Application Information

This drug has been submitted to the FDA under the reference 006460/002.

Names and composition

"PROTAMINE SULFATE" is the commercial name of a drug composed of PROTAMINE SULFATE.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
006460/002 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 10MG per ML **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
007413/001 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 50MG per VIAL
007413/002 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 250MG per VIAL
089306/001 PROTAMINE SULFATE PROTAMINE SULFATE Injectable/ Injection 10MG per ML
089307/001 PROTAMINE SULFATE PROTAMINE SULFATE Injectable/ Injection 50MG per VIAL
089454/001 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 10MG per ML
089474/001 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 10MG per ML
089475/001 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 10MG per ML

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
006460/002 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 10MG per ML **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
007413/001 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 50MG per VIAL
007413/002 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 250MG per VIAL
089306/001 PROTAMINE SULFATE PROTAMINE SULFATE Injectable/ Injection 10MG per ML
089307/001 PROTAMINE SULFATE PROTAMINE SULFATE Injectable/ Injection 50MG per VIAL
089454/001 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 10MG per ML
089474/001 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 10MG per ML
089475/001 PROTAMINE SULFATE PROTAMINE SULFATE INJECTABLE/INJECTION 10MG per ML

Ask a doctor

A licensed doctor will try to answer your question for free as quickly as possible. Free of charge during the beta period.

Answered questions

Does anyone know the chemical structure of protamine sulfate?
A diagram would be helpful. Any related information on protamine sulfate and its impurities and associated LC assay/impurity methods would be excellent. Asked by Willa Lozowski 2 years ago.

I know that protamines are small, arginine-rich, nuclear proteins that replace histones late in the haploid phase of spermatogenesis and are believed essential for sperm head condensation and DNA stabilization, as for the chemical structure: There is not one available. Could you be asking for something else? Answered by Lanita Fangman 2 years ago.

Protamine Sulfate Structure Answered by Fatimah Navor 2 years ago.

I agree with Pureology and Aveda, but personally, I find them to be way too expensive, with Pureology being about as high end as it gets (with Kerastase and Sisley). A cheaper alternative would be Burt's Bees. They have tons of formulas, and even tell how much % natural the products are on them. Answered by Grover Odums 2 years ago.

originalsmartie has answered your question and you should award her full 10 points. There is no chemical structure. There is no diagram. Answered by Quinton Gan 2 years ago.


Why is protamine sulfate injected at the end of dialysis?
Homework help! And if so why is it injected in the venous tube and not the arterial tube? -Thanks! Asked by Beatrice Loskill 2 years ago.

People are given heparin, an IV blood thinner, during dialysis to avoid blood clotting. Protamine sulfate is heparin's antidote and will stop its effects. It goes in the venous circulation because that's the right direction (toward the heart). Answered by Aleshia Dumm 2 years ago.


Why is protamine sulfate injected in the venous tube and not the arterial tube?
During kidney dialysis, why is the protamine sulfate injected in the venous tube and not the arterial tube? Please help. Asked by Harlan Micheals 2 years ago.

I don't know Answered by Lance Boncella 2 years ago.


What would happen if you say gave a patient 10mg of protamine Sulfate?
Without 1000 active units of heparin in their body Asked by Fiona Puliafico 2 years ago.

Probably not much but you run the risk of pulmonary hypertension, systemic hypotension, pulmonary edema or an allergic reaction. Answered by Flor Grumbling 2 years ago.


The recommended antidote for a heparin overdose is?
Asked by Shara Bojanowski 2 years ago.

protamine sulphate will reverse anticoagulation of hep. Answered by Breana Kreb 2 years ago.

Antidote For Heparin Answered by Kimberly Kikkert 2 years ago.

Heparin Antidote Answered by Tomiko Kornprobst 2 years ago.

protamine sulfate Answered by Nilsa Manely 2 years ago.


You are delivering medications to the hospital floors when you hear a commotion.?
the nurse tells you that a bag of Heparin accidentally ran at 4 times the rate, and the patient is starting to bleed. immediately you pick up the phone to call the pharmacy. what medication will you ask the technician to get from the pharmacist, because the pt will require it soon? why? Asked by Mitchell Asevedo 2 years ago.

The answer is Protamine Sulfate, it is a heparin antagonist. Vitamin K is the antidote for a Warfarin (Coumadin) overdose. Answered by Alisa Shost 2 years ago.

Protamine Sulfate to stop the anti-coagulating effect .... and a double scotch for the stupid idiot who overdosed the patient. Makes getting fired easier to take. Answered by Alejandro Bukrim 2 years ago.

Protamine sulfate Answered by Elsy Kaleiwahea 2 years ago.

a coagulant,if the patient is bleeding then you need to staunch the flow of blood,also saisaline replace the lost fluids. Answered by Cornell Royle 2 years ago.

