Application Information

This drug has been submitted to the FDA under the reference 006008/001.

Names and composition

"MESANTOIN" is the commercial name of a drug composed of MEPHENYTOIN.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
006008/001 MESANTOIN MEPHENYTOIN TABLET/ORAL 100MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
006008/001 MESANTOIN MEPHENYTOIN TABLET/ORAL 100MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**

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Answered questions

Please help ten points for the best answer...what are the 38 drugs that can cause drug induced lupus?
Asked by Magda Casadei 1 year ago.

Please note that this list is only partial - there now appear to be at least 70 meds which can cause DILE or DIL, drug-induced Lupus Erythematosis Atenolol (Tenormin) Captopril (Capoten) Carbamazepine Chlorpromazine HCl (Thorazine) Clonidine HCl (Catapres) Danazol (Danocrine) Diclofenac (Cataflam, Voltaren) Disopyramide (Norpace) Ethosuximide (Zarontin) Gold compounds Griseofulvin Hydralazine HCl (Apresoline) Ibuprofen Interferon alfa Isoniazid (Laniazid, Nydrazid) Labetalol HCl (Normodyne, Trandate) Leuprolide acetate (Lupron) Levodopa (Dopar, Larodopa) Lithium carbonate Lovastatin (Mevacor) Mephenytoin (Mesantoin) Methyldopa (Aldomet) Methysergide maleate (Sansert) Minoxidil (Loniten, Rogaine) Nalidixic acid (NegGram) Nitrofurantoin (Furadantin, Macrobid, Macrodantin) Oral contraceptives Penicillamine (Cuprimine, Depen) Penicillin Phenelzine sulfate (Nardil) Phenytoin sodium (Dilantin) Prazosin (Minipress) Primidone (Mysoline) Procainamide HCl (Procan, Pronestyl) Promethazine HCl (Anergan, Phenergan) Propylthiouracil Psoralen Quinidine Spironolactone (Aldactone) Streptomycin sulfate Sulindac (Clinoril) Sulfasalazine (Azulfidine) Tetracycline Thioridazine HCl (Mellaril) Timolol maleate (Betimol, Timoptic) Tolazamide (Tolinase) Tolmetin sodium (Tolectin) Trimethadione (Tridione) One thing I happened to notice is that several meds used to treat Parkinson's disease are in this list. And the problem is that although Lupus is not curable, in DILE, the symptoms are reversible once the medications are discontinued. Of course in PD, that might not be possible, The most common problems are caused by only a handful of the above. Answered by Rocio Barios 1 year ago.


Neutropenia & Raynauds disease?
I have been diagnosed with Raynaud’s disease and have had it for about 4 years (get it every winter). I get really bad chilblains from it. I went to the doctor to show him and he sent me off for a blood test. Anyway he rang me today and said I will need to get another blood test in 3 wks as I have moderate... Asked by Mariana Nevis 1 year ago.

I have been diagnosed with Raynaud’s disease and have had it for about 4 years (get it every winter). I get really bad chilblains from it. I went to the doctor to show him and he sent me off for a blood test. Anyway he rang me today and said I will need to get another blood test in 3 wks as I have moderate Neutropenia. What is this? I don’t really have any of its symptoms, all I have is chilblains. I have looked it up and it said it could be related to cancer, does that mean I have cancer? I’m really worried, please help! Thanks Answered by Edwina Rhyner 1 year ago.

Don't panic! Basically it's a shortage of a certain type of white blood cell. This can be from an infection or many other things it's more a symptom of something wrong more that the thing itself. Why don't you call his nurse tomorrow and have the doctor talk to you about it. Maybe if he doesn't you need another doctor. ok I'm going to add this on because the article i read says it can be drug induced or a shortage of some vitamins.... Infections are the most common form of acquired neutropenia. Nutritional deficiencies include vitamin B-12, folate, and copper deficiency. Acquired neutropenia caused by drugs and chemicals, excluding cytotoxic chemotherapy The highest-risk categories are antithyroid medications, macrolides, and procainamides. Antimicrobials include penicillin, cephalosporins, vancomycin, chloramphenicol, gentamicin, clindamycin, doxycycline, flucytosine, nitrofurantoin, novobiocin, minocycline, griseofulvin, lincomycin, metronidazole, rifampin, isoniazid, streptomycin, thiacetazone, mebendazole, pyrimethamine, levamisole, ristocetin, sulfonamides, chloroquine, hydroxychloroquine, quinacrine, ethambutol, dapsone, ciprofloxacin, trimethoprim, imipenem/cilastatin, zidovudine, fludarabine, acyclovir, and terbinafine. Analgesics and anti-inflammatory agents include aminopyrine, dipyrone, phenylbutazone, indomethacin, ibuprofen, acetylsalicylic acid, diflunisal, sulindac, tolmetin, benoxaprofen, barbiturates, mesalazine, and quinine. Antipsychotics, antidepressants, and neuropharmacologic agents include phenothiazines (chlorpromazine, methylpromazine, mepazine, promazine, thioridazine, prochlorperazine, trifluoperazine, trimeprazine), clozapine, risperidone, imipramine, desipramine, diazepam, chlordiazepoxide, amoxapine, meprobamate, thiothixene, and haloperidol. Anticonvulsants include valproic acid, phenytoin, trimethadione, Mesantoin, ethosuximide, and carbamazepine. Antithyroid drugs include thiouracil, propylthiouracil, methimazole, carbimazole, potassium perchlorate, and thiocyanate. Cardiovascular drugs include procainamide, captopril, aprindine, propranolol, hydralazine, methyldopa, quinidine, diazoxide, nifedipine, propafenone, ticlopidine, and vesnarinone. Antihistamines include cimetidine, ranitidine, tripelennamine (Pyribenzamine), methaphenilene, thenalidine, brompheniramine, and mianserin. Miscellaneous drugs include allopurinol, colchicine, aminoglutethimide, famotidine, bezafibrate, flutamide, tamoxifen, penicillamine, retinoic acid, metoclopramide, phenindione, dinitrophenol, ethacrynic acid, dichlorodiphenyltrichloroethane (DDT), cinchophen, antimony, pyrithyldione, rauwolfia, ethanol, chlorpropamide, tolbutamide, thiazides, spironolactone, methazolamide, acetazolamide, IVIG, and levodopa. Heavy metals include gold, arsenic, and mercury. Again don't freak yourself out just talk to the doc! Answered by Dee Carlington 1 year ago.


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