Application Information

This drug has been submitted to the FDA under the reference 019732/001.

Names and composition

"LUPRON DEPOT" is the commercial name of a drug composed of LEUPROLIDE ACETATE.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
019732/001 LUPRON DEPOT LEUPROLIDE ACETATE INJECTABLE/INJECTION 7.5MG per VIAL
020011/001 LUPRON DEPOT LEUPROLIDE ACETATE INJECTABLE/INJECTION 3.75MG per VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
020011/002 LUPRON DEPOT LEUPROLIDE ACETATE INJECTABLE/INJECTION 3.75MG
020517/001 LUPRON DEPOT LEUPROLIDE ACETATE INJECTABLE/INJECTION 22.5MG per VIAL
020517/002 LUPRON DEPOT LEUPROLIDE ACETATE INJECTABLE/INJECTION 30MG per VIAL
020517/003 LUPRON DEPOT LEUPROLIDE ACETATE INJECTABLE/INJECTION 45MG per VIAL
020708/001 LUPRON DEPOT LEUPROLIDE ACETATE INJECTABLE/INJECTION 11.25MG per VIAL

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
019010/001 LUPRON LEUPROLIDE ACETATE INJECTABLE/INJECTION 1MG per 0.2ML
019732/001 LUPRON DEPOT LEUPROLIDE ACETATE INJECTABLE/INJECTION 7.5MG per VIAL
019943/002 LUPRON LEUPROLIDE ACETATE INJECTABLE/ INJECTION 3.75MG
020011/001 LUPRON DEPOT LEUPROLIDE ACETATE INJECTABLE/INJECTION 3.75MG per VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
020011/002 LUPRON DEPOT LEUPROLIDE ACETATE INJECTABLE/INJECTION 3.75MG
020263/002 LUPRON DEPOT-PED LEUPROLIDE ACETATE INJECTABLE/INJECTION 7.5MG per VIAL
020263/003 LUPRON DEPOT-PED LEUPROLIDE ACETATE INJECTABLE/INJECTION 3.75MG per VIAL,7.5MG per VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
020263/004 LUPRON DEPOT-PED LEUPROLIDE ACETATE INJECTABLE/INJECTION 7.5MG per VIAL,7.5MG per VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
020263/005 LUPRON DEPOT-PED LEUPROLIDE ACETATE INJECTABLE/INJECTION 11.25MG per VIAL
020263/006 LUPRON DEPOT-PED LEUPROLIDE ACETATE INJECTABLE/INJECTION 15MG per VIAL
020263/007 LUPRON DEPOT-PED LEUPROLIDE ACETATE INJECTABLE/INJECTION 11.25MG per VIAL
020263/008 LUPRON DEPOT-PED LEUPROLIDE ACETATE INJECTABLE/INJECTION 30MG per VIAL
020517/001 LUPRON DEPOT LEUPROLIDE ACETATE INJECTABLE/INJECTION 22.5MG per VIAL
020517/002 LUPRON DEPOT LEUPROLIDE ACETATE INJECTABLE/INJECTION 30MG per VIAL
020517/003 LUPRON DEPOT LEUPROLIDE ACETATE INJECTABLE/INJECTION 45MG per VIAL
020708/001 LUPRON DEPOT LEUPROLIDE ACETATE INJECTABLE/INJECTION 11.25MG per VIAL
021088/001 VIADUR LEUPROLIDE ACETATE IMPLANT/IMPLANTATION EQ 65MG BASE
021343/001 ELIGARD LEUPROLIDE ACETATE INJECTABLE/SUBCUTANEOUS 7.5MG per VIAL
021379/001 ELIGARD LEUPROLIDE ACETATE INJECTABLE/SUBCUTANEOUS 22.5MG per VIAL
021488/001 ELIGARD LEUPROLIDE ACETATE INJECTABLE/SUBCUTANEOUS 30MG per VIAL
021731/001 ELIGARD LEUPROLIDE ACETATE INJECTABLE/SUBCUTANEOUS 45MG per VIAL
074728/001 LEUPROLIDE ACETATE LEUPROLIDE ACETATE INJECTABLE/INJECTION 1MG per 0.2ML
075471/001 LEUPROLIDE ACETATE LEUPROLIDE ACETATE INJECTABLE/INJECTION 1MG per 0.2ML
075721/001 LEUPROLIDE ACETATE LEUPROLIDE ACETATE INJECTABLE/INJECTION 1MG per 0.2ML
078885/001 LEUPROLIDE ACETATE LEUPROLIDE ACETATE INJECTABLE/INJECTION 1MG per 0.2ML

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Answered questions

Lupron depot?
complcations with long use?i haveon this for almost 9 years Asked by Lorette Dryden 2 years ago.

I was on it about 13 years ago. I didn't have any problems with it other than it shut down my cycles for those 6 months. You'll be fine. After those, you should consider Seasonale birth control. I've been on that for the last 2 years for my endometriosis. Before that I was on the depo provera shots for 9 years Answered by Zella Wagman 2 years ago.


Has anybody ever taken the lupron depot shot and what were the side effects?
would you recommend taking the injection to cure the endometriosis? Asked by Kevin Obermann 2 years ago.

I had 3 lupron depot before I couldnt stand them anymore. My pain got worse with the shots not better. Then there was the hot flashes and mood swings. I wouldnt recommend the shots but that was just experience it might work for you. Answered by Bud Handshaw 2 years ago.

I tried it for two months and it did absolutely nothing except make me more miserable. A friend of mine had them for six months and she was worse off than me. I remember having hot flashes and night sweats that were far worse than actual menopause. The shot definitely did not cure my endometriosis. I ended up having a total hysterectomy which was far better than those awful shots. Maybe other people have had good results with Lupron but I did not. Good Luck!! Answered by Khadijah Pel 2 years ago.


Lupron depot shot for women?
has anyone heard, or had the lupron depot shot for endometriosis and what were your or there expreince with it? i am about to get the shot and it last for 6 months Asked by Kevin Tant 2 years ago.

Lupron Depot Shot Answered by Myriam Lawerance 2 years ago.

HI, wife had it and it was the worst thing going. she gained a ton of weight and has never lost it. it basiclaly is putting you into menepause chemicaly induced for 6 months since the endo feeds off your estrogen. they put you in menepause so that you do not produce the estrogen, pregancy will do the same thing but you may not want to get prego now. The hormones really messed with her, she had bad diarea and her periods were all messed up for a long time after. And then the endo came right back. Then the doc suggested cutting the nerve to her uterus so at least she would not feel the pain, yeah thats a real cure doc. anyway- she found an applied kinesiaologist who worked with her on the endo and she has been clr ever since. Hope this has helped. email me if you want to chat more. trialtoid@yahoo.com Answered by Carlton Kleparek 2 years ago.

I was on it about 13 years ago. I didn't have any problems with it other than it shut down my cycles for those 6 months. You'll be fine. After those, you should consider Seasonale birth control. I've been on that for the last 2 years for my endometriosis. Before that I was on the depo provera shots for 9 years Answered by Doyle Rahmes 2 years ago.

I had the shot about 4 years ago. I did have some menopausal symptoms. The shot didn't work for me and I ended up having a hysterectomy about 6 months later. Answered by Loura Anable 2 years ago.

the doc wants me on it to, but it puts you threw menopause. you will get all the symptoms a 45 year old lady has. in tying to avoid this the doc but me on bc pills consistently all 30 days. to stop my peroid. Answered by Cornelius Tefera 2 years ago.


What are your experiences with depot lupron?
I have had horrible side effects from the Depot Lupron shot (3-months doasage), now I am not talking about depot provera, this is a stronger shot to treat endometriosis. It has helped with the pain and lessened the growths, but I have bad hot flashes, weight gain, dryness, the list goes on. Anyone have better... Asked by Agustin Joo 2 years ago.

I have had horrible side effects from the Depot Lupron shot (3-months doasage), now I am not talking about depot provera, this is a stronger shot to treat endometriosis. It has helped with the pain and lessened the growths, but I have bad hot flashes, weight gain, dryness, the list goes on. Anyone have better experience with it? Can anyone suggest an alternative treatment?? BCPs don't work, i tried them already. Answered by Sena Kojima 2 years ago.

Stay FAR away from Lupron!!!!! Endo is an estrogen dominance disease. You need to replace the progesterone that your body is missing with a NATURAL PROGESTERONE CREAM! Email me and I can tell you more. This is some very nasty stuff. :( Here is an article I found.... Be Careful of Lupron for Endometriosis, It Could Be the Kiss of Death By Nicholas Regush This particular saga began a decade ago with an injection of a powerful prescription drug called Lupron. Lynne Millican took the shot for endometriosis, a condition in which pieces of the lining of the uterus are found in other parts of the body, especially in the pelvic cavity. Ten years later, Millican believes she is still suffering from the effects of that injection. Her many symptoms have included the development of a noncancerous tumor, breast cysts, cardiac arrythmias, dizziness, swelling and fatigue. Millican is a registered nurse (and paralegal) living in the Boston area who has become deeply involved in a grass-roots movement to force the U.S. Food and Drug Administration (FDA), and Members of Congress to take a close look at Lupron. The FDA first approved Lupron in 1985 for treatment of men with advanced prostate cancer, and then approved it for treatment of endometriosis in 1990 and uterine fibroids in 1995. "There are thousands in the United States who say they have been victimized by this drug," Millican said, emphasizing that symptoms can be severe, such as tremors, seizures and memory loss. "Many women I know say their symptoms didn't stop when they stopped taking the drug." The FDA has received a wide range of reports of serious side-effects, including death, suspected to be associated with the use of Lupron, but the agency, which holds that the drug's benefits outweigh the risks, does not believe there is sufficient proof to blame Lupron. TAP Pharmaceuticals Inc., jointly owned by Abbott Laboratories and Takeda Chemical Industries of Japan, has steadfastly maintained that Lupron is safe. Millican, who feels that the FDA has been very slow on the draw with Lupron, is also frustrated by the lack of response from almost all of the many senators and representatives in Congress to whom she has written. She has even submitted written testimony to various committee hearings - but to no avail. "It seems that no one but the people who suffer from Lupron are interested in looking into this drug," she said. Millican cannot even recall anyone with an MD degree who has voiced strong concern about Lupron. At the very least, she feels Lupron's safety should be an issue because doctors use it for purposes that were never approved by the FDA. While legal under federal law - once approved for an indication, a drug can be used for other purposes - unapproved use often occurs without the benefit of appropriate safety and efficacy studies. One of Millican's main concerns is Lupron's unapproved use in fertility clinics. The drug is essentially used to suppress female hormones which produce a mature egg. This allows fertility doctors to then induce "controlled" stimulation of multiple eggs. "I am concerned that women who undergo these procedures are not being sufficiently informed about Lupron's side-effects," Millican said. There is even much more at stake, according to Millican. On September 5, she provided testimony to congressional committee hearings on stem cell research, pointing out that the use of Lupron in the process of creating embryos may cause "the very diseases that are being claimed as those diseases necessitating embryonic stem cell research for a cure." Millican finds it hard to swallow that the debate over stem cell research has totally ignored Lupron. Redflagsweekly January 25, 2002 Dr. Mercola's Comment: Folks, Lupron is a disaster drug that in no way shape or form treats the cause of the problem. I have seen it absolutely devastate many women's lives. It is one of the few drugs that I actually cringe when patients tell me that they have taken it. It is my experience and belief that this drug causes permanent neurological damage. This drug needs to be avoided at all costs. It is usually used for endometriosis, which is an estrogen dominance problem and is typically treated quite nicely with natural progesterone, a dietary program, and addressing the emotional stresses which cause the adrenal glands to become impaired Since the adrenals is the main biological of estrogen and progesterone, it is important to restore the proper functioning of this gland. One could take adrenal glandulars, or DHEA and pregnenolone, but those tend to be natural band-aids that don't address the reasons the adrenal became impaired. Answered by Ken Mcmickell 2 years ago.

I was one of the first guinea pigs to be prescribed Lupron for severe endometriosis in 1995. I had just undergone a laparoscopy and my ob-gyn insisted I try Lupron, especially, he said, because my husband and I had problems conceiving after one year of trying. The mood swings, migraines, dark, thick hair growth in weird places, hot flashes, and memory loss were only the beginning of the side effects I continue to have, 20 years later. I have not begun menopause, and the only baby that was conceived died in-utero at 16 weeks, and I never conceived again in my whole life. My endometriosis has gotten much worse, although I was diagnosed at stage 4 long ago, so I don t know what they would call the stage I have by now? 4+++? The pain has caused me to have to quit my dream job that I went to college for 7 years to work with children as a child psychologist, only to have my doctor reccomend I file for permanent disability because of the amount of pain medications I was taking to make it through the day, and the amount of memory loss I had incurred from Lupron. I have had hot flashes and mood swings for the past 20 years, so that now I need to take medication for PTSD for being attacked by a child at the school I worked with and my son I adopted when I was getting so sick and weak from the pain. I also have so many adhesions and scar tissue, it is really painful to eat a lot at once, because of the pain caused from intestinal blockages from the endometriosis. Please listen to those who have been on the medication and NOT your doctor!! YOu will also be at high risk for osteoporosis by the time you are 50, even if you are on Lupron for only 6 months. It is truly only a rotton bandaid that doctors get bonuses for and pharmaceutical companies get big bucks from the insurance at $2K per shot!! Don t do it! Answered by Mora Boulay 2 years ago.

