficiency. Diets that cause an omega-3 fatty acid deficiency always produce an increase in total serum cholesterol levels and increase ones risk for coronary artery disease. You are much better off treating your omega-3 fatty acid deficiency than risking your health with any statin drug. By the way, thanks to the food industry ninety-nine percent of Americans are severely deficient in omega-3 fatty acids. It has been estimated that 96,000 Americans died from this deficiency last year alone. This deficiency also often results in sudden cardiac death. Answered by Viki Forsman 3 months ago.


Which are side effects of simvastatin ?
i want to know more details abou simvastatin side effects. Asked by Laila Clabo 3 months ago.

Simvastatin Side Effects Many drugs offer side effects including Simvastin for treating cholesterol which are simply hard to avoid. In rare conditions, Simvastin may lead to such conditions that may turn into collapsing skeletal muscle tissue, which may eventually lead to kidney failure. The common symptoms are unexplained muscle pain, tenderness, muscle weakness, fever or flue symptoms and dark-colored urine. Answered by Chantal Guterrez 3 months ago.

Hello, My nursing has included six years in cardiology. I've never heard of those side effects being attributed to Zocor (Simvastatin). Your mother-in-law should resume taking it. If she's concerned about it. She should listen to her Doctor, not a well-intentioned (but misinformed) friend. The greatest concern w/Zocor, & many other meds, is elevated liver enzymes, & BUN/Crtn levels. These are screened for w/periodic blood work. If the numbers do start to go up. The regimen is adjusted. No problem. The other concern has been greatly overblown by laymen: Rhabdomyolysis. That results in the break-down of muscle tissue within the body. It's very serious, & very rare. Once people hear about it. They're obviously scared. Suddenly, every little muscle cramp & ache becomes a harbinger of doom. If Rhabdomyolysis were to occur. The muscles affected would be the large skeletal muscles, the thighs or ribs. If muscle cramping occurs here. Patients are asked to stop the med for two weeks. If the pain goes away, another med may be in order. The problem w/this, is many muscle strains also resolve in two weeks' time. It boils down to trusting your Doctor. You either do, or you don't. If you don't? Move on. You're wasting your time w/your current Doc. Be Well. Answered by Lashandra Whisenand 3 months ago.

Simvastatin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: * constipation * stomach pain * nausea * headache Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately. If you experience any of the first 3 symptoms on this list, do not take any more simvastatin without talking to your doctor: * muscle pain, tenderness, or weakness * dark red urine * lack of energy, tiredness, or weakness * fever * fever or chills * flushing * blisters * rash * hives * itching * swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs * difficulty breathing or swallowing * hoarseness * joint pain * sensitivity to light Answered by France Lanham 3 months ago.

dizzyness, skin rashes, nausia ect. Answered by Tracee Andaverde 3 months ago.


How Does CoQ10 Levels Deplete? Does Taking a simvastatin (Zocor) Affect levels of CoQ10?
Last week my docotor said I had high cholesterol. I'm only a 20-year old male. However, I'm overweight at 220 pounds and 5'7. Over the past year or two, I haven't been eating healthy. So I personally attribute my high cholesterol levels to my inactvity + poor diet. My docotor came back with my blood results and... Asked by Annamae Ammerman 3 months ago.

Last week my docotor said I had high cholesterol. I'm only a 20-year old male. However, I'm overweight at 220 pounds and 5'7. Over the past year or two, I haven't been eating healthy. So I personally attribute my high cholesterol levels to my inactvity + poor diet. My docotor came back with my blood results and prescribed Zocor ( a simvastatin) to help lower my bad cholesterol levels. I'm supposed to take 40 MG pill daily of this. I took my first pill tonight of 40MG. Doing some further research online, I've found some discomforting information regarding the 'statin' family of drugs. I'm paticullary worried about the depletion of CoQ10 levels, which have been shown to have beneficial effects themselves. After all my research, I've decided I'm not going to go on the meds and just try the more "natural" route and just eat healthier and exercise. My biggest concern is this: Will the Pill I took of 40MG affect my levels at all? If so, will the levels return to 'normal' considering I'm 100% discontinuing this drug? I'll wait until more information comes out on this drug. Until then, I don't feel safe doing so. Answered by Phoebe Tomkus 3 months ago.

Simvastatin has been around for many years. While any statin has been shown to lower CoQ10 levels, it's interesting that a couple of studies (Sorry, but I don't have the reference handy) have shown that supplementing patients with CoQ10 has no effect on the rate of side effects. There's a lot of unscientific sites out there (spacedoc.net for one) that rail about the dangers of statins. Given the millions of statin scripts filled annually, there should be a lot more people stopping the drugs if they were as dangerous as some claim. I've been on high dose simvastatin & niacin for YEARS. No side effects. No muscle weakness, no liver damage, no cognitive changes. Nada. Answered by Jack Sjoquist 3 months ago.

