Application Information

This drug has been submitted to the FDA under the reference 016647/001.

Names and composition

"QUINAGLUTE" is the commercial name of a drug composed of QUINIDINE GLUCONATE.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
016647/001 QUINAGLUTE QUINIDINE GLUCONATE TABLET, EXTENDED RELEASE/ORAL 324MG

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
007529/002 QUINIDINE GLUCONATE QUINIDINE GLUCONATE INJECTABLE/INJECTION 80MG per ML
016647/001 QUINAGLUTE QUINIDINE GLUCONATE TABLET, EXTENDED RELEASE/ORAL 324MG
017917/001 DURAQUIN QUINIDINE GLUCONATE TABLET, EXTENDED RELEASE/ORAL 330MG
085978/001 QUINACT QUINIDINE GLUCONATE TABLET/ORAL 266MG
086099/001 QUINACT QUINIDINE GLUCONATE TABLET/ORAL 400MG
087448/001 QUINATIME QUINIDINE GLUCONATE TABLET, EXTENDED RELEASE/ORAL 324MG
087785/001 QUINIDINE GLUCONATE QUINIDINE GLUCONATE TABLET, EXTENDED RELEASE/ORAL 324MG
087810/001 QUINIDINE GLUCONATE QUINIDINE GLUCONATE TABLET, EXTENDED RELEASE/ORAL 324MG
088081/001 QUINALAN QUINIDINE GLUCONATE TABLET, EXTENDED RELEASE/ORAL 324MG
088431/001 QUINIDINE GLUCONATE QUINIDINE GLUCONATE TABLET, EXTENDED RELEASE/ORAL 324MG
088582/001 QUINIDINE GLUCONATE QUINIDINE GLUCONATE TABLET, EXTENDED RELEASE/ORAL 324MG
089164/001 QUINIDINE GLUCONATE QUINIDINE GLUCONATE TABLET, EXTENDED RELEASE/ORAL 324MG
089338/001 QUINIDINE GLUCONATE QUINIDINE GLUCONATE TABLET, EXTENDED RELEASE/ORAL 324MG
089476/001 QUINIDINE GLUCONATE QUINIDINE GLUCONATE TABLET, EXTENDED RELEASE/ORAL 324MG
089894/001 QUINIDINE GLUCONATE QUINIDINE GLUCONATE TABLET, EXTENDED RELEASE/ORAL 324MG

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Answered questions

What are the 38 drugs that can cause drug-induced lupus?
I just heard that someone can have drug-induced lupus. My mother-in-law has lupus and is on a multitude of medications (for God knows what; since before diagnosed with lupus) so this issue has peaked my interest.From doing a search, I could only find the top three medications, but I was hoping someone could... Asked by Jeannine Kravs 1 year ago.

I just heard that someone can have drug-induced lupus. My mother-in-law has lupus and is on a multitude of medications (for God knows what; since before diagnosed with lupus) so this issue has peaked my interest. From doing a search, I could only find the top three medications, but I was hoping someone could tell me the 38 drugs that can cause lupus. Thank you! Answered by Miranda Cwiek 1 year ago.

can it be cause by Keppra or Lamictal . I used to take Dilantin and tegretol as well as mysoline. But haven't taken them for years. I have been on Lamictal since it came out on the market with tegretol for most of it till 2005 Then in 2007 I began the keppra. I was diagnosed with Lupus back in 2013, after they found I had hyper thyroidism/ Graves Disease, RA and a few other problems. They told me they're all connected and can stem from the anti seizure drugs. i don't see them on any lists but do see anti seizure drugs. I'm concerned. As the combination or the 2 drugs have given me control of my seizures. BUt At what price must i live with if I want to keep control. As stopping them to stop the lupus could cause me to spiral back into the dark pit pof no control and leave me homebound again. Answered by Floy Pittman 1 year ago.

Drug Induced Lupus Answered by Sheena Cuervo 1 year ago.