I agree stop taking this drug. I have done two years of research because the dr. keeps pushing it on me. I have continued to tell him no. there was one dr. that said if I don't take it he wouldn't treat me. I didn't have him treat me. Dr.'s are trying to find a way out of solving problems, and this is NOT it. I am still struggling with endo and PCS, but I would rather struggle without the side effects. Best of luck to you. I hope you feel better REALLY soon. Answered by Vinita Minney 2 years ago.

I have met women who did Lupron and then when they went off of it had issues with extreme fatigue such as due to Chronic Fatigue Syndrome and even fibromyalgia. I haven't met any as of yet that had issues with insomnia or nausea when coming off the medication though. Answered by Lynelle Fuschetto 2 years ago.


Lupron Depot pros?
In the next few days I will be recieving the Lupron Depot shot (11.25mg). I am 20 years old and have been going through the painful effects of endometrosis for several years.I have read over alot of reviews from this shot and i'm seeing alot of negitive side effects. I get sick really easy so I'm afriad... Asked by Alita Koury 2 years ago.

In the next few days I will be recieving the Lupron Depot shot (11.25mg). I am 20 years old and have been going through the painful effects of endometrosis for several years.I have read over alot of reviews from this shot and i'm seeing alot of negitive side effects. I get sick really easy so I'm afriad that my body will take this shot badly. I had a laproscopy in November of 2006 when I was finally diagnosed with the endo and where they burned out most of it. The next period I had was extreme pain as usual. The only pro that I see in getting this shot is the fact that I will be pain free for 6 months in the period department. I was wondering if there was anymore pros that anyone has experienced fromt his shot. Answered by Mardell Phlieger 2 years ago.

No period for six months is about the only pro. I was in the same situation you are. I was diagnosed with endometriosis, and had been through three different pills, a laproscotomy/ DNC, then finally lupron. To be honest, I still experienced some pain while on the shot. The first month the pain was pretty much the same, because of the time it takes for the medicine to work through the body. After that, I didn't have the sharp stabbing pains, but just mild discomfort every once in a while. Expect when you get your shot for you muscles to tighten around the area that the shot was given. (Usually in the behind alternating cheeks each month.) I really didn't feel sick when I got my shot. However, once the medicine was in my body I had pretty much all the side effects of menopause. (After all, that is what you are putting your body through.) Things I experienced where; hot flashes, breast tenderness, dryness in the cervix, decrease in the sex drive, night sweats, and mood swings. Also, my first pap after the lupron course came back abnormal. I am not trying to get you to not have the course done, because it can be beneficial. However, there are many side effects and problems that can come with it. Answered by Dorothy Finklestein 2 years ago.


Endometriosis and Lupron Depot?
P.S I really have had Endo symptoms since the onset of menses at age 10. I began taking the pill at 13 until I was 19, then became pregnant with my son. I'm now 34. The pill lessened my symptoms, but was still told it was in my head.I DID exercises, relaxation techniques, the WHOLE gammet. I always... Asked by Wayne Mighty 2 years ago.

I have been taking Lupron Depot for 6 months now, and thinking about another 6 month cycle. I have suffered for 10+ years with endometriosis, and being pain free these last 6 months has been a BIG relief. OK, so I'm a little irritable and could care less about sex (me, who HAD to have it at least once a day, and what is an orgasam again?) I was just wondering if anyone out there has anything positive from their experience with this disease and the treatments available. I am still in child beraing age, and would like the possibility of having another child (even when I feel like wringing my 14 year old's neck...lol...) IS there life out there.... Answered by Shaneka Yuasa 2 years ago.

Thanks for all your feedback. I actually have decided to not take the Lupron any more. I did have the surgery in July, and I think I'll take a bcp so I don't have a period for a while. After that who knows...maybe someone will figure out a cure for this dreadful diesase and we can all be pain free!!! LOL.... As far as bleeding with the Lupron, after the first month, I had no bleeding, except when I missed an appointment for a shot. Even 2 days late, and a little spotting, so don't miss your appointment. The only real side effects I have had is lack of sex drive and response as well as hot flashes...Take the add back therapy, that help balance my emotions as well as stop the flashes. GL all!!!! Thanks again for sharing Answered by Lucretia Sibayan 2 years ago.

P.S I really have had Endo symptoms since the onset of menses at age 10. I began taking the pill at 13 until I was 19, then became pregnant with my son. I'm now 34. The pill lessened my symptoms, but was still told it was in my head. I DID exercises, relaxation techniques, the WHOLE gammet. I always felt as if I was a wimp, no one else cried like I did. And as I got older, Dr's told me the heavy flow was "normal"...What part of a box of pads a day and even several tampons is "normal"? I don't know... GL all, let's prey for a cure!!! Answered by Lyndsay Gerpheide 2 years ago.

Here's my story, I was diagnosed officially with endometriosis in 2003. I beleive I had it all along but it started to affect my daily life in 2001, during my pregnancy. I chased for two years for a diagnosis, I'm sure your familiar with the run around and hassles that go with that.. and finally got a doctor to do a diagnostic lap. so I got the lap. and sure enough it was what I had suspected all along--- Endo. She didn't treat it because she felt that doing so wouldn't do any good. and it's a good thing that she didnt because she definately wasn't qualified. (which I'll explain why in a moment) so now I had a diagnosis I did tons of research, spent countless hours on the internet reading through hundreds of research articles and personal experiences about endo. I talked with lots of endo sufferers and looked into all the options. My doctor put me on bcp's which I knew weren't going to do a thing (I was already on those and they didn't help) after reading up on the options I decided against lupron. Too many long term negatives for short term relief. But I knew I had to do something because I was surviving on vicodin and tylenol to get me out of bed and to help me go to sleep at night and that was beginning to fail me. I was a shell of the person I was before. I couldn't enjoy any of the things I used to. So, after all my research and talking with different people, I decided on excision, next I had to pick the surgeon. I chose someone who is known nationally and happened to be only 3 hours away. So I called and did a few consultations over the phone and decided to set up surgury with Dr. Cook. But I would have to wait 6 months before my insurance would pay any of it. So I decided to take seasonale during that time to try and help me cope in the meantime. It did help more than just regular bcp's and it was wonderful to only have a period every 4 months. Surgury was on september 9th 2004 and endo was removed from the sigmoid colon, both ureturs, pelvic wall, and a few various other places scattered in the pelvic area. There was actually endo and scar tissue wrapped around the sigmoid colon and adhering it to the pelvic wall. In my original diagnostic lap. my previous gyn had said that my right ovary was covered in scar tissue, when actually, both my ovaries were completely healthy no endo or scar tissue anywhere on them so if she had removed the endo from my "ovary" or tried to remove that "ovary" (which was actually my sigmoid colon)since it was so badly covered, she could have been trying to remove part of my bowels! Causing bowel contents to spill into the abdomen which may have killed me. But anyway, since the afternoon of september 9th 2004 (after my surgery) I have been free of endometriosis pain. this september will be 3 years and it has been wonderful. I was able to have another child and was able to return to the physically active life that I had before endo reared it's ugly head. So that's my story, I appologize for how long it is (and this is the condensed version!) but thanks for reading this far and I hope that it helps in some way. Answered by Winston Antonia 2 years ago.

I just started on the Lupron Depot 2 months ago. I have questions- how long did you have bleeding with the shot? My GYN says this is normal and can last for several months. At first mine was just spotting now it is like a normal period, minus the severe endo pain. I was diagnosed with Endometriosis in January after being told for more then a year that I had mental issues that was causing my severe pain each month. The docs exact words were that "all menstraul pain that women have are in their heads"! He finally agreed to a pelvic ultrasound and we found two masses on both my ovaries. He referred me then to a GYN. I've only seen her 3 times, once for a consult, then a laproscopy then for my Lupron. Then has been no follow up to see if the endo has stopped spreading or were else it is. Do you have leg pain from were they gave you the shot? My hip and leg hurt on the side I had the spot on. And do you have headaches? I have severe migraines almost every other day. I had migraines before but not this frequently. as for the side affects, so far it's just leg pain, headaches and the bleeding. My sex drive hasn't decreased, but I am moodier and have had a few hot flashes. Thanks for listening and hopefully answer my questions too. Sorry I couldn't anwer yours. Answered by Angelic Yerty 2 years ago.

I have been suffering from Endo for a LONG time. I was mis diagnosed with an ovarian cyst, appendicitis(which led to that being removed), and a turn muscle in my abdomen. It wasn't until Feb. of this year that i have actually been diagnosed with endo. I have heard way too many horror stories about people on Lupron. Way more negative stuff than positive. So, i decided to go all natural. No pain pills or injections or anything(while still under the safe supervision of my gyn). Deep tissue massage, acupuncture, and yoga have helped me significantly. These things take time to start working, so in the mean time i took a hot bath every night, drank hot tea, and practiced relaxation to help me get rid of the pain. I have run into skepticism about my way of dealing with the pain- but again- its my way. It may not work for you, but before you continue with a harsh chemical in your body- at least try going natural for a while. I also want to have children soon and i do not want to put anymore unnatural things into my body. Give it a try and you may be pleasantly surprised! Answered by Penni Melendres 2 years ago.


Lupron Depot---help!!!?
I have endometriosis. Last Thursday I received my second shot of Lupron Depot, and my gyn did some blood work to determine my estrogen levels because I had breakthrough bleeding that didn't end. It was just some dark brown discharge, but sometimes it would be tinged pink.So, my estrogen levels were... Asked by Keena Leconte 2 years ago.

I have endometriosis. Last Thursday I received my second shot of Lupron Depot, and my gyn did some blood work to determine my estrogen levels because I had breakthrough bleeding that didn't end. It was just some dark brown discharge, but sometimes it would be tinged pink. So, my estrogen levels were determined to be a bit high, so three days ago I went back to get a tiny bit more Lupron in hopes of stopping the breakthrough bleeding. I noticed a change within just a few hours...the discharge had become much lighter in color. And throughout wednesday and thursday it remained lighter. Then this morning I noticed that it had gotten a bit darker, and just a few minutes ago I noticed a tiny bit of obviously red blood in my underpants. Should I be concerned? Should I tell my mom? I'm really nervous. Answered by Matthew Ditullio 2 years ago.

I have taken lupron depot before too because I also have Endometriosis. Are you having bad pelvic cramping with the spotting? You should wear panti liners for the blood spotting. You have not been on Lupron very long and it takes awhile for your periods to stop. So you shouldn't be concerned over a little bit of spotting. But if you are getting severe cramping with it, then please tell your mom and call your doctor's office right away. Lupron has bad side effects that can make you sick, I believe nausea was one of the worst side effects. At some point you may not be able to take it anymore, when you can no longer tolerate the side effects. I feel so sorry for you honey, having Endometriosis. It is a lifetime of chronic pelvic pain. They can treat it, but they can NEVER make it go away. So eventually when you are older they'll want to remove your uterus to stop your periods. But before they do that, they want to give you the chance to have children later in Life if that is what you want. Because I've had this disease all of my Life, I really can sympathize with you. Best of luck! Answered by Aubrey Kudlacik 2 years ago.


Anyone else taken Lupron Depot?
I'm going to be going on this in a couple of weeks. I just wanted to know if anyone else has had experience with this. I've done the research, I know the side effects, but nothing else has worked for my endometriosis. I had surgery two months ago to have it removed and I'm going on Lupron so it... Asked by Aleshia Wanders 2 years ago.

I'm going to be going on this in a couple of weeks. I just wanted to know if anyone else has had experience with this. I've done the research, I know the side effects, but nothing else has worked for my endometriosis. I had surgery two months ago to have it removed and I'm going on Lupron so it won't come back. Answered by Ruthe Gretz 2 years ago.


Any thoughts on the lupron depot shots?
I'm 18 years old and was diagnosed and treated for stage three endo about 7 months ago and my symptoms are returning tenfold. I saw my OB/GYN today and she told me she was really concerned about this and told me my best course of treatment would be to have a second laproscopy and follow it directly with the... Asked by Faith Mcglinn 2 years ago.

