PLATINOL Ressources

Application Information

This drug has been submitted to the FDA under the reference 018057/001.

Names and composition

"PLATINOL" is the commercial name of a drug composed of CISPLATIN.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
018057/001 PLATINOL CISPLATIN INJECTABLE/INJECTION 10MG per VIAL
018057/002 PLATINOL CISPLATIN INJECTABLE/INJECTION 50MG per VIAL

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
018057/001 PLATINOL CISPLATIN INJECTABLE/INJECTION 10MG per VIAL
018057/002 PLATINOL CISPLATIN INJECTABLE/INJECTION 50MG per VIAL
018057/003 PLATINOL-AQ CISPLATIN INJECTABLE/INJECTION 0.5MG per ML
018057/004 CISPLATIN CISPLATIN INJECTABLE/INJECTION 1MG per ML
074656/001 CISPLATIN CISPLATIN INJECTABLE/INJECTION 1MG per ML
074713/001 CISPLATIN CISPLATIN INJECTABLE/INJECTION 10MG per VIAL
074713/002 CISPLATIN CISPLATIN INJECTABLE/INJECTION 50MG per VIAL
074735/001 CISPLATIN CISPLATIN INJECTABLE/INJECTION 1MG per ML
074814/001 CISPLATIN CISPLATIN INJECTABLE/INJECTION 1MG per ML
075036/001 CISPLATIN CISPLATIN INJECTABLE/INJECTION 1MG per ML
091062/001 CISPLATIN CISPLATIN INJECTABLE/INJECTION 1MG per ML
206774/001 CISPLATIN CISPLATIN INJECTABLE/INJECTION 1MG per ML
207323/001 CISPLATIN CISPLATIN INJECTABLE/INJECTION 1MG per ML

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Answered questions

What companies manufacture cisplatin or platinol?
What companies manufacture the chemotherapy drug, cisplatin? it is also known as platinol and CDDP. i can't seem to find one. i googled it and i felt like i was looking at the black market for chemo drugs. I need to know for a chemistry project. Asked by Brigida Gnegy 1 month ago.

This Site Might Help You. RE: What companies manufacture cisplatin or platinol? What companies manufacture the chemotherapy drug, cisplatin? it is also known as platinol and CDDP. i can't seem to find one. i googled it and i felt like i was looking at the black market for chemo drugs. I need to know for a chemistry project. Answered by Meryl Abes 1 month ago.

That pretty much defeats the purpose of what they're used for. And if breathing is your concern when you're wearing one, then maybe you're doing something wrong. Answered by Jodi Lungsford 1 month ago.

There are some from Bristol-Myers Squibb, TOCRIS Bioscience and more from US Answered by Rosaline Puls 1 month ago.


Cisplatin (Platinol) question?
I know that c. is not the answer since Reglan is usually given 30 minutes prior to cisplatin. Asked by Palmer Karr 1 month ago.

if I'm receiving cisplatin (Platinol) intravenous chemotherapy, which of the following prescriptions would be questioned? a. a bolus dose of furosemide b. intravenous fluids at 150 cc per hour c. Reglan 30 to 60 minutes prior to cisplatin d. a follow-up appointment for a bone marrow test in 2 weeks thank you Answered by Emelina Hady 1 month ago.

The answer is (b). You should have intravenous fluids of minimum of 100 to 150 cc per hour before and while administrating Cisplatin for Cancer Chemotheraphy. This is a must. Before and while receiving cisplatin large volumes of intravenous fluids are given to keep the kidneys flushed with water. If patients have severe kidney problems the physician will either not use cisplatin or decrease the dose being used.Cisplatin may cause the body to waste normal electrolytes that circulate in the body (potassium, magnesium, phosphate, sodium, calcium) resulting in low levels of these electrolytes. For all these reasons enough quantity offluids should be given.- Answered by Henriette Taccariello 1 month ago.


