METHADONE HYDROCHLORIDE Ressources

Application Information

This drug has been submitted to the FDA under the reference 006383/002.

Names and composition

"METHADONE HYDROCHLORIDE" is the commercial name of a drug composed of METHADONE HYDROCHLORIDE.

Answered questions

Difference between Methadone Hydrochloride and Methadone?
my mom went and got her monthly pills and its a different methadone its says "hydrochloride" after methadone and it looks different Asked by Lorraine Gendler 4 months ago.

It's the same sort of thing. The active ingredient, the methadone, is the only real thing you need to worry about. The hydrochloride is just a chemically bonded chloride group that shouldn't affect the methadone whatsoever. Methadone comes with hydrochloride generally, so chances are the labels that you had before only listed the main ingredient, methadone, and recently with newer rules about being specific of the whole ingredient they are now mandated to say hydrochloride. Overall, no difference. Answered by Lekisha Campana 4 months ago.

Methadone Hydrochloride Answered by Venetta Mada 4 months ago.

Methadone Hcl Answered by Sharla Matesic 4 months ago.

they are pills Answered by Gisela Abadie 4 months ago.


Methadone what are the side affects to the unborn child?
a pregnant mother to be on methadone Asked by Jodee Vieira 4 months ago.

Methadone hydrochloride is a pregnancy risk category C drug. Drugs in category C are those that have shown adverse effects in studies done on animals but there are no controlled studies in women or the studies are not yet available. Drugs in this category should be given only if the potential benifits outweigh the potential risks to the fetus. Whoever this is needs to discuss this at length with a physician immediately. Answered by Elke Arcino 4 months ago.

I know a girl who took methadone the whole pregnancy and her baby was in the hospital for months after he was born going through withdrawals and now he hits and bites everyone he definitely has developmental problems Answered by Hisako Pavlicek 4 months ago.


What are the doses of methadone that should be takin and how often?
Thanks for helping me you ***** Asked by Shoshana Morefield 4 months ago.

Methadone is available for pain control only in 5mg & 10mg Tablets. As far as recommending a dose and schedule that should be decided by your doctor. If your presctiption is unclear you should contact your pharmacy or physician. However, thereis some info. I can give you that sometimes doctor either don't give or don't know. This lack of understanding has caused deaths to occur in certain situations.This is a serious medication with serious consequences if taken wrong. Here is some important info that may help save your life and should have been given to you by your doctor... Methadone can cause life threatening breathing problems which can lead to death. These problems are more likely to happen when methadone is first started or in someone who is not already taking other narcotic (opioid) pain medicines. It is very important that you take Methadone Hydrochloride Oral Solution exactly as your doctor has prescribed. Methadone stays in the system long after the pain has returned. Do not increase your Methadone on your own or take additional medications if you feel it is not working. Methadone can react with medication even 48hrs after taking a dose. Talk to your doctor about your pain. Your doctor can decide if your methadone dose needs to be changed. Prevent theft and misuse. Keep your Methadone in a safe place to protect it from theft. Never give Methadone to anyone else even if they have the same symptoms you have. It may harm them and even cause death. Selling or giving away this medicine is dangerous and against the law. Methadone is used: to treat moderate to severe pain in people that do not respond to non-narcotic pain medicines; to control withdrawal symptoms in patients being treated for narcotic drug addiction; for maintenance treatment of narcotic drug addiction along with other social and medical services. Stopping maintenance treatment of narcotic drug addiction with methadone may result in a return to narcotic drug use. Who Should Not Take Methadone ? Do not take Methadone if you: have severe asthma or severe lung problems. have a blockage or obstruction in your intestines. are allergic to methadone or anything else in Methadone What Should I Tell my Doctor Before I Start Taking Methadone Hydrochloride Oral Solution? Methadone may not be right for you. Before starting Methadone , tell your doctor about all your medical and mental conditions including a history of drug or alcohol abuse or addiction. Tell your doctor if you: Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Some medicines may cause serious or life-threatening medical problems when taken with Methadone Hydrochloride Oral Solution. Be especially careful about other medicines that may make you sleepy, such as other pain medicines, anti-depressant medicines, sleeping pills, anxiety medicines, antihistamines, or tranquilizers. Sometimes, the doses of certain medicines (including methadone) may need to be changed if they are used together. Don't take Methadone with antidepressants or benzodiazepines (Xanax, Valium, Klonipin, etc) Do not take any medicine while using Methadone until you have first talked to your doctor or pharmacist. They will be able to tell you if it is safe to take other medicines while you are using methadone. Know the medicines you take. Keep a list of your medicines and show it to your doctor and pharmacist each time you get a new medicine. Take Methadone exactly as prescribed. Follow your doctor’s directions exactly. Your doctor may change your dose based on your reactions to the medicine. Do not change your dose unless your doctor tells you to change it. Do not take a higher dose of Methadone Hydrochloride Oral Solution or take it more often than prescribed. This can lead to an overdose and possibly death. If you take too much methadone or overdose, call 911 or your local emergency number right away. Review your medical conditions regularly with your doctor to determine if you still need Methadoneor if the dose needs to be adjusted. When starting treatment with Methadone for narcotic drug dependence, you should be aware that your dose of methadone will “hold” for longer periods of time as treatment goes on. Stopping Methadone . Ask your doctor for instructions on how to stop this medicine slowly to avoid uncomfortable symptoms. You should not stop taking Methadone all at once if you have been taking it for more than a few days. Tell all health professionals that treat you that you take methadone. After stopping treatment with Methadone flush the unused liquid down the toilet. What Should I Avoid While Taking Methadone ?Do not drink alcohol while using Methadone Hydrochloride Oral Solution. It may increase the chance of having dangerous side effects. Do not take other medicines with without first talking with your doctor. What are the Possible Side Effects of Methadone ? Call your doctor or get medical help right away if you: have trouble breathing. have extreme drowsiness and breathing slows down. have slow shallow breathing (little chest movement with breathing). fast or slowed heartbeat. feel faint, very dizzy, confused, have palpitations (irregular heart beat) or any other unusual symptoms. These can be symptoms that you have taken too much (overdose of) Methadone , or the dose is too high for you. They can also be symptoms of a serious heart reaction. These symptoms can lead to serious problems or death if not treated right away. Methadone can cause your blood pressure to drop. This can make you feel dizzy if you get up too fast from sitting or lying down. Methadone can cause physical dependence. Do not stop taking methadone or any other opioid without first talking to your doctor. You could become sick with uncomfortable withdrawal symptoms because your body has become used to these medicines. Talk to your doctor about slowly stopping Methadone to avoid getting sick with withdrawal symptoms. Physical dependency is not the same as drug addiction. For patients using Methadone for pain treatment, there is a chance of abuse or addiction with methadone. The chance is higher if you are or have been addicted to or abused other medicines, street drugs, or alcohol, or if you have a history of mental problems. Some common side effects of methadone are lightheadedness, dizziness, drowsiness, nausea, vomiting and sweating. Other side effects include weakness, headache, constipation, itching, and dry mouth. Talk to your doctor about any side effects that bother you or that do not go away. These are not all the possible side effects of methadone. For a complete list, ask your doctor or pharmacist. How Should I Store Methadone ? Keep Methadone in a safe place away from children. Accidental use by a child is a medical emergency that can result in death. If a child accidentally takes methadone, get emergency help right away. Keep Methadone Hydrochloride Oral Solution at room temperature, 59 to 86°F (15 to 30°C). Always keep Methadone in a secure place to protect from theft. Dispose of any unused Methadone remaining from a prescription as soon as it is no longer needed. Unused liquid should be flushed down the toilet. General Information About Methadone. Medicines are sometimes prescribed for purposes other than those listed in patient information leaflet. Do not use methadone for a condition for which it was not prescribed. Do not give methadone to other people, even if they have the same symptoms you have. Methadone can harm other people and even cause death. Sharing methadone is against the law. I know this is a lot but it is better to be safe than sorry. Answered by Brian Newkirk 4 months ago.