I'm 18 years old and was diagnosed and treated for stage three endo about 7 months ago and my symptoms are returning tenfold. I saw my OB/GYN today and she told me she was really concerned about this and told me my best course of treatment would be to have a second laproscopy and follow it directly with the Lupron Depot shot for six months (one shot every three months). Does anyone have a success stoy? Or a horror story maybe? Please help!!! Answered by Mitchel Mannon 2 years ago.

Dear Chickedee, I do NOT recommend Lupron Depot Injections to anyone, but for someone as young as you, I think your Doctor really needs to get on the web and do his/her homework. I was 38 when I received my one + only 3 month shot of Lupron. It did not help my pain at all - it actually caused many new pains. I went from being a firefighter/EMT to a woman who is now filing for disability due to the havoc Lupron created by shutting down my master gland. Google Lupron Victims and you will find a yahoo group that can direct you to a lupron research site, which has many links to news srories, court caseses, etc. Also, please always keep in mind that Lupron is not a cure! Your relief will be temporary, but there's a good chance your side effects will last a lifetime. Good luck! Answered by Vena Lulas 2 years ago.


Lupron depot?
complcations with long use?i haveon this for almost 9 years Asked by Jefferey Trusillo 2 years ago.

I was on it about 13 years ago. I didn't have any problems with it other than it shut down my cycles for those 6 months. You'll be fine. After those, you should consider Seasonale birth control. I've been on that for the last 2 years for my endometriosis. Before that I was on the depo provera shots for 9 years Answered by Shakia Gawlik 2 years ago.


Has anybody ever taken the lupron depot shot and what were the side effects?
would you recommend taking the injection to cure the endometriosis? Asked by Daren Nienow 2 years ago.

I had 3 lupron depot before I couldnt stand them anymore. My pain got worse with the shots not better. Then there was the hot flashes and mood swings. I wouldnt recommend the shots but that was just experience it might work for you. Answered by Yung Harada 2 years ago.

I tried it for two months and it did absolutely nothing except make me more miserable. A friend of mine had them for six months and she was worse off than me. I remember having hot flashes and night sweats that were far worse than actual menopause. The shot definitely did not cure my endometriosis. I ended up having a total hysterectomy which was far better than those awful shots. Maybe other people have had good results with Lupron but I did not. Good Luck!! Answered by Milan Voelz 2 years ago.


Lupron depot shot for women?
has anyone heard, or had the lupron depot shot for endometriosis and what were your or there expreince with it? i am about to get the shot and it last for 6 months Asked by Sanda Albanez 2 years ago.

Lupron Depot Shot Answered by Scarlet Deyarmond 2 years ago.

HI, wife had it and it was the worst thing going. she gained a ton of weight and has never lost it. it basiclaly is putting you into menepause chemicaly induced for 6 months since the endo feeds off your estrogen. they put you in menepause so that you do not produce the estrogen, pregancy will do the same thing but you may not want to get prego now. The hormones really messed with her, she had bad diarea and her periods were all messed up for a long time after. And then the endo came right back. Then the doc suggested cutting the nerve to her uterus so at least she would not feel the pain, yeah thats a real cure doc. anyway- she found an applied kinesiaologist who worked with her on the endo and she has been clr ever since. Hope this has helped. email me if you want to chat more. trialtoid@yahoo.com Answered by Hollis Sarellano 2 years ago.

I was on it about 13 years ago. I didn't have any problems with it other than it shut down my cycles for those 6 months. You'll be fine. After those, you should consider Seasonale birth control. I've been on that for the last 2 years for my endometriosis. Before that I was on the depo provera shots for 9 years Answered by Wen Flether 2 years ago.

I had the shot about 4 years ago. I did have some menopausal symptoms. The shot didn't work for me and I ended up having a hysterectomy about 6 months later. Answered by Billy Callado 2 years ago.

the doc wants me on it to, but it puts you threw menopause. you will get all the symptoms a 45 year old lady has. in tying to avoid this the doc but me on bc pills consistently all 30 days. to stop my peroid. Answered by Ling Comee 2 years ago.


What are your experiences with depot lupron?
I have had horrible side effects from the Depot Lupron shot (3-months doasage), now I am not talking about depot provera, this is a stronger shot to treat endometriosis. It has helped with the pain and lessened the growths, but I have bad hot flashes, weight gain, dryness, the list goes on. Anyone have better... Asked by Myesha Luter 2 years ago.

I have had horrible side effects from the Depot Lupron shot (3-months doasage), now I am not talking about depot provera, this is a stronger shot to treat endometriosis. It has helped with the pain and lessened the growths, but I have bad hot flashes, weight gain, dryness, the list goes on. Anyone have better experience with it? Can anyone suggest an alternative treatment?? BCPs don't work, i tried them already. Answered by Joella Kakaviatos 2 years ago.

Stay FAR away from Lupron!!!!! Endo is an estrogen dominance disease. You need to replace the progesterone that your body is missing with a NATURAL PROGESTERONE CREAM! Email me and I can tell you more. This is some very nasty stuff. :( Here is an article I found.... Be Careful of Lupron for Endometriosis, It Could Be the Kiss of Death By Nicholas Regush This particular saga began a decade ago with an injection of a powerful prescription drug called Lupron. Lynne Millican took the shot for endometriosis, a condition in which pieces of the lining of the uterus are found in other parts of the body, especially in the pelvic cavity. Ten years later, Millican believes she is still suffering from the effects of that injection. Her many symptoms have included the development of a noncancerous tumor, breast cysts, cardiac arrythmias, dizziness, swelling and fatigue. Millican is a registered nurse (and paralegal) living in the Boston area who has become deeply involved in a grass-roots movement to force the U.S. Food and Drug Administration (FDA), and Members of Congress to take a close look at Lupron. The FDA first approved Lupron in 1985 for treatment of men with advanced prostate cancer, and then approved it for treatment of endometriosis in 1990 and uterine fibroids in 1995. "There are thousands in the United States who say they have been victimized by this drug," Millican said, emphasizing that symptoms can be severe, such as tremors, seizures and memory loss. "Many women I know say their symptoms didn't stop when they stopped taking the drug." The FDA has received a wide range of reports of serious side-effects, including death, suspected to be associated with the use of Lupron, but the agency, which holds that the drug's benefits outweigh the risks, does not believe there is sufficient proof to blame Lupron. TAP Pharmaceuticals Inc., jointly owned by Abbott Laboratories and Takeda Chemical Industries of Japan, has steadfastly maintained that Lupron is safe. Millican, who feels that the FDA has been very slow on the draw with Lupron, is also frustrated by the lack of response from almost all of the many senators and representatives in Congress to whom she has written. She has even submitted written testimony to various committee hearings - but to no avail. "It seems that no one but the people who suffer from Lupron are interested in looking into this drug," she said. Millican cannot even recall anyone with an MD degree who has voiced strong concern about Lupron. At the very least, she feels Lupron's safety should be an issue because doctors use it for purposes that were never approved by the FDA. While legal under federal law - once approved for an indication, a drug can be used for other purposes - unapproved use often occurs without the benefit of appropriate safety and efficacy studies. One of Millican's main concerns is Lupron's unapproved use in fertility clinics. The drug is essentially used to suppress female hormones which produce a mature egg. This allows fertility doctors to then induce "controlled" stimulation of multiple eggs. "I am concerned that women who undergo these procedures are not being sufficiently informed about Lupron's side-effects," Millican said. There is even much more at stake, according to Millican. On September 5, she provided testimony to congressional committee hearings on stem cell research, pointing out that the use of Lupron in the process of creating embryos may cause "the very diseases that are being claimed as those diseases necessitating embryonic stem cell research for a cure." Millican finds it hard to swallow that the debate over stem cell research has totally ignored Lupron. Redflagsweekly January 25, 2002 Dr. Mercola's Comment: Folks, Lupron is a disaster drug that in no way shape or form treats the cause of the problem. I have seen it absolutely devastate many women's lives. It is one of the few drugs that I actually cringe when patients tell me that they have taken it. It is my experience and belief that this drug causes permanent neurological damage. This drug needs to be avoided at all costs. It is usually used for endometriosis, which is an estrogen dominance problem and is typically treated quite nicely with natural progesterone, a dietary program, and addressing the emotional stresses which cause the adrenal glands to become impaired Since the adrenals is the main biological of estrogen and progesterone, it is important to restore the proper functioning of this gland. One could take adrenal glandulars, or DHEA and pregnenolone, but those tend to be natural band-aids that don't address the reasons the adrenal became impaired. Answered by Mitzi Jhingree 2 years ago.

I was one of the first guinea pigs to be prescribed Lupron for severe endometriosis in 1995. I had just undergone a laparoscopy and my ob-gyn insisted I try Lupron, especially, he said, because my husband and I had problems conceiving after one year of trying. The mood swings, migraines, dark, thick hair growth in weird places, hot flashes, and memory loss were only the beginning of the side effects I continue to have, 20 years later. I have not begun menopause, and the only baby that was conceived died in-utero at 16 weeks, and I never conceived again in my whole life. My endometriosis has gotten much worse, although I was diagnosed at stage 4 long ago, so I don t know what they would call the stage I have by now? 4+++? The pain has caused me to have to quit my dream job that I went to college for 7 years to work with children as a child psychologist, only to have my doctor reccomend I file for permanent disability because of the amount of pain medications I was taking to make it through the day, and the amount of memory loss I had incurred from Lupron. I have had hot flashes and mood swings for the past 20 years, so that now I need to take medication for PTSD for being attacked by a child at the school I worked with and my son I adopted when I was getting so sick and weak from the pain. I also have so many adhesions and scar tissue, it is really painful to eat a lot at once, because of the pain caused from intestinal blockages from the endometriosis. Please listen to those who have been on the medication and NOT your doctor!! YOu will also be at high risk for osteoporosis by the time you are 50, even if you are on Lupron for only 6 months. It is truly only a rotton bandaid that doctors get bonuses for and pharmaceutical companies get big bucks from the insurance at $2K per shot!! Don t do it! Answered by Von Budnik 2 years ago.

I agree stop taking this drug. I have done two years of research because the dr. keeps pushing it on me. I have continued to tell him no. there was one dr. that said if I don't take it he wouldn't treat me. I didn't have him treat me. Dr.'s are trying to find a way out of solving problems, and this is NOT it. I am still struggling with endo and PCS, but I would rather struggle without the side effects. Best of luck to you. I hope you feel better REALLY soon. Answered by Tonda Gihring 2 years ago.

I have met women who did Lupron and then when they went off of it had issues with extreme fatigue such as due to Chronic Fatigue Syndrome and even fibromyalgia. I haven't met any as of yet that had issues with insomnia or nausea when coming off the medication though. Answered by Ilda Chivalette 2 years ago.


Lupron Depot pros?
In the next few days I will be recieving the Lupron Depot shot (11.25mg). I am 20 years old and have been going through the painful effects of endometrosis for several years.I have read over alot of reviews from this shot and i'm seeing alot of negitive side effects. I get sick really easy so I'm afriad... Asked by Emely Cristaldi 2 years ago.

In the next few days I will be recieving the Lupron Depot shot (11.25mg). I am 20 years old and have been going through the painful effects of endometrosis for several years.I have read over alot of reviews from this shot and i'm seeing alot of negitive side effects. I get sick really easy so I'm afriad that my body will take this shot badly. I had a laproscopy in November of 2006 when I was finally diagnosed with the endo and where they burned out most of it. The next period I had was extreme pain as usual. The only pro that I see in getting this shot is the fact that I will be pain free for 6 months in the period department. I was wondering if there was anymore pros that anyone has experienced fromt his shot. Answered by Sherri Lemond 2 years ago.

No period for six months is about the only pro. I was in the same situation you are. I was diagnosed with endometriosis, and had been through three different pills, a laproscotomy/ DNC, then finally lupron. To be honest, I still experienced some pain while on the shot. The first month the pain was pretty much the same, because of the time it takes for the medicine to work through the body. After that, I didn't have the sharp stabbing pains, but just mild discomfort every once in a while. Expect when you get your shot for you muscles to tighten around the area that the shot was given. (Usually in the behind alternating cheeks each month.) I really didn't feel sick when I got my shot. However, once the medicine was in my body I had pretty much all the side effects of menopause. (After all, that is what you are putting your body through.) Things I experienced where; hot flashes, breast tenderness, dryness in the cervix, decrease in the sex drive, night sweats, and mood swings. Also, my first pap after the lupron course came back abnormal. I am not trying to get you to not have the course done, because it can be beneficial. However, there are many side effects and problems that can come with it. Answered by Albert Miyares 2 years ago.