Some drugs used to control high blood pressure and tuberculosis can cause drug induced lupus which goes away when you stop the medication.These are the most common. If you already have lupus, these drugs could make it flare. Sulfa based antibiotics can also cause flares. Answered by Earline Kross 1 year ago.

Her rheumatologist will certainly look over her list of medications. S/he will spot any that can cause drug induced lupus. If the lupus is drug induced, it will go away when the medication is withdrawn. Some of the medications listed by femmina matt are high blood pressure meds and anti TB meds. Answered by Bradford Labita 1 year ago.


Can medication cause lupus?
My mom is 54 and she has ben diagnosed with lupus. She is on 3 diarhettics (sp?) and blood pressure meds. Plus she has to take 4 potassium horse pills 4 times a day!!!!!!! Is there ny research that being over medicated can bring on lupus, and if so, is it reversible? Asked by Ollie Ven 1 year ago.

Lupus-inducing drugs are typically those used to treat chronic diseases. No obvious common denominator links the drugs that are likely to cause lupus. The list includes medicines used to treat: * Heart disease * Thyroid disease * Hypertension * Neuropsychiatric disorders * Certain anti-inflammatory agents and antibiotics. At least 38 drugs currently in use can cause DILE. However, most cases have been associated with these three: * procainamide (Pronestyl) * hydralazine (Apresoline) * quinidine (Quinaglute). Despite the symptoms of lupus and the potential side-effects of treatment, people with lupus can maintain a high quality of life overall. One key to managing lupus is to understand the disease and its impact. Learning to recognize the warning signs of a flare can help the patient take steps to ward it off or reduce its intensity. Many people with lupus experience increased fatigue, pain, a rash, fever, abdominal discomfort, headache, or dizziness just before a flare. Developing strategies to prevent flares can also be helpful, such as learning to recognize your warning signals and maintaining good communication with your doctor. It is also important for people with lupus to receive regular health care, instead of seeking help only when symptoms worsen. Results from a medical exam and laboratory work on a regular basis allows the doctor to note any changes and to identify and treat flares early. The treatment plan, which is tailored to the individual’s specific needs and circumstances, can be adjusted accordingly. If new symptoms are identified early, treatments may be more effective. Other concerns also can be addressed at regular checkups. The doctor can provide guidance about such issues as the use of sunscreens, stress reduction, and the importance of structured exercise and rest, as well as birth control and family planning. Because people with lupus can be more susceptible to infections, the doctor may recommend yearly influenza vaccinations or pneumococcal vaccinations for some patients. Women with lupus should receive regular preventive health care, such as gynecological and breast examinations. Men with lupus should have the prostate-specific antigen (PSA) test. Both men and women need to have their blood pressure and cholesterol checked on a regular basis. If a person is taking corticosteroids or antimalarial medications, an eye exam should be done at least yearly to screen for and treat eye problems. Learning to recognize the warning signs of a flare can help the patient take steps to ward it off or reduce its intensity. Staying healthy requires extra effort and care for people with lupus, so it becomes especially important to develop strategies for maintaining wellness. Wellness involves close attention to the body, mind, and spirit. One of the primary goals of wellness for people with lupus is coping with the stress of having a chronic disorder. Effective stress management varies from person to person. Some approaches that may help include exercise, relaxation techniques such as meditation, and setting priorities for spending time and energy. Developing and maintaining a good support system is also important. A support system may include family, friends, medical professionals, community organizations, and support groups. Participating in a support group can provide emotional help, boost self-esteem and morale, and help develop or improve coping skills. Answered by Ressie Seidler 1 year ago.

