PROGRAF Ressources

Application Information

This drug has been submitted to the FDA under the reference 050708/001.

Names and composition

"PROGRAF" is the commercial name of a drug composed of TACROLIMUS.
It belongs to the class Immunosuppressants and is used in Organ transplantation (Infections and Infestations)

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
050708/001 PROGRAF TACROLIMUS CAPSULE/ORAL EQ 1MG BASE
050708/002 PROGRAF TACROLIMUS CAPSULE/ORAL EQ 5MG BASE
050708/003 PROGRAF TACROLIMUS CAPSULE/ORAL EQ 0.5MG BASE
050709/001 PROGRAF TACROLIMUS INJECTABLE/INJECTION EQ 5MG BASE per ML

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
206406/002 ENVARSUS XR TACROLIMUS TABLET, EXTENDED RELEASE/ORAL EQ 1MG BASE
206406/003 ENVARSUS XR TACROLIMUS TABLET, EXTENDED RELEASE/ORAL EQ 4MG BASE
206406/001 ENVARSUS XR TACROLIMUS TABLET, EXTENDED RELEASE/ORAL EQ 0.75MG BASE
204096/003 ASTAGRAF XL TACROLIMUS CAPSULE, EXTENDED RELEASE/ORAL EQ 5MG BASE
204096/001 ASTAGRAF XL TACROLIMUS CAPSULE, EXTENDED RELEASE/ORAL EQ 0.5MG BASE
204096/002 ASTAGRAF XL TACROLIMUS CAPSULE, EXTENDED RELEASE/ORAL EQ 1MG BASE
050708/001 PROGRAF TACROLIMUS CAPSULE/ORAL EQ 1MG BASE
050708/002 PROGRAF TACROLIMUS CAPSULE/ORAL EQ 5MG BASE
050777/001 PROTOPIC TACROLIMUS OINTMENT/TOPICAL 0.03%
050708/003 PROGRAF TACROLIMUS CAPSULE/ORAL EQ 0.5MG BASE
050777/002 PROTOPIC TACROLIMUS OINTMENT/TOPICAL 0.1%
050709/001 PROGRAF TACROLIMUS INJECTABLE/INJECTION EQ 5MG BASE per ML
090402/001 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 5MG BASE
090509/001 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 0.5MG BASE
090509/002 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 1MG BASE
090509/003 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 5MG BASE
090596/001 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 0.5MG BASE
090596/002 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 1MG BASE
090596/003 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 5MG BASE
090687/001 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 0.5MG BASE
090687/002 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 1MG BASE
090687/003 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 5MG BASE
090802/001 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 0.5MG BASE
090802/002 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 1MG BASE
090802/003 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 5MG BASE
091195/001 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 0.5MG BASE
091195/002 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 1MG BASE
091195/003 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 5MG BASE
200744/001 TACROLIMUS TACROLIMUS OINTMENT/TOPICAL 0.03%
200744/002 TACROLIMUS TACROLIMUS OINTMENT/TOPICAL 0.1%
065461/001 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 0.5MG BASE
065461/002 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 1MG BASE
065461/003 TACROLIMUS TACROLIMUS CAPSULE/ORAL EQ 5MG BASE

Manufacturers

Manufacturer name
Astellas Pharma Ltd

Ask a question

A licensed doctor will try to answer your question as quickly as possible.

Answered questions

The effects of prograf pill after many years???
My mom has been taking Prograf for 12 years because of a liver transplant. What would be the effects physically after taking it for many years? Dose anybody know? Asked by Deonna Kudro 1 month ago.

Using Prograf may increase your risk of developing certain types of cancer, especially skin cancer. The risk may be higher in people who are treated over long periods of time with drugs that weaken the immune system. Talk with your doctor about your individual risk. Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun. To be sure this medication is not causing harmful effects, your blood will need to be tested on a regular basis. Your kidney or liver function may also need to be tested. It is important that you not miss any scheduled visits to your doctor. Your mum's doctor will determine whether it is safer to take the drug (and not reject the liver - she can't live without one) and be watchful for adverse effects or cease the drug and lose the liver. Most people do pretty well and after 12 years seems your mum is one of those that does well. Answered by Armanda Mccorkindale 1 month ago.

Prograf causes severe nerve pain. I'm on Prograf because I had a kidney transplant 3.5 years ago. My hands and feet would burn so bad, it would hurt enough to remind me that I don't wanna be burned with fire. As bad as that is, I imagine fire would be a lot worse. Answered by Kermit Hunton 1 month ago.