Endometriosis and Lupron Depot?
P.S I really have had Endo symptoms since the onset of menses at age 10. I began taking the pill at 13 until I was 19, then became pregnant with my son. I'm now 34. The pill lessened my symptoms, but was still told it was in my head.I DID exercises, relaxation techniques, the WHOLE gammet. I always... Asked by Doyle Cattrell 2 years ago.

I have been taking Lupron Depot for 6 months now, and thinking about another 6 month cycle. I have suffered for 10+ years with endometriosis, and being pain free these last 6 months has been a BIG relief. OK, so I'm a little irritable and could care less about sex (me, who HAD to have it at least once a day, and what is an orgasam again?) I was just wondering if anyone out there has anything positive from their experience with this disease and the treatments available. I am still in child beraing age, and would like the possibility of having another child (even when I feel like wringing my 14 year old's neck...lol...) IS there life out there.... Answered by Diane Alires 2 years ago.

Thanks for all your feedback. I actually have decided to not take the Lupron any more. I did have the surgery in July, and I think I'll take a bcp so I don't have a period for a while. After that who knows...maybe someone will figure out a cure for this dreadful diesase and we can all be pain free!!! LOL.... As far as bleeding with the Lupron, after the first month, I had no bleeding, except when I missed an appointment for a shot. Even 2 days late, and a little spotting, so don't miss your appointment. The only real side effects I have had is lack of sex drive and response as well as hot flashes...Take the add back therapy, that help balance my emotions as well as stop the flashes. GL all!!!! Thanks again for sharing Answered by Kevin Klages 2 years ago.

P.S I really have had Endo symptoms since the onset of menses at age 10. I began taking the pill at 13 until I was 19, then became pregnant with my son. I'm now 34. The pill lessened my symptoms, but was still told it was in my head. I DID exercises, relaxation techniques, the WHOLE gammet. I always felt as if I was a wimp, no one else cried like I did. And as I got older, Dr's told me the heavy flow was "normal"...What part of a box of pads a day and even several tampons is "normal"? I don't know... GL all, let's prey for a cure!!! Answered by Modesta Child 2 years ago.

Here's my story, I was diagnosed officially with endometriosis in 2003. I beleive I had it all along but it started to affect my daily life in 2001, during my pregnancy. I chased for two years for a diagnosis, I'm sure your familiar with the run around and hassles that go with that.. and finally got a doctor to do a diagnostic lap. so I got the lap. and sure enough it was what I had suspected all along--- Endo. She didn't treat it because she felt that doing so wouldn't do any good. and it's a good thing that she didnt because she definately wasn't qualified. (which I'll explain why in a moment) so now I had a diagnosis I did tons of research, spent countless hours on the internet reading through hundreds of research articles and personal experiences about endo. I talked with lots of endo sufferers and looked into all the options. My doctor put me on bcp's which I knew weren't going to do a thing (I was already on those and they didn't help) after reading up on the options I decided against lupron. Too many long term negatives for short term relief. But I knew I had to do something because I was surviving on vicodin and tylenol to get me out of bed and to help me go to sleep at night and that was beginning to fail me. I was a shell of the person I was before. I couldn't enjoy any of the things I used to. So, after all my research and talking with different people, I decided on excision, next I had to pick the surgeon. I chose someone who is known nationally and happened to be only 3 hours away. So I called and did a few consultations over the phone and decided to set up surgury with Dr. Cook. But I would have to wait 6 months before my insurance would pay any of it. So I decided to take seasonale during that time to try and help me cope in the meantime. It did help more than just regular bcp's and it was wonderful to only have a period every 4 months. Surgury was on september 9th 2004 and endo was removed from the sigmoid colon, both ureturs, pelvic wall, and a few various other places scattered in the pelvic area. There was actually endo and scar tissue wrapped around the sigmoid colon and adhering it to the pelvic wall. In my original diagnostic lap. my previous gyn had said that my right ovary was covered in scar tissue, when actually, both my ovaries were completely healthy no endo or scar tissue anywhere on them so if she had removed the endo from my "ovary" or tried to remove that "ovary" (which was actually my sigmoid colon)since it was so badly covered, she could have been trying to remove part of my bowels! Causing bowel contents to spill into the abdomen which may have killed me. But anyway, since the afternoon of september 9th 2004 (after my surgery) I have been free of endometriosis pain. this september will be 3 years and it has been wonderful. I was able to have another child and was able to return to the physically active life that I had before endo reared it's ugly head. So that's my story, I appologize for how long it is (and this is the condensed version!) but thanks for reading this far and I hope that it helps in some way. Answered by Donna Busche 2 years ago.

I just started on the Lupron Depot 2 months ago. I have questions- how long did you have bleeding with the shot? My GYN says this is normal and can last for several months. At first mine was just spotting now it is like a normal period, minus the severe endo pain. I was diagnosed with Endometriosis in January after being told for more then a year that I had mental issues that was causing my severe pain each month. The docs exact words were that "all menstraul pain that women have are in their heads"! He finally agreed to a pelvic ultrasound and we found two masses on both my ovaries. He referred me then to a GYN. I've only seen her 3 times, once for a consult, then a laproscopy then for my Lupron. Then has been no follow up to see if the endo has stopped spreading or were else it is. Do you have leg pain from were they gave you the shot? My hip and leg hurt on the side I had the spot on. And do you have headaches? I have severe migraines almost every other day. I had migraines before but not this frequently. as for the side affects, so far it's just leg pain, headaches and the bleeding. My sex drive hasn't decreased, but I am moodier and have had a few hot flashes. Thanks for listening and hopefully answer my questions too. Sorry I couldn't anwer yours. Answered by Patrina Bausch 2 years ago.

I have been suffering from Endo for a LONG time. I was mis diagnosed with an ovarian cyst, appendicitis(which led to that being removed), and a turn muscle in my abdomen. It wasn't until Feb. of this year that i have actually been diagnosed with endo. I have heard way too many horror stories about people on Lupron. Way more negative stuff than positive. So, i decided to go all natural. No pain pills or injections or anything(while still under the safe supervision of my gyn). Deep tissue massage, acupuncture, and yoga have helped me significantly. These things take time to start working, so in the mean time i took a hot bath every night, drank hot tea, and practiced relaxation to help me get rid of the pain. I have run into skepticism about my way of dealing with the pain- but again- its my way. It may not work for you, but before you continue with a harsh chemical in your body- at least try going natural for a while. I also want to have children soon and i do not want to put anymore unnatural things into my body. Give it a try and you may be pleasantly surprised! Answered by Suzy Kasperek 2 years ago.


Lupron Depot---help!!!?
I have endometriosis. Last Thursday I received my second shot of Lupron Depot, and my gyn did some blood work to determine my estrogen levels because I had breakthrough bleeding that didn't end. It was just some dark brown discharge, but sometimes it would be tinged pink.So, my estrogen levels were... Asked by Janeen Gagen 2 years ago.

I have endometriosis. Last Thursday I received my second shot of Lupron Depot, and my gyn did some blood work to determine my estrogen levels because I had breakthrough bleeding that didn't end. It was just some dark brown discharge, but sometimes it would be tinged pink. So, my estrogen levels were determined to be a bit high, so three days ago I went back to get a tiny bit more Lupron in hopes of stopping the breakthrough bleeding. I noticed a change within just a few hours...the discharge had become much lighter in color. And throughout wednesday and thursday it remained lighter. Then this morning I noticed that it had gotten a bit darker, and just a few minutes ago I noticed a tiny bit of obviously red blood in my underpants. Should I be concerned? Should I tell my mom? I'm really nervous. Answered by Ivory Ailes 2 years ago.

I have taken lupron depot before too because I also have Endometriosis. Are you having bad pelvic cramping with the spotting? You should wear panti liners for the blood spotting. You have not been on Lupron very long and it takes awhile for your periods to stop. So you shouldn't be concerned over a little bit of spotting. But if you are getting severe cramping with it, then please tell your mom and call your doctor's office right away. Lupron has bad side effects that can make you sick, I believe nausea was one of the worst side effects. At some point you may not be able to take it anymore, when you can no longer tolerate the side effects. I feel so sorry for you honey, having Endometriosis. It is a lifetime of chronic pelvic pain. They can treat it, but they can NEVER make it go away. So eventually when you are older they'll want to remove your uterus to stop your periods. But before they do that, they want to give you the chance to have children later in Life if that is what you want. Because I've had this disease all of my Life, I really can sympathize with you. Best of luck! Answered by Sharlene Angwin 2 years ago.


Anyone else taken Lupron Depot?
I'm going to be going on this in a couple of weeks. I just wanted to know if anyone else has had experience with this. I've done the research, I know the side effects, but nothing else has worked for my endometriosis. I had surgery two months ago to have it removed and I'm going on Lupron so it... Asked by Tien Beese 2 years ago.

I'm going to be going on this in a couple of weeks. I just wanted to know if anyone else has had experience with this. I've done the research, I know the side effects, but nothing else has worked for my endometriosis. I had surgery two months ago to have it removed and I'm going on Lupron so it won't come back. Answered by Christian Magdefrau 2 years ago.


Any thoughts on the lupron depot shots?
I'm 18 years old and was diagnosed and treated for stage three endo about 7 months ago and my symptoms are returning tenfold. I saw my OB/GYN today and she told me she was really concerned about this and told me my best course of treatment would be to have a second laproscopy and follow it directly with the... Asked by Keli Rispoli 2 years ago.

I'm 18 years old and was diagnosed and treated for stage three endo about 7 months ago and my symptoms are returning tenfold. I saw my OB/GYN today and she told me she was really concerned about this and told me my best course of treatment would be to have a second laproscopy and follow it directly with the Lupron Depot shot for six months (one shot every three months). Does anyone have a success stoy? Or a horror story maybe? Please help!!! Answered by Caleb Rodamis 2 years ago.

Dear Chickedee, I do NOT recommend Lupron Depot Injections to anyone, but for someone as young as you, I think your Doctor really needs to get on the web and do his/her homework. I was 38 when I received my one + only 3 month shot of Lupron. It did not help my pain at all - it actually caused many new pains. I went from being a firefighter/EMT to a woman who is now filing for disability due to the havoc Lupron created by shutting down my master gland. Google Lupron Victims and you will find a yahoo group that can direct you to a lupron research site, which has many links to news srories, court caseses, etc. Also, please always keep in mind that Lupron is not a cure! Your relief will be temporary, but there's a good chance your side effects will last a lifetime. Good luck! Answered by Pauline Abramek 2 years ago.


Lupron depot?
complcations with long use?i haveon this for almost 9 years Asked by Camellia Orpen 2 years ago.

I was on it about 13 years ago. I didn't have any problems with it other than it shut down my cycles for those 6 months. You'll be fine. After those, you should consider Seasonale birth control. I've been on that for the last 2 years for my endometriosis. Before that I was on the depo provera shots for 9 years Answered by Daniela Kingdon 2 years ago.


Has anybody ever taken the lupron depot shot and what were the side effects?
would you recommend taking the injection to cure the endometriosis? Asked by Teodoro Calkins 2 years ago.

I had 3 lupron depot before I couldnt stand them anymore. My pain got worse with the shots not better. Then there was the hot flashes and mood swings. I wouldnt recommend the shots but that was just experience it might work for you. Answered by Rickie Lounsbery 2 years ago.

I tried it for two months and it did absolutely nothing except make me more miserable. A friend of mine had them for six months and she was worse off than me. I remember having hot flashes and night sweats that were far worse than actual menopause. The shot definitely did not cure my endometriosis. I ended up having a total hysterectomy which was far better than those awful shots. Maybe other people have had good results with Lupron but I did not. Good Luck!! Answered by Donald Dziuba 2 years ago.


Lupron depot shot for women?
has anyone heard, or had the lupron depot shot for endometriosis and what were your or there expreince with it? i am about to get the shot and it last for 6 months Asked by Sue Gaiters 2 years ago.

Lupron Depot Shot Answered by Lauren Demik 2 years ago.

HI, wife had it and it was the worst thing going. she gained a ton of weight and has never lost it. it basiclaly is putting you into menepause chemicaly induced for 6 months since the endo feeds off your estrogen. they put you in menepause so that you do not produce the estrogen, pregancy will do the same thing but you may not want to get prego now. The hormones really messed with her, she had bad diarea and her periods were all messed up for a long time after. And then the endo came right back. Then the doc suggested cutting the nerve to her uterus so at least she would not feel the pain, yeah thats a real cure doc. anyway- she found an applied kinesiaologist who worked with her on the endo and she has been clr ever since. Hope this has helped. email me if you want to chat more. trialtoid@yahoo.com Answered by Gisela Sossong 2 years ago.

