Application Information

This drug has been submitted to the FDA under the reference 006188/001.

Names and composition

"PROPYLTHIOURACIL" is the commercial name of a drug composed of PROPYLTHIOURACIL.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
006188/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
006213/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080015/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080016/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080154/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080159/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080172/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080215/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080285/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080840/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080932/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
083982/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
084075/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
084543/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
085201/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
006188/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
006213/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080015/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080016/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080154/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080159/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080172/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080215/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080285/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080840/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
080932/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
083982/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
084075/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
084543/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG
085201/001 PROPYLTHIOURACIL PROPYLTHIOURACIL TABLET/ORAL 50MG

Ask a doctor

A licensed doctor will try to answer your question for free as quickly as possible. Free of charge during the beta period.

Answered questions

Side effect propylthiouracil 50 mg?
Asked by Alberto Birdtail 2 years ago.

Propylthiouracil Side Effects Major adverse reactions (much less common than the minor adverse reactions) include liver injury resulting in hepatitis, liver failure, a need for liver transplantation or death. Inhibition of myelopoiesis (agranulocytosis, granulopenia, and thrombocytopenia), aplastic anemia, drug fever, a lupus-like syndrome (including splenomegaly and vasculitis), hepatitis, periarteritis, and hypoprothrombinemia and bleeding have been reported. Nephritis, glomerulonephritis, interstitial pneumonitis, exfoliative dermatitis, and erythema nodosum have been reported. Reports of a vasculitis syndrome associated with the presence of anti-neutrophilic cytoplasmic antibodies (ANCA) have also been received. Manifestations of ANCA-positive vasculitis may include rapidly progressive glomerulonephritis (crescentic and pauci-immune necrotizing glomerulonephritis), sometimes leading to acute renal failure; pulmonary infiltrates or alveolar hemorrhage; skin ulcers; and leukocytoclastic vasculitis. Minor adverse reactions include skin rash, urticaria, nausea, vomiting, epigastric distress, arthralgia, paresthesias, loss of taste, taste perversion, abnormal loss of hair, myalgia, headache, pruritus, drowsiness, neuritis, edema, vertigo, skin pigmentation, jaundice, sialadenopathy, and lymphadenopathy. It should be noted that about 10% of patients with untreated hyperthyroidism have leukopenia (white blood cell count of less than 4,000/mm3 ), often with relative granulopenia. Answered by Glenna Infantolino 2 years ago.


(propylthiouracil) can this medications for over ative thyroids be dangerouse for pregnancy?
Ok so I have ben sick and throwing up for more than 5 weeks lost weight and doc says I have low protien level and over active thyroids and put me on medication for it and the meds are makeing me more sick and throwing up and since I've ben taking this medication I have ben haveing prety bad cramps and I was... Asked by Adan Dario 2 years ago.

Ok so I have ben sick and throwing up for more than 5 weeks lost weight and doc says I have low protien level and over active thyroids and put me on medication for it and the meds are makeing me more sick and throwing up and since I've ben taking this medication I have ben haveing prety bad cramps and I was wondering if this medication can be bad for my pregnancy and make me have a miscariage? I am 11 weeks pregnant! I know if the doc gave it to me it must be safe right? But they could be wrong or maybe its just not right for me I feel horrible on this medication Answered by Naida Turnblom 2 years ago.

Propylthiouracil can cause fetal harm when administered to a pregnant woman. Because the drug readily crosses placental membranes and can induce goiter and even cretinism in the developing fetus, it is important that a sufficient, but not excessive, dose be given. In many pregnant women, the thyroid dysfunction diminishes as the pregnancy proceeds; consequently, a reduction of dosage may be possible. In some instances, Propylthiouracil can be withdrawn 2 or 3 weeks before delivery. Answered by Rachelle Reddrick 2 years ago.


Why is propylthiouracil used to treat hyperthyroidism?
What is its effect on metabolic rate? Asked by Abbey Ballantyne 2 years ago.

Propylthiouracil, or PTU, actually suppresses thyroid hormone. It treats the hyperthyroidism directly, and it thereby slows metabolic rate. It is used despite the high rate of side effects because it causes a remission of Grave's disease about half of the time and so about half of people with Grave's diseases who use it, can go off of it and need no further treatment. Answered by Nubia Guard 2 years ago.