Methadone is really not used for pain control. It is a substitute for heroin withdrawals. There are much better medications available for pain. Talk to your doctor. Not getting it from your doctor is ILLEGAL. Answered by Shane Beherns 4 months ago.


What is the proper time dosing of methadone Dr never said..just said 3aday?
on the bottle said 3 aday Asked by Wilburn Hagemeier 4 months ago.

Usually when something is prescribed three times a day it is to be taken every 8 hours. 8x3=24 I am concerned that a doctor gave you a script for Methadone without educating you on it. This is a serious medication with serious consequences if taken wrong. Here is some important info that may help save your life and should have been given to you by your doctor... Methadone can cause life threatening breathing problems which can lead to death. These problems are more likely to happen when methadone is first started or in someone who is not already taking other narcotic (opioid) pain medicines. It is very important that you take Methadone Hydrochloride Oral Solution exactly as your doctor has prescribed. Methadone stays in the system long after the pain has returned. Do not increase your Methadone on your own or take additional medications if you feel it is not working. Methadone can react with medication even 48hrs after taking a dose. Talk to your doctor about your pain. Your doctor can decide if your methadone dose needs to be changed. Prevent theft and misuse. Keep your Methadone in a safe place to protect it from theft. Never give Methadone to anyone else even if they have the same symptoms you have. It may harm them and even cause death. Selling or giving away this medicine is dangerous and against the law. Methadone is used: to treat moderate to severe pain in people that do not respond to non-narcotic pain medicines; to control withdrawal symptoms in patients being treated for narcotic drug addiction; for maintenance treatment of narcotic drug addiction along with other social and medical services. Stopping maintenance treatment of narcotic drug addiction with methadone may result in a return to narcotic drug use. Who Should Not Take Methadone ? Do not take Methadone if you: have severe asthma or severe lung problems. have a blockage or obstruction in your intestines. are allergic to methadone or anything else in Methadone What Should I Tell my Doctor Before I Start Taking Methadone Hydrochloride Oral Solution? Methadone may not be right for you. Before starting Methadone , tell your doctor about all your medical and mental conditions including a history of drug or alcohol abuse or addiction. Tell your doctor if you: Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Some medicines may cause serious or life-threatening medical problems when taken with Methadone Hydrochloride Oral Solution. Be especially careful about other medicines that may make you sleepy, such as other pain medicines, anti-depressant medicines, sleeping pills, anxiety medicines, antihistamines, or tranquilizers. Sometimes, the doses of certain medicines (including methadone) may need to be changed if they are used together. Don't take Methadone with antidepressants or benzodiazepines (Xanax, Valium, Klonipin, etc) Do not take any medicine while using Methadone until you have first talked to your doctor or pharmacist. They will be able to tell you if it is safe to take other medicines while you are using methadone. Know the medicines you take. Keep a list of your medicines and show it to your doctor and pharmacist each time you get a new medicine. Take Methadone exactly as prescribed. Follow your doctor’s directions exactly. Your doctor may change your dose based on your reactions to the medicine. Do not change your dose unless your doctor tells you to change it. Do not take a higher dose of Methadone Hydrochloride Oral Solution or take it more often than prescribed. This can lead to an overdose and possibly death. If you take too much methadone or overdose, call 911 or your local emergency number right away. Review your medical conditions regularly with your doctor to determine if you still need Methadoneor if the dose needs to be adjusted. When starting treatment with Methadone for narcotic drug dependence, you should be aware that your dose of methadone will “hold” for longer periods of time as treatment goes on. Stopping Methadone . Ask your doctor for instructions on how to stop this medicine slowly to avoid uncomfortable symptoms. You should not stop taking Methadone all at once if you have been taking it for more than a few days. Tell all health professionals that treat you that you take methadone. After stopping treatment with Methadone flush the unused liquid down the toilet. What Should I Avoid While Taking Methadone ?Do not drink alcohol while using Methadone Hydrochloride Oral Solution. It may increase