I was on it about 13 years ago. I didn't have any problems with it other than it shut down my cycles for those 6 months. You'll be fine. After those, you should consider Seasonale birth control. I've been on that for the last 2 years for my endometriosis. Before that I was on the depo provera shots for 9 years Answered by Ruben Borozny 2 years ago.

I had the shot about 4 years ago. I did have some menopausal symptoms. The shot didn't work for me and I ended up having a hysterectomy about 6 months later. Answered by Karyl Novik 2 years ago.

the doc wants me on it to, but it puts you threw menopause. you will get all the symptoms a 45 year old lady has. in tying to avoid this the doc but me on bc pills consistently all 30 days. to stop my peroid. Answered by Maggie Breger 2 years ago.


What are your experiences with depot lupron?
I have had horrible side effects from the Depot Lupron shot (3-months doasage), now I am not talking about depot provera, this is a stronger shot to treat endometriosis. It has helped with the pain and lessened the growths, but I have bad hot flashes, weight gain, dryness, the list goes on. Anyone have better... Asked by Kip Eylicio 2 years ago.

I have had horrible side effects from the Depot Lupron shot (3-months doasage), now I am not talking about depot provera, this is a stronger shot to treat endometriosis. It has helped with the pain and lessened the growths, but I have bad hot flashes, weight gain, dryness, the list goes on. Anyone have better experience with it? Can anyone suggest an alternative treatment?? BCPs don't work, i tried them already. Answered by Genna Janofsky 2 years ago.

Stay FAR away from Lupron!!!!! Endo is an estrogen dominance disease. You need to replace the progesterone that your body is missing with a NATURAL PROGESTERONE CREAM! Email me and I can tell you more. This is some very nasty stuff. :( Here is an article I found.... Be Careful of Lupron for Endometriosis, It Could Be the Kiss of Death By Nicholas Regush This particular saga began a decade ago with an injection of a powerful prescription drug called Lupron. Lynne Millican took the shot for endometriosis, a condition in which pieces of the lining of the uterus are found in other parts of the body, especially in the pelvic cavity. Ten years later, Millican believes she is still suffering from the effects of that injection. Her many symptoms have included the development of a noncancerous tumor, breast cysts, cardiac arrythmias, dizziness, swelling and fatigue. Millican is a registered nurse (and paralegal) living in the Boston area who has become deeply involved in a grass-roots movement to force the U.S. Food and Drug Administration (FDA), and Members of Congress to take a close look at Lupron. The FDA first approved Lupron in 1985 for treatment of men with advanced prostate cancer, and then approved it for treatment of endometriosis in 1990 and uterine fibroids in 1995. "There are thousands in the United States who say they have been victimized by this drug," Millican said, emphasizing that symptoms can be severe, such as tremors, seizures and memory loss. "Many women I know say their symptoms didn't stop when they stopped taking the drug." The FDA has received a wide range of reports of serious side-effects, including death, suspected to be associated with the use of Lupron, but the agency, which holds that the drug's benefits outweigh the risks, does not believe there is sufficient proof to blame Lupron. TAP Pharmaceuticals Inc., jointly owned by Abbott Laboratories and Takeda Chemical Industries of Japan, has steadfastly maintained that Lupron is safe. Millican, who feels that the FDA has been very slow on the draw with Lupron, is also frustrated by the lack of response from almost all of the many senators and representatives in Congress to whom she has written. She has even submitted written testimony to various committee hearings - but to no avail. "It seems that no one but the people who suffer from Lupron are interested in looking into this drug," she said. Millican cannot even recall anyone with an MD degree who has voiced strong concern about Lupron. At the very least, she feels Lupron's safety should be an issue because doctors use it for purposes that were never approved by the FDA. While legal under federal law - once approved for an indication, a drug can be used for other purposes - unapproved use often occurs without the benefit of appropriate safety and efficacy studies. One of Millican's main concerns is Lupron's unapproved use in fertility clinics. The drug is essentially used to suppress female hormones which produce a mature egg. This allows fertility doctors to then induce "controlled" stimulation of multiple eggs. "I am concerned that women who undergo these procedures are not being sufficiently informed about Lupron's side-effects," Millican said. There is even much more at stake, according to Millican. On September 5, she provided testimony to congressional committee hearings on stem cell research, pointing out that the use of Lupron in the process of creating embryos may cause "the very diseases that are being claimed as those diseases necessitating embryonic stem cell research for a cure." Millican finds it hard to swallow that the debate over stem cell research has totally ignored Lupron. Redflagsweekly January 25, 2002 Dr. Mercola's Comment: Folks, Lupron is a disaster drug that in no way shape or form treats the cause of the problem. I have seen it absolutely devastate many women's lives. It is one of the few drugs that I actually cringe when patients tell me that they have taken it. It is my experience and belief that this drug causes permanent neurological damage. This drug needs to be avoided at all costs. It is usually used for endometriosis, which is an estrogen dominance problem and is typically treated quite nicely with natural progesterone, a dietary program, and addressing the emotional stresses which cause the adrenal glands to become impaired Since the adrenals is the main biological of estrogen and progesterone, it is important to restore the proper functioning of this gland. One could take adrenal glandulars, or DHEA and pregnenolone, but those tend to be natural band-aids that don't address the reasons the adrenal became impaired. Answered by Eden Deniz 2 years ago.

I was one of the first guinea pigs to be prescribed Lupron for severe endometriosis in 1995. I had just undergone a laparoscopy and my ob-gyn insisted I try Lupron, especially, he said, because my husband and I had problems conceiving after one year of trying. The mood swings, migraines, dark, thick hair growth in weird places, hot flashes, and memory loss were only the beginning of the side effects I continue to have, 20 years later. I have not begun menopause, and the only baby that was conceived died in-utero at 16 weeks, and I never conceived again in my whole life. My endometriosis has gotten much worse, although I was diagnosed at stage 4 long ago, so I don t know what they would call the stage I have by now? 4+++? The pain has caused me to have to quit my dream job that I went to college for 7 years to work with children as a child psychologist, only to have my doctor reccomend I file for permanent disability because of the amount of pain medications I was taking to make it through the day, and the amount of memory loss I had incurred from Lupron. I have had hot flashes and mood swings for the past 20 years, so that now I need to take medication for PTSD for being attacked by a child at the school I worked with and my son I adopted when I was getting so sick and weak from the pain. I also have so many adhesions and scar tissue, it is really painful to eat a lot at once, because of the pain caused from intestinal blockages from the endometriosis. Please listen to those who have been on the medication and NOT your doctor!! YOu will also be at high risk for osteoporosis by the time you are 50, even if you are on Lupron for only 6 months. It is truly only a rotton bandaid that doctors get bonuses for and pharmaceutical companies get big bucks from the insurance at $2K per shot!! Don t do it! Answered by Aura Kjelland 2 years ago.

I agree stop taking this drug. I have done two years of research because the dr. keeps pushing it on me. I have continued to tell him no. there was one dr. that said if I don't take it he wouldn't treat me. I didn't have him treat me. Dr.'s are trying to find a way out of solving problems, and this is NOT it. I am still struggling with endo and PCS, but I would rather struggle without the side effects. Best of luck to you. I hope you feel better REALLY soon. Answered by Ray Harlem 2 years ago.

I have met women who did Lupron and then when they went off of it had issues with extreme fatigue such as due to Chronic Fatigue Syndrome and even fibromyalgia. I haven't met any as of yet that had issues with insomnia or nausea when coming off the medication though. Answered by Casie Tyndal 2 years ago.


Lupron Depot pros?
In the next few days I will be recieving the Lupron Depot shot (11.25mg). I am 20 years old and have been going through the painful effects of endometrosis for several years.I have read over alot of reviews from this shot and i'm seeing alot of negitive side effects. I get sick really easy so I'm afriad... Asked by Lucina Crivello 2 years ago.

In the next few days I will be recieving the Lupron Depot shot (11.25mg). I am 20 years old and have been going through the painful effects of endometrosis for several years.I have read over alot of reviews from this shot and i'm seeing alot of negitive side effects. I get sick really easy so I'm afriad that my body will take this shot badly. I had a laproscopy in November of 2006 when I was finally diagnosed with the endo and where they burned out most of it. The next period I had was extreme pain as usual. The only pro that I see in getting this shot is the fact that I will be pain free for 6 months in the period department. I was wondering if there was anymore pros that anyone has experienced fromt his shot. Answered by Rashad Blumenschein 2 years ago.

No period for six months is about the only pro. I was in the same situation you are. I was diagnosed with endometriosis, and had been through three different pills, a laproscotomy/ DNC, then finally lupron. To be honest, I still experienced some pain while on the shot. The first month the pain was pretty much the same, because of the time it takes for the medicine to work through the body. After that, I didn't have the sharp stabbing pains, but just mild discomfort every once in a while. Expect when you get your shot for you muscles to tighten around the area that the shot was given. (Usually in the behind alternating cheeks each month.) I really didn't feel sick when I got my shot. However, once the medicine was in my body I had pretty much all the side effects of menopause. (After all, that is what you are putting your body through.) Things I experienced where; hot flashes, breast tenderness, dryness in the cervix, decrease in the sex drive, night sweats, and mood swings. Also, my first pap after the lupron course came back abnormal. I am not trying to get you to not have the course done, because it can be beneficial. However, there are many side effects and problems that can come with it. Answered by Juliane Mauricio 2 years ago.


Endometriosis and Lupron Depot?
P.S I really have had Endo symptoms since the onset of menses at age 10. I began taking the pill at 13 until I was 19, then became pregnant with my son. I'm now 34. The pill lessened my symptoms, but was still told it was in my head.I DID exercises, relaxation techniques, the WHOLE gammet. I always... Asked by Marvella Coonrod 2 years ago.

I have been taking Lupron Depot for 6 months now, and thinking about another 6 month cycle. I have suffered for 10+ years with endometriosis, and being pain free these last 6 months has been a BIG relief. OK, so I'm a little irritable and could care less about sex (me, who HAD to have it at least once a day, and what is an orgasam again?) I was just wondering if anyone out there has anything positive from their experience with this disease and the treatments available. I am still in child beraing age, and would like the possibility of having another child (even when I feel like wringing my 14 year old's neck...lol...) IS there life out there.... Answered by Milda Biagi 2 years ago.

Thanks for all your feedback. I actually have decided to not take the Lupron any more. I did have the surgery in July, and I think I'll take a bcp so I don't have a period for a while. After that who knows...maybe someone will figure out a cure for this dreadful diesase and we can all be pain free!!! LOL.... As far as bleeding with the Lupron, after the first month, I had no bleeding, except when I missed an appointment for a shot. Even 2 days late, and a little spotting, so don't miss your appointment. The only real side effects I have had is lack of sex drive and response as well as hot flashes...Take the add back therapy, that help balance my emotions as well as stop the flashes. GL all!!!! Thanks again for sharing Answered by Delta Humes 2 years ago.

P.S I really have had Endo symptoms since the onset of menses at age 10. I began taking the pill at 13 until I was 19, then became pregnant with my son. I'm now 34. The pill lessened my symptoms, but was still told it was in my head. I DID exercises, relaxation techniques, the WHOLE gammet. I always felt as if I was a wimp, no one else cried like I did. And as I got older, Dr's told me the heavy flow was "normal"...What part of a box of pads a day and even several tampons is "normal"? I don't know... GL all, let's prey for a cure!!! Answered by Jennell Peavy 2 years ago.

Here's my story, I was diagnosed officially with endometriosis in 2003. I beleive I had it all along but it started to affect my daily life in 2001, during my pregnancy. I chased for two years for a diagnosis, I'm sure your familiar with the run around and hassles that go with that.. and finally got a doctor to do a diagnostic lap. so I got the lap. and sure enough it was what I had suspected all along--- Endo. She didn't treat it because she felt that doing so wouldn't do any good. and it's a good thing that she didnt because she definately wasn't qualified. (which I'll explain why in a moment) so now I had a diagnosis I did tons of research, spent countless hours on the internet reading through hundreds of research articles and personal experiences about endo. I talked with lots of endo sufferers and looked into all the options. My doctor put me on bcp's which I knew weren't going to do a thing (I was already on those and they didn't help) after reading up on the options I decided against lupron. Too many long term negatives for short term relief. But I knew I had to do something because I was surviving on vicodin and tylenol to get me out of bed and to help me go to sleep at night and that was beginning to fail me. I was a shell of the person I was before. I couldn't enjoy any of the things I used to. So, after all my research and talking with different people, I decided on excision, next I had to pick the surgeon. I chose someone who is known nationally and happened to be only 3 hours away. So I called and did a few consultations over the phone and decided to set up surgury with Dr. Cook. But I would have to wait 6 months before my insurance would pay any of it. So I decided to take seasonale during that time to try and help me cope in the meantime. It did help more than just regular bcp's and it was wonderful to only have a period every 4 months. Surgury was on september 9th 2004 and endo was removed from the sigmoid colon, both ureturs, pelvic wall, and a few various other places scattered in the pelvic area. There was actually endo and scar tissue wrapped around the sigmoid colon and adhering it to the pelvic wall. In my original diagnostic lap. my previous gyn had said that my right ovary was covered in scar tissue, when actually, both my ovaries were completely healthy no endo or scar tissue anywhere on them so if she had removed the endo from my "ovary" or tried to remove that "ovary" (which was actually my sigmoid colon)since it was so badly covered, she could have been trying to remove part of my bowels! Causing bowel contents to spill into the abdomen which may have killed me. But anyway, since the afternoon of september 9th 2004 (after my surgery) I have been free of endometriosis pain. this september will be 3 years and it has been wonderful. I was able to have another child and was able to return to the physically active life that I had before endo reared it's ugly head. So that's my story, I appologize for how long it is (and this is the condensed version!) but thanks for reading this far and I hope that it helps in some way. Answered by Coleman Rodgers 2 years ago.

