Application Information

This drug has been submitted to the FDA under the reference 019898/002.

Names and composition

"PRAVACHOL" is the commercial name of a drug composed of PRAVASTATIN SODIUM.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
019898/002 PRAVACHOL PRAVASTATIN SODIUM TABLET/ORAL 10MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
019898/003 PRAVACHOL PRAVASTATIN SODIUM TABLET/ORAL 20MG
019898/004 PRAVACHOL PRAVASTATIN SODIUM TABLET/ORAL 40MG
019898/008 PRAVACHOL PRAVASTATIN SODIUM TABLET/ORAL 80MG

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
019898/002 PRAVACHOL PRAVASTATIN SODIUM TABLET/ORAL 10MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
019898/003 PRAVACHOL PRAVASTATIN SODIUM TABLET/ORAL 20MG
019898/004 PRAVACHOL PRAVASTATIN SODIUM TABLET/ORAL 40MG
019898/008 PRAVACHOL PRAVASTATIN SODIUM TABLET/ORAL 80MG
076056/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 10MG
076056/002 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 20MG
076056/003 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 40MG
076341/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 10MG
076341/002 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 20MG
076341/003 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 40MG
076341/004 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 80MG
076397/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 40MG
076397/002 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 20MG
076397/003 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 10MG
076445/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 10MG
076445/002 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 20MG
076445/003 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 40MG
076445/004 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 80MG
076714/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 10MG
076714/002 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 20MG
076714/003 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 40MG
076714/004 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 80MG
076939/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 80MG
076939/002 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 40MG
076939/003 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 20MG
076939/004 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 10MG
077013/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 10MG
077013/002 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 20MG
077013/003 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 40MG
077013/004 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 80MG
077491/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 80MG
077730/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 10MG
077730/002 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 20MG
077730/003 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 30MG
077730/004 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ ORAL 80MG
077730/005 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 40MG
077751/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 10MG
077751/002 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 20MG
077751/003 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 40MG
077751/004 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 80MG
077793/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 80MG
077904/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 10MG
077904/002 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 20MG
077904/003 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 40MG
077904/004 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 80MG
077917/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 10MG
077917/002 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 20MG
077917/003 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 40MG
077917/004 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 80MG
077987/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 10MG
077987/002 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 20MG
077987/003 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 40MG
077987/004 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 80MG
079187/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 10MG
079187/002 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 20MG
079187/003 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 40MG
079187/004 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 80MG
203367/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 10MG
203367/002 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 20MG
203367/003 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 40MG
203367/004 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 80MG
207068/001 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 10MG
207068/002 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 20MG
207068/003 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 40MG
207068/004 PRAVASTATIN SODIUM PRAVASTATIN SODIUM TABLET/ORAL 80MG

Ask a doctor

A licensed doctor will try to answer your question for free as quickly as possible. Free of charge during the beta period.

Answered questions

If Pravachol or Lipitor aren't working....?
He has been on these for YEARS!!! I wasn't worried too much about the 214 as much as the 445 and 11 numbers-they seem very lopsided. Thanks for your answer. Asked by Olympia Eachus 1 year ago.

will natural remedies have any effect of cholesterol? My Husband has been on both and his readings are sky high. 445 HDL and 11 LDL-- total 214. He works out, eats pretty well, no fast food, not over weight and am trying to figure out what to get naturally for him until we see the doctor again. I did buy flaxseed oil and garlic to start and am going to get the other things I have seen that are supposed to lower the numbers but if the prescriptions don't work is ANYTHING going to work? Answered by Marnie Mikez 1 year ago.

Pravachol (pravastatin sodium) and Lipitor (atorvastatin calcium) are very effective medications, but remember they're just pills, don't wait a miracle. He has to use them regularly for a couple of months. They will decrease and regulate the blood lipid levels. If they don't, talk to your doctor there are some similar mediacations like them, he/she may change them. 214mg/dl cholesterol is not a very high level, in fact according to some laboratories normal values are 120-240mg/dl. Just wait and don't panic. Those pills will help. Of course a healthy diet is important, but don't use some plants instead of medications, just keep your doctor's advices; and don't bore him too much. Answered by Dante Wiechert 1 year ago.


When can I get pravachol and niaspan generic?
I understand we have to wait 7 years before prescription RX can have a generic on the market.I don't know exactly when Pravachol and Niaspan first went on the market. I would like to find out when they would be eligible for generic. I have a donut hole on my Medicare Part D and this can make a difference... Asked by Emilia Sharpsteen 1 year ago.

I understand we have to wait 7 years before prescription RX can have a generic on the market. I don't know exactly when Pravachol and Niaspan first went on the market. I would like to find out when they would be eligible for generic. I have a donut hole on my Medicare Part D and this can make a difference as to whether I stay with my present carrier. Answered by Shad Andreason 1 year ago.

Pravachol does not yet have a generic counterpart and I cannot find out when one will be available, Niaspan however does have multiple generic brands available, go to your pharmacy and ask about Niacin Extended Release and they should be able to point one out. Hope this helps!! Answered by Darleen Gardenhire 1 year ago.


Is the PRAVACHOL ( pravastatin sodium ) lead compound or drived from a lead compound ?
well , I need also to know what is lead compound mean. if any body help me please!! Asked by Andrew Magallon 1 year ago.