the chance of having dangerous side effects. Do not take other medicines with without first talking with your doctor. What are the Possible Side Effects of Methadone ? Call your doctor or get medical help right away if you: have trouble breathing. have extreme drowsiness and breathing slows down. have slow shallow breathing (little chest movement with breathing). fast or slowed heartbeat. feel faint, very dizzy, confused, have palpitations (irregular heart beat) or any other unusual symptoms. These can be symptoms that you have taken too much (overdose of) Methadone , or the dose is too high for you. They can also be symptoms of a serious heart reaction. These symptoms can lead to serious problems or death if not treated right away. Methadone can cause your blood pressure to drop. This can make you feel dizzy if you get up too fast from sitting or lying down. Methadone can cause physical dependence. Do not stop taking methadone or any other opioid without first talking to your doctor. You could become sick with uncomfortable withdrawal symptoms because your body has become used to these medicines. Talk to your doctor about slowly stopping Methadone to avoid getting sick with withdrawal symptoms. Physical dependency is not the same as drug addiction. For patients using Methadone for pain treatment, there is a chance of abuse or addiction with methadone. The chance is higher if you are or have been addicted to or abused other medicines, street drugs, or alcohol, or if you have a history of mental problems. Some common side effects of methadone are lightheadedness, dizziness, drowsiness, nausea, vomiting and sweating. Other side effects include weakness, headache, constipation, itching, and dry mouth. Talk to your doctor about any side effects that bother you or that do not go away. These are not all the possible side effects of methadone. For a complete list, ask your doctor or pharmacist. How Should I Store Methadone ? Keep Methadone in a safe place away from children. Accidental use by a child is a medical emergency that can result in death. If a child accidentally takes methadone, get emergency help right away. Keep Methadone Hydrochloride Oral Solution at room temperature, 59 to 86°F (15 to 30°C). Always keep Methadone in a secure place to protect from theft. Dispose of any unused Methadone remaining from a prescription as soon as it is no longer needed. Unused liquid should be flushed down the toilet. General Information About Methadone. Medicines are sometimes prescribed for purposes other than those listed in patient information leaflet. Do not use methadone for a condition for which it was not prescribed. Do not give methadone to other people, even if they have the same symptoms you have. Methadone can harm other people and even cause death. Sharing methadone is against the law. I know this is a lot but it is better to be safe than sorry. Answered by Teisha Maw 4 months ago.

Methadone is normally for pain as needed.. If it doesn't specify a safe bet would be 4-6hours. Be very very careful Methadone can become very addictive quickly!! Answered by Drucilla Hussaini 4 months ago.

did you look at the prescription bottle, can you read it ??? if not, did you ask the pharmasist ??? call the Dr back and ask him/her... Answered by Delora Sages 4 months ago.


In each teaspoon of methadone what are the mg ?
Is there 5 mg 10 mg 20mg in each teaspoon of the liquid methadone like the pill is 5 mg or 10mg Asked by Corazon Inloes 4 months ago.

1mg methadone hydrochloride in 1ml of liquid 1 teaspoon is 4.9 ml Therefore there is approximately 5mg or precisely 4.9mg in one teaspoon of liquid methadone. Answered by Katharina Nilson 4 months ago.

The answer that says 1 teaspoon of liquid methadone is equal 5 mg's of methadone makes no sense whatsoever! That would mean that someone who is on a daily dose of 120 mg's would have to take 21 teaspoons of liquid methadone. On the other hand, a good friend of mine is on 120 mg of liquid methadone daily. He gets take homes, and each bottle of 120 mg's measures out to 2 teaspoons and a little bit more. This fully supports the 50 mg per teaspoon theory. Answered by Celsa Arkell 4 months ago.

For most methadone formulas the correct answer is 50mg. However it depends on what kind of liquid it is, there is a weaker formula which is 10mg or 5mg per teaspoons. My roommate has take homes on methadone and his dose is 150mg which is a tablespoon. 3 teaspoons equal 1 tablespoon so 1/3 of 150 is 50. Depending on the formula its either 50, 5mg or 10mg. I have included the government website showing 1ml equals 50mg & another sites showing the weaker dose of 10mg or 5mg per teaspoon. If the medication comes from a rehab clinic it is always 50mg per teaspoon only rx from a doctor may or may not be the lower version Answered by Ed Kotonski 4 months ago.

