REBETOL Ressources

Application Information

This drug has been submitted to the FDA under the reference 020903/001.

Names and composition

"REBETOL" is the commercial name of a drug composed of RIBAVIRIN.
It belongs to the class Hepatitis B and hepatitis C treatments and is used in Viral infections (Infections and Infestations)

Answered questions

Are rebetol and pegintron forms of chemotherapthy?
my dad has hep c. and was taking rebetol/pegintron combo injections and he keeps refering to it as his chemotherapy. but nothing i've read about it says its a cancer treatment. he keeps telling me he has cancer. and that it is his cancer treatment. Asked by Signe Shockley 4 months ago.

These are not chemotherapy for cancer, but rather for hepa C: PEG-Intron, peginterferon alfa-2b, is indicated for use alone or in combination with REBETOL (ribavirin, USP) for the treatment of chronic hepatitis C in patients with compensated liver disease who have not been previously treated with interferon alpha and are at least 18 years of age. REBETOL (ribavirin, USP) Capsules and Oral Solution are indicated in combination with INTRON A (interferon alfa-2b, recombinant) Injection for the treatment of chronic hepatitis C in patients 18 years of age and older with compensated liver disease previously untreated with alpha interferon and in patients 18 years of age and older who have relapsed following alpha interferon therapy. Hepatitis C: * Chronic infection: 55%-85% of infected persons * Chronic liver disease: 70% of chronically infected persons * Deaths from chronic liver disease: 1%-5% of infected persons may die * Leading indication for liver transplant Answered by Alissa Serles 4 months ago.

Rebetrol and PEG-intron are the standard treatment fot hepatitis C. Some people like to use different nomenclature because it makes them feel better. Interferon is sometimes used for cancer and other diseases. But by and large, chemotherapy is reserved for cancer treatments. Hepatitis C also causes hepatomas (liver cancer) and he may be suffering from that. Answered by Meagan Michaud 4 months ago.


Has anyone in here gone through the Hepatitis C treatment {Pegasys & Rebetol}? Please share experiences.?
I'm genotype 3a; my HCV PCR quantitative came back at 378,000 two weeks ago. Asked by Denese Dagel 4 months ago.

I'd like to know about how you felt, if you completed treatment and, if so, was the virus eradicated. I was diagnosed with Hepatitis C infection {genotype 3} in 2003 but have been postponing treatment. I've heard horror stories about the side effects of treatment. The vast majority of those whom I've asked stopped the treatment due to the side effects. A few ones completed it but were not cured {they are all genotype 1}. Any honest answers will be welcome. Answered by Gwendolyn Lob 4 months ago.

I did the Pegasys & Rebetol treatment in 2003 - fortunately for you, you only have to do the 24 week tx, I had to do the 48 (I was genotype 1b). It wasn't bad like you read in most people's stories. Do what Stephanie said about drinking lots of water and get an antidepressant. Also I would like to add that you make an effort to get into shape by walking or running a mile a day before starting treatment and keep the exercise going as long as you can while on treatment. I did this and hardly had any of the side effects mentioned by many people on the treatment. Still clear of the virus five years later. You should do fine... Answered by Dorcas Movlin 4 months ago.

Those horror stories are very few and far and inbetween...usually when one has a horrible time on treatment, they ususally have other diseases either brought on by decades of infection with hcv or have other diseases that contradict treatment. Prescreening for possible issues that are contradicted are usually tested for prior to treatment. You don't feel great on treatment at all times, but you dont feel horrible either....The worse are flu like symptoms between 5 and 48 hours after injection....this is why you do your injection when you have a few days off for resting. Things that will get you through treatment? Staying positive, join support groups, online or in person....learn what you can about hcv and it's treatment. Drink LOTS of water, take an antidepressant and anti anxiety ie, like zoloft and buspar.....eat when you can and take it easy. I did 48 weeks 7 years ago and it was the BEST thing that happened since I was very young!!! I now go and go and go.....I no longer have depression- years of antidepressants.... Treatment is doable...it's not horrible.....best of luck!!! Answered by Lizabeth Rygiewicz 4 months ago.


I need professional advice about being on rebetol only 3 months ago and now could be pregnant?
I have been off of interferon/rebetol for 3 months and only did the treatment for 2 and a half months.Is that long enough to do the damage most doctors say it will to an unborn baby?Very scared now I could be putting an unborn childs life at risk.Please only reply if you are aware of HCV and treatment for it ,and... Asked by Caleb Roscorla 4 months ago.