High blood pressure medications can cause drug induced lupus. However, you have to balance the high blood pressure issues, which are very very dangerous, against the lupus issues. Only her doctors can do that. Her rheumatologist and the doctor who is treating her other issues MUST work together. Make sure they do. Generally, drug induced lupus goes away when the offending medication is removed. However, you need to talk with the doctors to find out IF the blood pressure meds she is taking are those that can trigger lupus. Don't try to manage this yourself. It can all be life threatening. You are assuming that she is over medicated. How do you know that? Do you really think that people on Yahoo Answers will be able to tell you what to do, better than a doctor? If you don't trust her doctors, get new ones. Do some reading about DIL or drug induced lupus at the link provided. You don't KNOW that her lupus is drug induced. She may have developed systemic lupus not as a result of the medications she takes. I am begging you not to fool around with your mom's life by asking nincompoops on Yahoo Answers! What will you do? Ask her to stop her meds so she can have a heart attack or stroke because someone here thought it was a good idea? You and your mom need to TALK with the docs and get some answers there. Answered by Alissa Daughtridge 1 year ago.

Medications that may play a role in inducing lupus include: ACE inhibitors (captopril, lisinopril). Procainamide hydrochloride. Hydralazine hydrochloride. Isoniazid. Certain anticonvulsants called hydantoins, such as phenytoin and ethotoin. Chlorpromazine hydrochloride. Methyldopa. Minocycline. Interferon alfa. D-penicillamine. Antibodies to tumor necrosis factor-a. Certain medications can cause temporary symptoms and signs of lupus. The symptoms go away when you stop taking the medication, generally within a few weeks. Symptoms are usually milder than in typical lupus, and the kidneys and central nervous system are rarely affected. Though this list includes certain antihypertensives, there are no diuretics here. Wishing all the best for your Mom! Answered by Mirta Soeder 1 year ago.

Some drugs used to control high blood pressure and tuberculosis can cause drug induced lupus which goes away when you stop the medication.These are the most common. If you already have lupus, these drugs could make it flare. Sulfa based antibiotics can also cause flares. Answered by Nelda Duffield 1 year ago.


What are the possible medications that cause drug induced lupus?
I HEARD ANTIBIOTICS AND HIGH BLOOD PRESSURE MED'S ANY OTHERS?? also IM FINDING MIXED OPPINIONS ON WHETHER DOXICYCLINE "CAUSES" OR "TREATS" LUPUS? ANYONE HAVE FACTS ON THAT? Asked by Masako Harrow 1 year ago.

"Although as many as 100 drugs have been reported to cause DRL, most cases are caused by the following 4 drugs: procainamide (Pronestyl), hydralazine (Apresoline), minocycline, and quinidine (Quinaglute). With these 4 drugs, the risk of developing DRL after 2 years of drug use is 5-20 percent. With the other drugs reported to cause DRL, the risk is less than 1 percent." A previous YA response to your second question: "Doxicycline: It can cause SLE and it should not be given to patients with SLE where it could exacerbate or worsen the said condition. Therefore, it cannot be used to treat lupus. Antibiotics, such as tetracycline, are often used for a given time frame to be able to work its best. Unfortunately, some people think that it would be better to take it for an extended period of time to make sure that it does its work completely. This is a misconception since the body has a way of getting immune to antibiotics. When this happens, it can produce adverse results instead of helping the body out such as growth of other organisms, and inducing other conditions to arise." Answered by Lola Elfert 1 year ago.

hydralazine sulphas see list attached Answered by Carl Broll 1 year ago.


Tired all the time and don't know why!?
I am tired all the time and don't know why. Any suggestions on what to try for energy? Asked by Tracy Youmans 1 year ago.

