Application Information

This drug has been submitted to the FDA under the reference 015034/003.

Names and composition

"PONSTEL" is the commercial name of a drug composed of MEFENAMIC ACID.


ApplId/ProductId Drug name Active ingredient Form Strenght

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght

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Answered questions

Why do doctors perscribe Ponstel?
Asked by Cami Pottinger 2 years ago.

Ponstel, a nonsteroidal anti-inflammatory drug, is used for the relief of moderate pain (when treatment will not last for more than 7 days) and for the treatment of menstrual pain. Period pain is caused by the release of excess Prostaglandins - this is the substance that causes muscle contractions in the uterus walls and spasms in the lining of the uterus to help shed the lining. Ponstel contains Mefenamic Acid which helps to relieve period pain in two ways by inhibiting the formation of prostaglandins by stopping production of those prostaglandins that could cause more pain. Ponstel also blocks the prostatlandins receptor sites by stopping those prostaglandins that are causing pain. Benefits of using Ponstel includes it's rapid action because it starts working in 30-60 mins and it provides relief for up to 8 hours. Hope this answers your question, however I would recommend that if you were prescribed Ponstel and have any questions or concerns, that you discuss them with your doctor/gynaecologist. Good luck :) Answered by Quintin Dayem 2 years ago.

It relievs pain in your period But ot to all women becuz not everyones period is the same Answered by Wm Mase 2 years ago.

relief of period pain,. Answered by Evelia Sassman 2 years ago.

Side effects of Ponstel?
My doctor prescribed me ponstel for menstrual cramps. He didn't mention any problems I might have taking it, but did anyone have any unpleasant side effects? Asked by Janel Bankey 2 years ago.

No..they're ache killers..n ibuprofen is regarded most secure in its organization( NSAIDS) Side results could also be gastric ache so greater take after meals and in case f any gastric signs take renitidine.. N do not fear there's not anything to fear approximately your frame..wish I helped:) Answered by Lelah Quast 2 years ago.

Comparable Prescription To Ponstel?
I need to correct myself...I haven't taken it for years straight. I started taking it several years ago, but only for the first 5 days I'm off my BCP. And, since I take my BCP for 3 months straight, I only take it 4 times a year.And, actually, I just went to my pharmacist today and they can get the... Asked by Treena Triplette 2 years ago.

I have been taking Ponstel for severe menstrual cramps (primary dysmenorrhea) for years and completely love it! However, my insurance just decided not to cover it anymore, and I can't pay full price of around $250 per bottle. I found a drug online called Buscopan, which seemed good, but it said not to take with antihistamines, but I take Allegra on a daily basis, so I had to nix that idea. Does anybody know by experience of any other comparable medications? (I'm allergic to Naproxen.) Answered by Andrea Mohney 2 years ago.

I need to correct myself...I haven't taken it for years straight. I started taking it several years ago, but only for the first 5 days I'm off my BCP. And, since I take my BCP for 3 months straight, I only take it 4 times a year. And, actually, I just went to my pharmacist today and they can get the generic, but it's $290 for a bottle of 30. That's CRAZY!!!! FOR GENERIC?!?!?!?! Answered by Nga Schwanz 2 years ago.

Ponstel (also called Mefanamic Acid) is not yet available in the generic form, at least in the United States. However, it is a pain reliever, an NSAID like ibupofen, naproxen, ketorolac, and several others. Even if you can't take naproxen, you and your doctor may be able to find an alterantive that will work for you. There are literally more than a dozen choices now, and with Ponstel costing so outrageously much (!!), it is worth trying some of the others. By the way, I don't know how many days a month you take Ponstel, but it is meant for short-term use only. I think the maximum is about 7 days. If you are taking "for years," it's time to talk with your doctor anyway. It may be a good idea to switch to something else. I hope this helps, and I wish you good luck. Answered by Loyd Fjeseth 2 years ago.

What does Ponstel do to you?
Asked by Billie Whittman 2 years ago.

Ponstel is a drug used to treat moderate menstrual pain. Side effects could include abdominal pain, nausea, diarrhea and other stomach upsets. Do not take it if you are asthmatic or suffer from hay fever or other respiratory allergies. You should also not take it if you have stomach ulcers or kidney disease. Nursing mothers and persons with heart conditions are also warned not to take this medication. There is a ton of information on various web sites about this medication. Answered by Billy Papp 2 years ago.