Methadone Milligrams Answered by Alissa Mckague 4 months ago.


Methadone????
I have had enough of being on Methadone.I've been on 25mg for 2weeks now cause when i went down to 15 the pain was unbearable.What I like to no is how long is the withdrawal(cold turkey) symptoms last?What can I do to ease them (home remedies)?I'm just so sick of this **** having control over my... Asked by Rocio Ozment 4 months ago.

I have had enough of being on Methadone.I've been on 25mg for 2weeks now cause when i went down to 15 the pain was unbearable.What I like to no is how long is the withdrawal(cold turkey) symptoms last?What can I do to ease them (home remedies)?I'm just so sick of this **** having control over my life.I'm sick of week after week someone watching me take a piss.I don't feel very sober being on this stuff and I want to be free of it for good...I ask about the withdrawals cause I have 7mo old twin girls and cant really be out of commision to long I have help at night time but not during the day.So can someone offer any advice or relief???? Answered by Tammi Firsching 4 months ago.

first off let me say i truly feel your pain and am sorry for what you have to go through. methadone is a legally prescribed drug but the withdrawals and dependence can be worse than the opiates its meant to replace. going cold turkey the withdrawals typically last longer than heroin or pharmaceutical opiates, i would say a few weeks to a month with a tapering of symptoms after the first week. there is something about methadone and bone pain, especially in the legs and lower back. this is typical with all opiate withdrawal but is definitely more pronounced and longer lasting with methadone. although you said the drop in 10mg was unbearable a gradual ween is your best bet, although hard it is easier than cold turkey. personally i hate methadone and what it does to you. i would strongly recommend talking to a detox/withdrawal doctor and learn about subutex or suboxone, these contain buprenorphine hydrochloride. subutex contains only buprenorphine hydrochloride. suboxone contains an additional ingredient called naloxone to guard against misuse. subutex is given during the first few days of treatment, while suboxone is used during the maintenance phase of treatment. this is a maintenance program like methadone but with a individually designed, 100% eeasier (physically and mentally) gradual ween. it does not make it painless but so much better than anything else. it is a little expensive if not covered by insurance but it is prescribed by a doctor so you can get your bi-weekly or monthly prescription at a pharmacy, you visit the doctor monthly (usually more often in the first month), and nobody watches you pee, they just take some blood in the beginning and sometimes during maintenance. now if all this is not in your means or you just really want the drugs completely out of you body asap then cold turkey is the way. i believe the only benefit to this method is that by experiencing the severe agony and pain, and the remembrance of this, it is is a strong psychological tool for staving off relapse, but that's it. cold turkey can be physically harmful to your body and have dangerous medical repercussions. a doctors advice is strongly recommended. if you decide this route, one of the best home remedies is Imodium, you will probably need it for the side effects of withdrawal anyway. this contains loperamide, it is a opioid receptor agonist which does not cross the blood brain barrier in a large enough amount to cause euphoria but it does lessen the withdrawal severity when taken at higher does. search wikipedia and erowid or just search loperamide and find out all you can about other peoples experiences using it. anxiety and stress meds help alot too, like xanax or valium but always keep in mind that these are only being used to get you away from a greater evil and must be used as a tool not a crutch. and although illegal, marijuana aids in easing the pain and physical effects (nausea, cramps etc.), but with the twins to take care of i dont believe it to be the best answer, depends where you stand on that issue. so that's what i got, make sure you search the hell out of this topic because the Internet has loads of information and support for what you are about to go through. you are very brave, know that you are always strong enough, and the pain and suffering is only temporary, the depression will last the longest and linger up to a year gradually fading but there is a very bright light at the end and is definitely within your grasp the whole time. i really know how bad it is, like dying a slow death only at the end you begin a gradual rebirth that is so much better. hope this helps. Answered by Pansy Czaja 4 months ago.

The most common method of methadone detox is "taper down therapy." Methadone doses are reduced incrementally until the patient is weaned off the drug. Unfortunately, patients still experience the debilitating withdrawal syndrome and often relapse into opiate drug use within the first year of detoxification. Withdrawal from methadone can take up to a month or even longer, whereas withdrawal from heroin takes seven to ten days. The effects of methadone last longer than those of morphine-based drugs. Many former heroin users have claimed that the horrors of heroin withdrawal were far less painful and difficult than withdrawal from methadone. Rapid detox is the most recent entry into the field of opiate detoxification. It treats opiate dependency at the receptor level, blocking opioid receptors and precipitating the withdrawal syndrome, while controlling it. This is achieved through use of medications, including anesthetic agents that allow withdrawal to occur, while the patient is unconscious. Rapid detox should only be performed in an intensive care unit of an acute hospital. Procedures that require anesthesia and intubation should be performed in a safe and well-monitored environment. Answered by Cassidy Kenley 4 months ago.

