Application Information

This drug has been submitted to the FDA under the reference 013056/001.

Names and composition

"PENTHRANE" is the commercial name of a drug composed of METHOXYFLURANE.


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Answered questions

Which of these depressants acts as both an analgesic and a sedative?
inhalants tranquilizers steroids narcotics thanks Asked by Tiny Akley 2 years ago.

Today about the only group that fit the bill are narcotics. Decades ago there was an inhalant called Penthrane that could be used as an analgesic in low concentrations and a general anesthetic in high concentrations. Answered by Haywood Fetrow 2 years ago.

Can you take doxycycline and acyclovir together?
I have 2 medicines and wonder if they can be taken together. One of them is Doxycycline and the other is Acyclovir? Asked by Chae Taccariello 2 years ago.

Doxycycline and acyclovir are absolutely safe together. Here is a compiled list of anything that contraindicates doxycycline. Anticoagulant Drugs: Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. Penicillin: Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracyclines in conjunction with penicillin. Antacids and Iron Preparations: Absorption of tetracyclines is impaired by antacids containing aluminum, calcium, or magnesium, bismuth subsalicylate, and iron-containing preparations. Oral Contraceptives: Concurrent use of tetracycline may render oral contraceptives less effective. Barbiturates and anti-epileptics Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. Penthrane: The concurrent use of tetracycline and Penthrane®(methoxyflurane) has been reported to result in fatal renal toxicity. *From Different Source* Cholesterol-lowering medications such as cholestyramine (Prevalite, Questran) or colestipol (Colestid). Isotretinoin (Accutane). Tretinoin (Renova, Retin-A, Vesanoid). An antacid such as Tums, Rolaids, Milk of Magnesia, Maalox, and others. A product that contains bismuth subsalicylate such as Pepto-Bismol. Minerals such as iron, zinc, calcium, magnesium, and over-the-counter vitamin and mineral supplements. A blood thinner such as warfarin (Coumadin). A penicillin antibiotic such as amoxicillin (Amoxil, Trimox, others), penicillin (BeePen-VK, Pen-Vee K, Veetids, others), dicloxacillin (Dynapen), oxacillin (Bactocill), and others. As noted, methoxyflurane and doxycycline can be fatal and should never be taken together. You'll be perfectly safe taking them together, as they do not interact with each other in any significant way. Answered by Jamila Drahos 2 years ago.

Drug Interactions With Acyclovir Answered by Sheilah Amidei 2 years ago.

They are not cancelling each other, but if they are not working you need at least dental surgery, and a look at the pelvis -- sono or CT. Back to Dr you go! Answered by Yevette Trenor 2 years ago.

What is the proper name for sleeping gas?
So is there one that could make you temporarily lose consciousness? And not die? Asked by Otilia Swancey 2 years ago.

There are lots of different harmful gases that are considered to be "sleeping gas": halothane vapour (Fluothane) methyl propyl ether (Neothyl) methoxyflurane (Penthrane) fentanyl Answered by Brianna Knipping 2 years ago.

First off, there is not a gas that actually makes you fall asleep. There are gases that make you lose consciousness some of which that you never regain back.. Carbon Monoxide.. unconsciousness before death. Bomine, Chlorine, Sulfur Dioxide, Hydrogen Sulfide, and the Nerve Gases and "Mustard Gas" all poisonous gases that kill you. Gases that cause unconsciousness but aren't necessarily dangerous (person can be revived easily after) are gases like Nitrous Oxide ( N2O ). There are other gases that can make you unconscious as well but I believe the main one you are looking at is Nitrous Oxide. And no there is not a gas that makes you fall asleep. Answered by Tonette Darou 2 years ago.

Gas price board ? Or today's gas price on the billboard . Not sure though Answered by Damion Mince 2 years ago.

Nitrous oxide is one of several that do this. Answered by Sheba Furlan 2 years ago.

chloroform (liq) CHCl3 10mL will put people to sleep after smelling it for 10-15s if the quantity is small (<10mL), the person will be knocked down for 1-2 hr unconscious then wake up Answered by Vernie Peard 2 years ago.

list of sliping gases Answered by Tama Millerr 2 years ago.

nytrogen protoxide - N2O Answered by Jerrold Antillon 2 years ago.