The term lead compound is used in chemistry more as research terminology, I supose pravacol is modified from its original compound so it shouldn´t be a lead compound, read below. Pravastatin (marketed as Pravachol or Selektine) is a member of the drug class of statins, used for lowering cholesterol and preventing cardiovascular disease. Initially known as CS-514, it was originally identified in a bacterium called Nocardia autotrophica by researchers of the Sankyo Pharma Inc..It is presently being marketed outside Japan by the pharmaceutical company Bristol-Myers Squibb. A lead compound (i.e. the "leading" compound, not lead metal) in drug discovery is a chemical compound that has pharmacological or biological activity and whose chemical structure is used as a starting point for chemical modifications in order to improve potency, selectivity, or pharmacokinetic parameters. Answered by Carolin Tomsick 1 year ago.


Pravachol is produced by ?
Asked by Dorene Rudd 1 year ago.

Pravachol is produced Bristol-Myers Squibb Answered by Twyla Romon 1 year ago.

It's made from red rice yeast extract Answered by Gilberto Lachermeier 1 year ago.


Can pravachol and lipitor be taken together?
My husbands dr. has put him on pravachol and now wants him to take lipitor with it. She has not tried to put him on a diet of any kind. He also has an enlarged heart. Asked by Florencia Polston 1 year ago.

These meds are ok and will work fine together. Though he needs not to drink grapefruit juice with the liptor. It will elevate the level of the drug. With both of these drugs don't take the herbs eucalyoptus, jin bu huan, kava or red yeast rice. They will increase risk of hepatotoxicity and adverse reactions. Answered by Adena Withfield 1 year ago.

Both poison the same system by the same means. I can not believe any doctor would prescribe both. I consider both to be deadly poison. They damage muscle tissue and are known to damage the heart leading to congestive heart failure that leads to an enlarged heart. Pharmacist for 30 years who's life was almost ruined by Lipitor. Answered by Ophelia Cyr 1 year ago.

You know, the saddest part of what "healthcare" has become, is that doctors are no longer interested in healing anybody. Only in how much money they can make. They have become pawns of drug manufacturers, merely legal drug-pushers that kill thousands of people every year. There is not one single drug on the market that cures anything. Drugs merely address symptoms.Every prescription and non-prescription drug made causes illnesses and diseases. Most times, the side effects of a drug are much worse than what the drug is being taken for, i.e., you will no longer have a stuffy nose, but you may have stomach cramps, and difficulty swallowing, etc. I think I will just suffer the stuffy nose, thank you. That is how the body builds up defenses to illnesses and allergies. By suffering through things like that. The body will heal itself. It needs no help, just no hindrances. God designed it that way. When a prescription drug kills thousands of people, the makers of that drug already knew that it would kill thousands. They approve it anyway. Too much money involved. There is a natural cure for almost everything, unless it has been allowed to go too far. Seek out healthcare practitioners that do not use drugs and surgery. Your health will thank you for it. Answered by Anisha Askew 1 year ago.

I agree with midnight crier to a certain extent. Some people do require medication for some diseases. He is right about doctors not curing people. Your husband should see a naturopath or holistic practitioner for a natural health program which may be more beneficial. If he is overweight he should be on a health and exercise program designed for him to improve his health. Answered by Clemente Drong 1 year ago.

No. They are virtually identical. He should ask about a "heart healthy diet". Contrary to the claims of some, statins are NOT dangerous for most patients. Any medicine can cause side effects, statins are no different. Answered by Kaylee Looney 1 year ago.

If the Dr prescribed them to take together then I would believe it to be ok.....if not sure....ask the pharamacist Answered by Amanda Overbay 1 year ago.


Statins (Lipitor, Zocor, Mevacor, Pravachol, Crestor) are the number one selling drug in our country....?
Statins (Lipitor, Zocor, Mevacor, Pravachol, Crestor) are the number one selling drug in our country. Currently, 11 million people are taking a statin drug. The current national lipid guidelines estimate that 36 million people should actually be taking statins. How do statins reduce the risk of cardiovascular... Asked by Frederica Eichenberg 1 year ago.

Statins (Lipitor, Zocor, Mevacor, Pravachol, Crestor) are the number one selling drug in our country. Currently, 11 million people are taking a statin drug. The current national lipid guidelines estimate that 36 million people should actually be taking statins. How do statins reduce the risk of cardiovascular disease? stimulate production of HDL, which functions to remove excess cholesterol from cells stimulate production of LDL-cholesterol, reducing levels of free cholesterol in our blood stimulate the oxidation of LDL causes the exocytosis of cholesterol from cells; and stimulates cholesterol secretion into the intestine inhibit cholesterol synthesis; lowered cholesterol levels in cells induces the production of more LDL receptors Answered by Davis Notah 1 year ago.

Which would be the most beneficial? Think about this - don't just throw out an answer. What do statins do? I'll give you a hint - they have something to do with inhibiting enzymes in a biosynthetic pathway Answered by Azzie Abbot 1 year ago.

NO problem with Lipitor. Always check out the drug online for side effects. You utimately end up being responsible for yourself and only you know yourself. I did have a bad experience with a high blood pressure med. They thought I was having heart problems and order a very expensive cath. My arteries or veins were ok, all they needed to do was change that med. Always know the side effects and watch like crazy and do those tests every three months to check his liver. Good luck. And when they do blood work, I always ask for a copy. I put the results in a spread sheet and add each new set of tests. Sometimes you may be normal but there may be a general trend you want to see and it could take place over some time and you want to be aware of it and point it out to your doctor. And if they don't pay attention, get another one. Answered by Cori Eakes 1 year ago.


Why does pravachol have to be taken at bedtime?
i am awful about taking my pm meds...could i take the pravachol with morning meds ? Asked by Reuben Bagnall 1 year ago.