Lethargy is a medical condition characterized by drowsiness, slowness, general indifference, or tiredness. The condition may also be called malaise, fatigue, or listlessness. While lethargy may be a response to stress or overexertion, it can also be a symptom of many serious illnesses and problems. Some lifestyle and dietary choices can lead to lethargy. These include failing to drink enough fluids and eating heavy foods such as whole milk ice cream and red meat. Staying in bed for too long and failure to get up and move around can make a person feel lethargic as well. Conversely, drinking water regularly, eating healthy, and exercising can battle feelings of lethargy. Certain medications have been known to cause lethargy as a side effect. Some of these include calcium gluconate, Crystodigin, Digitaline, digitoxin, and Kalcinate. In addition, combinations of certain medications can cause lethargy. Typical drug interactions that can lead to lethargy include Lanoxin and Cardioquin, Lanoxin and Quinaglute, Lanoxin and Quinidex, and Trizivir and acyclovir. This list is not exhaustive. Therefore, a person taking medication should consult with his or her doctor to determine whether lethargy is a possible side effect. A variety of diseases and disorders are also associated with lethargy. Acute and chronic kidney failure, jaundice, and hepatitis can all cause lethargy. Thyroid disorders, including hypothyroidism and autoimmune thyroid diseases, are also associated with lethargy. Even psychological disorders can cause a person to experience lethargy. Bipolar disorder, depression and other depressive disorders, and dysthymia can each be responsible for lethargy. Similarly, life changes such as menopause, as well as shock, can cause one to feel lethargic. Common illnesses, such as constipation, can also lead to lethargy. Numerous other serious diseases, such as Addison’s disease, Chagas disease, meningitis, and opsoclonus myoclonus are associated with symptoms of lethargy. Additional disorders and diseases that may cause lethargy include bronchiolitis, gastritis, enterocolitis, discitis, and myxedema. Since the diseases and disorders associated with lethargy are so varied, it is important to take it seriously when the symptom presents itself. Although it may be caused by something simple, such as constipation or simple lack of sleep, lethargy can also be a sign of a potentially fatal illness. Answered by Deanne Hamblet 1 year ago.

Even if you are the slightest bit anemic (the iron deficient type) it can have a big impact on your energy level... I know, I've been there. I recommend making an appointment with your physician and have a simple blood test done on your blood. If it turns out that you are in fact anemic, an iron supplement will correct the problem quickly and easily. It's actually quite common for females to be iron deficiency related anemic, due to their menses cycles every month. Answered by Serafina Loduca 1 year ago.

it is important to stay hydrated, lack of hydration can make you tired and give you headaches, make sure to drink water, lots of water, and if you drink a lot of coffee or caffeinated drinks you need to intake more water, it dries you out or maybe ur anemic as someone else suggested Answered by Toney Proulx 1 year ago.

maybe you should check your iron intake. i read somehwre that lack of iron causes laziness and tiredness Answered by Scott Macedonio 1 year ago.


Breathing troubles?
Thank you for all the answers so far!I see a psychiatrist who prescribes my meds. I've been on this combo for several years. Because I have such poor quality sleep, when I do sleep, the Provigil is taken in the morning to help me keep going.Strattera is used (by me) originally for ADD to help quiet racing... Asked by Lang Leger 1 year ago.

I suffer from anxiety and take meds for it (Lexapro, Stratter, Provigil) but my sleep schedule has been incredibly out of whack... I rarely ever have noticeable anxiety until it's time to go to bed. I've been this way since a child and I'm almost 34! The bad habit I've developed because of it is- I don't go to sleep until exhaustion overtakes me. I'm almost used to living like that. What I can't stand, though is: I "cannot" breathe!!! I constantly feel like I must yawn to get a good lungful of air. I *know* I'm breathing fine (I've never passed out because of it lol), so what gives? When I was a kid I was curios how long I could breathe the same air in a paper bag lol- that is how I feel now: like I'm getting air, but it's no good. Other than doing the impossible and actually sleeping like a normal person, does anyone know what I could do to help me feel like I'm breathing alright? Thanks! Answered by Stacia Pledger 1 year ago.

Thank you for all the answers so far! I see a psychiatrist who prescribes my meds. I've been on this combo for several years. Because I have such poor quality sleep, when I do sleep, the Provigil is taken in the morning to help me keep going. Strattera is used (by me) originally for ADD to help quiet racing thoughts, but over the years I've noticed a huge improvement toward my anxiety symptoms and my pdoc said in a small subset of people the med helps lower anxiety as does Provigil. My sleep problems are getting worse though, as is my breathing. Even my general practicioner/OBGYN writes my breathing problems off as anxiety (well, 5 + years ago she did lol and I've not been back) and I've missed my pdoc app. for the past 2 months and life has been been stressful. I HATE seeing a doctor and having my complaints written off as anxiety, so I'd rather not bother, but I have other things I need to see a doc for so I need to get off my butt and go back. Thanks again!! Answered by Arthur Wiborg 1 year ago.