Two weeks of methadone is an established opiate physical dependancy. Brace yourself. Methadone has HORRIBLE withdrawal symptoms if you stop cold, just as bad as heroin (not an exaggeration). Your dose is fairly low, but get off it before it gets worse. Wean like you are supposed to, and keep weaning STRICTLY no matter how bad it hurts. Don't stop cold if you have kids to take care of.. you won't be able to function properly for a little while. Wean and take it little by little. Going cold, you could be feeling bad for weeks, the peak being probably the 3rd or 4th day. Take Ibuprofren for the muscle aches, soak in a hot tub with epsom salt, use heating pads.. your muscles will be very sore as your body releases it. Your stomach will be upset, so make sure you're close to a toilet. Drink lots and lots of water to help flush your body, and force yourself to move around. YOU CAN DO THIS!! Answered by Brady Pecanty 4 months ago.

well, no offense to the 1st answer but, being a child of foster care and currently on Methadone I would like to tell you of my plight. For 2 years I was sucessfully on Methadone to help me with sickness from pain meds. It took 120mg a day to sustain me and I was like you. Looking for an alternitive I was refered to a doctor who swore Suboxone was the answer for me. Now I recomend you look it up and ask about it thoroughly it seems to be a godsend to some. Unfortunatly, that wasn't my case and after almost a year of my life falling apart I am back on 110mgs and going to the clinic every day again. It is said that withdrawl from Suboxone is less than Methadone but, after 6 weeks of cold turkey I was just as sick as the first week and only people who have been in withdrawl know the meaning of "sick". However my friend who I refered to the clinic has went from 120mg's to 40 in the time I have wasted w/ Suboxone and is almost in your position as far as quiting and they say that Suboxone is more sucessful for people on lower doses. I know it's kinda trading one for another but, the side effect are mild to none compared to Methadone. As I said s/w you doctor or one he referes and best of luck. If you have more questions please feel free to ask me. It is a tough fight but, not impossible. Take care and you are in my prayers(and I am not that religous) you have two very good reasons to do whatever it takes and don't forget it. Answered by Ashanti Olenick 4 months ago.

I'm. 22. Been a junkie for 7 years. I started methadone on Dec.24.14 I went up to 110mg. I started to go down four months ago. 5Mgs every 3days. It's been easy going. No bad dts. I'm at 2mg and have four days left. Answered by Ginger Cavazos 4 months ago.

there is a HUGE likelihood that it would. Methadone is detrimental ample on its own, allow on my own blending it with something. Like you stated, methadone factors your respitory process to slpw down, and so does alcohol. You might fall asleep, and now not wake again up. watch out Answered by Meghann Fobes 4 months ago.

k...if you go off cold turkey you will have a very very very very very dangerous effect since you're dealing with methadone. why are you on a pain killer? i'd call the doctor if i were you, you should be on something less dangerous.. Answered by Mattie Manigold 4 months ago.

maybe someone in your family can take the children for a while because you need some serious help. You do no good to expose your children to this. If you are suffering they will know. Maybe you can have them go into foster care so you can get inpatient treatment. It would be very hard but would show you love your kids enough to do the right thing. Answered by Loriann Mcgaughey 4 months ago.

2 weeks tops to rid of any and all withdrawls I'm sure and to help deal with them would be sleep,Take nytol or somethhing. Answered by Chin Ruzycki 4 months ago.


Why do drug names contain "hydrochloride"?
I tried a simple Google search, but didn't find the results I was looking for.Why do drug names contain the name "hydrochloride"? For example, paroxetine hydrochloride or hydrochloride salt of procaine. I'm THINKING it has to do with the polarity of amines and salts and the solubility in... Asked by Brittny Oberfell 4 months ago.

I tried a simple Google search, but didn't find the results I was looking for. Why do drug names contain the name "hydrochloride"? For example, paroxetine hydrochloride or hydrochloride salt of procaine. I'm THINKING it has to do with the polarity of amines and salts and the solubility in water. Thanks in advance! Answered by Anibal Hovard 4 months ago.

Many drugs are prepared as hydrochloride salts because they're in an inappropriate form as a freebase, this could be because of their strength or texture this way or in the case of ketamine and some others it's so strong an alkali that it's almost caustic. Examples: Cocaine Hydrochloride Ketamine Hydrochloride Methadone Hydrochloride Brupenorphine Hydrochloride Answered by Simone Maggiore 4 months ago.


Do I have to dissolve my 40MG Tablets of Methadone? Why am I not supposed to chew and/or swallow them?
I have been on methadone maintenance for about 3 years now & I just gained something called Step 30 which means that I don't have to go in to the clinic every day anymore. Instead, I come in once a month to pick up a months worth of pills. When I went in to the clinic I was getting liquid methadone, but now I... Asked by Bertha Whites 4 months ago.

I have been on methadone maintenance for about 3 years now & I just gained something called Step 30 which means that I don't have to go in to the clinic every day anymore. Instead, I come in once a month to pick up a months worth of pills. When I went in to the clinic I was getting liquid methadone, but now I have the Methadose 40mg Methadone Hydrochloride Tablets For Oral Suspension USP. On a different label they are also called Methadone HCL 40mg Diskettes. I'm told that I am not supposed to chew and/or swallow them before I dissolve them in water. Unfortunetly, they taste horrible and even mixing them in OJ is nasty. My question is, why can't I break them up & swallow them, & if I did what would be the worst thing that could happen? If I do absolutely have to dissolve them first, do you have any advice on a less painful way to administer them? Thanks! Answered by Carline Pullam 4 months ago.