This is in a class of drugs known as statins and used for lowering cholesterol. From the research I've done this is a once daily dose. According to the manufacturer's read out pamphlet this doesn't specify a time. The reasoning for this would be because of interactions with other drugs you take too. Please refer this question to the doctor that prescribed it. You can also call your pharmacist tomorrow too. Allot of times they can also give you the answer because of the fact they fill all of your drugs and would know the answer to this too. Don't start taking this at any other time until you've gotten further advise regarding this. Good luck and God Bless Answered by Aliza Zenke 1 year ago.


What are the side effects of PRAVACHOL ?
I need the answer Asked by Maryanne Priess 1 year ago.

1)Patients with underlying liver disease may have increased serum transminase levels after consumptions and may have malaise , anorexia , precipitous decreases in LDL ( low density lipoprotein ) 2) Minor increases in creatine kinase activity in plasma are observed in some patients . Rarely patients may have marked elevations . If the drug is not discontinued , rhabdomyolysis may cause myoglobinuria leading to renal injury 3)Gastrointestinal side effects have been among the most common symptoms reported by patients on pravastatin. These symptoms tended to be mild and transient in nature and resolved with continued therapy. 4) Hematologic side effects including hemolytic anemia, thrombocytopenia, thrombotic thrombocytopenic purpura (TTP), and leukopenia have occurred with some HMG-CoA reductase inhibitors. These effects may be manifestations of a hypersensitivity reaction. 5)Nervous system side effects of pravastatin have included headache (0.6% to 6.2%), dizziness, drowsiness, and weakness. Cranial nerve dysfunction, tremor, vertigo, fatigue, weight loss, memory loss, decline in cognitive function, paresthesias, peripheral neuropathy, and peripheral nerve palsy have been reported with HMG-CoA reductase inhibitors. 6)Dermatologic side effects of pravastatin have included rash (0.9% to 4.0%) and a case report of bullous erythematous lesions. Erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, photosensitivity, purpura, and alopecia have occurred with HMG-CoA reductase inhibitors. Answered by Lena Demmons 1 year ago.


If Pravachol or Lipitor aren't working....?
He has been on these for YEARS!!! I wasn't worried too much about the 214 as much as the 445 and 11 numbers-they seem very lopsided. Thanks for your answer. Asked by Roy Rotty 1 year ago.

will natural remedies have any effect of cholesterol? My Husband has been on both and his readings are sky high. 445 HDL and 11 LDL-- total 214. He works out, eats pretty well, no fast food, not over weight and am trying to figure out what to get naturally for him until we see the doctor again. I did buy flaxseed oil and garlic to start and am going to get the other things I have seen that are supposed to lower the numbers but if the prescriptions don't work is ANYTHING going to work? Answered by Kathleen Judd 1 year ago.

Pravachol (pravastatin sodium) and Lipitor (atorvastatin calcium) are very effective medications, but remember they're just pills, don't wait a miracle. He has to use them regularly for a couple of months. They will decrease and regulate the blood lipid levels. If they don't, talk to your doctor there are some similar mediacations like them, he/she may change them. 214mg/dl cholesterol is not a very high level, in fact according to some laboratories normal values are 120-240mg/dl. Just wait and don't panic. Those pills will help. Of course a healthy diet is important, but don't use some plants instead of medications, just keep your doctor's advices; and don't bore him too much. Answered by Evalyn Muscara 1 year ago.


When can I get pravachol and niaspan generic?
I understand we have to wait 7 years before prescription RX can have a generic on the market.I don't know exactly when Pravachol and Niaspan first went on the market. I would like to find out when they would be eligible for generic. I have a donut hole on my Medicare Part D and this can make a difference... Asked by Socorro Edelen 1 year ago.

I understand we have to wait 7 years before prescription RX can have a generic on the market. I don't know exactly when Pravachol and Niaspan first went on the market. I would like to find out when they would be eligible for generic. I have a donut hole on my Medicare Part D and this can make a difference as to whether I stay with my present carrier. Answered by Werner Brei 1 year ago.

Pravachol does not yet have a generic counterpart and I cannot find out when one will be available, Niaspan however does have multiple generic brands available, go to your pharmacy and ask about Niacin Extended Release and they should be able to point one out. Hope this helps!! Answered by Honey Egner 1 year ago.


Is the PRAVACHOL ( pravastatin sodium ) lead compound or drived from a lead compound ?
well , I need also to know what is lead compound mean. if any body help me please!! Asked by Eboni Hennessee 1 year ago.

The term lead compound is used in chemistry more as research terminology, I supose pravacol is modified from its original compound so it shouldn´t be a lead compound, read below. Pravastatin (marketed as Pravachol or Selektine) is a member of the drug class of statins, used for lowering cholesterol and preventing cardiovascular disease. Initially known as CS-514, it was originally identified in a bacterium called Nocardia autotrophica by researchers of the Sankyo Pharma Inc..It is presently being marketed outside Japan by the pharmaceutical company Bristol-Myers Squibb. A lead compound (i.e. the "leading" compound, not lead metal) in drug discovery is a chemical compound that has pharmacological or biological activity and whose chemical structure is used as a starting point for chemical modifications in order to improve potency, selectivity, or pharmacokinetic parameters. Answered by Josh Thyng 1 year ago.


Pravachol is produced by ?
Asked by Alonso Ricciardone 1 year ago.

Pravachol is produced Bristol-Myers Squibb Answered by Murray Pilarski 1 year ago.