What are the long term effects from taking platinol,taxotere for treatment of lung cancer?
my father is taking platinol and taxotere for his cancer he has had raidation and kemo for the past seven months and was woundering if there is any long term effects from these drugs. and if so how long will they last. Asked by Ying Barlowe 1 month ago.

I had chemo last fall, one of which was taxotere. Some people have no side effects. I did have some damage to the nerve endings in my extremities (hands and feet), but I'll tell ya... I'd rather have those side effects than not have survived the cancer! Its all a balancing act. Which would you rather deal with... the cancer, or the side effects? I chose the side effects. There are some good sites on the web, like the Mayo Clinic, etc. Answered by Maida Stelling 1 month ago.

Well, Cisplatin can cause hearing loss and kidney damage if you take it for a long time. Taxotere can cause neuropathy which is generally mostly reversible, but can persist if you do not stop the drug after symptoms start. If you father has lung cancer, the benefits probably outweigh any long term risks. Answered by Iola Olmos 1 month ago.

hopefully life! Answered by Allan Hardy 1 month ago.


How do you find the Molecular Formula... if?
Platinol has MM= 300.07 g/mol and composed of 2.02% Hydrogen, 9.34% Nitrogen, 23.63% Chlorine and rest Platinum... then what is the molecular formula of Platinol? If anyone can give me a step by step because I just can't recall how to do this??? Thanks! Asked by Milan Bilbo 1 month ago.

assume 1 mole platinol.. by definition that has mass = 300.07 grams. if we calculate the number of moles of each species / mole of patinol, we will have the molecular formula... H = .0202 x (300.07 g) = 6.06 g H = 6.06 / 1.01 = 6 moles H N = .0934 x 300.07g = 28.02 g = 28.02 / 14.01 = 2 moles N Cl = 0.2362 x 300.07g = 70.91 g Cl = 70.9 / 35.45 = 2 moles Cl Pt = 300 - (6.06 + 28.02 + 70.91) = 195.0 g Pt = 195 / 195 = 1 mole Pt so molecular formula is PtN2H6Cl Answered by Glenna Langille 1 month ago.

Out of 100%, you have 2.02% hydrogen, 9.34 % nitrogen, and 23.63% chlorine. Adding, they total 34.99%. Subtract this from 100% and the rest is platinum = 65.01%. To make it easier, round. = 2% hydrogen + 9 % nitrogen + 24% chlorine + 65 % platinum = 100%. Use the percentages to find out how many grams you have of each substance: 2% = .02 x 300.07 = 6 grams hydrogen 9% = .09 x 300.07 = 27 grams nitrogen 24% = .24 x 300.07 = 72 grams chlorine 65% = .65 x 300.07 = 195 grams platinum Added together they total 300 grams platinol Now find the lowest common denominator. Since 27 was an odd number and smaller than the other odd number (195), I started multiplying it by 1 then by 2 then by 3 etc. until I came to 4. 4 x 27 = 108. Each of the other numbers could be divided into it. 108 / 6 = 18, 108/27 = 4, 108/72 = 1.5 and 108/195 = .5 So to make everything whole numbers I doubled the numbers which made 36 H's, 8 N's, 3 Cl's and 1 Pt's. So the formula would be: H36 N8 Cl3 Pt Answered by Rana Freel 1 month ago.

im not gonna do the maths for you but ill guide you through. First, 2.02% is hydrogen 9.34% is nitrogen 23.63% chlorine ? % platinum (100% minus the others) then, divide with their relative molecular mass accordingly starting with say, hydrogen, 2.02 divide 1 , 9.34 divide 14 . then round up the numbers to an integer and thats the empirical formula. to get the molecular formula, try trial and error method, you can even use some algebra. (the empirical formula)n replace n with any interger, lets begin with 1, and multiply accordingly with the relative molecular mass and see whether it matches 300.07 Answered by Tena Hosterman 1 month ago.