Its not your job, you can call make the call but the other floors need you to stock their rooms with meds sounds as if the nurse screwed up! Answered by Paula Stromyer 2 years ago.

intravenous vitamin K? Some thing that helps clot that is for sure Answered by Man Heady 2 years ago.

i agree with christelle the patiant is not getting enogh vitamin k Answered by Amal Furuya 2 years ago.


Blood clots?
is there a way to give someone blood clots in there heart i man is there anywya a human can do something to give people blood clots or help it start clotting? Asked by Arlene Jahnel 2 years ago.

Vitamin K does increase blood's propensity to clot, as does Protamine Sulfate. Shouldn't cause clots in your heart though. Air introduced into a vein via iv access could cause an embolism, but it would take more than what they show on TV ... I have been told by an ED doc that it would take AT LEAST a 10 mL bolus ... . Good luck on this. Answered by Sung Suthoff 2 years ago.

No, there is not. Answered by Clarinda Holling 2 years ago.


Does anyone know the chemical structure of protamine sulfate?
A diagram would be helpful. Any related information on protamine sulfate and its impurities and associated LC assay/impurity methods would be excellent. Asked by Magdalen Mottley 2 years ago.

I know that protamines are small, arginine-rich, nuclear proteins that replace histones late in the haploid phase of spermatogenesis and are believed essential for sperm head condensation and DNA stabilization, as for the chemical structure: There is not one available. Could you be asking for something else? Answered by Virgil Callins 2 years ago.

Protamine Sulfate Structure Answered by Judy Cooksley 2 years ago.

I agree with Pureology and Aveda, but personally, I find them to be way too expensive, with Pureology being about as high end as it gets (with Kerastase and Sisley). A cheaper alternative would be Burt's Bees. They have tons of formulas, and even tell how much % natural the products are on them. Answered by Beatrice Postert 2 years ago.

originalsmartie has answered your question and you should award her full 10 points. There is no chemical structure. There is no diagram. Answered by Daphne Oats 2 years ago.


Why is protamine sulfate injected at the end of dialysis?
Homework help! And if so why is it injected in the venous tube and not the arterial tube? -Thanks! Asked by Hilaria Lauritsen 2 years ago.

People are given heparin, an IV blood thinner, during dialysis to avoid blood clotting. Protamine sulfate is heparin's antidote and will stop its effects. It goes in the venous circulation because that's the right direction (toward the heart). Answered by Rosaline Vollbrecht 2 years ago.


Why is protamine sulfate injected in the venous tube and not the arterial tube?
During kidney dialysis, why is the protamine sulfate injected in the venous tube and not the arterial tube? Please help. Asked by Mertie Amweg 2 years ago.

I don't know Answered by Rachell Strege 2 years ago.


What would happen if you say gave a patient 10mg of protamine Sulfate?
Without 1000 active units of heparin in their body Asked by Prince Hortman 2 years ago.

Probably not much but you run the risk of pulmonary hypertension, systemic hypotension, pulmonary edema or an allergic reaction. Answered by Sana Gilberg 2 years ago.


The recommended antidote for a heparin overdose is?
Asked by Tamera Costanza 2 years ago.

protamine sulphate will reverse anticoagulation of hep. Answered by Tiesha Mordhorst 2 years ago.

Antidote For Heparin Answered by Susanna Dolberry 2 years ago.

Heparin Antidote Answered by Nancey Ayhens 2 years ago.

protamine sulfate Answered by Earlene Hunker 2 years ago.


You are delivering medications to the hospital floors when you hear a commotion.?
the nurse tells you that a bag of Heparin accidentally ran at 4 times the rate, and the patient is starting to bleed. immediately you pick up the phone to call the pharmacy. what medication will you ask the technician to get from the pharmacist, because the pt will require it soon? why? Asked by Dianne Fabio 2 years ago.

The answer is Protamine Sulfate, it is a heparin antagonist. Vitamin K is the antidote for a Warfarin (Coumadin) overdose. Answered by Helaine Adinolfi 2 years ago.

Protamine Sulfate to stop the anti-coagulating effect .... and a double scotch for the stupid idiot who overdosed the patient. Makes getting fired easier to take. Answered by Ivelisse Trucker 2 years ago.

Protamine sulfate Answered by Leroy Reger 2 years ago.

a coagulant,if the patient is bleeding then you need to staunch the flow of blood,also saisaline replace the lost fluids. Answered by Tawanda Lamay 2 years ago.

Its not your job, you can call make the call but the other floors need you to stock their rooms with meds sounds as if the nurse screwed up! Answered by Vasiliki Hurles 2 years ago.

intravenous vitamin K? Some thing that helps clot that is for sure Answered by Marvin Fruchter 2 years ago.

i agree with christelle the patiant is not getting enogh vitamin k Answered by Wendy Alexader 2 years ago.


Blood clots?
is there a way to give someone blood clots in there heart i man is there anywya a human can do something to give people blood clots or help it start clotting? Asked by Evelynn Chrestman 2 years ago.