It's made from red rice yeast extract Answered by Emerita Lavezzo 1 year ago.


Can pravachol and lipitor be taken together?
My husbands dr. has put him on pravachol and now wants him to take lipitor with it. She has not tried to put him on a diet of any kind. He also has an enlarged heart. Asked by Spencer Counihan 1 year ago.

These meds are ok and will work fine together. Though he needs not to drink grapefruit juice with the liptor. It will elevate the level of the drug. With both of these drugs don't take the herbs eucalyoptus, jin bu huan, kava or red yeast rice. They will increase risk of hepatotoxicity and adverse reactions. Answered by Maddie Kresse 1 year ago.

Both poison the same system by the same means. I can not believe any doctor would prescribe both. I consider both to be deadly poison. They damage muscle tissue and are known to damage the heart leading to congestive heart failure that leads to an enlarged heart. Pharmacist for 30 years who's life was almost ruined by Lipitor. Answered by Armanda Diab 1 year ago.

You know, the saddest part of what "healthcare" has become, is that doctors are no longer interested in healing anybody. Only in how much money they can make. They have become pawns of drug manufacturers, merely legal drug-pushers that kill thousands of people every year. There is not one single drug on the market that cures anything. Drugs merely address symptoms.Every prescription and non-prescription drug made causes illnesses and diseases. Most times, the side effects of a drug are much worse than what the drug is being taken for, i.e., you will no longer have a stuffy nose, but you may have stomach cramps, and difficulty swallowing, etc. I think I will just suffer the stuffy nose, thank you. That is how the body builds up defenses to illnesses and allergies. By suffering through things like that. The body will heal itself. It needs no help, just no hindrances. God designed it that way. When a prescription drug kills thousands of people, the makers of that drug already knew that it would kill thousands. They approve it anyway. Too much money involved. There is a natural cure for almost everything, unless it has been allowed to go too far. Seek out healthcare practitioners that do not use drugs and surgery. Your health will thank you for it. Answered by Keely Dalleva 1 year ago.

I agree with midnight crier to a certain extent. Some people do require medication for some diseases. He is right about doctors not curing people. Your husband should see a naturopath or holistic practitioner for a natural health program which may be more beneficial. If he is overweight he should be on a health and exercise program designed for him to improve his health. Answered by Odis Mcgraw 1 year ago.

No. They are virtually identical. He should ask about a "heart healthy diet". Contrary to the claims of some, statins are NOT dangerous for most patients. Any medicine can cause side effects, statins are no different. Answered by Corazon Keplinger 1 year ago.

If the Dr prescribed them to take together then I would believe it to be ok.....if not sure....ask the pharamacist Answered by Melissia Ullum 1 year ago.


Statins (Lipitor, Zocor, Mevacor, Pravachol, Crestor) are the number one selling drug in our country....?
Statins (Lipitor, Zocor, Mevacor, Pravachol, Crestor) are the number one selling drug in our country. Currently, 11 million people are taking a statin drug. The current national lipid guidelines estimate that 36 million people should actually be taking statins. How do statins reduce the risk of cardiovascular... Asked by Bernarda Sharko 1 year ago.

Statins (Lipitor, Zocor, Mevacor, Pravachol, Crestor) are the number one selling drug in our country. Currently, 11 million people are taking a statin drug. The current national lipid guidelines estimate that 36 million people should actually be taking statins. How do statins reduce the risk of cardiovascular disease? stimulate production of HDL, which functions to remove excess cholesterol from cells stimulate production of LDL-cholesterol, reducing levels of free cholesterol in our blood stimulate the oxidation of LDL causes the exocytosis of cholesterol from cells; and stimulates cholesterol secretion into the intestine inhibit cholesterol synthesis; lowered cholesterol levels in cells induces the production of more LDL receptors Answered by Kristi Tamer 1 year ago.

Which would be the most beneficial? Think about this - don't just throw out an answer. What do statins do? I'll give you a hint - they have something to do with inhibiting enzymes in a biosynthetic pathway Answered by Rodrick Colomba 1 year ago.

NO problem with Lipitor. Always check out the drug online for side effects. You utimately end up being responsible for yourself and only you know yourself. I did have a bad experience with a high blood pressure med. They thought I was having heart problems and order a very expensive cath. My arteries or veins were ok, all they needed to do was change that med. Always know the side effects and watch like crazy and do those tests every three months to check his liver. Good luck. And when they do blood work, I always ask for a copy. I put the results in a spread sheet and add each new set of tests. Sometimes you may be normal but there may be a general trend you want to see and it could take place over some time and you want to be aware of it and point it out to your doctor. And if they don't pay attention, get another one. Answered by Scottie Dannhaus 1 year ago.


Why does pravachol have to be taken at bedtime?
i am awful about taking my pm meds...could i take the pravachol with morning meds ? Asked by Chanell Harnist 1 year ago.

This is in a class of drugs known as statins and used for lowering cholesterol. From the research I've done this is a once daily dose. According to the manufacturer's read out pamphlet this doesn't specify a time. The reasoning for this would be because of interactions with other drugs you take too. Please refer this question to the doctor that prescribed it. You can also call your pharmacist tomorrow too. Allot of times they can also give you the answer because of the fact they fill all of your drugs and would know the answer to this too. Don't start taking this at any other time until you've gotten further advise regarding this. Good luck and God Bless Answered by Danae Swainston 1 year ago.


What are the side effects of PRAVACHOL ?
I need the answer Asked by Keren Flenory 1 year ago.