Well for one, Provigil is used to prevent sleepiness sooo one thing that may help is to see about lowering the dosage. On the other hand, here is some info on Stattera.... Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking Strattera and call your doctor at once if you have a serious side effect such as: chest pain, shortness of breath, fast or uneven heartbeats; feeling light-headed or fainting; unusual thoughts or behavior, aggression, hallucinations (seeing things that are not there); increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure); or urinating less than usual or not at all. Less serious side effects may include: feeling irritable; feeling dizzy or drowsy; nausea, vomiting, stomach pain, loss of appetite, constipation; cough, dry mouth; skin rash or itching; sleep problems (insomnia); increased menstrual cramps; or impotence, loss of interest in sex, or trouble having an orgasm. Before taking atomoxetine(Strattera), tell your doctor if you are using any of the following drugs: albuterol (Proventil, Ventolin); amiodarone (Cordarone, Pacerone); bupropion (Wellbutrin, Zyban); celecoxib (Celebrex); cimetidine (Tagamet); doxorubicin (Adriamycin); methadone (Dolophine, Methadose); metoclopramide (Reglan); quinidine (Cardioquin, Quinaglute, Quinidex); ritonavir (Norvir); ranitidine (Zantac); terbinafine (Lamisil); antidepressants such as citalopram (Celexa), clomipramine (Anafranil); escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft); or antihistamines or sleep medicine such as diphenhydramine (Benadryl, Unisom, and others) or chlorpheniramine (Chlor-Trimeton and others). With this in mind, you may want to talk to you Dr. I never heard of Strattera being used for anxiety. I do know that it is a SNRI and is usually prescibed for short term use (in adults 10 wks). Lexapro however is a SSRI used for depression and anxiety. In my own personal experience, Lexapro actually increased my panic attacks to the point of SI and hypervent. & passing out. :( The breathing issue really sounds like you're hyperventing (or at least on the brink of it) which is a symptom of an anxiety attack and just makes it worse. In the mean time, try slow "square breathing" into a thin, cold, wet washcloth until you can get in to see your Dr. For me, it took changing to Zoloft and adding Klonopin .5mg b.i.d. to finally ease the panic and depression. Agape Sister. I hope all goes well. Answered by Cordie Wojtak 1 year ago.

Sleeping in an inclined position will allow you to breathe much easier. You can do this by propping lots of pillows under your head and upper body. Making love before bedtime will release certain hormones which will induce you to fall asleep afterwards. If you don't have a partner right now, masturbation can achieve the same results. Judging from your description, it appears that you are not a physically active person. So it is time to get your body moving. Aerobic exercise can reduce the symptoms of anxiety disorder. Doing pushups can help expand your ribcage and strengthen your breathing muscles. Answered by Lewis Jesperson 1 year ago.

I'm not a doctor, or even in the medical field, but you seem very tormented. I've seen people that have trouble breathing, and for the most part they look almost gray from the lack of oxygen. Growing up we played hard, sand lot football, baseball, basketball, all kinds of games. One of the hazards was getting the breath knocked out of you. When it happens, it is terrifying, you can't breath. But after the 30 th or so times of that happening you learn to relax, knowing that you lungs will re inflate and you will be able to breath again. So I know your pain. Also I suffer from Acid Reflux, and occasionally, I'll have an episode while I'm sleeping, and inhale that mess into my lungs. I wake up coughing, and about 20 seconds into that I'll go into a athasma attack, and then I can't get any air in but this little stream that I cough right back out. Again, I have to relax and not panic, otherwise it just gets worse. You have to do some convincing of yourself that you're ok, you color is good. Also exercising an hour before bedtime would be good. Get your heart rate up and breathe some big air. Get a good hot shower and then go to bed. Sleeping is easy, I had a high school psych. teacher who sold me on the low down on this. The key is to relax your face, concentrate on relaxing it. Next it spreads to your neck, and shoulders, arms, torso, hips, thighs, knees,calves, ankles, and finally you feet and hands. Usually I am asleep 30 seconds after my head hits the pillow. Taking medication on a regular bases, to me, is a psychological defeat, especially for anxiety. The pharmaceutical companies are trying to make hypochondriacs out of all of us. I won't take an aspirin, unless, I really really need it, that way when I do take one, it works really really well. I do enjoy lots of dopamine, the body's natural drug. Sex is a big resource for that, especially gut wrenching orgasms, and lots of them 4 or 5 times a week. Sex is fun, its good exercise, and it feels good. Loose the religious inhibitions about it, which was just a mechanism to control everyone, and start enjoying life. Alright, I've said enough. Answered by Arthur Lockart 1 year ago.