Divide mass percentages by atomic masses. Remember to include Platinum in your calculation - whatever isn't something else, is platinum. That gives you the ratio of different kinds of atoms, so divide through by the smallest. If you're left with a fraction, multiply through to get rid of it. Answered by Jennifer Pistole 1 month ago.


Help with chemistry?
Platinol is an anticancer drug with molecular formula Pt(NH3)2Cl2. Platinum is a precious metal, and the cost of making platinol is determined by the cost of the platinum, which is $19.00 per gram. One dose of the drug contains 11.9 mg of platinol. How many doses of platinol could be produced for 71.8 dollars? Asked by Brendon Slessman 1 month ago.

this is a simple math question. it's dimensional analysis. You take your given, $71.80. find out how many grams you can buy. That's just $71.80 * 1gram/$19.00. Now that you have grams you have to divide it by the dosage amount (in grams) to see how many doses you can make. Answered by Carry Shirk 1 month ago.

First: find how many mg of platinum can be purchased for $ 71.80. Call that "A" mg Next: Find the amount of platinum in 11.9 mg of platinol. This will require knowing the atomic weight of platinum and the mol wt of platinol. The relation is (amt Pt)= 11.9*at wt Pt/mol wt platinol= Call that "B" mg. Finally, divide A by B to get answer. Rough estimate, about 300-400. Answered by Jessika Joerger 1 month ago.


What are the most common chemicals used in chemotherapy?
I know there are hundreds, and that most of them fit into four categories: alkylating agents, vinca alkaloids, cytotoxic antibiotics and anti-metabolites but in those four categories which one is the MOST used/administered? Asked by Dave Davide 1 month ago.

ALKYLATING AGENTS are drugs that work by directly attacking the DNA of a cell. These drugs can work at any time of the cell cycle, but are most effective during DNA synthesis. They are used to treat Hodgkin's disease, lymphomas, chronic leukemias, and certain carcinomas of the lung, breast, prostrate, and ovary. Alkylating agents are administered either orally or intravenously. Examples of drugs in this category are Cyclophosphamide and Mechlorethamine, Cisplatin (Platinol). Read a very detailed history of platinum based drugs (Cisplatin) and their method of action and use. NITROSOUREAS are similar to alkylating agents, and work by inhibiting the changes necessary for DNA repair. A very important feature of this class of drugs is that they can cross the blood-brain barrier which makes them very useful for treating brain tumors. They can also be used to treat lymphomas and melanomas. Nitrosoureas are administered either orally or intravenously. Examples of drugs in this category are Carmustine and Lomustine. ANTIMETABOLITES block cell growth by interfering with DNA synthesis. These drugs work by mimicking a substance involved in DNA synthesis, inhibiting production of an acid necessary for DNA to be synthesized. These drugs affect the "S" phase of the cell cycle. Antimetabolites are used to treat tumors of the gastrointestinal tract, breast, and ovary. They are administered either orally or intravenously. Examples of these drugs are 6-mercaptopurine and 5-fluorouracil. ANTITUMOR ANTIBIOTICS work by binding with DNA to prevent RNA synthesis. These also prevent cell growth by preventing DNA replication. Antitumor antibiotics prevent the DNA from reattaching itself together which causes the cell to die. This category of drugs is used to treat a wide variety of cancers including testicular cancer and leukemia. Antitumor antibiotic drugs are administered intravenously. Some examples of this category are Doxorubicin and Mitomycin-C. PLANT(VINCA) ALKALOIDS work by preventing cell division. During metaphase, mitotic spindles hold the two sets of DNA the cell needs to divide. The spindles are formed using a protein called tubulin. Plant alkaloids bind to tubulin, which prevents the formation of mitotic spindles. Without mitotic spindles, the cell cannot divide. These drugs are derived from plants and are used to treat Wilm's tumor, and cancers of the lung, breast, and testes. Plant alkaloids are administered intravenously. Some examples of this category are Vincristine and Vinblastine. STEROID HORMONES. These drugs modify the growth of hormone dependant cancers. They induce a change in the three dimensional shape of the receptor on a cell preventing the cell's binding to the needed estrogen response element on the DNA. These drugs are most commonly used in treating breast cancer. The hormones are administered orally. Some examples of this category are Tamoxifen and Flutamide. Answered by Shakia Sternberg 1 month ago.