Taking propylthiouracil for enlarged and overactive thyroid?
I was diagonsed with slightly enlarged thyroid and was send to a specialist and given propylthiouracil in the mean time. I started taking it a week ago and have seen improvement on my symptoms, but I now have a sore throat. The patient information sheet that came with the medicine said that this meds can cuase... Asked by Clara Nicolia 2 years ago.

I was diagonsed with slightly enlarged thyroid and was send to a specialist and given propylthiouracil in the mean time. I started taking it a week ago and have seen improvement on my symptoms, but I now have a sore throat. The patient information sheet that came with the medicine said that this meds can cuase low white blood cell development in the patient. Can my sore throat be more than a simple sore throat/cold thing? I call the dr's office and they said it can't be the meds becuase I have been on them for a week already, that the symptoms would have shown like in three days. Any help out there...I am freaked out.... Answered by Carlena Achin 2 years ago.

Propylthiouracil can cause swelling of the lymph nodes which can cause a sore throat. However symptoms usually become evident in the first few days of taking the medication. If your syptoms developed a week later it is likely that you simply have a sore throat, flu, or cold. Low white blood cell count would not result in a sore throat and I'd say you have little to worry about. Answered by Elwood Hasychak 2 years ago.

I take a different thyroid medicine but when i first started on them i got a sore throat all the time. It will probably go on for a few weeks sucks i know just watch out for your health and drink a lot of warm things. They should go away and level off later on. Oh thyroid problems you're so great. also watch out for those white blood cells. if you get reoccurring infections get your white blood cells counted too Answered by Roy Evanchalk 2 years ago.

The low white blood cell count wouldn't cause the sore throat, but it might delay the healing time of it, since white blood cells are part of the body's defense system. Answered by Josefina Murano 2 years ago.


My mother accidentally swallowed a Propylthiouracil pill, is this dangerous?
my mother confused my father's pills with hers and took a propylthiouracil pill accidentally, and we're not sure if we should worry about it or not, is it dangerous or something? Asked by Delfina Spada 2 years ago.

Propylthiouracil is used to tread hyperthyroidism and is not dangerous in small doses. Most people who take PropylthiouracilI have to take it 3 times a day (every 8 hours) to get the full effect, so if your mother only took one pill, she will be fine. Answered by Ali Grammer 2 years ago.

Call your father's doctor or the poison control center: 1-800-222-1222 Answered by Domingo Broadwater 2 years ago.

one tablet of PTU is not going to kill your mom. however, observe her if she has any unusual symptoms. not to worry though! dr pham Answered by Lidia Broyhill 2 years ago.


Has anyone personally had a bad experience with propylthiouracil (PTU)??
Asked by Rashad Wildermuth 2 years ago.

Yes. I didn't like the side effects--sluggishness, weight gain to name a few. I was told by my primary care physician as well as my endocrinolgist that long-term use of PTU was not good as it could cause muscle weakness among other things. They finally convinced me to have radioactive iodine therapy for my Grave's Disease. No more PTU, just a lifetime of thyroid meds and routine blood tests. Answered by Sonja Spalla 2 years ago.


Hyperthyroidism / Propylthiouracil?
Here's my question, I was diagnosed with hyperthyroidism 4 years ago, i was told to take 13 every 8 hours. 39 a day. since thenI only take 13 a day mostly. i forget about it most of the time.they work OK, but still don't fix my problem. so how bad are this pills for me? any symptoms i should be... Asked by Alyse Logins 2 years ago.

Here's my question, I was diagnosed with hyperthyroidism 4 years ago, i was told to take 13 every 8 hours. 39 a day. since then I only take 13 a day mostly. i forget about it most of the time. they work OK, but still don't fix my problem. so how bad are this pills for me? any symptoms i should be aware of? i heard they cause liver failure and kill people. i have been having a pain on the right upper part of my stomach is it my liver acting up? please help. thanks. Answered by Sandie Ehli 2 years ago.