1)Patients with underlying liver disease may have increased serum transminase levels after consumptions and may have malaise , anorexia , precipitous decreases in LDL ( low density lipoprotein ) 2) Minor increases in creatine kinase activity in plasma are observed in some patients . Rarely patients may have marked elevations . If the drug is not discontinued , rhabdomyolysis may cause myoglobinuria leading to renal injury 3)Gastrointestinal side effects have been among the most common symptoms reported by patients on pravastatin. These symptoms tended to be mild and transient in nature and resolved with continued therapy. 4) Hematologic side effects including hemolytic anemia, thrombocytopenia, thrombotic thrombocytopenic purpura (TTP), and leukopenia have occurred with some HMG-CoA reductase inhibitors. These effects may be manifestations of a hypersensitivity reaction. 5)Nervous system side effects of pravastatin have included headache (0.6% to 6.2%), dizziness, drowsiness, and weakness. Cranial nerve dysfunction, tremor, vertigo, fatigue, weight loss, memory loss, decline in cognitive function, paresthesias, peripheral neuropathy, and peripheral nerve palsy have been reported with HMG-CoA reductase inhibitors. 6)Dermatologic side effects of pravastatin have included rash (0.9% to 4.0%) and a case report of bullous erythematous lesions. Erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, photosensitivity, purpura, and alopecia have occurred with HMG-CoA reductase inhibitors. Answered by Daine Breaud 1 year ago.


If Pravachol or Lipitor aren't working....?
He has been on these for YEARS!!! I wasn't worried too much about the 214 as much as the 445 and 11 numbers-they seem very lopsided. Thanks for your answer. Asked by Herlinda Guidos 1 year ago.

will natural remedies have any effect of cholesterol? My Husband has been on both and his readings are sky high. 445 HDL and 11 LDL-- total 214. He works out, eats pretty well, no fast food, not over weight and am trying to figure out what to get naturally for him until we see the doctor again. I did buy flaxseed oil and garlic to start and am going to get the other things I have seen that are supposed to lower the numbers but if the prescriptions don't work is ANYTHING going to work? Answered by Audrie Werderman 1 year ago.

Pravachol (pravastatin sodium) and Lipitor (atorvastatin calcium) are very effective medications, but remember they're just pills, don't wait a miracle. He has to use them regularly for a couple of months. They will decrease and regulate the blood lipid levels. If they don't, talk to your doctor there are some similar mediacations like them, he/she may change them. 214mg/dl cholesterol is not a very high level, in fact according to some laboratories normal values are 120-240mg/dl. Just wait and don't panic. Those pills will help. Of course a healthy diet is important, but don't use some plants instead of medications, just keep your doctor's advices; and don't bore him too much. Answered by Lakeesha Snode 1 year ago.


When can I get pravachol and niaspan generic?
I understand we have to wait 7 years before prescription RX can have a generic on the market.I don't know exactly when Pravachol and Niaspan first went on the market. I would like to find out when they would be eligible for generic. I have a donut hole on my Medicare Part D and this can make a difference... Asked by Drucilla Morock 1 year ago.

I understand we have to wait 7 years before prescription RX can have a generic on the market. I don't know exactly when Pravachol and Niaspan first went on the market. I would like to find out when they would be eligible for generic. I have a donut hole on my Medicare Part D and this can make a difference as to whether I stay with my present carrier. Answered by Annita Fabbozzi 1 year ago.

Pravachol does not yet have a generic counterpart and I cannot find out when one will be available, Niaspan however does have multiple generic brands available, go to your pharmacy and ask about Niacin Extended Release and they should be able to point one out. Hope this helps!! Answered by Leanora Icenhour 1 year ago.


Is the PRAVACHOL ( pravastatin sodium ) lead compound or drived from a lead compound ?
well , I need also to know what is lead compound mean. if any body help me please!! Asked by Elvera Daking 1 year ago.

The term lead compound is used in chemistry more as research terminology, I supose pravacol is modified from its original compound so it shouldn´t be a lead compound, read below. Pravastatin (marketed as Pravachol or Selektine) is a member of the drug class of statins, used for lowering cholesterol and preventing cardiovascular disease. Initially known as CS-514, it was originally identified in a bacterium called Nocardia autotrophica by researchers of the Sankyo Pharma Inc..It is presently being marketed outside Japan by the pharmaceutical company Bristol-Myers Squibb. A lead compound (i.e. the "leading" compound, not lead metal) in drug discovery is a chemical compound that has pharmacological or biological activity and whose chemical structure is used as a starting point for chemical modifications in order to improve potency, selectivity, or pharmacokinetic parameters. Answered by Laureen Buzzi 1 year ago.


Pravachol is produced by ?
Asked by Kristan Armintrout 1 year ago.

Pravachol is produced Bristol-Myers Squibb Answered by Valentina Ramsey 1 year ago.

It's made from red rice yeast extract Answered by Robt Breaud 1 year ago.


Can pravachol and lipitor be taken together?
My husbands dr. has put him on pravachol and now wants him to take lipitor with it. She has not tried to put him on a diet of any kind. He also has an enlarged heart. Asked by Daryl Klopfenstein 1 year ago.

These meds are ok and will work fine together. Though he needs not to drink grapefruit juice with the liptor. It will elevate the level of the drug. With both of these drugs don't take the herbs eucalyoptus, jin bu huan, kava or red yeast rice. They will increase risk of hepatotoxicity and adverse reactions. Answered by Janene Abugn 1 year ago.

