Application Information

This drug has been submitted to the FDA under the reference 006460/002.

Names and composition

"PROTAMINE SULFATE" is the commercial name of a drug composed of PROTAMINE SULFATE.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
006460/002 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 10MG per ML **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
007413/001 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 50MG per VIAL
007413/002 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 250MG per VIAL
089306/001 PROTAMINE SULFATE PROTAMINE SULFATE Injectable/ Injection 10MG per ML
089307/001 PROTAMINE SULFATE PROTAMINE SULFATE Injectable/ Injection 50MG per VIAL
089454/001 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 10MG per ML
089474/001 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 10MG per ML
089475/001 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 10MG per ML

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
006460/002 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 10MG per ML **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
007413/001 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 50MG per VIAL
007413/002 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 250MG per VIAL
089306/001 PROTAMINE SULFATE PROTAMINE SULFATE Injectable/ Injection 10MG per ML
089307/001 PROTAMINE SULFATE PROTAMINE SULFATE Injectable/ Injection 50MG per VIAL
089454/001 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 10MG per ML
089474/001 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 10MG per ML
089475/001 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 10MG per ML

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Answered questions

Does anyone know the chemical structure of protamine sulfate?
A diagram would be helpful. Any related information on protamine sulfate and its impurities and associated LC assay/impurity methods would be excellent. Asked by Willa Lozowski 1 year ago.

I know that protamines are small, arginine-rich, nuclear proteins that replace histones late in the haploid phase of spermatogenesis and are believed essential for sperm head condensation and DNA stabilization, as for the chemical structure: There is not one available. Could you be asking for something else? Answered by Lanita Fangman 1 year ago.

Protamine Sulfate Structure Answered by Fatimah Navor 1 year ago.

I agree with Pureology and Aveda, but personally, I find them to be way too expensive, with Pureology being about as high end as it gets (with Kerastase and Sisley). A cheaper alternative would be Burt's Bees. They have tons of formulas, and even tell how much % natural the products are on them. Answered by Grover Odums 1 year ago.

originalsmartie has answered your question and you should award her full 10 points. There is no chemical structure. There is no diagram. Answered by Quinton Gan 1 year ago.


Why is protamine sulfate injected at the end of dialysis?
Homework help! And if so why is it injected in the venous tube and not the arterial tube? -Thanks! Asked by Beatrice Loskill 1 year ago.

People are given heparin, an IV blood thinner, during dialysis to avoid blood clotting. Protamine sulfate is heparin's antidote and will stop its effects. It goes in the venous circulation because that's the right direction (toward the heart). Answered by Aleshia Dumm 1 year ago.


Why is protamine sulfate injected in the venous tube and not the arterial tube?
During kidney dialysis, why is the protamine sulfate injected in the venous tube and not the arterial tube? Please help. Asked by Harlan Micheals 1 year ago.

I don't know Answered by Lance Boncella 1 year ago.


What would happen if you say gave a patient 10mg of protamine Sulfate?
Without 1000 active units of heparin in their body Asked by Fiona Puliafico 1 year ago.

Probably not much but you run the risk of pulmonary hypertension, systemic hypotension, pulmonary edema or an allergic reaction. Answered by Flor Grumbling 1 year ago.


The recommended antidote for a heparin overdose is?
Asked by Shara Bojanowski 1 year ago.

protamine sulphate will reverse anticoagulation of hep. Answered by Breana Kreb 1 year ago.

Antidote For Heparin Answered by Kimberly Kikkert 1 year ago.

Heparin Antidote Answered by Tomiko Kornprobst 1 year ago.

protamine sulfate Answered by Nilsa Manely 1 year ago.


You are delivering medications to the hospital floors when you hear a commotion.?
the nurse tells you that a bag of Heparin accidentally ran at 4 times the rate, and the patient is starting to bleed. immediately you pick up the phone to call the pharmacy. what medication will you ask the technician to get from the pharmacist, because the pt will require it soon? why? Asked by Mitchell Asevedo 1 year ago.

The answer is Protamine Sulfate, it is a heparin antagonist. Vitamin K is the antidote for a Warfarin (Coumadin) overdose. Answered by Alisa Shost 1 year ago.

Protamine Sulfate to stop the anti-coagulating effect .... and a double scotch for the stupid idiot who overdosed the patient. Makes getting fired easier to take. Answered by Alejandro Bukrim 1 year ago.

Protamine sulfate Answered by Elsy Kaleiwahea 1 year ago.

a coagulant,if the patient is bleeding then you need to staunch the flow of blood,also saisaline replace the lost fluids. Answered by Cornell Royle 1 year ago.

Its not your job, you can call make the call but the other floors need you to stock their rooms with meds sounds as if the nurse screwed up! Answered by Paula Stromyer 1 year ago.

intravenous vitamin K? Some thing that helps clot that is for sure Answered by Man Heady 1 year ago.

i agree with christelle the patiant is not getting enogh vitamin k Answered by Amal Furuya 1 year ago.


