Application Information

This drug has been submitted to the FDA under the reference 009386/001.

Names and composition

"MYLERAN" is the commercial name of a drug composed of BUSULFAN.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
009386/001 MYLERAN BUSULFAN TABLET/ORAL 2MG

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
009386/001 MYLERAN BUSULFAN TABLET/ORAL 2MG
020954/001 BUSULFEX BUSULFAN INJECTABLE/INJECTION 6MG per ML
202259/001 BUSULFAN BUSULFAN INJECTABLE/INJECTION 6MG per ML
205106/001 BUSULFAN BUSULFAN INJECTABLE/INJECTION 6MG per ML
207050/001 BUSULFAN BUSULFAN INJECTABLE/INJECTION 6MG per ML

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Answered questions

What happens if you have bone marrow suppression?
a patient has leukemia and is taking Myleran and has developed bone marrow suppression. which nursing diagnosis has the highest priority? activity intolerance altered peripheral tissue perfussion fluid volume deficit: hemorrhage infection Asked by Genna Filonuk 12 months ago.

i would prioritise hemoorhage, then perfusion, then infection and lastly activity intolerance, good luck Answered by Lovie Christeson 12 months ago.


Chronic myeloid lukemia?
do they use daunorubicin? or is that just for acute? what type of chemo is commonly used? links are appreciated. Asked by Pilar Malec 12 months ago.

Many times, CML causes no symptoms and is found only when a routine blood sample is checked. The most common symptom is severe fatigue. The person may also have unexplained weight loss and night sweats. Occasionally, the person can feel pain in the upper left side of the abdomen due to a swollen spleen. In most cases, the cause of CML is unknown. Some cases have been linked to exposure to high-dose radiation (such as the atomic bomb blasts in Japan) or to inherited abnormalities. Chemotherapy with medicines such as hydroxyurea (i.e., Hydrea) or busulfan (i.e., Myleran) may decrease the numbers of CML cells for many years. Interferon, a natural substance produced by white cells, may also help the body control the CML cells. Known as a biological response modifier, interferon does not cure the cancer. It can only control it for a period of time. Some people are given the bone marrow from another person to help recovery. This is called a bone marrow transplant. A bone marrow transplant during this phase may cure the person. This therapy is very intense and may not be right for every person who has CML. During the terminal phase, CML will be treated like acute leukemia. High doses of chemotherapy may be given intravenously. If the cancerous cells can be destroyed, a stage known as remission, the person may be considered for a bone marrow transplant. Remission is usually followed by additional therapy. The person with CML will need to be followed closely for signs of the disease worsening. Persons who have had a bone marrow transplant will need lifelong follow-up even if the disease is in remission. Good luck Answered by Cristine Jackel 12 months ago.

In the last 5 years treatment has turned away from standard therapies like hydroxyurea and chemotherapies to Tyrosine Kinase inihibitors like Gleevec (imatinib) and desatanib. I don't think daunomycin is used, except perhaps in the blast phase. Answered by Russell Creeley 12 months ago.

that's the main cancers of the myeloid (bone marrow or spinal twine) line of white blood cells (leuk=white, emia=blood concern) characterized by utilizing a rapid and frequently extreme develop of atypical cells interior the bone marrow and this interferes interior the production of well-known blood cells. that's the main elementary acute leukemia in adults. Answered by Marcellus Komatsu 12 months ago.


What is the major of chemotherapy agents in anti-cancer drugs ?
Asked by Sherrie Siphan 12 months ago.