Both poison the same system by the same means. I can not believe any doctor would prescribe both. I consider both to be deadly poison. They damage muscle tissue and are known to damage the heart leading to congestive heart failure that leads to an enlarged heart. Pharmacist for 30 years who's life was almost ruined by Lipitor. Answered by Kristen Salam 1 year ago.

You know, the saddest part of what "healthcare" has become, is that doctors are no longer interested in healing anybody. Only in how much money they can make. They have become pawns of drug manufacturers, merely legal drug-pushers that kill thousands of people every year. There is not one single drug on the market that cures anything. Drugs merely address symptoms.Every prescription and non-prescription drug made causes illnesses and diseases. Most times, the side effects of a drug are much worse than what the drug is being taken for, i.e., you will no longer have a stuffy nose, but you may have stomach cramps, and difficulty swallowing, etc. I think I will just suffer the stuffy nose, thank you. That is how the body builds up defenses to illnesses and allergies. By suffering through things like that. The body will heal itself. It needs no help, just no hindrances. God designed it that way. When a prescription drug kills thousands of people, the makers of that drug already knew that it would kill thousands. They approve it anyway. Too much money involved. There is a natural cure for almost everything, unless it has been allowed to go too far. Seek out healthcare practitioners that do not use drugs and surgery. Your health will thank you for it. Answered by Jenae Silberhorn 1 year ago.

I agree with midnight crier to a certain extent. Some people do require medication for some diseases. He is right about doctors not curing people. Your husband should see a naturopath or holistic practitioner for a natural health program which may be more beneficial. If he is overweight he should be on a health and exercise program designed for him to improve his health. Answered by Deidra Hawke 1 year ago.

No. They are virtually identical. He should ask about a "heart healthy diet". Contrary to the claims of some, statins are NOT dangerous for most patients. Any medicine can cause side effects, statins are no different. Answered by Hortencia Neid 1 year ago.

If the Dr prescribed them to take together then I would believe it to be ok.....if not sure....ask the pharamacist Answered by Maryetta Cosselman 1 year ago.


Statins (Lipitor, Zocor, Mevacor, Pravachol, Crestor) are the number one selling drug in our country....?
Statins (Lipitor, Zocor, Mevacor, Pravachol, Crestor) are the number one selling drug in our country. Currently, 11 million people are taking a statin drug. The current national lipid guidelines estimate that 36 million people should actually be taking statins. How do statins reduce the risk of cardiovascular... Asked by Meta Cavaliero 1 year ago.

Statins (Lipitor, Zocor, Mevacor, Pravachol, Crestor) are the number one selling drug in our country. Currently, 11 million people are taking a statin drug. The current national lipid guidelines estimate that 36 million people should actually be taking statins. How do statins reduce the risk of cardiovascular disease? stimulate production of HDL, which functions to remove excess cholesterol from cells stimulate production of LDL-cholesterol, reducing levels of free cholesterol in our blood stimulate the oxidation of LDL causes the exocytosis of cholesterol from cells; and stimulates cholesterol secretion into the intestine inhibit cholesterol synthesis; lowered cholesterol levels in cells induces the production of more LDL receptors Answered by Ona Hulbert 1 year ago.

Which would be the most beneficial? Think about this - don't just throw out an answer. What do statins do? I'll give you a hint - they have something to do with inhibiting enzymes in a biosynthetic pathway Answered by Beverly Deever 1 year ago.

NO problem with Lipitor. Always check out the drug online for side effects. You utimately end up being responsible for yourself and only you know yourself. I did have a bad experience with a high blood pressure med. They thought I was having heart problems and order a very expensive cath. My arteries or veins were ok, all they needed to do was change that med. Always know the side effects and watch like crazy and do those tests every three months to check his liver. Good luck. And when they do blood work, I always ask for a copy. I put the results in a spread sheet and add each new set of tests. Sometimes you may be normal but there may be a general trend you want to see and it could take place over some time and you want to be aware of it and point it out to your doctor. And if they don't pay attention, get another one. Answered by Ross Rand 1 year ago.


Why does pravachol have to be taken at bedtime?
i am awful about taking my pm meds...could i take the pravachol with morning meds ? Asked by Jewel Brando 1 year ago.

This is in a class of drugs known as statins and used for lowering cholesterol. From the research I've done this is a once daily dose. According to the manufacturer's read out pamphlet this doesn't specify a time. The reasoning for this would be because of interactions with other drugs you take too. Please refer this question to the doctor that prescribed it. You can also call your pharmacist tomorrow too. Allot of times they can also give you the answer because of the fact they fill all of your drugs and would know the answer to this too. Don't start taking this at any other time until you've gotten further advise regarding this. Good luck and God Bless Answered by Kyung Paddison 1 year ago.


What are the side effects of PRAVACHOL ?
I need the answer Asked by Dorian Prejean 1 year ago.

