Application Information

This drug has been submitted to the FDA under the reference 020134/001.

Names and composition

"METASTRON" is the commercial name of a drug composed of STRONTIUM CHLORIDE SR-89.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
020134/001 METASTRON STRONTIUM CHLORIDE SR-89 INJECTABLE/INJECTION 1mCi per ML

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
020134/001 METASTRON STRONTIUM CHLORIDE SR-89 INJECTABLE/INJECTION 1mCi per ML
075941/001 STRONTIUM CHLORIDE SR-89 STRONTIUM CHLORIDE SR-89 INJECTABLE/INJECTION 1mCi per ML

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Answered questions

How and where is Strontium 89 produced for nuclear medicine?
Thanks guys Cheers Asked by Tommie Mosman 1 year ago.

Strontium-89 for "Metastron" (the Merck/Amersham brand) is made in nuclear reactors, with the help of the US government's nuclear chemistry boffins at Oak Ridge, Tennessee, who said in a 1994 newsletter: "The strontium-89 in Metastron is produced in five European reactors by neutron irradiation of targets enriched in strontium-88 by ORNL. The source of the strontium-88 is a set of calutrons at the Oak Ridge Y-12 Plant operated by ORNL's Isotope Enrichment Group headed by Joe Tracy. The calutrons, which separate isotopes electromagnetically, were originally used to produce enriched uranium for the Manhattan Project during World War II. " Strontium-88 is naturally occurring, but needs to be isolated from other naturally occurring isotopes by enrichment. Answered by Margo Brafman 1 year ago.


What alkaline earth metal is used for cancer treatment?
Because of it s radioactivity? Asked by Katie Walen 1 year ago.

Strontium here are its isotopes used for cancer treatment 89Sr is the active ingredient in Metastron, a radiopharmaceutical used for bone pain secondary to metastatic prostate cancer. The strontium acts like calcium and is preferentially incorporated into bone at sites of increased osteogenesis. This localization focuses the radiation exposure on the cancerous lesion. 90Sr is also used in cancer therapy. Its beta emission and long half-life is ideal for superficial radiotherapy. The human body absorbs strontium as if it were calcium. Due to the elements being sufficiently similar chemically, the stable forms of strontium do not pose a significant health threat, but the radioactive 90Sr can lead to various bone disorders and diseases, including bone cancer. The strontium unit is used in measuring radioactivity from absorbed 90Sr. An innovative drug made by combining strontium with ranelic acid has aided in bone growth, boosted bone density and lessened vertebral, peripheral and hip fractures.[4] [5] Women receiving the drug showed a 12.7% increase in bone density. Women receiving a placebo had a 1.6% decrease. Half the increase in bone density (measured by x-ray densitometry) is attributed to the higher atomic weight of Sr compared with calcium, whereas the other half a true increase in bone mass. It means that strontium ranelate creates new, stronger bone. Strontium ranelate (marketed under the trade names Protelos, Osseor, Protos, Bivalos, Protaxos, Ossum) is registered for treatment of osteoporosis in many countries all over the world. Strontium ranelate has been shown to strengthen bones, according presentations given the IOF World Congress on Osteoporosis, in June of 2006. It also reduced bone resorbtion. Strontium ranelate is registered as a prescription drug in Europe and many countries worldwide. It needs to be prescribed by a doctor, delivered by a pharmacist and requires a strict medical supervision. Currently, (early 2007) it is not available in Canada or the United States. Several other salts of strontium such as strontium citrate or strontium carbonate are often presented as natural therapies and sold at a dose that is several hundred times higher than the usual strontium intake. Despite the lack of strontium deficit referenced in the medical literature and the lack of information about possible toxicity of strontium supplementation, such compounds can still be sold in the United States under the Dietary Supplements Health and Education Act of 1994. However, their long-term safety and efficacy have never been evaluated on humans using large-scale medical trials. Such compounds should not be administered to humans before further studies are conducted. Answered by Romaine Fidler 1 year ago.

radium (Ra), and wen first discovered, compounds of the metal were used on watch dials for self-luminescence and in early cancer therapy. radium is a source of radioactive rays traditionally used in cancer treatment, though other radioactive isotopes are now more commonly used. A radioactive isotope of strontium, strontium-90, is a component of nuclear fallout. (trust me this is the right answer search it on google or just click the link, hate me 4ever if im wrong, but im pretty sure im write) hope this helps :) Answered by Fredricka Tassie 1 year ago.

battery operated microwaves Answered by Beryl Outman 1 year ago.


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