I have had the liquid methadone & the wafers. I also had trouble drinking the dissolved solution. I experimented taking them in different ways & found that if you break them up into 1/4 pieces or 1/8 pieces & swallow them that you won't notice a difference between that & dissolving them. Answered by Kent Besley 4 months ago.

Methadone Wafers Answered by Lakendra Reial 4 months ago.

Best Way To Take Methadone Answered by Lisha Hieb 4 months ago.

A tablet designed to be swallowed, rather than chewed is usually meant to be dissolved in the stomach and release the contents in a steady manner. Sometimes, it's because the medicine itself is very bitter. In the first case, the effect of chewing and therefore circumventing the intended flow of medicine to the patient's system is that there'll be spikes and valleys of when the medicine is being absorbed into the system. The second case's problem is that the patient dislikes the medicine to the point of not taking the dosage. Either way, the medicinal effect is not attained. Answered by Britney Yaple 4 months ago.

They say to dissolve them so you don't CHOKE on them. Breaking the pill up does NOT make it immediate release...IT IS IMMEDIATE RELEASE ANYWAY!!! there is no coating or time release stuff in methadone.. Breaking the 40mg methadone wafer into pieces will have the same effect as if you eat it whole...DONT CHOKE ON IT LOL Answered by Deetta Castillejo 4 months ago.

Same, I've heard of many people swallowing them, and unless you notice a difference ( I don't either ^anonymous) then just break them up and swallow it. They dissolve FAST so don't take too many at one time. I realize question is 5 years old but this is for future readers Answered by Princess Vile 4 months ago.

Reason why they say not to swallow them whole is because it will act like a Immediate release, Which is not the purpose of the diskettes. Its supposed to be mixed with a solution becuse it was made to get mixed with the solution and when you drink it, the acids in your stomach will dissolve the solution slowly,. acting more like a sustained release. since your doing a methadone maintenance, i would recommend you just dissolving in water. Answered by Lorene Yarnall 4 months ago.

i swallow them like any other pill never had a problem what state are you in Answered by Madaline Stater 4 months ago.


Norco Now. Doc wants me on MS Contin or OxyContin or Methadone, or Opana. I am not sure if this is a good idea?
I have Ankylosing Spondylitis with chronic joint pain, spine paine, Etc....I was on Norco 4 x Daily for over a year, then my Rhuematoligist made up this policy that he could only dispense 90 a mth. So he referred me to a pain clinic and the first appt. the paind cotor wants to put me on Anything stronger than... Asked by Pricilla Abilez 4 months ago.

My pain doctor wants to put me on any one of ALL of the above. I am on Norco 10/325 as of now for a over a year now. I like the Norco because I don't lay around all day and sleep. I actually feel good and the doctor wants me to get on those stronger drugs where I would have to worry about my breathing and I am not for sure if I want to take that route. What do you think is best if I did have to go to the next level? Answered by Dong Bongiardina 4 months ago.

I have Ankylosing Spondylitis with chronic joint pain, spine paine, Etc.... I was on Norco 4 x Daily for over a year, then my Rhuematoligist made up this policy that he could only dispense 90 a mth. So he referred me to a pain clinic and the first appt. the paind cotor wants to put me on Anything stronger than Norco. Why? is my question. When I told him that 4 norcos a day are fine. They are working. Why stop something that is not working. He says that they will eventually not work on me. But haven't yet. Answered by Artie Merksamer 4 months ago.

First of all what is your medical problem? MS Contin contains Morphine OxyContin contains Oxycodone hydrochloride Methadone Question to ask here is why is he increasing strength of medication. It looks like that your have developed tolerance (high dose needed to achieve same effect) or your pain is chronic. Morphine is the best choice. However you should stick with Norco. Morphine has lots of sides effects. Others are more dangerous than Morphine! Answered by Alton Byker 4 months ago.

Opana Vs Methadone Answered by Emelina Portie 4 months ago.

There's no reason you should feel you can't mention it to your doctor. It's a perfectly valid question. It sounds like you've developed some tolerence to the MS Contin, which is natural so possibly your dose just needs to be adjusted. I've been taking MS Contin and just recently my dose was bumped up a bit because it wasn't helping as much. Answered by Brett Shinall 4 months ago.

No Methadone. Let me say that first. Methadone can be good for pain control (especially neuropathic pain) but it has higher risks of death than any opiate (even heroin). So that would be a last option. The pain management doc is correct and at one time or another you will become tollorent. MS Contin and OxyContin are great drugs for pain and are usually not as sedating as Hydrocodone (but everyone is different). And I would hope you would not be precribed a dose that could easily cause repritory distress. A starting dose of either MS or Oxy is about 30-40mg for equivalent pain control. So a dose arround there is fine. 80mg of OxyContin would be over kill. So if the doctor will not let you use the Norco (and I take the exact dose you take, I know it works well) then I would pick MS Contin or OxyContin and at least try it. But break through pain meds are also good in addition. I have also taken MS Contin and OxyContin. What I did when my pain was the most extreme was to take MS and Norco or Oxy-IR (Oxycodone instant release). That way I was using a long acting drug (The MS) and I had the option of fast acting drugs (Norco or Oxy-IR) for break through pain or the days when you just want to scream because you are in so much pain. But that is just me. I will say it does sound very odd. Best of luck If you have other question feel free to contact me. I have different pain but I know how difficult it can be. Answered by Kennith Baise 4 months ago.