What can I do with my Tacrolimus (prograf) medication? can I sell them?
Hi, I had a liver Transplant 12 years ago and I was on Tacrolimus for last 12 years. due my my kidneys complications yesterday doctors change it to other immune suppressive called Sirolimus. But I recently bought lots of Tacrolimus. where can I sell them if it is possible at all. (obviously much cheaper than normal... Asked by Aida Kuhta 1 month ago.

Hi, I had a liver Transplant 12 years ago and I was on Tacrolimus for last 12 years. due my my kidneys complications yesterday doctors change it to other immune suppressive called Sirolimus. But I recently bought lots of Tacrolimus. where can I sell them if it is possible at all. (obviously much cheaper than normal price). If I give it back to pharmacy they will dispose it, I asked about it. they all in original pack and not open and kept in the right condition. Many thanks. Answered by Gretchen Zabik 1 month ago.

I'm really not sure, but I doubt that it would be legal to sell your Prograf to anyone. It's a prescription drug that must be ordered by a doctor, so I think that is going to really limit your options for selling it. If you want someone to benefit from it instead of it being destroyed, maybe you could give it to a transplant clinic where they might be able to give it to someone that could use it. I know when I had a drug that I no longer took and it was still all new and packaged, I gave it to the local free clinic. They really appreciated it and gave it to their patients that had no insurance and could really use the help. Since Prograf is used only for transplants, I would think someone at a transplant clinic could use it. Answered by Roscoe Lathan 1 month ago.


Can Prograf cause Tinnadus as a side effect?
I have been taking a very low dosage of Prograf (2mg)ever since my heart transplant and have always had a ringing in my ears when outside sound isnt there. Is it Tinnadus? I've always had it but have just started to really notice it. Anything I can do? Talk to my doctor or..... Asked by Shaquana Shewmake 1 month ago.

Tinnitus is associated with the use of Prograf. There are many other medications that can cause tinnitus, such as Aspirin in high doses, aminoglycoside antibiotics and high doses of loop diuretics like Furosemide. I don't know your other medications, but they should also be reviewed. Several medical conditions are also associated with tinnitus. Let your heart transplant doctor know this. You may need hearing testing and evaluation by an Otolarynologist. Good luck. Answered by Alex Boris 1 month ago.

man made drugs are created for particular purposes, regardless of the indisputable fact that it is impossible to foretell precisely what's going to happen throughout something of the physique. organic remedies are composed of fabrics that have co-existed in this earth with us via our evolution for some years. Synthetics have not been around very long in any respect, in assessment. organic remedies have form of "have been given the kinks worked out" and are effective in a manner that does the main stable jointly as doing the least harm. Synthetics reason factor consequences hence of being partly rejected with the help of the physique (Nausea, diarrhea, vomiting, dryness, etc.) Answered by Marivel Deardorff 1 month ago.

One of the side effects of this drug is hearing abnormalities. I'd go see the doctor - just be safe Answered by Alba Colby 1 month ago.

Tinnitis is listed as a side effect talk you your cardiologist Answered by Elvera Roelle 1 month ago.


For post kidney transplants, what is your dose of Prograf?
I am just curious as to what people are taking of Prograf. My dosage changes often. My transplant team says this is normal. I am just curious as to what other people are taking. Mine seems to change according to how much Cellcept I take also. My stomach is very sensitive to the Cellcept. I'm having all sorts of... Asked by Santiago Upole 1 month ago.

I am just curious as to what people are taking of Prograf. My dosage changes often. My transplant team says this is normal. I am just curious as to what other people are taking. Mine seems to change according to how much Cellcept I take also. My stomach is very sensitive to the Cellcept. I'm having all sorts of stomach and intestinal problems on it, so they are cutting my dosage down on that. The less Cellcept I take, the higher my Prograf dosage seems to go up. Just curious.. Thanks! Answered by Myrta Gercak 1 month ago.

my brother is a kidney trasplant patient too.. he's taking cellcept and neoral.. i have not heard of prograf. the dosages of the drugs are calculated on how much you weigh.. i think the reason why they advised you to take a higher dose of prograf is to compensate for the lowered dose of your cellcept. Answered by Louetta Manoni 1 month ago.


Will lisinopril interfere with prograf organ rejection medication?
im wondering if i can take this with prograf Asked by Margorie Hind 1 month ago.

They don't interact however they can be detrimental together if you have any kidney impairment so monitoring of your kidney function and electrolytes may need to be done periodically. To the previous poster who mentioned taking one of these meds during pregnancy I hope you were referring to the Prograf because lisinopril is an ACE inhibitor and is contraindicated in pregnancy as it is known to cause fetal death. Answered by Erich Railey 1 month ago.

No it wont, but it has nothing to do with taking it while being pregnant. Answered by Ivana Refsell 1 month ago.

not at all. i took it while i was pregnant Answered by Rashad Roerig 1 month ago.