I just started on the Lupron Depot 2 months ago. I have questions- how long did you have bleeding with the shot? My GYN says this is normal and can last for several months. At first mine was just spotting now it is like a normal period, minus the severe endo pain. I was diagnosed with Endometriosis in January after being told for more then a year that I had mental issues that was causing my severe pain each month. The docs exact words were that "all menstraul pain that women have are in their heads"! He finally agreed to a pelvic ultrasound and we found two masses on both my ovaries. He referred me then to a GYN. I've only seen her 3 times, once for a consult, then a laproscopy then for my Lupron. Then has been no follow up to see if the endo has stopped spreading or were else it is. Do you have leg pain from were they gave you the shot? My hip and leg hurt on the side I had the spot on. And do you have headaches? I have severe migraines almost every other day. I had migraines before but not this frequently. as for the side affects, so far it's just leg pain, headaches and the bleeding. My sex drive hasn't decreased, but I am moodier and have had a few hot flashes. Thanks for listening and hopefully answer my questions too. Sorry I couldn't anwer yours. Answered by Cletus Linderman 2 years ago.

I have been suffering from Endo for a LONG time. I was mis diagnosed with an ovarian cyst, appendicitis(which led to that being removed), and a turn muscle in my abdomen. It wasn't until Feb. of this year that i have actually been diagnosed with endo. I have heard way too many horror stories about people on Lupron. Way more negative stuff than positive. So, i decided to go all natural. No pain pills or injections or anything(while still under the safe supervision of my gyn). Deep tissue massage, acupuncture, and yoga have helped me significantly. These things take time to start working, so in the mean time i took a hot bath every night, drank hot tea, and practiced relaxation to help me get rid of the pain. I have run into skepticism about my way of dealing with the pain- but again- its my way. It may not work for you, but before you continue with a harsh chemical in your body- at least try going natural for a while. I also want to have children soon and i do not want to put anymore unnatural things into my body. Give it a try and you may be pleasantly surprised! Answered by Eunice Orndorf 2 years ago.


Lupron Depot---help!!!?
I have endometriosis. Last Thursday I received my second shot of Lupron Depot, and my gyn did some blood work to determine my estrogen levels because I had breakthrough bleeding that didn't end. It was just some dark brown discharge, but sometimes it would be tinged pink.So, my estrogen levels were... Asked by Annette Andrepont 2 years ago.

I have endometriosis. Last Thursday I received my second shot of Lupron Depot, and my gyn did some blood work to determine my estrogen levels because I had breakthrough bleeding that didn't end. It was just some dark brown discharge, but sometimes it would be tinged pink. So, my estrogen levels were determined to be a bit high, so three days ago I went back to get a tiny bit more Lupron in hopes of stopping the breakthrough bleeding. I noticed a change within just a few hours...the discharge had become much lighter in color. And throughout wednesday and thursday it remained lighter. Then this morning I noticed that it had gotten a bit darker, and just a few minutes ago I noticed a tiny bit of obviously red blood in my underpants. Should I be concerned? Should I tell my mom? I'm really nervous. Answered by Shan Wageman 2 years ago.

I have taken lupron depot before too because I also have Endometriosis. Are you having bad pelvic cramping with the spotting? You should wear panti liners for the blood spotting. You have not been on Lupron very long and it takes awhile for your periods to stop. So you shouldn't be concerned over a little bit of spotting. But if you are getting severe cramping with it, then please tell your mom and call your doctor's office right away. Lupron has bad side effects that can make you sick, I believe nausea was one of the worst side effects. At some point you may not be able to take it anymore, when you can no longer tolerate the side effects. I feel so sorry for you honey, having Endometriosis. It is a lifetime of chronic pelvic pain. They can treat it, but they can NEVER make it go away. So eventually when you are older they'll want to remove your uterus to stop your periods. But before they do that, they want to give you the chance to have children later in Life if that is what you want. Because I've had this disease all of my Life, I really can sympathize with you. Best of luck! Answered by Camellia Huxtable 2 years ago.


Anyone else taken Lupron Depot?
I'm going to be going on this in a couple of weeks. I just wanted to know if anyone else has had experience with this. I've done the research, I know the side effects, but nothing else has worked for my endometriosis. I had surgery two months ago to have it removed and I'm going on Lupron so it... Asked by Jena Vatterott 2 years ago.

I'm going to be going on this in a couple of weeks. I just wanted to know if anyone else has had experience with this. I've done the research, I know the side effects, but nothing else has worked for my endometriosis. I had surgery two months ago to have it removed and I'm going on Lupron so it won't come back. Answered by Bernard Podratz 2 years ago.


Any thoughts on the lupron depot shots?
I'm 18 years old and was diagnosed and treated for stage three endo about 7 months ago and my symptoms are returning tenfold. I saw my OB/GYN today and she told me she was really concerned about this and told me my best course of treatment would be to have a second laproscopy and follow it directly with the... Asked by Melanie Raskin 2 years ago.

I'm 18 years old and was diagnosed and treated for stage three endo about 7 months ago and my symptoms are returning tenfold. I saw my OB/GYN today and she told me she was really concerned about this and told me my best course of treatment would be to have a second laproscopy and follow it directly with the Lupron Depot shot for six months (one shot every three months). Does anyone have a success stoy? Or a horror story maybe? Please help!!! Answered by Darlena Hanlin 2 years ago.

Dear Chickedee, I do NOT recommend Lupron Depot Injections to anyone, but for someone as young as you, I think your Doctor really needs to get on the web and do his/her homework. I was 38 when I received my one + only 3 month shot of Lupron. It did not help my pain at all - it actually caused many new pains. I went from being a firefighter/EMT to a woman who is now filing for disability due to the havoc Lupron created by shutting down my master gland. Google Lupron Victims and you will find a yahoo group that can direct you to a lupron research site, which has many links to news srories, court caseses, etc. Also, please always keep in mind that Lupron is not a cure! Your relief will be temporary, but there's a good chance your side effects will last a lifetime. Good luck! Answered by Danna Maier 2 years ago.


Lupron depot?
complcations with long use?i haveon this for almost 9 years Asked by Doreen Perris 2 years ago.

I was on it about 13 years ago. I didn't have any problems with it other than it shut down my cycles for those 6 months. You'll be fine. After those, you should consider Seasonale birth control. I've been on that for the last 2 years for my endometriosis. Before that I was on the depo provera shots for 9 years Answered by Keira Azebedo 2 years ago.


Has anybody ever taken the lupron depot shot and what were the side effects?
would you recommend taking the injection to cure the endometriosis? Asked by Asha Piacitelli 2 years ago.

I had 3 lupron depot before I couldnt stand them anymore. My pain got worse with the shots not better. Then there was the hot flashes and mood swings. I wouldnt recommend the shots but that was just experience it might work for you. Answered by Elia Lines 2 years ago.

I tried it for two months and it did absolutely nothing except make me more miserable. A friend of mine had them for six months and she was worse off than me. I remember having hot flashes and night sweats that were far worse than actual menopause. The shot definitely did not cure my endometriosis. I ended up having a total hysterectomy which was far better than those awful shots. Maybe other people have had good results with Lupron but I did not. Good Luck!! Answered by Holly Nishida 2 years ago.


Lupron depot shot for women?
has anyone heard, or had the lupron depot shot for endometriosis and what were your or there expreince with it? i am about to get the shot and it last for 6 months Asked by Ione Scipio 2 years ago.

Lupron Depot Shot Answered by Treena Santore 2 years ago.

HI, wife had it and it was the worst thing going. she gained a ton of weight and has never lost it. it basiclaly is putting you into menepause chemicaly induced for 6 months since the endo feeds off your estrogen. they put you in menepause so that you do not produce the estrogen, pregancy will do the same thing but you may not want to get prego now. The hormones really messed with her, she had bad diarea and her periods were all messed up for a long time after. And then the endo came right back. Then the doc suggested cutting the nerve to her uterus so at least she would not feel the pain, yeah thats a real cure doc. anyway- she found an applied kinesiaologist who worked with her on the endo and she has been clr ever since. Hope this has helped. email me if you want to chat more. trialtoid@yahoo.com Answered by Stefany Deltoro 2 years ago.

I was on it about 13 years ago. I didn't have any problems with it other than it shut down my cycles for those 6 months. You'll be fine. After those, you should consider Seasonale birth control. I've been on that for the last 2 years for my endometriosis. Before that I was on the depo provera shots for 9 years Answered by Dianne Iulianetti 2 years ago.

I had the shot about 4 years ago. I did have some menopausal symptoms. The shot didn't work for me and I ended up having a hysterectomy about 6 months later. Answered by Elliott Napierala 2 years ago.

the doc wants me on it to, but it puts you threw menopause. you will get all the symptoms a 45 year old lady has. in tying to avoid this the doc but me on bc pills consistently all 30 days. to stop my peroid. Answered by Bao Francisque 2 years ago.


What are your experiences with depot lupron?
I have had horrible side effects from the Depot Lupron shot (3-months doasage), now I am not talking about depot provera, this is a stronger shot to treat endometriosis. It has helped with the pain and lessened the growths, but I have bad hot flashes, weight gain, dryness, the list goes on. Anyone have better... Asked by Wava Mehis 2 years ago.

I have had horrible side effects from the Depot Lupron shot (3-months doasage), now I am not talking about depot provera, this is a stronger shot to treat endometriosis. It has helped with the pain and lessened the growths, but I have bad hot flashes, weight gain, dryness, the list goes on. Anyone have better experience with it? Can anyone suggest an alternative treatment?? BCPs don't work, i tried them already. Answered by Hilaria Bartuska 2 years ago.

Stay FAR away from Lupron!!!!! Endo is an estrogen dominance disease. You need to replace the progesterone that your body is missing with a NATURAL PROGESTERONE CREAM! Email me and I can tell you more. This is some very nasty stuff. :( Here is an article I found.... Be Careful of Lupron for Endometriosis, It Could Be the Kiss of Death By Nicholas Regush This particular saga began a decade ago with an injection of a powerful prescription drug called Lupron. Lynne Millican took the shot for endometriosis, a condition in which pieces of the lining of the uterus are found in other parts of the body, especially in the pelvic cavity. Ten years later, Millican believes she is still suffering from the effects of that injection. Her many symptoms have included the development of a noncancerous tumor, breast cysts, cardiac arrythmias, dizziness, swelling and fatigue. Millican is a registered nurse (and paralegal) living in the Boston area who has become deeply involved in a grass-roots movement to force the U.S. Food and Drug Administration (FDA), and Members of Congress to take a close look at Lupron. The FDA first approved Lupron in 1985 for treatment of men with advanced prostate cancer, and then approved it for treatment of endometriosis in 1990 and uterine fibroids in 1995. "There are thousands in the United States who say they have been victimized by this drug," Millican said, emphasizing that symptoms can be severe, such as tremors, seizures and memory loss. "Many women I know say their symptoms didn't stop when they stopped taking the drug." The FDA has received a wide range of reports of serious side-effects, including death, suspected to be associated with the use of Lupron, but the agency, which holds that the drug's benefits outweigh the risks, does not believe there is sufficient proof to blame Lupron. TAP Pharmaceuticals Inc., jointly owned by Abbott Laboratories and Takeda Chemical Industries of Japan, has steadfastly maintained that Lupron is safe. Millican, who feels that the FDA has been very slow on the draw with Lupron, is also frustrated by the lack of response from almost all of the many senators and representatives in Congress to whom she has written. She has even submitted written testimony to various committee hearings - but to no avail. "It seems that no one but the people who suffer from Lupron are interested in looking into this drug," she said. Millican cannot even recall anyone with an MD degree who has voiced strong concern about Lupron. At the very least, she feels Lupron's safety should be an issue because doctors use it for purposes that were never approved by the FDA. While legal under federal law - once approved for an indication, a drug can be used for other purposes - unapproved use often occurs without the benefit of appropriate safety and efficacy studies. One of Millican's main concerns is Lupron's unapproved use in fertility clinics. The drug is essentially used to suppress female hormones which produce a mature egg. This allows fertility doctors to then induce "controlled" stimulation of multiple eggs. "I am concerned that women who undergo these procedures are not being sufficiently informed about Lupron's side-effects," Millican said. There is even much more at stake, according to Millican. On September 5, she provided testimony to congressional committee hearings on stem cell research, pointing out that the use of Lupron in the process of creating embryos may cause "the very diseases that are being claimed as those diseases necessitating embryonic stem cell research for a cure." Millican finds it hard to swallow that the debate over stem cell research has totally ignored Lupron. Redflagsweekly January 25, 2002 Dr. Mercola's Comment: Folks, Lupron is a disaster drug that in no way shape or form treats the cause of the problem. I have seen it absolutely devastate many women's lives. It is one of the few drugs that I actually cringe when patients tell me that they have taken it. It is my experience and belief that this drug causes permanent neurological damage. This drug needs to be avoided at all costs. It is usually used for endometriosis, which is an estrogen dominance problem and is typically treated quite nicely with natural progesterone, a dietary program, and addressing the emotional stresses which cause the adrenal glands to become impaired Since the adrenals is the main biological of estrogen and progesterone, it is important to restore the proper functioning of this gland. One could take adrenal glandulars, or DHEA and pregnenolone, but those tend to be natural band-aids that don't address the reasons the adrenal became impaired. Answered by Latarsha Gharing 2 years ago.