You need help. I cant even believe that you have asked this question Im sorry Im so Blunt. I am an alcoholic I understand pain in a different way. You obviously said something that made your doc change his decision regarding your pain meds.My mother is a nurse. you want real answers? [email protected] Answered by Merrill Seace 4 months ago.

I use Norco and Avinza for pain. My rx is 3 Norco 3-4 times a day as needed for breakthru pain. 12 is my daily limit because of the tylenol. Norco, Vicodin, etc are short acting drugs so you get peaks and valleys in regards to the pain relief. When you use a long acting medication like Avinza, Kadian, Oxycontin you have a steady level in your bloodstream and your pain is better controlled. I was given Avinza after using Norco for a year. I was taking 12 tabs faithfully to try and cover the pain. Now I rarely need it because the Avinza does such a great job. The body adapts quickly so any side effects like drowsiness go away in a few days. If you're only taking 4 Norco a day, you'll be put on a very small dose of whatever opioid/opiate the doctor wants to use. Depression in breathing is not something I'd worry about. Simple distinction between dependence and addiction. Addiction is a set of psychological behaviors that focus on obtaining a drug for non-pain purposes focusing on analgesia here). So if you have ever called in a script to a pharmacy posing as office staff, if you have ever bought the drug on the street, if you have ever taken the drug for purposes other than for pain (to get numb, to "relax" when you aren't in pain, etc.) then you are engaging in addictive behaviors. If you are taking the pain medication EVERYTIME because you are in pain or you are attempting to keep your blood levels up to keep pain down to a minimum BUT if you suddenly stopped the med you suffer through opiate withdrawal, aka "jonesing", then you are dependent on the medication. You are NOT an addict. There are blood pressure meds, e.g., clonidine, that you become dependent on and can have nasty rebound hypertension if you suddenly stopped. Are you then a clonidine addict? Answered by Kiley Hepner 4 months ago.


If your on methadone and switch to suboxin too early do you go into withdrawls?
My husband was at 64 milligrams of methadone quit cold turkey for 40 hrs, his doctor switched him to 8 milligrams of suboxin and now he is on the floor in withdrawels....Is this normal??? Asked by Cliff Holgate 4 months ago.

It's not that he was switched too early, he was started too late. Contact the prescriber immediately. He'll probably increase the dose for a short period of time. Also make sure he's dissolving the tablet under the tongue. If he's swallowing the pill, it's inactivated by the liver in what's called the "first-pass effect." Rick the Pharmacist (work in a drug treatment center part-time) Addendum Nalxone when taken orally has absolutely no pharmacological activity. It is only active if injected. It does not survive the liver's "first pass effect." I've seen patient need as much as 24mg the first few days. Subutex would be an option, too. Naloxone when administered orally at 0.5 mg has no pharmacologic activity. Naloxone hydrochloride administered parenterally at the same dose is an effective antagonist to pentazocine and a proof antagonist to narcotic analgesics. Physiologic and subjective effects following acute sublingual administration of SUBOXONE and SUBUTEX tablets were similar at equivalent dose levels of buprenorphine. Naloxone, in the SUBOXONE formulation, had no clinically significant effect when administered by the sublingual route, although blood levels of the drug were measurable. SUBOXONE, when administered sublingually even to an opioid-dependent population, was recognized as an opioid agonist, whereas when administered intramuscularly, combinations of buprenorphine with naloxone produced opioid antagonist actions similar to naloxone. In methadone-maintained patients and heroin-dependent subjects, intravenous administration of buprenorphine/naloxone combinations precipitated opioid withdrawal and was perceived as unpleasant and dysphoric. In morphine-stabilized subjects, intravenously administered combinations of buprenorphine with naloxone produced opioid antagonist and withdrawal effects that were ratio-dependent; the most intense withdrawal effects were produced by 2:1 and 4:1 ratios, less intense by an 8:1 ratio. SUBOXONE tablets contain buprenorphine with naloxone at a ratio of 4:1. Answered by Lelah Boltz 4 months ago.