Your doctor should do liver tests to check your liver: 1. the liver enzymes will give the doctor an idea if there is liver cell damage 2 the liver function tests will give the doctor an idea how well your cells are about to perform functions, that the liver does as whole, to keep the body well. 3 the liver viral tests to see if a virus is using your liver cells to replicate itself. The doctor has to weigh the pros and cons of all medications that are used. If he believes there is a liver/biliary problem, he may refer you to a gastroenterologist and they both should work together to decide what medications you are to take and the dosage. They may do an ultrasound to see if the liver has enlarged due to inflammation. The thyroid produces a hormone, Thyroxine, which controls the metabolism. The liver is the organ that does most of the metabolizing. I hope this info is of some help. Best wishes Answered by Jeffie Berkley 2 years ago.


Effects of propylthiouracil on a normal rat?
why would less O2 be consumed, metabolic rate be decreased, and mass be formed if propylthiouracil injected to a normal rat? Asked by Tiffaney Lunt 2 years ago.

Because it decreases the amount of thyroid hormone produced by the thyroid. The thyroid controls how quickly the body uses energy, makes proteins, and controls how sensitive the body is to other hormones. Answered by Cinthia Wilkus 2 years ago.


Propylthiouracil on pregnant woman?!?
I suffering from hyperthyroidism. And my doctor suggest me to take PROPYLTHOURACIL. Well is this safe?! I read on some articles. "That There is evidence that PTU may cause harm to the fetus during pregnancy." thou it follows "PTU may be considered useful under physician supervision." I'm... Asked by Mallory Paduano 2 years ago.

I suffering from hyperthyroidism. And my doctor suggest me to take PROPYLTHOURACIL. Well is this safe?! I read on some articles. "That There is evidence that PTU may cause harm to the fetus during pregnancy." thou it follows "PTU may be considered useful under physician supervision." I'm just worried about my baby, i need your suggestions. Thanks! =) Answered by Sook Ruppe 2 years ago.

if your doctor told you to take it knowing you are pregnant, he obviously knows the risks already... theres obviously a bigger risk to you and your baby if you DONT take the medication.. id def either get a second opinion or just do what the doc says Answered by Collene Nibbs 2 years ago.

PREGNANCY and BREAST-FEEDING: Propylthiouracil has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Propylthiouracil while you are pregnant. Propylthiouracil is found in breast milk. Do not breast-feed while taking Propylthiouracil . This is all i could find on it. Id call your dr and ask questions. Answered by Lanny Housley 2 years ago.

If you're concerned about this, I'd get a second medical opinion...not a Yahoo opinion to back this up... Answered by Suzanna Dominski 2 years ago.


Side effect propylthiouracil 50 mg?
Asked by Isabell Jacome 2 years ago.

Propylthiouracil Side Effects Major adverse reactions (much less common than the minor adverse reactions) include liver injury resulting in hepatitis, liver failure, a need for liver transplantation or death. Inhibition of myelopoiesis (agranulocytosis, granulopenia, and thrombocytopenia), aplastic anemia, drug fever, a lupus-like syndrome (including splenomegaly and vasculitis), hepatitis, periarteritis, and hypoprothrombinemia and bleeding have been reported. Nephritis, glomerulonephritis, interstitial pneumonitis, exfoliative dermatitis, and erythema nodosum have been reported. Reports of a vasculitis syndrome associated with the presence of anti-neutrophilic cytoplasmic antibodies (ANCA) have also been received. Manifestations of ANCA-positive vasculitis may include rapidly progressive glomerulonephritis (crescentic and pauci-immune necrotizing glomerulonephritis), sometimes leading to acute renal failure; pulmonary infiltrates or alveolar hemorrhage; skin ulcers; and leukocytoclastic vasculitis. Minor adverse reactions include skin rash, urticaria, nausea, vomiting, epigastric distress, arthralgia, paresthesias, loss of taste, taste perversion, abnormal loss of hair, myalgia, headache, pruritus, drowsiness, neuritis, edema, vertigo, skin pigmentation, jaundice, sialadenopathy, and lymphadenopathy. It should be noted that about 10% of patients with untreated hyperthyroidism have leukopenia (white blood cell count of less than 4,000/mm3 ), often with relative granulopenia. Answered by Lonnie Kranzler 2 years ago.