I have been off of interferon/rebetol for 3 months and only did the treatment for 2 and a half months.Is that long enough to do the damage most doctors say it will to an unborn baby?Very scared now I could be putting an unborn childs life at risk.Please only reply if you are aware of HCV and treatment for it ,and the effects to the baby.I do know they say wait 6 months after completing treatment but since I only did 2 1/2 months and stopped whats the chances here. Answered by Maren Roddey 4 months ago.

You also know that one of the warnings with use of Rebetron is to use two methods of contraception to avoid pregancy. Okay, enough lecture. There is a chance for birth defects but how big a chance I don't know. Significant defects have been seen in lab mice with just 1/20th of the human dosage. And you're still within the 6 month period. First determine whether you're actually pregnant. If you're not, this discussion is over and be sure to use 2 forms of contraception. But if you are, this is something you need to discuss with your OB/Gyn inmmediately. You'd require close monitoring. You might have to face a difficult decision further down the road. Answered by Joni Gartman 4 months ago.

if you only did 2 and a 1/2 months worth of antiviral chemotherapy, it's real iffy. the reason is it usually takes your treatment time to rid the body of the medications. had you waited to become pregnant for at least 8 months you might of been out of the woods. my suggestion to you is talk to your obgyn and liver specialist. i would continue to drink water at this point as if you were on antiviral chemotherapy, this will clear the meds out over time. i would give you a 40% chance of it not harming the baby, but until i know exactly how far along you are, i can't guarentee a correct answer..... i did a 48 weeks of antiviral chemotherapy and although i cannot get pregnant anymore, i certainly felt as though 6 months was not long enough to rid the mediction. it took me a good year to feel half way healthy and another year to feel 95%. the medication is very dangerous and toxic. i wish i could give you a positive...... Answered by Caitlyn Reddig 4 months ago.


Coping with Pegylated Interferon and Rebetol,,,?
Please suggests coping ideas for arthritis of the hips, spine and knees,,, Have been experiencing a considerable amount of pain,,and being a supervisor where I am employed do not wish to take any time off work due to an inconvenience,,,, Have notified the Hepatologist about the pain and am awaiting to hear... Asked by Karyl Ohmer 4 months ago.

Please suggests coping ideas for arthritis of the hips, spine and knees,,, Have been experiencing a considerable amount of pain,,and being a supervisor where I am employed do not wish to take any time off work due to an inconvenience,,,, Have notified the Hepatologist about the pain and am awaiting to hear back,,do not necessarily want a prescription medication,,,and do walk on my treadmill and have use of an exercise bike both in my home to help loosen up joints and muscles before work,,, Any ideas are appreciated,,, And if you dont know what interferon and its agents are, please dont try to answer this question,,,, Consuming 110-130 ounces of water a day to compensate for the two cups of coffee I drink in the morning,,, Answered by Mariam Indeck 4 months ago.

Hi Arnie! :o) It's Stephanie! Congrad's on being on treatment! How long has it been since you began? Also, did they test you for lyme disease or rhuematoid arthritis before you began? If so, how were the results? You have to remember that sometimes interferoncan make pre-existing (whether known or unknown) worse. Your doing great by drinking water. Have you asked your doctor about maybe adding a suppliment to help the joints and bones? Sometimes with antiviral chemotherapy if your doing too much that can also contribute to pain and stiffness in joints. You might be overdoing it with the exersize bike and treadmill, walking around the block might be a better idea....it is more natural. Sounds like to me you just might be over-doing it. You should rest as much as you can as you are already working- which uses much energy. If you feel you need to get exersize, low impact is your best option...walking, swimming.....but don't over do it! :o) Answered by Halina Fitzerald 4 months ago.


What can I do for a rash on my body from the Medicine Rebetol?
Im just started the combination therapy for hep. C interferon with rebetol and I have a rash all over my body that stings and burns and i was wondering if anyone knew what I could use to help it out?? Asked by Miki Kunkler 4 months ago.

You can try applying something like hydrocortisone cream (an example only) to the aera to try and help with any itching. However, I would recommend checking with your doctor first before trying it to see what they say. Answered by Marni Tramontano 4 months ago.


I had a blood work this morning and...?
First I am in rebetol and pegintron, treatment for hepatitis c for 4 months already, and I am undetectable now. Well the question I have the nurses didn't know how to answer, This morning I had my blood work and my blood didn't want to come out, finally it did after a long time but it took almost drop by... Asked by Denver Barahana 4 months ago.