There are many different chemotherapy agents. Different drugs work for different cancers, and they are frequently used in combination. You need to be more specific. Here is a list of chemo drugs: 13-cis-Retinoic Acid 2-CdA 2-Chlorodeoxyadenosine 5-Fluorouracil 5-FU 6-Mercaptopurine 6-MP 6-TG 6-Thioguanine Abraxane Accutane ® Actinomycin-D Adriamycin ® Adrucil ® Agrylin ® Ala-Cort ® Aldesleukin Alemtuzumab ALIMTA Alitretinoin Alkaban-AQ ® Alkeran ® All-transretinoic acid Alpha interferon Altretamine Amethopterin Amifostine Aminoglutethimide Anagrelide Anandron ® Anastrozole Arabinosylcytosine Ara-C Aranesp ® Aredia ® Arimidex ® Aromasin ® Arranon ® Arsenic trioxide Asparaginase ATRA Avastin ® Azacitidine BCG BCNU Bevacizumab Bexarotene BEXXAR ® Bicalutamide BiCNU Blenoxane ® Bleomycin Bortezomib Busulfan Busulfex ® C225 Calcium Leucovorin Campath ® Camptosar ® Camptothecin-11 Capecitabine Carac ™ Carboplatin Carmustine Carmustine wafer Casodex ® CC-5013 CCNU CDDP CeeNU Cerubidine ® Cetuximab Chlorambucil Cisplatin Citrovorum Factor Cladribine Cortisone Cosmegen ® CPT-11 Cyclophosphamide Cytadren ® Cytarabine Cytarabine liposomal Cytosar-U ® Cytoxan ® Dacarbazine Dacogen Dactinomycin Darbepoetin alfa Daunomycin Daunorubicin Daunorubicin hydrochloride Daunorubicin liposomal DaunoXome ® Decadron Decitabine Delta-Cortef ® Deltasone ® Denileukin diftitox DepoCyt ™ Dexamethasone Dexamethasone acetate Dexamethasone Sodium Phosphate Dexasone Dexrazoxane DHAD DIC Diodex Docetaxel Doxil ® Doxorubicin Doxorubicin liposomal Droxia ™ DTIC DTIC-Dome ® Duralone ® Efudex ® Eligard ™ Ellence ™ Eloxatin ™ Elspar ® Emcyt ® Epirubicin Epoetin alfa Erbitux ™ Erlotinib Erwinia L-asparaginase Estramustine Ethyol Etopophos ® Etoposide Etoposide Phosphate Eulexin ® Evista ® Exemestane Fareston ® Faslodex ® Femara ® Filgrastim Floxuridine Fludara ® Fludarabine Fluoroplex ® Fluorouracil Fluorouracil (cream) Fluoxymesterone Flutamide Folinic Acid FUDR ® Fulvestrant G-CSF Gefitinib Gemcitabine Gemtuzumab ozogamicin Gemzar ® GleevecTM Gliadel wafer (t) GM-CSF Goserelin granulocyte - colony stimulating factor (t) Granulocyte macrophage colony stimulating factor (o) Halotestin (t) Herceptin (t) Hexadrol (t) Hexalen (t) Hexamethylmelamine (t) HMM (t) Hycamtin (t) Hydrea (t) Hydrocort Acetate (t) Hydrocortisone Hydrocortisone sodium phosphate Hydrocortisone sodium succinate Hydrocortone phosphate (t) Hydroxyurea Ibritumomab Ibritumomab Tiuxetan Idamycin ® Idarubicin Ifex ® IFN-alpha Ifosfamide IL-11 IL-2 Imatinib mesylate Imidazole Carboxamide Interferon alfa Interferon Alfa-2b (PEG conjugate) (o) Interleukin - 2 (t) Interleukin-11 (o) Intron A® (interferon alfa-2b) Iressa ® Irinotecan Isotretinoin Kidrolase (t) Lanacort (t) L-asparaginase (t) LCR (o) Lenalidomide Letrozole Leucovorin Leukeran (t) Leukine (t) Leuprolide Leurocristine (o) Leustatin (t) Liposomal Ara-C (t) Liquid Pred (t) Lomustine L-PAM (o) L-Sarcolysin (o) Lupron (t) Lupron Depot ® Matulane (t) Maxidex (t) Mechlorethamine Mechlorethamine Hydrochloride Medralone (t) Medrol ® Megace (t) Megestrol Megestrol Acetate (o) Melphalan Mercaptopurine Mesna Mesnex (t) Methotrexate Methotrexate Sodium (o) Methylprednisolone Meticorten (t) Mitomycin Mitomycin-C (o) Mitoxantrone M-Prednisol (t) MTC (o) MTX (o) Mustargen (t) Mustine Mutamycin (t) Myleran (t) Mylocel (t) Mylotarg (t) Navelbine ® Nelarabine Neosar (t) Neulasta (t) Neumega (t) Neupogen ® Nexavar ® Nilandron (t) Nilutamide Nipent ® Nitrogen Mustard (o) Novaldex (t) Novantrone (t) Octreotide Octreotide acetate (o) Oncospar (t) Oncovin (t) Ontak (t) Onxal (t) Oprevelkin Orapred (t) Orasone (t) Oxaliplatin Paclitaxel Paclitaxel Protein-bound Pamidronate Panretin (t) Paraplatin (t) Pediapred (t) PEG Interferon Pegaspargase Pegfilgrastim PEG-INTRON (t) PEG-L-asparaginase PEMETREXED Pentostatin Phenylalanine Mustard (o) Platinol (t) Platinol-AQ (t) Prednisolone Prednisone Prelone (t) Procarbazine PROCRIT ® Proleukin (t) Prolifeprospan 20 with Carmustine implant (t) Purinethol ® Raloxifene Revlimid ® Rheumatrex (t) Rituxan (t) Rituximab Roferon-A® (interferon alfa-2a) Rubex (t) Rubidomycin hydrochloride (t) Sandostatin ® Sandostatin LAR (t) Sargramostim Solu-Cortef (t) Solu-Medrol (t) Sorafenib STI-571 Streptozocin SU11248 Sunitinib Sutent ® Tamoxifen Tarceva ® Targretin (t) Taxol ® Taxotere ® Temodar ® Temozolomide Teniposide TESPA (o) Thalidomide Thalomid ® TheraCys (t) Thioguanine Thioguanine Tabloid ® Thiophosphoamide (o) Thioplex (t) Thiotepa TICE ® Toposar (t) Topotecan Toremifene Tositumomab Trastuzumab Tretinoin Trexall (t) Trisenox (t) TSPA (o) VCR (o) Velban (t) Velcade ® VePesid (t) Vesanoid (t) Viadur (t) Vidaza (t) Vinblastine Vinblastine Sulfate (o) Vincasar Pfs (t) Vincristine Vinorelbine Vinorelbine tartrate (o) VLB (o) VM-26 (o) VP-16 (t) Vumon (t) Xeloda ® Zanosar (t) Zevalin TM Zinecard (t) Zoladex ® Zoledronic acid Zometa ® See? There's a lot of them. Answered by Loree Criscuolo 12 months ago.

antineoplastics, monoclonal antibodies, Answered by Tamekia Tellio 12 months ago.

Please see the webpages for more details on Chemotherapy. Answered by Daisy Krumenauer 12 months ago.


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