Vitamin K does increase blood's propensity to clot, as does Protamine Sulfate. Shouldn't cause clots in your heart though. Air introduced into a vein via iv access could cause an embolism, but it would take more than what they show on TV ... I have been told by an ED doc that it would take AT LEAST a 10 mL bolus ... . Good luck on this. Answered by Alba Cocoran 2 years ago.

No, there is not. Answered by Maryalice Saxton 2 years ago.


Does anyone know the chemical structure of protamine sulfate?
A diagram would be helpful. Any related information on protamine sulfate and its impurities and associated LC assay/impurity methods would be excellent. Asked by Torrie Nerren 2 years ago.

I know that protamines are small, arginine-rich, nuclear proteins that replace histones late in the haploid phase of spermatogenesis and are believed essential for sperm head condensation and DNA stabilization, as for the chemical structure: There is not one available. Could you be asking for something else? Answered by Shery Maronge 2 years ago.

Protamine Sulfate Structure Answered by Eleanor Cagley 2 years ago.

I agree with Pureology and Aveda, but personally, I find them to be way too expensive, with Pureology being about as high end as it gets (with Kerastase and Sisley). A cheaper alternative would be Burt's Bees. They have tons of formulas, and even tell how much % natural the products are on them. Answered by Alanna Austria 2 years ago.

originalsmartie has answered your question and you should award her full 10 points. There is no chemical structure. There is no diagram. Answered by Chris Yocom 2 years ago.


Why is protamine sulfate injected at the end of dialysis?
Homework help! And if so why is it injected in the venous tube and not the arterial tube? -Thanks! Asked by Wilburn Stanganelli 2 years ago.

People are given heparin, an IV blood thinner, during dialysis to avoid blood clotting. Protamine sulfate is heparin's antidote and will stop its effects. It goes in the venous circulation because that's the right direction (toward the heart). Answered by Treasa Moede 2 years ago.


Why is protamine sulfate injected in the venous tube and not the arterial tube?
During kidney dialysis, why is the protamine sulfate injected in the venous tube and not the arterial tube? Please help. Asked by Aundrea Lepke 2 years ago.

I don't know Answered by Jeffery Stratis 2 years ago.


What would happen if you say gave a patient 10mg of protamine Sulfate?
Without 1000 active units of heparin in their body Asked by Margarite Wironen 2 years ago.

Probably not much but you run the risk of pulmonary hypertension, systemic hypotension, pulmonary edema or an allergic reaction. Answered by Kanisha Wertz 2 years ago.


The recommended antidote for a heparin overdose is?
Asked by Palmer Huesman 2 years ago.

protamine sulphate will reverse anticoagulation of hep. Answered by Elida Capoccia 2 years ago.

Antidote For Heparin Answered by Gaylene Bersamin 2 years ago.

Heparin Antidote Answered by Nathanial Agemy 2 years ago.

protamine sulfate Answered by Bertha Wuest 2 years ago.


You are delivering medications to the hospital floors when you hear a commotion.?
the nurse tells you that a bag of Heparin accidentally ran at 4 times the rate, and the patient is starting to bleed. immediately you pick up the phone to call the pharmacy. what medication will you ask the technician to get from the pharmacist, because the pt will require it soon? why? Asked by Liane Novelly 2 years ago.

The answer is Protamine Sulfate, it is a heparin antagonist. Vitamin K is the antidote for a Warfarin (Coumadin) overdose. Answered by Clarice Baughman 2 years ago.

Protamine Sulfate to stop the anti-coagulating effect .... and a double scotch for the stupid idiot who overdosed the patient. Makes getting fired easier to take. Answered by Troy Buress 2 years ago.

Protamine sulfate Answered by Elda Mikuszewski 2 years ago.

a coagulant,if the patient is bleeding then you need to staunch the flow of blood,also saisaline replace the lost fluids. Answered by Oliva Dollak 2 years ago.

Its not your job, you can call make the call but the other floors need you to stock their rooms with meds sounds as if the nurse screwed up! Answered by Denae Lecroy 2 years ago.

intravenous vitamin K? Some thing that helps clot that is for sure Answered by Nettie Stamp 2 years ago.

i agree with christelle the patiant is not getting enogh vitamin k Answered by Shalon Manzueta 2 years ago.


Blood clots?
is there a way to give someone blood clots in there heart i man is there anywya a human can do something to give people blood clots or help it start clotting? Asked by Lindsey Cabellon 2 years ago.

Vitamin K does increase blood's propensity to clot, as does Protamine Sulfate. Shouldn't cause clots in your heart though. Air introduced into a vein via iv access could cause an embolism, but it would take more than what they show on TV ... I have been told by an ED doc that it would take AT LEAST a 10 mL bolus ... . Good luck on this. Answered by Chere Herrman 2 years ago.

No, there is not. Answered by Lynette Weese 2 years ago.


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