First I am in rebetol and pegintron, treatment for hepatitis c for 4 months already, and I am undetectable now. Well the question I have the nurses didn't know how to answer, This morning I had my blood work and my blood didn't want to come out, finally it did after a long time but it took almost drop by drop, so long to fill up the tube! I have good veins, this have never happend before, please help me to answer this question because after my blood work I don't feel good. I am not a nervous person or anything like that ok. Answered by Kali Greenly 4 months ago.

As a nurse who does blood draws and starts IVs, I can tell you that this sometimes happens. The stick may not have been good as usual. The tourniquet may have been applied too tightly this time. A failure to see blood flow or seeing slow flow can indicate a defective Vacutainer or the needle may not have been completely in the vein. If this never again happens, chalk it up to one of the reasons I gave you. Answered by Shawna Sewyerd 4 months ago.

"I am undetectable now" Ha! That's what YOU think! I just detected you by the fact you posted this question, and I'd bet my next 3 paychecks that several people have detected you today, either by seeing you or by hearing you. Answered by Selma Vandivier 4 months ago.


Does anyone know of a way to get there hepatitis c medicine cheaper?
I have to take peg-intron and rebetol medicine for my hepatitis. After my insurance i am still going to have to pay over $2000 for one month of medication. Was wondering if anyone knew of something else to do? Asked by Hermine Gladue 4 months ago.

You will need to contact Roche's Pegassist 1-877-734-2797 or Schering-Plough's Commitment to Care 1-800-521-7157. They go by income and you will have to download a form and get your doctor to sign it, then give them some info from your tax return. Many of the people in our support group get free meds. Good luck. Answered by Jesenia Pearse 4 months ago.

I have asthma and my meds are horrible in price. I have started getting mine from Canada druggists for way cheaper. If you want to message me off Answers tomorrow I can get you the link that I use. It's in my office, though, and I'm at home. Drugs are EXACTLY the same, packaged a little different, but MUCH cheaper. Answered by Doris Barncastle 4 months ago.

I am in advanced stages of c and need the medicine interferon or whatever they give you scared for mym lfe and cant find anbody to help cause im just some f**king junkie. so if you find any way tell you should be able to get me a message through answers.Please. Answered by Stevie Louchen 4 months ago.

I take alot of medication and even with my insurance the co-pay each month is still alot of money so I started going through medco and getting a 3 month supplie for the same cost of one month it saves us alot of money Answered by Angella Courtwright 4 months ago.

homeopathy. cured my dad and best friend. ;) Answered by Santa Strictland 4 months ago.


How long a person with compensated cirrhosis of the liver can live?
i'VE BEEN DIAGDOSED WITH CHRONIC HEPATITIS C AND COMPENSATED CIRRHOSIS OF THE LIVER I AM A MALE 31 Y/O . TREATMENT FOR HEP C DID NOT WORK FOR ME (( PEGINTRON , REBETOL ) Asked by Joelle Lakhani 4 months ago.

I'm sorry that treatment did not work for you. It all depends on how aggressive your hep C might be in it's attack on your liver. Your doctor that treated you for the hep C might be able to give you a time frame on how long it might take. Are you being considered for transplant yet? Cirrhosis has 3 stages- A is compensated cirrhosis. B is the beginning of decompensation where you need medications to control your symptoms. C is decompensated where the medications do not work very well anymore and total failure is near. I had cirrhosis and was in stage B when I was given an estimate of 5 years left, but my cirrhosis was from primary biliary disease which is much different than hep C. I would suggest you talk to your doctor and ask him/her and also ask about the future possibility of transplant if you haven't already discussed this. You're young yet and would probably be an excellent candidate for a transplant at some time in the future. Of course, that would probably be way off in the future, probably many years since you are still in the compensated stage, but it's good to find out things and educate yourself especially when it is your own health. Answered by Carlyn Shani 4 months ago.

This Site Might Help You. RE: how long a person with compensated cirrhosis of the liver can live? i'VE BEEN DIAGDOSED WITH CHRONIC HEPATITIS C AND COMPENSATED CIRRHOSIS OF THE LIVER I AM A MALE 31 Y/O . TREATMENT FOR HEP C DID NOT WORK FOR ME (( PEGINTRON , REBETOL ) Answered by Margery Ort 4 months ago.


Are rebatol and pegintron forms of chemotherapy??
Asked by Arline Ishihara 4 months ago.