I was one of the first guinea pigs to be prescribed Lupron for severe endometriosis in 1995. I had just undergone a laparoscopy and my ob-gyn insisted I try Lupron, especially, he said, because my husband and I had problems conceiving after one year of trying. The mood swings, migraines, dark, thick hair growth in weird places, hot flashes, and memory loss were only the beginning of the side effects I continue to have, 20 years later. I have not begun menopause, and the only baby that was conceived died in-utero at 16 weeks, and I never conceived again in my whole life. My endometriosis has gotten much worse, although I was diagnosed at stage 4 long ago, so I don t know what they would call the stage I have by now? 4+++? The pain has caused me to have to quit my dream job that I went to college for 7 years to work with children as a child psychologist, only to have my doctor reccomend I file for permanent disability because of the amount of pain medications I was taking to make it through the day, and the amount of memory loss I had incurred from Lupron. I have had hot flashes and mood swings for the past 20 years, so that now I need to take medication for PTSD for being attacked by a child at the school I worked with and my son I adopted when I was getting so sick and weak from the pain. I also have so many adhesions and scar tissue, it is really painful to eat a lot at once, because of the pain caused from intestinal blockages from the endometriosis. Please listen to those who have been on the medication and NOT your doctor!! YOu will also be at high risk for osteoporosis by the time you are 50, even if you are on Lupron for only 6 months. It is truly only a rotton bandaid that doctors get bonuses for and pharmaceutical companies get big bucks from the insurance at $2K per shot!! Don t do it! Answered by Marquita Pratte 2 years ago.

I agree stop taking this drug. I have done two years of research because the dr. keeps pushing it on me. I have continued to tell him no. there was one dr. that said if I don't take it he wouldn't treat me. I didn't have him treat me. Dr.'s are trying to find a way out of solving problems, and this is NOT it. I am still struggling with endo and PCS, but I would rather struggle without the side effects. Best of luck to you. I hope you feel better REALLY soon. Answered by Claudia Sams 2 years ago.

I have met women who did Lupron and then when they went off of it had issues with extreme fatigue such as due to Chronic Fatigue Syndrome and even fibromyalgia. I haven't met any as of yet that had issues with insomnia or nausea when coming off the medication though. Answered by Nikita Preyor 2 years ago.


Lupron Depot pros?
In the next few days I will be recieving the Lupron Depot shot (11.25mg). I am 20 years old and have been going through the painful effects of endometrosis for several years.I have read over alot of reviews from this shot and i'm seeing alot of negitive side effects. I get sick really easy so I'm afriad... Asked by Rueben Crute 2 years ago.

In the next few days I will be recieving the Lupron Depot shot (11.25mg). I am 20 years old and have been going through the painful effects of endometrosis for several years.I have read over alot of reviews from this shot and i'm seeing alot of negitive side effects. I get sick really easy so I'm afriad that my body will take this shot badly. I had a laproscopy in November of 2006 when I was finally diagnosed with the endo and where they burned out most of it. The next period I had was extreme pain as usual. The only pro that I see in getting this shot is the fact that I will be pain free for 6 months in the period department. I was wondering if there was anymore pros that anyone has experienced fromt his shot. Answered by Chase Slemmer 2 years ago.

No period for six months is about the only pro. I was in the same situation you are. I was diagnosed with endometriosis, and had been through three different pills, a laproscotomy/ DNC, then finally lupron. To be honest, I still experienced some pain while on the shot. The first month the pain was pretty much the same, because of the time it takes for the medicine to work through the body. After that, I didn't have the sharp stabbing pains, but just mild discomfort every once in a while. Expect when you get your shot for you muscles to tighten around the area that the shot was given. (Usually in the behind alternating cheeks each month.) I really didn't feel sick when I got my shot. However, once the medicine was in my body I had pretty much all the side effects of menopause. (After all, that is what you are putting your body through.) Things I experienced where; hot flashes, breast tenderness, dryness in the cervix, decrease in the sex drive, night sweats, and mood swings. Also, my first pap after the lupron course came back abnormal. I am not trying to get you to not have the course done, because it can be beneficial. However, there are many side effects and problems that can come with it. Answered by Nathalie Brozie 2 years ago.


Endometriosis and Lupron Depot?
P.S I really have had Endo symptoms since the onset of menses at age 10. I began taking the pill at 13 until I was 19, then became pregnant with my son. I'm now 34. The pill lessened my symptoms, but was still told it was in my head.I DID exercises, relaxation techniques, the WHOLE gammet. I always... Asked by Lakeshia Arciniega 2 years ago.

I have been taking Lupron Depot for 6 months now, and thinking about another 6 month cycle. I have suffered for 10+ years with endometriosis, and being pain free these last 6 months has been a BIG relief. OK, so I'm a little irritable and could care less about sex (me, who HAD to have it at least once a day, and what is an orgasam again?) I was just wondering if anyone out there has anything positive from their experience with this disease and the treatments available. I am still in child beraing age, and would like the possibility of having another child (even when I feel like wringing my 14 year old's neck...lol...) IS there life out there.... Answered by Martin Mcpartland 2 years ago.

Thanks for all your feedback. I actually have decided to not take the Lupron any more. I did have the surgery in July, and I think I'll take a bcp so I don't have a period for a while. After that who knows...maybe someone will figure out a cure for this dreadful diesase and we can all be pain free!!! LOL.... As far as bleeding with the Lupron, after the first month, I had no bleeding, except when I missed an appointment for a shot. Even 2 days late, and a little spotting, so don't miss your appointment. The only real side effects I have had is lack of sex drive and response as well as hot flashes...Take the add back therapy, that help balance my emotions as well as stop the flashes. GL all!!!! Thanks again for sharing Answered by Kristopher Wildes 2 years ago.

P.S I really have had Endo symptoms since the onset of menses at age 10. I began taking the pill at 13 until I was 19, then became pregnant with my son. I'm now 34. The pill lessened my symptoms, but was still told it was in my head. I DID exercises, relaxation techniques, the WHOLE gammet. I always felt as if I was a wimp, no one else cried like I did. And as I got older, Dr's told me the heavy flow was "normal"...What part of a box of pads a day and even several tampons is "normal"? I don't know... GL all, let's prey for a cure!!! Answered by Belinda Leamy 2 years ago.

Here's my story, I was diagnosed officially with endometriosis in 2003. I beleive I had it all along but it started to affect my daily life in 2001, during my pregnancy. I chased for two years for a diagnosis, I'm sure your familiar with the run around and hassles that go with that.. and finally got a doctor to do a diagnostic lap. so I got the lap. and sure enough it was what I had suspected all along--- Endo. She didn't treat it because she felt that doing so wouldn't do any good. and it's a good thing that she didnt because she definately wasn't qualified. (which I'll explain why in a moment) so now I had a diagnosis I did tons of research, spent countless hours on the internet reading through hundreds of research articles and personal experiences about endo. I talked with lots of endo sufferers and looked into all the options. My doctor put me on bcp's which I knew weren't going to do a thing (I was already on those and they didn't help) after reading up on the options I decided against lupron. Too many long term negatives for short term relief. But I knew I had to do something because I was surviving on vicodin and tylenol to get me out of bed and to help me go to sleep at night and that was beginning to fail me. I was a shell of the person I was before. I couldn't enjoy any of the things I used to. So, after all my research and talking with different people, I decided on excision, next I had to pick the surgeon. I chose someone who is known nationally and happened to be only 3 hours away. So I called and did a few consultations over the phone and decided to set up surgury with Dr. Cook. But I would have to wait 6 months before my insurance would pay any of it. So I decided to take seasonale during that time to try and help me cope in the meantime. It did help more than just regular bcp's and it was wonderful to only have a period every 4 months. Surgury was on september 9th 2004 and endo was removed from the sigmoid colon, both ureturs, pelvic wall, and a few various other places scattered in the pelvic area. There was actually endo and scar tissue wrapped around the sigmoid colon and adhering it to the pelvic wall. In my original diagnostic lap. my previous gyn had said that my right ovary was covered in scar tissue, when actually, both my ovaries were completely healthy no endo or scar tissue anywhere on them so if she had removed the endo from my "ovary" or tried to remove that "ovary" (which was actually my sigmoid colon)since it was so badly covered, she could have been trying to remove part of my bowels! Causing bowel contents to spill into the abdomen which may have killed me. But anyway, since the afternoon of september 9th 2004 (after my surgery) I have been free of endometriosis pain. this september will be 3 years and it has been wonderful. I was able to have another child and was able to return to the physically active life that I had before endo reared it's ugly head. So that's my story, I appologize for how long it is (and this is the condensed version!) but thanks for reading this far and I hope that it helps in some way. Answered by Cierra Chiarmonte 2 years ago.

I just started on the Lupron Depot 2 months ago. I have questions- how long did you have bleeding with the shot? My GYN says this is normal and can last for several months. At first mine was just spotting now it is like a normal period, minus the severe endo pain. I was diagnosed with Endometriosis in January after being told for more then a year that I had mental issues that was causing my severe pain each month. The docs exact words were that "all menstraul pain that women have are in their heads"! He finally agreed to a pelvic ultrasound and we found two masses on both my ovaries. He referred me then to a GYN. I've only seen her 3 times, once for a consult, then a laproscopy then for my Lupron. Then has been no follow up to see if the endo has stopped spreading or were else it is. Do you have leg pain from were they gave you the shot? My hip and leg hurt on the side I had the spot on. And do you have headaches? I have severe migraines almost every other day. I had migraines before but not this frequently. as for the side affects, so far it's just leg pain, headaches and the bleeding. My sex drive hasn't decreased, but I am moodier and have had a few hot flashes. Thanks for listening and hopefully answer my questions too. Sorry I couldn't anwer yours. Answered by Tangela Girsh 2 years ago.

I have been suffering from Endo for a LONG time. I was mis diagnosed with an ovarian cyst, appendicitis(which led to that being removed), and a turn muscle in my abdomen. It wasn't until Feb. of this year that i have actually been diagnosed with endo. I have heard way too many horror stories about people on Lupron. Way more negative stuff than positive. So, i decided to go all natural. No pain pills or injections or anything(while still under the safe supervision of my gyn). Deep tissue massage, acupuncture, and yoga have helped me significantly. These things take time to start working, so in the mean time i took a hot bath every night, drank hot tea, and practiced relaxation to help me get rid of the pain. I have run into skepticism about my way of dealing with the pain- but again- its my way. It may not work for you, but before you continue with a harsh chemical in your body- at least try going natural for a while. I also want to have children soon and i do not want to put anymore unnatural things into my body. Give it a try and you may be pleasantly surprised! Answered by Floy Battersby 2 years ago.


Lupron Depot---help!!!?
I have endometriosis. Last Thursday I received my second shot of Lupron Depot, and my gyn did some blood work to determine my estrogen levels because I had breakthrough bleeding that didn't end. It was just some dark brown discharge, but sometimes it would be tinged pink.So, my estrogen levels were... Asked by Elida Pluviose 2 years ago.