Hello what does SK mean? Context:SK level elevation caused by Prograf?
This is abroader context: In regards to her right lung transplant for COPD, her SK level was elevated during her hospital stay. Her Prograf dose was reduced. However, on the day of discharge, her SK level was still 26. She was instructed not to take any more Prograf today and to decrease her doseThank you Asked by Cuc Ludgate 1 month ago.

This is abroader context: In regards to her right lung transplant for COPD, her SK level was elevated during her hospital stay. Her Prograf dose was reduced. However, on the day of discharge, her SK level was still 26. She was instructed not to take any more Prograf today and to decrease her dose Thank you Answered by Maren Hothan 1 month ago.

I think you mean FK, not SK. Prograf has a generic name, FK506. So we usually will get levels to decide how much to dose. Normal levels 10-20, so 26 would require a lower dose. Answered by Ricarda Pillai 1 month ago.


My dad overdose on Prograf?? help?
hi my dad is 62 years old and accidently he overdose on prograf by taking 4 bills in just 1 hour?? what will happen to him Asked by Karry Orloski 1 month ago.

Insure he visits a hospital as quickly as possible. Too much prograf can wreck your immune system and can cause kidney problems. Answered by Coralee Drennon 1 month ago.

Prograf Overdose Answered by Louella Smyre 1 month ago.


Question about the medicine prograf ?
Will the immune suppresuve drug prograf give me cancer is their a higher risk in liver transplants and if soo what types of cancers are they deadly Asked by Margurite Callon 1 month ago.

The drug won't give you cancer. It MIGHT allow a cancer to develop. Talk to your transplant or GI doc. Answered by Harriet Weinmann 1 month ago.

Prograf, a drug commonly known as Tacrolimus, used to suppress patient’s immune system after an organ transplant. The drug lowers the activity of the patient’s immune system and as a result brings down the chances of rejection of the organ. This is because your immune system helps your body fight viruses. It will treat a transplanted organ, such as the liver or the kidney, as an invader and reject the same. Prograf is normally used in modern preparations of medicines to treat conditions such as severe dermatitis or eczema, vitiligo of the skin or refractory uveitis after a bone marrow transplant. Answered by Piper Habegger 1 month ago.


Anyone interested in Tacrolimus, Prograf ?
Dear readers, My mom takes Tacrolimus, Prograf, and recently her doctor lowered her dose , and she does not need that much anymore. If anyone interested I would like to give it very very cheap plus little shipping charge, they are in original pack directly from factory. please contact [email protected] Asked by Rena Hidinger 1 month ago.

Nah, ...... not really. Answered by Luna Ruffini 1 month ago.


I need to buy Prograf without prescription?
Hi, Please suggest a store where can I order Prograf without prescription. Thanks! Asked by Celena Markgraf 1 month ago.

Tacrolimus is used along with other medications to prevent rejection (attack of a transplanted organ by the immune system of a person receiving the organ) in people who have received kidney, liver, or heart transplants. Tacrolimus is in a class of medications called immunosupressants. It works by decreasing the activity of the immune system to prevent it from attacking the transplanted organ. It is also used in a topical preparation in the treatment of atopic dermatitis (eczema), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, and the skin condition vitiligo. IMPORTANT WARNING:-- Tacrolimus should only be given under the supervision of a doctor who is experienced in treating people who have had an organ transplant and in prescribing medications that decrease the activity of the immune system. Tacrolimus decreases the activity of your immune system. This may increase the risk that you will get a serious infection. If you experience any of the following symptoms, call your doctor immediately: sore throat; cough; fever; extreme tiredness; flu-like symptoms; warm, red, or painful skin; or other signs of infection. When your immune system is not working normally, there may be a greater risk that you will develop cancer, especially lymphoma (a type of cancer that begins in the cells of the immune system). The longer you take tacrolimus or other medications that decrease the activity of the immune system, and the higher your doses of these medications, the more this risk may increase. If you experience any of the following symptoms of lymphoma, call your doctor immediately: swollen lymph nodes in the neck, armpits, or groin; weight loss; fever; night sweats; excessive tiredness or weakness; cough; trouble breathing; chest pain; or pain, swelling, or fullness in the stomach area. Answered by Carleen Corrion 1 month ago.

Ranitidine is available both over the counter and on prescription, so if that's what you have then you can buy some in the pharmacy. But if it's a PPI that you're taking (Omeprazole, Lansoprazole etc.), they're only available on prescription. If I were you, I'd get some Ranitidine or some of the anti-reflux liquids to tide you over for the next few days. Answered by Delma Hassick 1 month ago.


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