Blood clots?
is there a way to give someone blood clots in there heart i man is there anywya a human can do something to give people blood clots or help it start clotting? Asked by Arlene Jahnel 1 year ago.

Vitamin K does increase blood's propensity to clot, as does Protamine Sulfate. Shouldn't cause clots in your heart though. Air introduced into a vein via iv access could cause an embolism, but it would take more than what they show on TV ... I have been told by an ED doc that it would take AT LEAST a 10 mL bolus ... . Good luck on this. Answered by Sung Suthoff 1 year ago.

No, there is not. Answered by Clarinda Holling 1 year ago.


Does anyone know the chemical structure of protamine sulfate?
A diagram would be helpful. Any related information on protamine sulfate and its impurities and associated LC assay/impurity methods would be excellent. Asked by Magdalen Mottley 1 year ago.

I know that protamines are small, arginine-rich, nuclear proteins that replace histones late in the haploid phase of spermatogenesis and are believed essential for sperm head condensation and DNA stabilization, as for the chemical structure: There is not one available. Could you be asking for something else? Answered by Virgil Callins 1 year ago.

Protamine Sulfate Structure Answered by Judy Cooksley 1 year ago.

I agree with Pureology and Aveda, but personally, I find them to be way too expensive, with Pureology being about as high end as it gets (with Kerastase and Sisley). A cheaper alternative would be Burt's Bees. They have tons of formulas, and even tell how much % natural the products are on them. Answered by Beatrice Postert 1 year ago.

originalsmartie has answered your question and you should award her full 10 points. There is no chemical structure. There is no diagram. Answered by Daphne Oats 1 year ago.


Why is protamine sulfate injected at the end of dialysis?
Homework help! And if so why is it injected in the venous tube and not the arterial tube? -Thanks! Asked by Hilaria Lauritsen 1 year ago.

People are given heparin, an IV blood thinner, during dialysis to avoid blood clotting. Protamine sulfate is heparin's antidote and will stop its effects. It goes in the venous circulation because that's the right direction (toward the heart). Answered by Rosaline Vollbrecht 1 year ago.


Why is protamine sulfate injected in the venous tube and not the arterial tube?
During kidney dialysis, why is the protamine sulfate injected in the venous tube and not the arterial tube? Please help. Asked by Mertie Amweg 1 year ago.

I don't know Answered by Rachell Strege 1 year ago.


What would happen if you say gave a patient 10mg of protamine Sulfate?
Without 1000 active units of heparin in their body Asked by Prince Hortman 1 year ago.

Probably not much but you run the risk of pulmonary hypertension, systemic hypotension, pulmonary edema or an allergic reaction. Answered by Sana Gilberg 1 year ago.


The recommended antidote for a heparin overdose is?
Asked by Tamera Costanza 1 year ago.

protamine sulphate will reverse anticoagulation of hep. Answered by Tiesha Mordhorst 1 year ago.

Antidote For Heparin Answered by Susanna Dolberry 1 year ago.

Heparin Antidote Answered by Nancey Ayhens 1 year ago.

protamine sulfate Answered by Earlene Hunker 1 year ago.


You are delivering medications to the hospital floors when you hear a commotion.?
the nurse tells you that a bag of Heparin accidentally ran at 4 times the rate, and the patient is starting to bleed. immediately you pick up the phone to call the pharmacy. what medication will you ask the technician to get from the pharmacist, because the pt will require it soon? why? Asked by Dianne Fabio 1 year ago.

The answer is Protamine Sulfate, it is a heparin antagonist. Vitamin K is the antidote for a Warfarin (Coumadin) overdose. Answered by Helaine Adinolfi 1 year ago.

Protamine Sulfate to stop the anti-coagulating effect .... and a double scotch for the stupid idiot who overdosed the patient. Makes getting fired easier to take. Answered by Ivelisse Trucker 1 year ago.

Protamine sulfate Answered by Leroy Reger 1 year ago.

a coagulant,if the patient is bleeding then you need to staunch the flow of blood,also saisaline replace the lost fluids. Answered by Tawanda Lamay 1 year ago.

Its not your job, you can call make the call but the other floors need you to stock their rooms with meds sounds as if the nurse screwed up! Answered by Vasiliki Hurles 1 year ago.

intravenous vitamin K? Some thing that helps clot that is for sure Answered by Marvin Fruchter 1 year ago.

i agree with christelle the patiant is not getting enogh vitamin k Answered by Wendy Alexader 1 year ago.


Blood clots?
is there a way to give someone blood clots in there heart i man is there anywya a human can do something to give people blood clots or help it start clotting? Asked by Evelynn Chrestman 1 year ago.