I took it for rather undesirable cramps bec. no longer lots else worked different than for vicodin and the dr. did no longer choose to furnish that to me for cramps bec. they ought to be very careful now approximately giving that out. besides, the ponstel i in basic terms took one time bec. it made me like great b@#$%. i became undesirable and all i needed to do became sleep. no longer something like my known self no longer even with pms. i purely gave the completed bottle back to the dr. I even have additionally tried equagesic, and butalbital. they have been ok better than pamprin or something like that. purely undergo in recommendations that a lot of human beings have diverse reactions to any medicine. Ponstel is offered and that i'm specific that it does help a lot of human beings. i became purely no longer considered one of them. The area outcomes usually seem undesirable on exceptionally lots any medicine too. the final ingredient i will inform you is to aim it and notice the way it works for you. in case you have a foul area result end taking it and ask for some thing else. Answered by Elvin Olander 2 years ago.

If I take Ponstel 250, does it intefer with Alprazolam 0.25?
Ponstel is an anti-inflamatory that treats menstrual pain. Alprazolam is a small dosage to treat anxiety. Asked by Sondra Braithwaite 2 years ago.

These are the meds listed that could cause an adverse reaction but if your family doctor did not prescribe one of them then I could call him/her and double check to make sure just to be safe. Do not take Ponstel with: a blood thinner such as warfarin (Coumadin; a diuretic (water pill) such as furosemide (Lasix); cyclosporine (Gengraf, Neoral, Sandimmune); lithium (Eskalith, Lithobid); methotrexate (Rheumatrex, Trexall); steroids (prednisone and others); or aspirin or NSAIDs (non-steroidal anti-inflammatory drugs) such as diclofenac (Voltaren), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), ibuprofen (Advil, Motrin), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), meclofenamate (Meclomen), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others. If you are using any of these drugs, you may not be able to use mefenamic acid or you may need dosage adjustments or special tests during treatment. There may be other drugs not listed that can affect Ponstel. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your family doctor. Answered by Odette Boak 2 years ago.

yet are the 6's tattooed on some element of your warm bod ? i f so,then i'd be scared,and would desire to pass come across a pointy wood stake and mallet,to maintain us all,nothin own ya understand. Answered by Arletta Nipp 2 years ago.

I take Morphine and Vallium, yes you can. Go to for any medicine questions. Answered by Elvis Beltre 2 years ago.

Ponstel for really bad cramps....?
I had my baby 4 months ago and have had really bad menstrual cramps since. My Dr wants me to try Ponstel which from what I have read can be really dangerous. I want to know if it really works before taking it. Has anyone here tried it and does it really work? Asked by Joannie Griesbaum 2 years ago.

From the little I've read about Ponstel I would not take it. Doctors seem to like to push the prescription meds on people. I get wicked menstrual cramps too, so bad that sometimes I can hardly get out of bed. In some of my research I have found that sugar can makes cramps worse, because it causes inflammation. I have also personally felt the cramps getting worse when I decided against better judgement to eat a chocolate bar. I would suggest staying away from sugar a few days before your period starts, and if your cramps are still bad, try Robax Platinum, it is a strong muscle relaxant and helps my cramps more than anything else. Hope you find something that works, that's safer than Ponstel. Answered by Candra Shinaberry 2 years ago.

I took it for really bad cramps bec. not much else worked except for vicodin and the dr. didn't want to give that to me for cramps bec. they have to be very careful now about giving that out. anyway, the ponstel i only took one time bec. it made me like super b@#$%. i was awful and all i wanted to do was sleep. nothing like my usual self not even with pms. i just gave the whole bottle back to the dr. i have also tried equagesic, and butalbital. they were ok better than pamprin or anything like that. Just remember that many people have different reactions to any medication. Ponstel is on the market and I am sure that it does help many people. I was just not one of them. The side effects generally look bad on pretty much any medication too. The best thing i can tell you is to try it and see how it works for you. if you have a bad side effect stop taking it and ask for something else. Answered by Elijah Huenergardt 2 years ago.


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