Congratulations, you are smarter than 70% of the people on this board and 95% of doctors. Depletion of CoQ10 is the best known side effect of statins. Their effect on CoQ10 is reversible but the effect of low CoQ10 may not be. (If you only took one pill, you are being paranoid) There is a DNA mutation in the midocodria of your muscles. Mutations do not reverse. Do some studying what a natural route might be. It is not what you think. Actually if you do the low fat low cholesterol diet, you will NEVER lower your numbers. You will need to accept that your levels do not need to be as low as your doctor thinks. If you get your total below 250 with a good ratio of HDL to total, you will be fine. If you go on a low carb, high saturated fat, whole foods diet, you will lose weight, increase your HDL, prevent type 2 diabetes, and live longer. Pharmacist who's life was almost ruined by Lipitor Answered by Billie Skea 3 months ago.

Coenzyme CoQ10 shares a biosynthetic pathway with cholesterol. The synthesis of an intermediary precursor of coenzyme Q10, mevalonate, is inhibited by some beta blockers, blood pressure-lowering medication, and statins, a class of cholesterol-lowering drugs. Since my cardiac operation I'm on Warfarin, Rampiril, Bisoprolol Beta-blockers, Simvastin, and Omeprazole, which prevents my taking Aspirin and Q10 products. I would imagine they would be of benefit to anyone with a good heart though. So many beneficial claims are made for the product. Answered by Selene Schmeider 3 months ago.


What are the side effects of Simvastatin 40mg does it help lower cholesterol?
Asked by Catheryn Robbert 3 months ago.

Simvastatin 40mgs is the standard dose of the standardly chosen statin used to lower cholesterol in the UK. Most patients tolerate it well, but like all drugs it can have side effects. Blood and lymphatic system disorders: Rare: anaemia Nervous system disorders: Rare: headache, paresthesia, dizziness, peripheral neuropathy Gastrointestinal disorders: Rare: constipation, abdominal pain, flatulence, dyspepsia, diarrhoea, nausea, vomiting, pancreatitis Hepato-biliary disorders: Rare: hepatitis/jaundice Very rare: hepatic failure Skin and subcutaneous tissue disorders: Rare: rash, pruritus, alopecia Musculoskeletal, connective tissue and bone disorders: Rare: myopathy, rhabdomyolysis (see section 4.4), myalgia, muscle cramps General disorders and administration site conditions: Rare: asthenia An apparent hypersensitivity syndrome has been reported rarely which has included some of the following features: angioedema, lupus-like syndrome, polymyalgia rheumatica, dermatomyositis, vasculitis, thrombocytopenia, eosinophilia, ESR increased, arthritis and arthralgia, urticaria, photosensitivity, fever, flushing, dyspnoea and malaise. Answered by Keisha Cleveland 3 months ago.

This Site Might Help You. RE: What are the side effects of Simvastatin 40mg does it help lower cholesterol? Answered by Annette Poitevint 3 months ago.

Side Effects Of Simvastatin 40 Mg Answered by Marianela Asel 3 months ago.

Simvastatin 40 Mg Side Effects Answered by Irmgard Whitcraft 3 months ago.

It lowers cholesterol but why do you want to lower your cholesterol. High cholesterol is not a disease, Mine is 320 and I would not consider trying to lower it. Especially with statins. The side effects are damaged liver, muscle pain, and memory loss. They are also quite expensive. Answered by Catherin Laehn 3 months ago.

My Dr. has me take simvastatin at night and the only side-effect I've noticed so far is that the next day I'm not hungry until around 2 or 3 in the afternoon. I used to get hungry around 10 in the morning but I don't anymore. I don't know if it works yet, however. I need to go in for blood tests next month. Answered by Mabel Durough 3 months ago.

Simvastatin is used together with lifestyle changes (diet, weight-loss, exercise) to reduce the amount of cholesterol (a fat-like substance) and other fatty substances in your blood. Simvastatin is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body. Buildup of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats may help to decrease your risk of heart disease, angina (chest pain), strokes, and heart attacks. In addition to taking a cholesterol-lowering medication, making certain changes in your daily habits can also lower your cholesterol blood levels. You should eat a diet that is low in saturated fat and cholesterol, exercise 30 minutes on most, if not all days, and lose weight if you are overweight. Simvastatin may cause side effects. Tell your doctor if this symptom is severe or does not go away: * constipation If you experience the following symptoms, call your doctor immediately: * muscle pain, tenderness, or weakness * lack of energy * fever * yellowing of the skin or eyes * pain in the upper right part of the stomach * nausea * extreme tiredness * unusual bleeding or bruising * loss of appetite * flu-like symptoms * rash * hives * itching * difficulty breathing or swallowing * swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs * hoarseness Answered by Tarsha Olarte 3 months ago.