This Site Might Help You. RE: What are the most common chemicals used in chemotherapy? I know there are hundreds, and that most of them fit into four categories: alkylating agents, vinca alkaloids, cytotoxic antibiotics and anti-metabolites but in those four categories which one is the MOST used/administered? Answered by Kyla Spoth 1 month ago.


Life expectancy after chemo?
full retroperonitonal lymph node dissection, stage 3 a, 5 rounds of vp16(platinol)bliomycin and etopocide ca fee for over 20 years, now haveing immunine system breaking down with heart and pulmonary insifficancy-what can i do? Asked by Gabriele Aber 1 month ago.

Sounds like you need to know God in your life as a Christian, and then you can pray about your life. God is your spiritual Father, life, love, all-powerful, all-knowing, eternal, holy. This is how to know God -- the basic Christian message and prayer --- you need to accept God's Son, Jesus Christ, into your life to be a born again Christian and follow God's ways so you can receive God's guidance in your life and get to heaven after you die. Knowing God can transform your life. When you know God, then pray about your life, God can help you live a better life. As God is love, life is primarily about love and relationships in order to have a rich and full life. Also, you need to know God's Son, Jesus Christ, in your life as your Lord and Savior as Jesus died on the cross as payment for our sins. Having Him with you will give you God's blessing and forgiveness, as you live God's way. Not following God leads to hell, eternal suffering. Instead, there is an important prayer to pray to become a born again Christian. This prayer should be said with faith in God and a sincere heart: "Dear God, I know that I am a sinful person and I don't want to be like this anymore. I know that Jesus Christ died on the cross as payment for our sins, and I want to accept Jesus Christ into my life as my Lord and Savior so I can receive God's forgiveness, guidance, and go to heaven someday. Thank you, dear God, for your mercy and guidance; in Jesus' name. Amen." This prayer can take you to a new place in your relationship with God and transform your life. After saying this prayer, you should check out a Christian church, like Baptist or Lutheran. The church can get you baptized and prayed for, and you can pray for yourself daily. Also, get into their Bible study group so you can learn more about God, Jesus, and God's will for your life. The Bible is God's instruction book about how to live a God-honoring life so you can go to heaven after you die. Ways to stay connected to God's path include loving God and Jesus Christ, obeying God's ways, daily Bible reading, daily prayer for yourself and others, getting to church, having your church prayer group and/or pastor pray for you, fasting with prayer for a higher level of prayer, getting with other Christians and doing a Bible study, singing hymns to God, taking communion with the church, helping and loving others, expressing your gratitude to God for His help in your life by telling others of your progress and helping them draw closer to God too, tithing, volunteering at church. Answered by Jim Winberg 1 month ago.

nobody know how long we live please don't give up hope , my mom has a stage 4 breast cancer more than 5 body parts is affected but she's doing well , tell to your mom just forget about your cancer because mental treatment is also important than physical life expectancy after chemo - no buddy know that sometime 5 years to 20 years or more :-) Answered by Irena Szumigala 1 month ago.

You have no date stamped on you, you can live 100 years or 100 days. Answered by Milissa Garriott 1 month ago.


HARD CHEMISTRY QUESTION?
The current world market price of platinum metal is about $1180 per Troy ounce ( 1 Troy ounce = 31.10g). How many grams of Platinol can be made for1.00 million dollars, assuming the cost of Pt determines the cost of the drug? Asked by Cierra Lide 1 month ago.