Question about sleeping gas?
when they give you the gas to make you fall asleep before you go into operation how many people get paralyzed from it so they feel all the pain but cant blink etc.??thanks in advance. Asked by Juan Alesse 2 years ago.

Like in the 2007 movie "Awake" I assume? Happens to about 30,000 people annually according to a 2007 USA today article... But that's all anesthesia, not necessarily "sleeping gas" only... 2007 also had a noted research article that measured rates of post-traumatic stress disorder (but the same research paper also noted the high potential for bias in selection). That paper is listed in the sources below. Anyway, back to the point... via Wikipedia: "Anesthesia awareness, or unintended intra-operative awareness occurs during general anesthesia, on the operating table, when the patient has not been given enough of the general anesthetic or analgesic to render the patient unconscious during general anesthesia (often when agents used to paralyze the patient have been administered). However, it can also occur in the post anesthesia care unit (PACU) or in the intensive care unit (ICU), where patients are kept sedated, tranquilized and sometimes paralyzed (and intubated) and are connected to life support systems, awaiting normalization of their physiology." Personally, I had the post-surgery version following a partial foot ablation, and while I wasn't paralyzed, I did learn the following: 1. That the usual 1-10 method of rating pain is completely inadequate for when your previous scale would rate a new version as 200 2. It is indeed possible to wake up screaming. But your main point: "Awareness occurs in 20,000–40,000 patients out of the 20 million US surgeries performed each year (between 0.1% and 0.2%) Large trials have demonstrated that around 1 to 2 per 1000 patients experience some form of awareness " Keep in mind some key points though: "some form of awareness" usually doesn't indicate either 1. paralysis while you're being operated on 2. the waking up screaming scenario Anyway, it's extremely unlikely in general, and with the omission of other risk factors such as also muscle relaxants it's even more rare. "Several studies have indicated this occurs in about 1 or 2 per 1000. Other studies show a much lower incidence, usually because the anesthesiologists know they are in a trial and are very experienced, not trainees as is common in Europe. Some studies suggest it is a rare phenomenon, with rates varying from 0.13% to as low as 0.0068%" Since you stated "sleeping gas", such as Fluothane, Neothyl, and Penthrane you can probably assume they would be utilizing a "knock-out" gas... that is, if it doesn't work, you're still awake (and can move) and hence about to have the chance to experience anesthesia awareness. Answered by Timika Stouffer 2 years ago.

I'm so sad because I never kissed a girl?
I'm 33. I know I was supposed to do that at 14. The sad thing was that I knew when I didn't take action it was all over for me then. I'm too shy and really fear rejection besides, many just see me as a creep. I have nothing in common with anyone. I like young girls... but obviously I'm only... Asked by Aurelio Behm 2 years ago.

I'm 33. I know I was supposed to do that at 14. The sad thing was that I knew when I didn't take action it was all over for me then. I'm too shy and really fear rejection besides, many just see me as a creep. I have nothing in common with anyone. I like young girls... but obviously I'm only interested in one thing there. I have "no game" anyways. I'm like that fumbling 8th grader who never grew up. I have a hard time even sticking around with someone for enough time to get to know them. I had a couple guy friends who abandoned me and I was really trying to hold onto them. I really think without love life is pointless. I'm not a religious type who seems to lack human feeling. Women have not been kind when I had the guts to go up to them. I guess timidity calls for abuse? Not sure why. Sadly I think I missed out on a very promising life. In truth I believe my whole life fell apart because of my lack of love life and not growing up. Can anyone relate? Answered by Setsuko Buckler 2 years ago.