(propylthiouracil) can this medications for over ative thyroids be dangerouse for pregnancy?
Ok so I have ben sick and throwing up for more than 5 weeks lost weight and doc says I have low protien level and over active thyroids and put me on medication for it and the meds are makeing me more sick and throwing up and since I've ben taking this medication I have ben haveing prety bad cramps and I was... Asked by Clay Claman 2 years ago.

Ok so I have ben sick and throwing up for more than 5 weeks lost weight and doc says I have low protien level and over active thyroids and put me on medication for it and the meds are makeing me more sick and throwing up and since I've ben taking this medication I have ben haveing prety bad cramps and I was wondering if this medication can be bad for my pregnancy and make me have a miscariage? I am 11 weeks pregnant! I know if the doc gave it to me it must be safe right? But they could be wrong or maybe its just not right for me I feel horrible on this medication Answered by Lashon Lafontant 2 years ago.

Propylthiouracil can cause fetal harm when administered to a pregnant woman. Because the drug readily crosses placental membranes and can induce goiter and even cretinism in the developing fetus, it is important that a sufficient, but not excessive, dose be given. In many pregnant women, the thyroid dysfunction diminishes as the pregnancy proceeds; consequently, a reduction of dosage may be possible. In some instances, Propylthiouracil can be withdrawn 2 or 3 weeks before delivery. Answered by Breanne Lanphear 2 years ago.


Why is propylthiouracil used to treat hyperthyroidism?
What is its effect on metabolic rate? Asked by Pamella Ferrebee 2 years ago.

Propylthiouracil, or PTU, actually suppresses thyroid hormone. It treats the hyperthyroidism directly, and it thereby slows metabolic rate. It is used despite the high rate of side effects because it causes a remission of Grave's disease about half of the time and so about half of people with Grave's diseases who use it, can go off of it and need no further treatment. Answered by Adrian Brandl 2 years ago.


Taking propylthiouracil for enlarged and overactive thyroid?
I was diagonsed with slightly enlarged thyroid and was send to a specialist and given propylthiouracil in the mean time. I started taking it a week ago and have seen improvement on my symptoms, but I now have a sore throat. The patient information sheet that came with the medicine said that this meds can cuase... Asked by Cornelia Gacia 2 years ago.

I was diagonsed with slightly enlarged thyroid and was send to a specialist and given propylthiouracil in the mean time. I started taking it a week ago and have seen improvement on my symptoms, but I now have a sore throat. The patient information sheet that came with the medicine said that this meds can cuase low white blood cell development in the patient. Can my sore throat be more than a simple sore throat/cold thing? I call the dr's office and they said it can't be the meds becuase I have been on them for a week already, that the symptoms would have shown like in three days. Any help out there...I am freaked out.... Answered by Miyoko Blumenstein 2 years ago.

Propylthiouracil can cause swelling of the lymph nodes which can cause a sore throat. However symptoms usually become evident in the first few days of taking the medication. If your syptoms developed a week later it is likely that you simply have a sore throat, flu, or cold. Low white blood cell count would not result in a sore throat and I'd say you have little to worry about. Answered by Val Pruskowski 2 years ago.

I take a different thyroid medicine but when i first started on them i got a sore throat all the time. It will probably go on for a few weeks sucks i know just watch out for your health and drink a lot of warm things. They should go away and level off later on. Oh thyroid problems you're so great. also watch out for those white blood cells. if you get reoccurring infections get your white blood cells counted too Answered by Elanor Gennette 2 years ago.

The low white blood cell count wouldn't cause the sore throat, but it might delay the healing time of it, since white blood cells are part of the body's defense system. Answered by Lindsey Trethewey 2 years ago.


My mother accidentally swallowed a Propylthiouracil pill, is this dangerous?
my mother confused my father's pills with hers and took a propylthiouracil pill accidentally, and we're not sure if we should worry about it or not, is it dangerous or something? Asked by Roy Canham 2 years ago.

Propylthiouracil is used to tread hyperthyroidism and is not dangerous in small doses. Most people who take PropylthiouracilI have to take it 3 times a day (every 8 hours) to get the full effect, so if your mother only took one pill, she will be fine. Answered by Ahmed Stace 2 years ago.