Vitamin K does increase blood's propensity to clot, as does Protamine Sulfate. Shouldn't cause clots in your heart though. Air introduced into a vein via iv access could cause an embolism, but it would take more than what they show on TV ... I have been told by an ED doc that it would take AT LEAST a 10 mL bolus ... . Good luck on this. Answered by Alba Cocoran 1 year ago.

No, there is not. Answered by Maryalice Saxton 1 year ago.


Does anyone know the chemical structure of protamine sulfate?
A diagram would be helpful. Any related information on protamine sulfate and its impurities and associated LC assay/impurity methods would be excellent. Asked by Torrie Nerren 1 year ago.

I know that protamines are small, arginine-rich, nuclear proteins that replace histones late in the haploid phase of spermatogenesis and are believed essential for sperm head condensation and DNA stabilization, as for the chemical structure: There is not one available. Could you be asking for something else? Answered by Shery Maronge 1 year ago.

Protamine Sulfate Structure Answered by Eleanor Cagley 1 year ago.

I agree with Pureology and Aveda, but personally, I find them to be way too expensive, with Pureology being about as high end as it gets (with Kerastase and Sisley). A cheaper alternative would be Burt's Bees. They have tons of formulas, and even tell how much % natural the products are on them. Answered by Alanna Austria 1 year ago.

originalsmartie has answered your question and you should award her full 10 points. There is no chemical structure. There is no diagram. Answered by Chris Yocom 1 year ago.


Why is protamine sulfate injected at the end of dialysis?
Homework help! And if so why is it injected in the venous tube and not the arterial tube? -Thanks! Asked by Wilburn Stanganelli 1 year ago.

People are given heparin, an IV blood thinner, during dialysis to avoid blood clotting. Protamine sulfate is heparin's antidote and will stop its effects. It goes in the venous circulation because that's the right direction (toward the heart). Answered by Treasa Moede 1 year ago.


Why is protamine sulfate injected in the venous tube and not the arterial tube?
During kidney dialysis, why is the protamine sulfate injected in the venous tube and not the arterial tube? Please help. Asked by Aundrea Lepke 1 year ago.

I don't know Answered by Jeffery Stratis 1 year ago.


What would happen if you say gave a patient 10mg of protamine Sulfate?
Without 1000 active units of heparin in their body Asked by Margarite Wironen 1 year ago.

Probably not much but you run the risk of pulmonary hypertension, systemic hypotension, pulmonary edema or an allergic reaction. Answered by Kanisha Wertz 1 year ago.


The recommended antidote for a heparin overdose is?
Asked by Palmer Huesman 1 year ago.

protamine sulphate will reverse anticoagulation of hep. Answered by Elida Capoccia 1 year ago.

Antidote For Heparin Answered by Gaylene Bersamin 1 year ago.

Heparin Antidote Answered by Nathanial Agemy 1 year ago.

protamine sulfate Answered by Bertha Wuest 1 year ago.


You are delivering medications to the hospital floors when you hear a commotion.?
the nurse tells you that a bag of Heparin accidentally ran at 4 times the rate, and the patient is starting to bleed. immediately you pick up the phone to call the pharmacy. what medication will you ask the technician to get from the pharmacist, because the pt will require it soon? why? Asked by Liane Novelly 1 year ago.

The answer is Protamine Sulfate, it is a heparin antagonist. Vitamin K is the antidote for a Warfarin (Coumadin) overdose. Answered by Clarice Baughman 1 year ago.

Protamine Sulfate to stop the anti-coagulating effect .... and a double scotch for the stupid idiot who overdosed the patient. Makes getting fired easier to take. Answered by Troy Buress 1 year ago.

Protamine sulfate Answered by Elda Mikuszewski 1 year ago.

a coagulant,if the patient is bleeding then you need to staunch the flow of blood,also saisaline replace the lost fluids. Answered by Oliva Dollak 1 year ago.

Its not your job, you can call make the call but the other floors need you to stock their rooms with meds sounds as if the nurse screwed up! Answered by Denae Lecroy 1 year ago.

intravenous vitamin K? Some thing that helps clot that is for sure Answered by Nettie Stamp 1 year ago.

i agree with christelle the patiant is not getting enogh vitamin k Answered by Shalon Manzueta 1 year ago.


Blood clots?
is there a way to give someone blood clots in there heart i man is there anywya a human can do something to give people blood clots or help it start clotting? Asked by Lindsey Cabellon 1 year ago.

Vitamin K does increase blood's propensity to clot, as does Protamine Sulfate. Shouldn't cause clots in your heart though. Air introduced into a vein via iv access could cause an embolism, but it would take more than what they show on TV ... I have been told by an ED doc that it would take AT LEAST a 10 mL bolus ... . Good luck on this. Answered by Chere Herrman 1 year ago.

No, there is not. Answered by Lynette Weese 1 year ago.


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