I have never kissed a girl either. It hurts. I dream about it, while I'm awake, and when I'm asleep. I have tried to substitute that special kiss and intimacy with drugs. The years 20-26 for me was nothing but Shooting up Morphine into my veins, taking massive amounts of Valium, Ativan, Xanax, Klonopin, Rohypnol, Barbiturates, Oxycontin, Methadone, Buprenorphine, Fentanyl, Seroquel, Olanzapine, Risperidone, Haldol, Largactil, Stelazine, Prozac, Luvox, Aropax, Clomipramine, Zoloft, Prothiaden, Endep, Penthrane, Atropine, Cogentin, Benzhexol, Lithium, Epilim, Gabapentin, Lyrica, Buspar, Zolpidem, Zopiclone, muscle relaxants, Beta-blockers, adrenaline alpha blockers...etc etc etc You know what, my friend? NONE OF IT HELPED. I strongly advise not to take drugs unless you want to be like me and be involved in car accidents, ED overdoses, infections, rehab clinics, seizures, fraud... I don't think you want that, buddy. DO NOT TAKE DRUGS. You will get your kiss, someday. Answered by Celinda Barfuss 2 years ago.

Hey there I have a cousin who is around your age and has been single all of his life. He says that he has a hard time with it, but what you both need to realize is that just because you haven't had your share of dating yet does not make you weird or different from anyone else. That's what's great about relationships. It is personal for everyone, and no one else's business as to how far you have gotten in your dating life. You have not missed out, you just are still waiting for that one person who will completely change your life around. Do not feel bad about your situation, it is normal for many people. Just keep your confidence high and keep trying to meet more and more people, and I guarantee that there is someone out there just waiting to meet you :) Answered by Manual Durnil 2 years ago.

I can't really relate but kinda. Im seventeen girl and haven't kissed a guy. So who cares. Who needs a guy/girl in their life to feel completed anyway. The only part I can relate to is I'm shy. Answered by Suzie Brallier 2 years ago.

Can I take doxycycline with my supplements?
I'm taking doxycycline. I also take fish oil, garlic, vegetable powder, over 50 vitamin, and a DHEA supplement. Are these all safe to take together? The doctor also gave me a Flexeril for muscle spasms to take tonight. Asked by Aleta Hilovsky 2 years ago.

Antibiotics are sought after for causing sunlight sensitivity, because they are excreted through the exterior. Earthworm protein?!?!? basically because the digestive enzymes of worms smash down elements (as does your own) that does through no potential mean those a) the protein contains those enzymes and b) that those enzymes make it previous your abdomen acid. That has were given to be nastiest supplement scam I easily have each and every - EVER - heard of, i fairly desire you aren't to any extent further paying a lot to be suckered through that one... Edit 2: thanks for the pleasing emails. again, i am going to advise you communicate on your well-being practitioner about eating dehydrated worms. i ought to communicate to a psychiatrist besides. Answered by Latia Waughtel 2 years ago.

Are there options other than an epidural to control pain?
Asked by Suzette Koeck 2 years ago.

Sure, lots of them. There are the psychological approaches, involving distraction therapy such as focusing on breathing, or hypnosis, that sort of thing. There are physical therapy-like approaches, involving changing of position, walking, using a large ball, application of heat, giving birth in a bathtub, that sort of thing. There are all sorts of medicines that can be given, such as opiods (morphine like drugs), agonist-antagonist type of drugs like Nubain, and a variety of inhaled drugs such as nitrous oxide or Penthrane. Spinal anesthesia, which can either be a "saddle block" for delivery, or an "intrathecal narcotic" (fancy name for a spinal with fentanyl in it), can give good pain relief for about 90 minutes. Caudal anesthesia is a different form of epidural and isn't done much these days. Answered by Pattie Borja 2 years ago.

There are other options. You can choose to go through labor using breathing and relaxation techniques. However, if you want medical interventions, an epidural is the way to go. There are other medical options such as narcotics but these are not as effective as an epidural and causes drowsiness for both the mother and the baby. The downside to an epidural is that you will not be able to walk around after getting one and it prolongs labor. Other than that, the risks are minimal. Some women experience back pains for a few weeks after getting the epidural. I'm planning on taking labor as it comes. I'm not planning on getting an epidural but I'm not planning on refusing one either. If my breathing and relaxation techniques fail I'm all for getting an epidural. However, I think it should be used as a last resort rather than a first option. But...that's just my opinion. Every woman will cope with and go through labor in her own way and no way is wrong. Answered by Laticia Nazzal 2 years ago.