1)Patients with underlying liver disease may have increased serum transminase levels after consumptions and may have malaise , anorexia , precipitous decreases in LDL ( low density lipoprotein ) 2) Minor increases in creatine kinase activity in plasma are observed in some patients . Rarely patients may have marked elevations . If the drug is not discontinued , rhabdomyolysis may cause myoglobinuria leading to renal injury 3)Gastrointestinal side effects have been among the most common symptoms reported by patients on pravastatin. These symptoms tended to be mild and transient in nature and resolved with continued therapy. 4) Hematologic side effects including hemolytic anemia, thrombocytopenia, thrombotic thrombocytopenic purpura (TTP), and leukopenia have occurred with some HMG-CoA reductase inhibitors. These effects may be manifestations of a hypersensitivity reaction. 5)Nervous system side effects of pravastatin have included headache (0.6% to 6.2%), dizziness, drowsiness, and weakness. Cranial nerve dysfunction, tremor, vertigo, fatigue, weight loss, memory loss, decline in cognitive function, paresthesias, peripheral neuropathy, and peripheral nerve palsy have been reported with HMG-CoA reductase inhibitors. 6)Dermatologic side effects of pravastatin have included rash (0.9% to 4.0%) and a case report of bullous erythematous lesions. Erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, photosensitivity, purpura, and alopecia have occurred with HMG-CoA reductase inhibitors. Answered by Mariko Gess 1 year ago.


If Pravachol or Lipitor aren't working....?
He has been on these for YEARS!!! I wasn't worried too much about the 214 as much as the 445 and 11 numbers-they seem very lopsided. Thanks for your answer. Asked by Jacob Garitty 1 year ago.

will natural remedies have any effect of cholesterol? My Husband has been on both and his readings are sky high. 445 HDL and 11 LDL-- total 214. He works out, eats pretty well, no fast food, not over weight and am trying to figure out what to get naturally for him until we see the doctor again. I did buy flaxseed oil and garlic to start and am going to get the other things I have seen that are supposed to lower the numbers but if the prescriptions don't work is ANYTHING going to work? Answered by Karren Haliburton 1 year ago.

Pravachol (pravastatin sodium) and Lipitor (atorvastatin calcium) are very effective medications, but remember they're just pills, don't wait a miracle. He has to use them regularly for a couple of months. They will decrease and regulate the blood lipid levels. If they don't, talk to your doctor there are some similar mediacations like them, he/she may change them. 214mg/dl cholesterol is not a very high level, in fact according to some laboratories normal values are 120-240mg/dl. Just wait and don't panic. Those pills will help. Of course a healthy diet is important, but don't use some plants instead of medications, just keep your doctor's advices; and don't bore him too much. Answered by Shaunta Mcdavis 1 year ago.


When can I get pravachol and niaspan generic?
I understand we have to wait 7 years before prescription RX can have a generic on the market.I don't know exactly when Pravachol and Niaspan first went on the market. I would like to find out when they would be eligible for generic. I have a donut hole on my Medicare Part D and this can make a difference... Asked by Chelsey Lauser 1 year ago.

I understand we have to wait 7 years before prescription RX can have a generic on the market. I don't know exactly when Pravachol and Niaspan first went on the market. I would like to find out when they would be eligible for generic. I have a donut hole on my Medicare Part D and this can make a difference as to whether I stay with my present carrier. Answered by Trent Ignacio 1 year ago.

Pravachol does not yet have a generic counterpart and I cannot find out when one will be available, Niaspan however does have multiple generic brands available, go to your pharmacy and ask about Niacin Extended Release and they should be able to point one out. Hope this helps!! Answered by Carrie Stroy 1 year ago.


Is the PRAVACHOL ( pravastatin sodium ) lead compound or drived from a lead compound ?
well , I need also to know what is lead compound mean. if any body help me please!! Asked by Lu Dukart 1 year ago.

The term lead compound is used in chemistry more as research terminology, I supose pravacol is modified from its original compound so it shouldn´t be a lead compound, read below. Pravastatin (marketed as Pravachol or Selektine) is a member of the drug class of statins, used for lowering cholesterol and preventing cardiovascular disease. Initially known as CS-514, it was originally identified in a bacterium called Nocardia autotrophica by researchers of the Sankyo Pharma Inc..It is presently being marketed outside Japan by the pharmaceutical company Bristol-Myers Squibb. A lead compound (i.e. the "leading" compound, not lead metal) in drug discovery is a chemical compound that has pharmacological or biological activity and whose chemical structure is used as a starting point for chemical modifications in order to improve potency, selectivity, or pharmacokinetic parameters. Answered by Leilani Rosengarten 1 year ago.


Pravachol is produced by ?
Asked by Lynne Dargin 1 year ago.

Pravachol is produced Bristol-Myers Squibb Answered by Ryann Borroto 1 year ago.

It's made from red rice yeast extract Answered by Kenia Lasota 1 year ago.


Can pravachol and lipitor be taken together?
My husbands dr. has put him on pravachol and now wants him to take lipitor with it. She has not tried to put him on a diet of any kind. He also has an enlarged heart. Asked by Doris Crisman 1 year ago.

These meds are ok and will work fine together. Though he needs not to drink grapefruit juice with the liptor. It will elevate the level of the drug. With both of these drugs don't take the herbs eucalyoptus, jin bu huan, kava or red yeast rice. They will increase risk of hepatotoxicity and adverse reactions. Answered by Tifany Flitt 1 year ago.

Both poison the same system by the same means. I can not believe any doctor would prescribe both. I consider both to be deadly poison. They damage muscle tissue and are known to damage the heart leading to congestive heart failure that leads to an enlarged heart. Pharmacist for 30 years who's life was almost ruined by Lipitor. Answered by Victoria Seldon 1 year ago.