These are not chemotherapy for cancer, but rather for hepa C: PEG-Intron, peginterferon alfa-2b, is indicated for use alone or in combination with REBETOL (ribavirin, USP) for the treatment of chronic hepatitis C in patients with compensated liver disease who have not been previously treated with interferon alpha and are at least 18 years of age. REBETOL (ribavirin, USP) Capsules and Oral Solution are indicated in combination with INTRON A (interferon alfa-2b, recombinant) Injection for the treatment of chronic hepatitis C in patients 18 years of age and older with compensated liver disease previously untreated with alpha interferon and in patients 18 years of age and older who have relapsed following alpha interferon therapy. Hepatitis C: * Chronic infection: 55%-85% of infected persons * Chronic liver disease: 70% of chronically infected persons * Deaths from chronic liver disease: 1%-5% of infected persons may die * Leading indication for liver transplant Answered by Agueda Rapoza 4 months ago.

Chemotherapy is the use of chemical substances to treat disease. PEG-Intron + Rebetol is an FDA approved combination therapies for Hepatits C Virus (HCV). So, YES it is a form of chemotherapy . I understand the confusion in your mind. I am sure it is because in the modern-day use of the term "chemotherapy", it refers primarily to cytotoxic drugs used to treat cancer. In the real sense however, chemotherapy is suppose to mean any usage of chemical substances to treat disease. For example: using antibiotics is a form of chemotherapy in the real essence of the term. To clarify: PEG-Intron + Rebetol are forms of chemotherapy but not for cancer. It is a treatment for HCV. Answered by Floretta Collingwood 4 months ago.


Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
020903/001 REBETOL RIBAVIRIN CAPSULE/ORAL 200MG **Indicated for use and comarketed with Interferon ALFA-2B, Recombinant (INTRON A), as Rebetron Combination Therapy**
020903/002 REBETOL RIBAVIRIN CAPSULE/ORAL 200MG
021546/001 REBETOL RIBAVIRIN SOLUTION/ORAL 40MG per ML

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
018859/001 VIRAZOLE RIBAVIRIN FOR SOLUTION/INHALATION 6GM per VIAL
020903/001 REBETOL RIBAVIRIN CAPSULE/ORAL 200MG **Indicated for use and comarketed with Interferon ALFA-2B, Recombinant (INTRON A), as Rebetron Combination Therapy**
020903/002 REBETOL RIBAVIRIN CAPSULE/ORAL 200MG
021511/001 COPEGUS RIBAVIRIN TABLET/ORAL 200MG
021511/002 COPEGUS RIBAVIRIN TABLET/ORAL 400MG
021546/001 REBETOL RIBAVIRIN SOLUTION/ORAL 40MG per ML
076192/001 RIBAVIRIN RIBAVIRIN CAPSULE/ORAL 200MG
076203/001 RIBASPHERE RIBAVIRIN CAPSULE/ORAL 200MG
076277/001 RIBAVIRIN RIBAVIRIN CAPSULE/ORAL 200MG
077053/001 RIBAVIRIN RIBAVIRIN TABLET/ORAL 200MG
077094/001 RIBAVIRIN RIBAVIRIN TABLET/ORAL 200MG
077094/002 RIBAVIRIN RIBAVIRIN TABLET/ORAL 400MG
077094/003 RIBAVIRIN RIBAVIRIN TABLET/ORAL 600MG
077094/004 RIBAVIRIN RIBAVIRIN TABLET/ORAL 500MG
077224/001 RIBAVIRIN RIBAVIRIN CAPSULE/ORAL 200MG
077456/001 RIBAVIRIN RIBAVIRIN TABLET/ORAL 200MG
077456/002 RIBAVIRIN RIBAVIRIN TABLET/ORAL 400MG
077456/003 RIBAVIRIN RIBAVIRIN TABLET/ORAL 600MG
077611/001 RIBAVIRIN RIBAVIRIN SOLUTION/ ORAL 40MG per ML
077743/001 RIBAVIRIN RIBAVIRIN TABLET/ORAL 200MG
079111/001 RIBAVIRIN RIBAVIRIN TABLET/ORAL 200MG
079117/001 RIBAVARIN RIBAVIRIN CAPSULE/ORAL 200MG
202546/001 RIBAVIRIN RIBAVIRIN TABLET/ORAL 200MG
202546/002 RIBAVIRIN RIBAVIRIN TABLET/ORAL 400MG
202546/003 RIBAVIRIN RIBAVIRIN TABLET/ORAL 500MG
202546/004 RIBAVIRIN RIBAVIRIN TABLET/ORAL 600MG
207366/001 RIBAVIRIN RIBAVIRIN FOR SOLUTION/INHALATION 6GM per VIAL

Manufacturers

Manufacturer name
Merck Sharp & Dohme Ltd

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