There are several IV medications to choose from. I found that they wore off quickly and made me "woozy" and not feel well in general. Using a birthing ball helped me cope with my pain greatly. Warm compresses, warm showers, massage. Breathing techniques etc. all awesome ways. I have had three children, and I am pregnant with my fourth. With my first I had IV meds and an epidural. With my second, an epidural, and with my third, nothing, I did it natural. And since then, I have become a natural advocate! After having experienced birth three "ways", each varying on the pain meds used, I would go back and have a natural birth over again for the first two. There are Doulas or labor support professionals who work with women practicing comfort measures, relaxation techniques etc. and can make a huge difference. A good support person (for me it was my husband and my mom) can help you have a very satisfying and pain "managed" birth, without drugs. Best wishes! Answered by Troy Odgen 2 years ago.

Controlled Breathing I heard works, but in my opinion an epidural is the best option. It will hurt at first, but right after you have the epidural you won't feel a thing. The only thing you should feel is a slight pressure below signaling that you are about to deliver. I am glad I had the epidural because when I had my daughter, she ripped me up in 2 places. It helped me, but it is truly up to you. Answered by Grazyna Herbert 2 years ago.

There are other options, like one lady said, Demerol. But Demerol only lasts so long and you can still feel the pain, it just doesn't really bother you that much. I had no drugs with my first and it really hurt and it was hard to concentrate. With my son I had an epidural, and trust me they are worth it. You can push just fine, I was able to concentrate better and he was out in 20 min. The pain of the contractions are waaayyy worse than the pain of getting an epidural. Answered by Mathilde Stoffle 2 years ago.

Im going to use gas for mine. Some hospitals will give you Panadine Forte as an option. I heard that the bath is also really good. Have your baby in the bath at the hospital. Takes away from some of the pain too. There are alot of options. But in my opinion I wouldn't do an epidural. Causes complications in the future for you. EG: -Bladder Control. -Take longer for your private area to shrink and close up to original pre-pregnancy size. -etc... All these and more can happen because having an epidural they are taking away your ability to push and numbing your lower body so you can't feel anything. So if anything tears you won't know till after. They would have to clamp on to the baby and physically pull him/her out of you, cause you have lost your ability to push. You can always also look up different types of pain reliefs on the net, that's what it is there for. Or go ask a mid-wife. They will provide you with all the information your looking for. Good Luck! Answered by Ryann Wolsdorf 2 years ago.

There are diverse ideas. you may opt to flow by utilising way of complicated artwork utilising respiration and relax ideas. inspite of if, in case you want medical interventions, an epidural is a thanks to flow. There are diverse medical ideas at the same time with narcotics yet those on the instantaneous are not to any extent further as efficient as an epidural and motives drowsiness for both the mother and the toddler. the draw back to an epidural is that you'll now no longer have the skill to stroll round once you've one and it prolongs complicated artwork. diverse than that, the negative aspects are minimum. some women adventure decrease back pains for some weeks once you've the epidural. i'm planning on taking complicated artwork because it comes. i'm now no longer planning on getting an epidural yet i'm now no longer planning on refusing one both. If my respiration and relax ideas fail i'm in contact about getting an epidural. inspite of if, i imagine of it truly is going for use as a very last inn fairly than a popular selection. fairly is basically my opinion. each and every lady will take care of and flow by utilising way of complicated artwork in her very own way and no way is misguided. Answered by Yetta Morelock 2 years ago.

Narcotics, a saddle block, sterile water papules for back labor, in some countries women can get gas/air... Personally I had Nubain during one labor and it was really awful for me as it caused intense vertigo and didn't take the edge off as the nurse had promised. I had problems another time (not labor) when I was given Demerol so I am just not at all a believe in narcotics. ALSO, I think the Nubain made my baby so sleepy and she was really hard to nurse. Since then I've had two waterbirths and I just have to say that laboring in the water is AWESOME (and side effect free)! :) Answered by Elisa Economou 2 years ago.

I had no pain medicine at all when I gave birth. Ichose to control the pain through breathing and focusing. It still hurt pretty bad, but I am so glad I did it that way. If you feel you need something, there are plenty of IV options. Talk to your doctor. Answered by Maegan Boehner 2 years ago.

Bring in a picture or have someone or focus something in the rooom really hard. Don't think about anything but that one thing ure focusing on. It sometimes helps for some women. Answered by Dalila Rach 2 years ago.


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