Is anyone taking Simvastatin and having side effects? It is the generic form of Evista for cholesterol. ?
I am very sore in the lower back and stomach and it hurts to breathe. I am wondering if it is from this pill. Asked by Bryanna Callabrass 3 months ago.

Yes- I have taken Simvastatin daily and regularly for 4 years for my cardiac and Cholesterol problems. I too have noticed back pain, body pain and pain in the leg joints. On reporting this he has changed the medication and given Storvas - another Vastatin group (Atovastin Calcium tablets) medicine but the problem continues. If you have more of the pain it is better you consult your doctor and let him give some alternate medication. However please note the side effects of Simvastatin as under and report if it is severe. Side effects that you should report to your doctor or health care professional as soon as possible: • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue • dark urine • fever • joint pain • muscle cramps, pain • redness, blistering, peeling or loosening of the skin, including inside the mouth • trouble passing urine or change in the amount of urine • unusually weak or tired • yellowing of the eyes or skin Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): • constipation • heartburn • stomach gas, pain, upset - Answered by Bert Mcguinness 3 months ago.

Simvastatin is used together with lifestyle changes (diet, weight-loss, exercise) to reduce the amount of cholesterol (a fat-like substance) and other fatty substances in your blood. Simvastatin is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body. Buildup of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats may help to decrease your risk of heart disease, angina (chest pain), strokes, and heart attacks. In addition to taking a cholesterol-lowering medication, making certain changes in your daily habits can also lower your cholesterol blood levels. You should eat a diet that is low in saturated fat and cholesterol, exercise 30 minutes on most, if not all days, and lose weight if you are overweight. Simvastatin may cause side effects. Tell your doctor if this symptom is severe or does not go away: * constipation If you experience the following symptoms, call your doctor immediately: * muscle pain, tenderness, or weakness * lack of energy * fever * yellowing of the skin or eyes * pain in the upper right part of the stomach * nausea * extreme tiredness * unusual bleeding or bruising * loss of appetite * flu-like symptoms * rash * hives * itching * difficulty breathing or swallowing * swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs * hoarseness Raloxifene is used to prevent and treat osteoporosis (condition in which the bones become thin and weak and break easily) in women who have undergone menopause (change of life; end of menstrual periods). Raloxifene is also used to decrease the risk of developing invasive breast cancer (breast cancer that has spread outside of the milk ducts or lobules into the surrounding breast tissue) in women who are at high risk of developing this type of cancer or who have osteoporosis. Raloxifene cannot be used to treat invasive breast cancer or to prevent invasive breast cancer from coming back in women who have already had the condition. Raloxifene also cannot be used to decrease the risk of developing non-invasive breast cancer. Raloxifene is in a class of medications called selective estrogen receptor modulators (SERMs). Raloxifene prevents and treats osteoporosis by mimicking the effects of estrogen (a female hormone produced by the body) to increase the density (thickness) of bone. Raloxifene decreases the risk of developing invasive breast cancer by blocking the effects of estrogen on breast tissue. This may stop the development of tumors that need estrogen to grow. Raloxifene may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: * hot flashes (more common in the first 6 months of raloxifene therapy) * leg cramps * swelling of the hands, feet, ankles, or lower legs * flu-like syndrome * joint pain * sweating * difficulty falling asleep or staying asleep Some side effects can be serious. If you experience any of the symptoms mentioned in the IMPORTANT WARNING section, call your doctor immediately. Raloxifene may cause other side effects. Call your doctor if you experience any unusual symptoms while you are taking this medication. Please see the web pages for more details on Simvastatin and Raloxifene (generic name) Evista (brand name). Consult your doctor. Answered by Gabriele Naidu 3 months ago.


What are all the uses for simvastatin?
Asked by Glennie Shimer 3 months ago.

Simvastatin is a HMG-CoA Reductase Inhibitor otherwise known as a "statin". It is used to treat high cholesterol. In some cases even if the cholesterol is not that high it will be used to reduce mortality and serious heart problems in high risk people ( people with heart disease, diabetes, vascular disease, history of stroke). There are no other uses. Answered by Dorinda Cossell 3 months ago.


Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
021961/001 SIMVASTATIN SIMVASTATIN TABLET, ORALLY DISINTEGRATING/ORAL 10MG
021961/002 SIMVASTATIN SIMVASTATIN TABLET, ORALLY DISINTEGRATING/ORAL 20MG
021961/003 SIMVASTATIN SIMVASTATIN TABLET, ORALLY DISINTEGRATING/ORAL 40MG
021961/004 SIMVASTATIN SIMVASTATIN TABLET, ORALLY DISINTEGRATING/ORAL 80MG
076052/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
076052/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
076052/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
076052/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
076052/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
076285/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
076285/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
076285/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
076285/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
076285/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
076532/001 SIMVASTATIN SIMVASTATIN TABLET/ ORAL 5MG
076532/002 SIMVASTATIN SIMVASTATIN TABLET/ ORAL 10MG
076532/003 SIMVASTATIN SIMVASTATIN TABLET/ ORAL 20MG
076532/004 SIMVASTATIN SIMVASTATIN TABLET/ ORAL 40MG
076532/005 SIMVASTATIN SIMVASTATIN TABLET/ ORAL 80MG
076685/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
076685/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
076685/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
076685/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
076685/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
077691/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
077691/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
077691/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
077691/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
077691/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
077752/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
077752/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
077752/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
077752/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
077752/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
077766/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
077766/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
077766/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
077766/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
077766/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
077837/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
077837/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
077837/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
077837/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
077837/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
078034/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
078034/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
078034/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
078034/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
078034/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
078103/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
078103/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
078103/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
078103/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
078103/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
078155/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
078155/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
078155/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
078155/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
078155/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
078735/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
078735/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
078735/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
078735/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
078735/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
090383/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
090383/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
090383/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
090383/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
090383/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
090868/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
090868/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
090868/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
090868/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
090868/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
200895/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
200895/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
200895/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
200895/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
200895/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
206679/001 SIMVASTATIN SIMVASTATIN SUSPENSION/ORAL 20MG per 5ML
206679/002 SIMVASTATIN SIMVASTATIN SUSPENSION/ORAL 40MG per 5ML

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
019766/001 ZOCOR SIMVASTATIN TABLET/ORAL 5MG
019766/002 ZOCOR SIMVASTATIN TABLET/ORAL 10MG
019766/003 ZOCOR SIMVASTATIN TABLET/ORAL 20MG
019766/004 ZOCOR SIMVASTATIN TABLET/ORAL 40MG
019766/005 ZOCOR SIMVASTATIN TABLET/ORAL 80MG
021961/001 SIMVASTATIN SIMVASTATIN TABLET, ORALLY DISINTEGRATING/ORAL 10MG
021961/002 SIMVASTATIN SIMVASTATIN TABLET, ORALLY DISINTEGRATING/ORAL 20MG
021961/003 SIMVASTATIN SIMVASTATIN TABLET, ORALLY DISINTEGRATING/ORAL 40MG
021961/004 SIMVASTATIN SIMVASTATIN TABLET, ORALLY DISINTEGRATING/ORAL 80MG
076052/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
076052/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
076052/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
076052/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
076052/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
076285/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
076285/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
076285/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
076285/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
076285/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
076532/001 SIMVASTATIN SIMVASTATIN TABLET/ ORAL 5MG
076532/002 SIMVASTATIN SIMVASTATIN TABLET/ ORAL 10MG
076532/003 SIMVASTATIN SIMVASTATIN TABLET/ ORAL 20MG
076532/004 SIMVASTATIN SIMVASTATIN TABLET/ ORAL 40MG
076532/005 SIMVASTATIN SIMVASTATIN TABLET/ ORAL 80MG
076685/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
076685/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
076685/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
076685/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
076685/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
077691/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
077691/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
077691/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
077691/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
077691/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
077752/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
077752/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
077752/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
077752/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
077752/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
077766/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
077766/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
077766/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
077766/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
077766/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
077837/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
077837/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
077837/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
077837/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
077837/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
078034/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
078034/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
078034/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
078034/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
078034/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
078103/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
078103/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
078103/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
078103/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
078103/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
078155/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
078155/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
078155/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
078155/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
078155/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
078735/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
078735/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
078735/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
078735/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
078735/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
090383/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
090383/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
090383/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
090383/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
090383/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
090868/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
090868/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
090868/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
090868/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
090868/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
200895/001 SIMVASTATIN SIMVASTATIN TABLET/ORAL 5MG
200895/002 SIMVASTATIN SIMVASTATIN TABLET/ORAL 10MG
200895/003 SIMVASTATIN SIMVASTATIN TABLET/ORAL 20MG
200895/004 SIMVASTATIN SIMVASTATIN TABLET/ORAL 40MG
200895/005 SIMVASTATIN SIMVASTATIN TABLET/ORAL 80MG
206679/001 SIMVASTATIN SIMVASTATIN SUSPENSION/ORAL 20MG per 5ML
206679/002 SIMVASTATIN SIMVASTATIN SUSPENSION/ORAL 40MG per 5ML

Manufacturers

Manufacturer name
Discovery Pharmaceuticals
Merck Sharp & Dohme Ltd

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