This is actually a mathematically question: $1 million / ($1180/31,10grams) = 26.356 kg. Explanation: First you calculate how much 1 gram cost (1180/32,3) Then you divide 1 million to the cost per gram. Answered by Shonna Cantore 1 month ago.

This is not a Fair question you need to tell us more information to answer first how much platinum is in platinol and what is the cost of the other ingredents in platinol the math part of this equation is not difficult at all but there are far too many unknowns to answer it correctly as it stands now. Answered by Shantell Mceathron 1 month ago.

1000000/1180 gives amount of troy ounces for $1m.(847.5) 847.5*31.10g=26357g or 26.357kg Answered by Mica Percifield 1 month ago.


How long after you finished chemo for breast cancer till your periods are regular?
Last Febuary (2006) I finished chemo for breast cancer I took the following chemos:Brand GenericEllence epirubicinCytoxan cyclophosphamideAdrucil 5-Fu, fluorouracilTaxotere docetaxelXeloda capecitabinePlatinol cisplatinVepecid,VP16 etoposideAvastin bevacizumabHow long might it take for my... Asked by Dani Schmautz 1 month ago.

Last Febuary (2006) I finished chemo for breast cancer I took the following chemos: Brand Generic Ellence epirubicin Cytoxan cyclophosphamide Adrucil 5-Fu, fluorouracil Taxotere docetaxel Xeloda capecitabine Platinol cisplatin Vepecid,VP16 etoposide Avastin bevacizumab How long might it take for my cycles to become regular? Answered by Amelia Barclay 1 month ago.

As stated, everyone is different... I had bc 2x and the first time I had Cytoxin Oh geesh, I forget the name now..Its also known as the RED DEVIL and something else mixed in there.. It was 9 mos The 2nd time I had Xeloda and something else (sorry...) can't remember and it was like 8 mos. GB hope you are doing okay..I am so far :) Answered by Valentine Elsinger 1 month ago.

I'm not sure the only reason I'm replying is that i had breast cancer and only had radiotherapy, i was then put on tamoxifen and my periods have stopped altogether, i think the best thing to do is ask your surgeon or oncologist next time you have an appointment Answered by Gregory Postma 1 month ago.

EVERYONE IS AN INDIVIDUAL BUT I SPEAK FOR MYSELF.....MY PERIOD NEVER CAME BACK AND IT'S BEEN THREE YEARS SINCE THE ND OF CHEMO. Answered by Barbar Bretos 1 month ago.


How did lance armstrong beat his cancer?
And what chemo did he get Asked by Marlene Prothro 1 month ago.

The standard chemotherapeutic regimen for the treatment of this type of cancer is a cocktail of the drugs BEP (bleomycin, etoposide, and cisplatin (or Platinol)). Armstrong, however, chose an alternative, VIP (etoposide, ifosfamide, and cisplatin), to avoid the lung toxicity associated with the drug bleomycin.[7] This decision may have saved his cycling career. His primary treatment was received at the Indiana University (IU), Indianapolis, Medical Center, where Dr. Lawrence Einhorn had pioneered the use of cisplatinum to treat testicular cancer. His primary oncologist there was Dr. Craig Nichols.[7] Also at IU, his brain tumors were surgically removed and found to contain extensive necrosis (dead tissue). His last chemotherapy treatment was received on December 13, 1996 He did not change his diet or lifestyle nor any alternative tratments. Answered by Alton Butzlaff 1 month ago.

Lance Armstrong Cancer Answered by Torie Zeals 1 month ago.

Testicular cancer is a form of cancer that responds very well to chemo, even after it has spread. His cancer had actually spread to many parts of his body, and with most other cancers he would have had almost no shot. Answered by Maryalice Smolnicky 1 month ago.

Here is what hopefully he didn't do. Check out the side effects on this website. Answered by Ross Leep 1 month ago.

read his book. he appears to be genetically gifted. Answered by Romona Peakes 1 month ago.


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