Call your father's doctor or the poison control center: 1-800-222-1222 Answered by Tegan Waskin 2 years ago.

one tablet of PTU is not going to kill your mom. however, observe her if she has any unusual symptoms. not to worry though! dr pham Answered by Vonnie Cabreros 2 years ago.


Has anyone personally had a bad experience with propylthiouracil (PTU)??
Asked by Perry Maule 2 years ago.

Yes. I didn't like the side effects--sluggishness, weight gain to name a few. I was told by my primary care physician as well as my endocrinolgist that long-term use of PTU was not good as it could cause muscle weakness among other things. They finally convinced me to have radioactive iodine therapy for my Grave's Disease. No more PTU, just a lifetime of thyroid meds and routine blood tests. Answered by Deana Szczeblewski 2 years ago.


Hyperthyroidism / Propylthiouracil?
Here's my question, I was diagnosed with hyperthyroidism 4 years ago, i was told to take 13 every 8 hours. 39 a day. since thenI only take 13 a day mostly. i forget about it most of the time.they work OK, but still don't fix my problem. so how bad are this pills for me? any symptoms i should be... Asked by Tammera Halloway 2 years ago.

Here's my question, I was diagnosed with hyperthyroidism 4 years ago, i was told to take 13 every 8 hours. 39 a day. since then I only take 13 a day mostly. i forget about it most of the time. they work OK, but still don't fix my problem. so how bad are this pills for me? any symptoms i should be aware of? i heard they cause liver failure and kill people. i have been having a pain on the right upper part of my stomach is it my liver acting up? please help. thanks. Answered by Keisha Letterlough 2 years ago.

Your doctor should do liver tests to check your liver: 1. the liver enzymes will give the doctor an idea if there is liver cell damage 2 the liver function tests will give the doctor an idea how well your cells are about to perform functions, that the liver does as whole, to keep the body well. 3 the liver viral tests to see if a virus is using your liver cells to replicate itself. The doctor has to weigh the pros and cons of all medications that are used. If he believes there is a liver/biliary problem, he may refer you to a gastroenterologist and they both should work together to decide what medications you are to take and the dosage. They may do an ultrasound to see if the liver has enlarged due to inflammation. The thyroid produces a hormone, Thyroxine, which controls the metabolism. The liver is the organ that does most of the metabolizing. I hope this info is of some help. Best wishes Answered by Jamal Scheyer 2 years ago.


Effects of propylthiouracil on a normal rat?
why would less O2 be consumed, metabolic rate be decreased, and mass be formed if propylthiouracil injected to a normal rat? Asked by Lai Kadlec 2 years ago.

Because it decreases the amount of thyroid hormone produced by the thyroid. The thyroid controls how quickly the body uses energy, makes proteins, and controls how sensitive the body is to other hormones. Answered by Cathryn Kogel 2 years ago.


Propylthiouracil on pregnant woman?!?
I suffering from hyperthyroidism. And my doctor suggest me to take PROPYLTHOURACIL. Well is this safe?! I read on some articles. "That There is evidence that PTU may cause harm to the fetus during pregnancy." thou it follows "PTU may be considered useful under physician supervision." I'm... Asked by Jeremy Caplette 2 years ago.

I suffering from hyperthyroidism. And my doctor suggest me to take PROPYLTHOURACIL. Well is this safe?! I read on some articles. "That There is evidence that PTU may cause harm to the fetus during pregnancy." thou it follows "PTU may be considered useful under physician supervision." I'm just worried about my baby, i need your suggestions. Thanks! =) Answered by Beatrice Dziurawiec 2 years ago.

if your doctor told you to take it knowing you are pregnant, he obviously knows the risks already... theres obviously a bigger risk to you and your baby if you DONT take the medication.. id def either get a second opinion or just do what the doc says Answered by Omar Knesel 2 years ago.

PREGNANCY and BREAST-FEEDING: Propylthiouracil has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Propylthiouracil while you are pregnant. Propylthiouracil is found in breast milk. Do not breast-feed while taking Propylthiouracil . This is all i could find on it. Id call your dr and ask questions. Answered by Merrilee Deus 2 years ago.

If you're concerned about this, I'd get a second medical opinion...not a Yahoo opinion to back this up... Answered by Mozell Rabenold 2 years ago.


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