There is no such thing as normal when it comes to opiates. Every single person in this world has a different brain and receptor topology. Some people can be in withdrawal for 12 hours, feel only slight discomfort, and have no problems at all switching to Suboxone. Others wait over 40 hours, feel like absolute crap and wait until major withdrawal (or so they think), yet when they switch to Suboxone, they go into worse withdrawal. The best advice, no matter how many answers you may get or how many sites you read, is to wait as long as possible. Some people who take methadone are told that they can't switch to Suboxone until greater than a week! Methadone is a long lasting opiate and there are literally dozens of factors which will influence how fast it is removed from receptors in the brain, the bloodstream, and the liver, such as metabolism, other drugs taken, etc. In addition, make sure he took it correctly. Suboxone contains Naloxone, which is used to deter illegal use and if taken incorrectly (not under the tongue), it could induce severe withdrawal. Also, there have been many circumstances where people think they are ready and yet still go into withdrawal, as I stated above. There are even people who CAN absorb Naloxone through the sublinqual veins, even though it is only supposed to be minimal absorption. So my final answer would be that it may not be normal, but does that matter? The important thing is that he is probably feeling like total crap and you need to do something. Ask the doctor to maybe try Subutex, which does not contain Naloxone. That way, if your husband for some reason does absorb Naloxone by some weird avenue, this would not be an issue. Also, I do have one question out of curiosity. Why did your husband decide to switch to Suboxone? Was the methadone not working anymore? Does he not like going to a clinic every day? You could increase the Suboxone, but like I said, if he is having a reaction to Naloxone, then that could be even worse! If you would like to email me personally, feel free to do so and perhaps we could talk in much more detail as I would love to help him. And one last thing - if he is currently feeling terrible, tell him to take some quick acting opiates, like maybe a couple of Percocets or something. I am NOT a doctor so please take that advice with some hesitation. However, because the Suboxone is now occupying the receptors, you need to knock it out of there in order for him to feel better. Suboxone has a long half-life so it takes a while naturally (about 8 hours or so if he only took 8mg as you describe). The absolute best choice, as I hinted (I think), is to go right back to methadone, as you know he can handle that and it will fix him for the time being, which is the MOST important thing. Then after a couple of weeks, maybe he can go for it again, but this time, wait much longer than 40 hours. Unfortunately, your husband has learned the hard way that his brain is not "normal" as you say, and maybe he is going to need a lot longer than 40 hours to get all the methadone out of his bloodstream, liver, brain, etc. It lives in a lot of places, including being stored in the liver, so sometimes it takes a lot longer than 40 hours. One of the worst issues with Suboxone is exactly what happened to your husband. Since every person is different, there is no ONE answer to how long a person should wait. It is a trial and error kind of thing, and unfortunately, as you have witnessed, NOT one of the more pleasant trial and error situations. Answered by Aida Goll 4 months ago.


Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
006383/002 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE POWDER/FOR RX COMPOUNDING 50GM per BOT
006383/003 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE POWDER/FOR RX COMPOUNDING 100GM per BOT
006383/004 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE POWDER/FOR RX COMPOUNDING 500GM per BOT
017058/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET, FOR SUSPENSION/ORAL 40MG
021624/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE INJECTABLE/INJECTION 10MG per ML
040088/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE CONCENTRATE/ORAL 10MG per ML
040180/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE CONCENTRATE/ORAL 10MG per ML
040241/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 5MG
040241/002 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 10MG
040517/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 5MG
040517/002 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 10MG
074081/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 40MG
075082/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET, FOR SUSPENSION/ORAL 40MG
077142/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET, FOR SUSPENSION/ORAL 40MG
087393/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE SOLUTION/ORAL 5MG per 5ML
087997/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE SOLUTION/ORAL 10MG per 5ML
088108/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 5MG
088109/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 10MG
090065/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 5MG
090065/002 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 10MG
090635/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 10MG
090707/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE SOLUTION/ORAL 5MG per 5ML
090707/002 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE SOLUTION/ORAL 10MG per 5ML
203502/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 5MG
203502/002 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 10MG

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
006134/002 DOLOPHINE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 5MG
006134/004 DOLOPHINE HYDROCHLORIDE METHADONE HYDROCHLORIDE SYRUP/ORAL 10MG per 30ML
006134/010 DOLOPHINE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 10MG
006383/002 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE POWDER/FOR RX COMPOUNDING 50GM per BOT
006383/003 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE POWDER/FOR RX COMPOUNDING 100GM per BOT
006383/004 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE POWDER/FOR RX COMPOUNDING 500GM per BOT
017058/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET, FOR SUSPENSION/ORAL 40MG
017108/001 WESTADONE METHADONE HYDROCHLORIDE TABLET, DISPERSIBLE/ORAL 2.5MG
017108/002 WESTADONE METHADONE HYDROCHLORIDE TABLET, EFFERVESCENT/ORAL 5MG
017108/003 WESTADONE METHADONE HYDROCHLORIDE TABLET, EFFERVESCENT/ORAL 10MG
017108/004 WESTADONE METHADONE HYDROCHLORIDE TABLET, EFFERVESCENT/ORAL 40MG
017116/002 METHADOSE METHADONE HYDROCHLORIDE CONCENTRATE/ORAL 10MG per ML
021624/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE INJECTABLE/INJECTION 10MG per ML
040050/001 METHADOSE METHADONE HYDROCHLORIDE TABLET/ORAL 5MG
040050/002 METHADOSE METHADONE HYDROCHLORIDE TABLET/ORAL 10MG
040088/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE CONCENTRATE/ORAL 10MG per ML
040180/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE CONCENTRATE/ORAL 10MG per ML
040241/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 5MG
040241/002 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 10MG
040517/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 5MG
040517/002 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 10MG
074081/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 40MG
074184/001 METHADOSE METHADONE HYDROCHLORIDE TABLET, FOR SUSPENSION/ORAL 40MG
075082/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET, FOR SUSPENSION/ORAL 40MG
077142/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET, FOR SUSPENSION/ORAL 40MG
087393/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE SOLUTION/ORAL 5MG per 5ML
087997/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE SOLUTION/ORAL 10MG per 5ML
088108/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 5MG
088109/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 10MG
089897/001 METHADONE HYDROCHLORIDE INTENSOL METHADONE HYDROCHLORIDE CONCENTRATE/ORAL 10MG per ML
090065/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 5MG
090065/002 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 10MG
090635/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 10MG
090707/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE SOLUTION/ORAL 5MG per 5ML
090707/002 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE SOLUTION/ORAL 10MG per 5ML
203502/001 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 5MG
203502/002 METHADONE HYDROCHLORIDE METHADONE HYDROCHLORIDE TABLET/ORAL 10MG

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