How well does Modafinil work?
For the past several years I have been exhausted during the day time, to the point where I can't hold open my eyes. My doctors aren't finding anything significant wrong with me, and we think it's my long term use of an anti depressant that is causing it. How well does Modafinil/Provigil work? ...
Asked by Nancy Snowdon 6 months ago.
For the past several years I have been exhausted during the day time, to the point where I can't hold open my eyes. My doctors aren't finding anything significant wrong with me, and we think it's my long term use of an anti depressant that is causing it. How well does Modafinil/Provigil work? Will I really feel awake during the day? Answered by Emily Sobota 6 months ago.
Modafinil is used to treat excessive sleepiness caused by narcolepsy (a condition that causes excessive daytime sleepiness) or shift work sleep disorder (sleepiness during scheduled waking hours and difficulty falling asleep or staying asleep during scheduled sleeping hours in people who work at night or on rotating shifts). Modafinil is also used along with breathing devices or other treatments to prevent excessive sleepiness caused by obstructive sleep apnea/hypopnea syndrome (OSAHS; a sleep disorder in which the patient briefly stops breathing or breathes shallowly many times during sleep and therefore doesn't get enough restful sleep). Modafinil is in a class of medications called wakefulness promoting agents. It works by changing the amounts of certain natural substances in the area of the brain that controls sleep and wakefulness. Please see the web pages for more details on Modafinil (generic name) Provigil (brand name). Answered by Eula Bruender 6 months ago.
Im also on antidepressants and modafinil. Yes it does a great job!! I ll take 200mg in the morning then i have lots of energy for 12-15 hours For me it was really hard to stay awake during the day and it really changed my life If you decide to take it it may take a week for full effect but you ll feel it from day 1 also good nutrition makes a big difference. Hope this helps Answered by Caroyln Cervoni 6 months ago.
Does Modafinil Work Answered by Eulah Mcglumphy 6 months ago.
Modafinil is not a long term solution. You have a sleep disorder problem and Modafinil is not a quick fix. It interferes with your sleep/wake cycle and the part of your brain that controls it. Your sleepy during the day because you are not getting restful sleep. You may think you are sleeping but there is a diffference between falling asleep and getting the healthy restful sleep in which you are going through all sleep stages. Your anti-depressant is affecting that. Are you still using your anti-depressant? Maybe you can be switched to a different type or you can curb it. Depression is like any other psychiatric illness which involves a multifactorial approach to care besides just medicine. You need to eat healthier and exercise. You also need to develop positive relationships. If there are issues with your job or family, you need to address that as well. All of those factors in addition to medicine will help you overcome your depression and enable you to sleep. I know a lot of depressed patients that don't alter their lifestyle and just depend on medication. Those patients don't do as well as those who take meds and improve their diet, exercise and relationships. They are all important. I would also see a therapist (psychiatrist or psychologist) on a regular basis so you address these issues. Have you had a sleep study done? I would consider getting one of those performed as well to see if you are sleeping properly in the night. But before I would get a sleep study, I would try to improve those other facts first: diet, exercise, relationships and job. You will be suprised. If you improve those factors, you will probably need less medication and will probably sleep better and feel more rested. Answered by Lelah Reth 6 months ago.
Im additionally utilising modafinil i take 2 hundred interior the morning because of fact its lively 15 hours so i cant sleep if i take it previous due. to confirm outcomes with modafinil some human beings prefer 2 or 3 weeks so wait and notice Answered by Trista Turell 6 months ago.
Does anyone take, or ever tried, Provigil/Modafinil, Nuvigil/Armodafinil, Modalert, or Waklert?
If so, how exactly does it affect you? How long does it last? How long does it take to kick in? What dosage do you take daily? Does your body build a tolerance to it?
Asked by Fleta Rowback 6 months ago.
Modafinil ... It rocks! 200 mg in the morning. Takes about 20-30 minutes to kick in. Modafinil and similar drugs promote wakefulness and alertness by getting rid of the "tired feeling." You know how you feel when you feel tired? Of course you do! Modafinil makes that feeling go away! So you don't feel tired and have more energy. Lasts about 12 hours. Does not interfere with sleep - you can sleep when you want to. The only "interference" is that you may not want to! In short, it's everyone's dream drug. Grab the chance to take it. Answered by Allison Goossens 6 months ago.