This happened with me in my 1st pregnancy. My daughter was huge and I carried high and my lungs had no room and I was always out of breath. I never had to go get oxygen or anything like that. Answered by Tracie Rische 1 year ago.

Have you been referred to a heart lung specialist? It may not be all anxiety, but a combination of things. Ask your MD for a referal to a good Cardio Pulmonary doctor. They can run tests. I wish you the best Answered by Ella Mcginnis 1 year ago.


Avelox and magnesium,aluminum?
im taking avelox antibiotic for my thorat bacterial infection....i brought guava juice today but i think it contains magnesium or aluminum....how long after taking avelox can i drink the guava juice???? Asked by Somer Wohlwendi 1 year ago.

It's difficult question, but i am trying to answer... Should avoid while taking Avelox: Avoid prolonged exposure to sunlight or tanning beds. Avelox may make your skin more sensitive to sunburn. Wear protective clothing and use sunscreen if you must be out in the sun while using Avelox. Call your doctor if you have severe burning, redness, itching, rash, or swelling after being in the sun. Avelox can cause side effects that may impair your thinking or reactions. If this happens, avoid driving or doing anything that requires you to be awake and alert. Important information about Avelox: Take this medication for as many days as it has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Avelox will not treat a viral infection such as the common cold or flu. Do not use Avelox without first talking to your doctor if you or any member of your family have a heart condition known as long QT syndrome. Also, do not use Avelox if you are also using a heart rhythm medicine such as quinidine (Cardioquin, Quinidex, Quinaglute), procainamide (Pronestyl, Procan SR), amiodarone (Cordarone, Pacerone), sotalol (Betapace), and others. Certain other drugs can make Avelox less effective when taken at the same time. The following medicines should be taken at least 4 hours after or 8 hours before you take Avelox: antacids that contain magnesium, calcium, or aluminum (such as Tums, Rolaids, Maalox); the ulcer medicine sucralfate (Carafate); vitamin or mineral supplements that contain iron or zinc; didanosine chewable/buffered tablets or pediatric powder for oral solution (ddI, Videx, Videx Pediatric, and others). Avelox may make your skin more sensitive to sunburn. Avoid prolonged exposure to sunlight or tanning beds, and wear protective clothing and sunscreen when you are outdoors. Call your doctor if you have severe burning, redness, itching, rash, or swelling after being in the sun. Answered by Jackeline Homrich 1 year ago.


Can you take benadryl with biaxon?
Asked by Cassey Wobbleton 1 year ago.

As everyone else who answered has said, yes it is safe to give your dog Benadryl. The general rule of thumb is to give 1 mg for every 1 pound of body weight. In your case, you would give your dog 45 mg. You need to consult w/ a veterinarian before doing this though. He may up the dosage or cut it back depending on the severity of your dog's allergies. You can always just call him and ask instead of taking your dog in, but I suggest taking him in for an exam to rule out fleas or mites. Your vet can also give her a steroid shot called Depo Medrol to help w/ the itching. Good luck and I hope your dog gets some relief soon! Answered by Tamica Balcerzak 1 year ago.


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