You know, the saddest part of what "healthcare" has become, is that doctors are no longer interested in healing anybody. Only in how much money they can make. They have become pawns of drug manufacturers, merely legal drug-pushers that kill thousands of people every year. There is not one single drug on the market that cures anything. Drugs merely address symptoms.Every prescription and non-prescription drug made causes illnesses and diseases. Most times, the side effects of a drug are much worse than what the drug is being taken for, i.e., you will no longer have a stuffy nose, but you may have stomach cramps, and difficulty swallowing, etc. I think I will just suffer the stuffy nose, thank you. That is how the body builds up defenses to illnesses and allergies. By suffering through things like that. The body will heal itself. It needs no help, just no hindrances. God designed it that way. When a prescription drug kills thousands of people, the makers of that drug already knew that it would kill thousands. They approve it anyway. Too much money involved. There is a natural cure for almost everything, unless it has been allowed to go too far. Seek out healthcare practitioners that do not use drugs and surgery. Your health will thank you for it. Answered by Charissa Reusswig 1 year ago.

I agree with midnight crier to a certain extent. Some people do require medication for some diseases. He is right about doctors not curing people. Your husband should see a naturopath or holistic practitioner for a natural health program which may be more beneficial. If he is overweight he should be on a health and exercise program designed for him to improve his health. Answered by Afton Swedeen 1 year ago.

No. They are virtually identical. He should ask about a "heart healthy diet". Contrary to the claims of some, statins are NOT dangerous for most patients. Any medicine can cause side effects, statins are no different. Answered by Wade Attia 1 year ago.

If the Dr prescribed them to take together then I would believe it to be ok.....if not sure....ask the pharamacist Answered by Dorthea Mecum 1 year ago.


Statins (Lipitor, Zocor, Mevacor, Pravachol, Crestor) are the number one selling drug in our country....?
Statins (Lipitor, Zocor, Mevacor, Pravachol, Crestor) are the number one selling drug in our country. Currently, 11 million people are taking a statin drug. The current national lipid guidelines estimate that 36 million people should actually be taking statins. How do statins reduce the risk of cardiovascular... Asked by Kazuko Baites 1 year ago.

Statins (Lipitor, Zocor, Mevacor, Pravachol, Crestor) are the number one selling drug in our country. Currently, 11 million people are taking a statin drug. The current national lipid guidelines estimate that 36 million people should actually be taking statins. How do statins reduce the risk of cardiovascular disease? stimulate production of HDL, which functions to remove excess cholesterol from cells stimulate production of LDL-cholesterol, reducing levels of free cholesterol in our blood stimulate the oxidation of LDL causes the exocytosis of cholesterol from cells; and stimulates cholesterol secretion into the intestine inhibit cholesterol synthesis; lowered cholesterol levels in cells induces the production of more LDL receptors Answered by Majorie Affeltranger 1 year ago.

Which would be the most beneficial? Think about this - don't just throw out an answer. What do statins do? I'll give you a hint - they have something to do with inhibiting enzymes in a biosynthetic pathway Answered by Leonie Leblond 1 year ago.

NO problem with Lipitor. Always check out the drug online for side effects. You utimately end up being responsible for yourself and only you know yourself. I did have a bad experience with a high blood pressure med. They thought I was having heart problems and order a very expensive cath. My arteries or veins were ok, all they needed to do was change that med. Always know the side effects and watch like crazy and do those tests every three months to check his liver. Good luck. And when they do blood work, I always ask for a copy. I put the results in a spread sheet and add each new set of tests. Sometimes you may be normal but there may be a general trend you want to see and it could take place over some time and you want to be aware of it and point it out to your doctor. And if they don't pay attention, get another one. Answered by Santa Buffo 1 year ago.


Why does pravachol have to be taken at bedtime?
i am awful about taking my pm meds...could i take the pravachol with morning meds ? Asked by Clay Chantos 1 year ago.

This is in a class of drugs known as statins and used for lowering cholesterol. From the research I've done this is a once daily dose. According to the manufacturer's read out pamphlet this doesn't specify a time. The reasoning for this would be because of interactions with other drugs you take too. Please refer this question to the doctor that prescribed it. You can also call your pharmacist tomorrow too. Allot of times they can also give you the answer because of the fact they fill all of your drugs and would know the answer to this too. Don't start taking this at any other time until you've gotten further advise regarding this. Good luck and God Bless Answered by Hwa Acerra 1 year ago.


What are the side effects of PRAVACHOL ?
I need the answer Asked by Jolene Cachero 1 year ago.

1)Patients with underlying liver disease may have increased serum transminase levels after consumptions and may have malaise , anorexia , precipitous decreases in LDL ( low density lipoprotein ) 2) Minor increases in creatine kinase activity in plasma are observed in some patients . Rarely patients may have marked elevations . If the drug is not discontinued , rhabdomyolysis may cause myoglobinuria leading to renal injury 3)Gastrointestinal side effects have been among the most common symptoms reported by patients on pravastatin. These symptoms tended to be mild and transient in nature and resolved with continued therapy. 4) Hematologic side effects including hemolytic anemia, thrombocytopenia, thrombotic thrombocytopenic purpura (TTP), and leukopenia have occurred with some HMG-CoA reductase inhibitors. These effects may be manifestations of a hypersensitivity reaction. 5)Nervous system side effects of pravastatin have included headache (0.6% to 6.2%), dizziness, drowsiness, and weakness. Cranial nerve dysfunction, tremor, vertigo, fatigue, weight loss, memory loss, decline in cognitive function, paresthesias, peripheral neuropathy, and peripheral nerve palsy have been reported with HMG-CoA reductase inhibitors. 6)Dermatologic side effects of pravastatin have included rash (0.9% to 4.0%) and a case report of bullous erythematous lesions. Erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, photosensitivity, purpura, and alopecia have occurred with HMG-CoA reductase inhibitors. Answered by Hoa Chuc 1 year ago.


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