I took Modafinil for a while as I wanted to try something that help with cognition. It gives you a slight buzz and the buzz feels real chemically. If your a bit on the lazy side or procrastinate a lot, Modafinil is great. Within half an hour of taking it, you'll have sat down and be working on whatever it is you kept putting off. it does turn you into a bit of a zombie though. There was times that I took it and then worked for 12 hours straight but it's not like other stimulants where you fly through work. With modafinil, you work at a moderate but steady pace. In the end I stopped taking it as I was awake sometimes for days without sleep which in itself isn't that bad but it kind of messed up my sleep cycle.Since I stopped taking it as well I've developed a small rash on my chest that I cannot get rid of. Because of that I'm not planning on taking it again. Answered by Paul Auter 6 months ago.
Provigil Modafinil Side Effects ?...Can anyone please tell me.?
Asked by Vi Lafoon 6 months ago.
The following webpage states about Provigil (Modafinil): "Before taking this medicine You should not use Provigil if you are allergic to modafinil or armodafinil (Nuvigil). To make sure you can safely take Provigil, tell your doctor if you have any of these other conditions: > angina (chest pain); > cirrhosis or other liver problem; > kidney disease; > a heart muscle or valve disorder such as mitral valve prolapse; > a history of drug addiction; > if you take blood pressure medications; or > if you have recently had a heart attack. Skin rashes serious enough to require hospitalization have occurred in people using a medicine similar to Provigil. These rashes usually occurred within 1 to 5 weeks after the first dose. Stop taking Provigil and call your doctor at the first sign of any skin rash, no matter how minor you think it might be. FDA pregnancy category C. It is not known whether Provigil will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether modafinil passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Provigil can make certain types of birth control pills less effective, which could result in an unplanned pregnancy. Talk with your doctor about the best methods of birth control to use while taking this medicine." "Provigil side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Provigil and call your doctor at once if you have any of these serious side effects: > fever, sore throat, headache, and vomiting with a severe blistering, peeling, and red skin rash; > bruising, severe tingling, numbness, pain, muscle weakness; > easy bruising or bleeding; > white patches or sores inside your mouth or on your lips; > hallucinations, unusual thoughts or behavior; > depression, anxiety, aggression; or > chest pain, uneven heart beats. Less serious Provigil side effects may include: > headache, dizziness; > feeling nervous or agitated; > nausea, diarrhea; > trouble sleeping (insomnia); or > dry mouth." Answered by Stanton Bauknecht 6 months ago.
I had problems with dry mouth when I started taking Provigil. I take it in divided doses, so if I put the doses too close together it sometimes causes dry mouth still and I talk too much. If I take it too close to bedtime, it makes the insomnia unbearable. Otherwise, I haven’t had ANY problems and have been on the medicine for over seven years. Answered by Beckie Gustave 6 months ago.
HAS ANYBODY TRIED MODAFINIL FOR DEPRESSION ?
hOW DID YOU GET ON WITH IT?
Asked by Renita Gundert 6 months ago.
I am currently on Modafinil and doing really fine. It is a myth that antidepressants actually stimulate those who are depressed. As Dr. David Healy writes in his book 'Psychiatric Drugs Explained', had psychiatrists in the 50's and 60's expected antidepressants to stimulate the depressed patient, antidepressants would not have developed beyond that time. Modafinil is especially useful in cases where the existing feelings of the patient are one of lethargy, hypersomnia, lack of motivation, anergia, in other words, not really a depressed mood (which could be an indication of Bipolar Disorder). Modafinil apart from the classical effect of making the patient awake and alert, actually helps "clear the head", so that the therapy becomes more effective. The only caution here is that if the patient becomes restless, paces the floor, Modafinil is just not doing "job'. Answered by Nikita Scoggin 6 months ago.
Is nefiracetam a more efficacious nootropic than the eugeroics, such as modafinil, armodafinil, or adrafinil?
Asked by Christene Aspegren 6 months ago.
Yes, nefiracetam is more effective than the ampakines (e.g., adrafinil, armodafinil, modafinil) for cognitive and memory enhancement, and all are more effective than such stimulants as caffeine and theophylline. The word nootropic was coined upon discovery of the effects of piracetam, developed in the 1960s. Although piracetam is the most commonly taken nootropic, there are many relatives in the family which have different potencies and side effects. Other commom racetams include pramiracetam, oxiracetam, and aniracetam. There is no generally accepted mechanism for racetams. They generally show no affinity for the most important receptors, although modulation of most important central neurotransmitters have been reported, including acetylcholine and glutamate. Although aniracetam and nebracetam show affinity for muscarinic receptors, only nefiracetam shows it at the nanomolar range. Racetams have been called "pharmacologically safe" drugs. Nootropics, also referred to as smart drugs, memory enhancers, and cognitive enhancers, are drugs, nutraceuticals, brain food and functional foods that are purported to improve human cognitive abilities. Eugeroics ("wakefulness enhancers") are a key category of stimulants. Although their primary biochemical mechanisms are unproven, their efficacy is well documented. Of the three major eugeroics, armodafinil may ultimately prove to be the most efficacious, since its stereochemistry is more bioactive than the racemic modafinil. Modafinil, in turn, is more efficacious than adrafinil, which is more slowly metabolized. Modafinil (Provigil/Alertec/Modavigil) is a stimulant drug manufactured by Cephalon, and is approved by the FDA for the treatment of narcolepsy, shift work sleep disorder, and excessive daytime sleepiness associated with obstructive sleep apnea. Modafinil, like other stimulants, increases the release of monoamines, but also elevates hypothalamic histamine levels, leading some researchers to consider Modafinil a "wakefulness promoting agent" rather than a classic amphetamine-like stimulant (as evidenced by the difference in c-fos distribution caused by modafinil as compared to amphetamine). Although modafinil is thought to be effective in the treatment of Attention-Deficit Hyperactivity Disorder (ADHD), in 2006 it was specifically rejected by the FDA for use by children for that purpose after Cephalon was rebuffed in its effort to introduce modafinil as a children's drug under the trade name, Sparlon. Cephalon's own label for Provigil now discourages its use by children for any purpose. Armodafinil (Nuvigil) is a stimulant-like drug produced by the pharmaceutical company Cephalon Inc., which was approved by the FDA on June 15, 2007. Armodafinil is the active (−)-(R)-enantiomer of the racemic drug modafinil (Provigil). Cephalon plans to conduct clinical trials evaluating the use of Nuvigil as a treatment for serious medical conditions such as bipolar depression, cognition associated with schizophrenia, and excessive sleepiness and fatigue in conditions such as Parkinson's disease and cancer, but it is still in the clinical testing stage. Adrafinil is a mild central nervous system stimulant drug used to relieve excessive sleepiness and inattention in elderly patients. It is also used off-label by individuals wishing to avoid fatigue, such as night workers or others who need to stay awake and alert for long periods of time. Adrafinil is a prodrug; it is primarily metabolized in vivo to modafinil (Provigil), resulting in nearly identical pharmacological effects. Unlike modafinil, however, it takes time for the metabolite to accumulate to active levels in the bloodstream. Effects usually are apparent within 45-60 minutes when taken orally on an empty stomach. Answered by Alishia Fouquet 6 months ago.
Adrafinil Wiki Answered by Rich Adjei 6 months ago.
Why does Provigil aka modafinil make me pass out?
I've been on Provigil for about a week and half. At first it woke me up and helped me. Now when I wake up in the morning and take it, I pass out an hour later. Can anyone help me?
Asked by Virgil Lanes 6 months ago.
Have you changed your sleep schedule since you started taking it? Modafinil side-effects do not include somnolence. However people taking a legal prescription are by the very definition - already suffering from somnolence (sleepiness). It takes 2-3 hours for Modafinil to reach peak absorption into your body. Falling asleep within minutes of taking it indicates a psycho-somatic trigger, not the medication. Modafinil works if you maintain a normal sleep schedule. It helps you to adjust your sleep-schedule throughout your week. It's primary action is as a circadian-clock "reset button", not a stimulant. It does not help you be less tired if you are getting insufficient sleep. So if you are attempting to use Modafinil as a replacement for sleep - then yes, you're going to pass out. Many people who take black-market provigil to party-hard or cram for exams quickly find this out. I've been taking it for over a decade due to day/night reversal for my acute liver disease. Day/night reversal for me is waking up every day at 2am or 3am, no matter what time I go to bed. I still need five or six hours a sleep a night. If I do not get enough sleep, I'll be tired, and even fall asleep, even after taking Modafinil. To be effective, you need to get your normal amount of sleep each day - 7 to 9 hours for most people, 5 to 6 hours for the 15% of people with the low-sleep genetic phenotype. It's not possible to abuse Modafinil and not-sleep, your body can't do that. Answered by Deborah Glick 6 months ago.