I have endometriosis. Last Thursday I received my second shot of Lupron Depot, and my gyn did some blood work to determine my estrogen levels because I had breakthrough bleeding that didn't end. It was just some dark brown discharge, but sometimes it would be tinged pink. So, my estrogen levels were determined to be a bit high, so three days ago I went back to get a tiny bit more Lupron in hopes of stopping the breakthrough bleeding. I noticed a change within just a few hours...the discharge had become much lighter in color. And throughout wednesday and thursday it remained lighter. Then this morning I noticed that it had gotten a bit darker, and just a few minutes ago I noticed a tiny bit of obviously red blood in my underpants. Should I be concerned? Should I tell my mom? I'm really nervous. Answered by Vanesa Corridoni 2 years ago.

I have taken lupron depot before too because I also have Endometriosis. Are you having bad pelvic cramping with the spotting? You should wear panti liners for the blood spotting. You have not been on Lupron very long and it takes awhile for your periods to stop. So you shouldn't be concerned over a little bit of spotting. But if you are getting severe cramping with it, then please tell your mom and call your doctor's office right away. Lupron has bad side effects that can make you sick, I believe nausea was one of the worst side effects. At some point you may not be able to take it anymore, when you can no longer tolerate the side effects. I feel so sorry for you honey, having Endometriosis. It is a lifetime of chronic pelvic pain. They can treat it, but they can NEVER make it go away. So eventually when you are older they'll want to remove your uterus to stop your periods. But before they do that, they want to give you the chance to have children later in Life if that is what you want. Because I've had this disease all of my Life, I really can sympathize with you. Best of luck! Answered by Rolland Tenharmsel 2 years ago.


Anyone else taken Lupron Depot?
I'm going to be going on this in a couple of weeks. I just wanted to know if anyone else has had experience with this. I've done the research, I know the side effects, but nothing else has worked for my endometriosis. I had surgery two months ago to have it removed and I'm going on Lupron so it... Asked by Marian Swagger 2 years ago.

I'm going to be going on this in a couple of weeks. I just wanted to know if anyone else has had experience with this. I've done the research, I know the side effects, but nothing else has worked for my endometriosis. I had surgery two months ago to have it removed and I'm going on Lupron so it won't come back. Answered by Ardath Grohmann 2 years ago.


Any thoughts on the lupron depot shots?
I'm 18 years old and was diagnosed and treated for stage three endo about 7 months ago and my symptoms are returning tenfold. I saw my OB/GYN today and she told me she was really concerned about this and told me my best course of treatment would be to have a second laproscopy and follow it directly with the... Asked by Takako Arizola 2 years ago.

I'm 18 years old and was diagnosed and treated for stage three endo about 7 months ago and my symptoms are returning tenfold. I saw my OB/GYN today and she told me she was really concerned about this and told me my best course of treatment would be to have a second laproscopy and follow it directly with the Lupron Depot shot for six months (one shot every three months). Does anyone have a success stoy? Or a horror story maybe? Please help!!! Answered by Edmundo Weil 2 years ago.

Dear Chickedee, I do NOT recommend Lupron Depot Injections to anyone, but for someone as young as you, I think your Doctor really needs to get on the web and do his/her homework. I was 38 when I received my one + only 3 month shot of Lupron. It did not help my pain at all - it actually caused many new pains. I went from being a firefighter/EMT to a woman who is now filing for disability due to the havoc Lupron created by shutting down my master gland. Google Lupron Victims and you will find a yahoo group that can direct you to a lupron research site, which has many links to news srories, court caseses, etc. Also, please always keep in mind that Lupron is not a cure! Your relief will be temporary, but there's a good chance your side effects will last a lifetime. Good luck! Answered by Delana Buther 2 years ago.


Lupron depot?
complcations with long use?i haveon this for almost 9 years Asked by Keila Tallman 2 years ago.

I was on it about 13 years ago. I didn't have any problems with it other than it shut down my cycles for those 6 months. You'll be fine. After those, you should consider Seasonale birth control. I've been on that for the last 2 years for my endometriosis. Before that I was on the depo provera shots for 9 years Answered by Gaylord Grissam 2 years ago.


Has anybody ever taken the lupron depot shot and what were the side effects?
would you recommend taking the injection to cure the endometriosis? Asked by Larry Touton 2 years ago.

I had 3 lupron depot before I couldnt stand them anymore. My pain got worse with the shots not better. Then there was the hot flashes and mood swings. I wouldnt recommend the shots but that was just experience it might work for you. Answered by Doretta Sleeth 2 years ago.

I tried it for two months and it did absolutely nothing except make me more miserable. A friend of mine had them for six months and she was worse off than me. I remember having hot flashes and night sweats that were far worse than actual menopause. The shot definitely did not cure my endometriosis. I ended up having a total hysterectomy which was far better than those awful shots. Maybe other people have had good results with Lupron but I did not. Good Luck!! Answered by Shamika Muskrat 2 years ago.


Lupron depot shot for women?
has anyone heard, or had the lupron depot shot for endometriosis and what were your or there expreince with it? i am about to get the shot and it last for 6 months Asked by Stephenie Geelan 2 years ago.

Lupron Depot Shot Answered by Jayson Wesselink 2 years ago.

HI, wife had it and it was the worst thing going. she gained a ton of weight and has never lost it. it basiclaly is putting you into menepause chemicaly induced for 6 months since the endo feeds off your estrogen. they put you in menepause so that you do not produce the estrogen, pregancy will do the same thing but you may not want to get prego now. The hormones really messed with her, she had bad diarea and her periods were all messed up for a long time after. And then the endo came right back. Then the doc suggested cutting the nerve to her uterus so at least she would not feel the pain, yeah thats a real cure doc. anyway- she found an applied kinesiaologist who worked with her on the endo and she has been clr ever since. Hope this has helped. email me if you want to chat more. trialtoid@yahoo.com Answered by Tennie Mentz 2 years ago.

I was on it about 13 years ago. I didn't have any problems with it other than it shut down my cycles for those 6 months. You'll be fine. After those, you should consider Seasonale birth control. I've been on that for the last 2 years for my endometriosis. Before that I was on the depo provera shots for 9 years Answered by Gloria Stotesberry 2 years ago.

I had the shot about 4 years ago. I did have some menopausal symptoms. The shot didn't work for me and I ended up having a hysterectomy about 6 months later. Answered by Felecia Bogany 2 years ago.

the doc wants me on it to, but it puts you threw menopause. you will get all the symptoms a 45 year old lady has. in tying to avoid this the doc but me on bc pills consistently all 30 days. to stop my peroid. Answered by Jeffery Wucherer 2 years ago.


What are your experiences with depot lupron?
I have had horrible side effects from the Depot Lupron shot (3-months doasage), now I am not talking about depot provera, this is a stronger shot to treat endometriosis. It has helped with the pain and lessened the growths, but I have bad hot flashes, weight gain, dryness, the list goes on. Anyone have better... Asked by Clarice Savely 2 years ago.

I have had horrible side effects from the Depot Lupron shot (3-months doasage), now I am not talking about depot provera, this is a stronger shot to treat endometriosis. It has helped with the pain and lessened the growths, but I have bad hot flashes, weight gain, dryness, the list goes on. Anyone have better experience with it? Can anyone suggest an alternative treatment?? BCPs don't work, i tried them already. Answered by Homer Shumake 2 years ago.

Stay FAR away from Lupron!!!!! Endo is an estrogen dominance disease. You need to replace the progesterone that your body is missing with a NATURAL PROGESTERONE CREAM! Email me and I can tell you more. This is some very nasty stuff. :( Here is an article I found.... Be Careful of Lupron for Endometriosis, It Could Be the Kiss of Death By Nicholas Regush This particular saga began a decade ago with an injection of a powerful prescription drug called Lupron. Lynne Millican took the shot for endometriosis, a condition in which pieces of the lining of the uterus are found in other parts of the body, especially in the pelvic cavity. Ten years later, Millican believes she is still suffering from the effects of that injection. Her many symptoms have included the development of a noncancerous tumor, breast cysts, cardiac arrythmias, dizziness, swelling and fatigue. Millican is a registered nurse (and paralegal) living in the Boston area who has become deeply involved in a grass-roots movement to force the U.S. Food and Drug Administration (FDA), and Members of Congress to take a close look at Lupron. The FDA first approved Lupron in 1985 for treatment of men with advanced prostate cancer, and then approved it for treatment of endometriosis in 1990 and uterine fibroids in 1995. "There are thousands in the United States who say they have been victimized by this drug," Millican said, emphasizing that symptoms can be severe, such as tremors, seizures and memory loss. "Many women I know say their symptoms didn't stop when they stopped taking the drug." The FDA has received a wide range of reports of serious side-effects, including death, suspected to be associated with the use of Lupron, but the agency, which holds that the drug's benefits outweigh the risks, does not believe there is sufficient proof to blame Lupron. TAP Pharmaceuticals Inc., jointly owned by Abbott Laboratories and Takeda Chemical Industries of Japan, has steadfastly maintained that Lupron is safe. Millican, who feels that the FDA has been very slow on the draw with Lupron, is also frustrated by the lack of response from almost all of the many senators and representatives in Congress to whom she has written. She has even submitted written testimony to various committee hearings - but to no avail. "It seems that no one but the people who suffer from Lupron are interested in looking into this drug," she said. Millican cannot even recall anyone with an MD degree who has voiced strong concern about Lupron. At the very least, she feels Lupron's safety should be an issue because doctors use it for purposes that were never approved by the FDA. While legal under federal law - once approved for an indication, a drug can be used for other purposes - unapproved use often occurs without the benefit of appropriate safety and efficacy studies. One of Millican's main concerns is Lupron's unapproved use in fertility clinics. The drug is essentially used to suppress female hormones which produce a mature egg. This allows fertility doctors to then induce "controlled" stimulation of multiple eggs. "I am concerned that women who undergo these procedures are not being sufficiently informed about Lupron's side-effects," Millican said. There is even much more at stake, according to Millican. On September 5, she provided testimony to congressional committee hearings on stem cell research, pointing out that the use of Lupron in the process of creating embryos may cause "the very diseases that are being claimed as those diseases necessitating embryonic stem cell research for a cure." Millican finds it hard to swallow that the debate over stem cell research has totally ignored Lupron. Redflagsweekly January 25, 2002 Dr. Mercola's Comment: Folks, Lupron is a disaster drug that in no way shape or form treats the cause of the problem. I have seen it absolutely devastate many women's lives. It is one of the few drugs that I actually cringe when patients tell me that they have taken it. It is my experience and belief that this drug causes permanent neurological damage. This drug needs to be avoided at all costs. It is usually used for endometriosis, which is an estrogen dominance problem and is typically treated quite nicely with natural progesterone, a dietary program, and addressing the emotional stresses which cause the adrenal glands to become impaired Since the adrenals is the main biological of estrogen and progesterone, it is important to restore the proper functioning of this gland. One could take adrenal glandulars, or DHEA and pregnenolone, but those tend to be natural band-aids that don't address the reasons the adrenal became impaired. Answered by Terrie Bhamaraniyama 2 years ago.

I was one of the first guinea pigs to be prescribed Lupron for severe endometriosis in 1995. I had just undergone a laparoscopy and my ob-gyn insisted I try Lupron, especially, he said, because my husband and I had problems conceiving after one year of trying. The mood swings, migraines, dark, thick hair growth in weird places, hot flashes, and memory loss were only the beginning of the side effects I continue to have, 20 years later. I have not begun menopause, and the only baby that was conceived died in-utero at 16 weeks, and I never conceived again in my whole life. My endometriosis has gotten much worse, although I was diagnosed at stage 4 long ago, so I don t know what they would call the stage I have by now? 4+++? The pain has caused me to have to quit my dream job that I went to college for 7 years to work with children as a child psychologist, only to have my doctor reccomend I file for permanent disability because of the amount of pain medications I was taking to make it through the day, and the amount of memory loss I had incurred from Lupron. I have had hot flashes and mood swings for the past 20 years, so that now I need to take medication for PTSD for being attacked by a child at the school I worked with and my son I adopted when I was getting so sick and weak from the pain. I also have so many adhesions and scar tissue, it is really painful to eat a lot at once, because of the pain caused from intestinal blockages from the endometriosis. Please listen to those who have been on the medication and NOT your doctor!! YOu will also be at high risk for osteoporosis by the time you are 50, even if you are on Lupron for only 6 months. It is truly only a rotton bandaid that doctors get bonuses for and pharmaceutical companies get big bucks from the insurance at $2K per shot!! Don t do it! Answered by Malorie Trippe 2 years ago.

I agree stop taking this drug. I have done two years of research because the dr. keeps pushing it on me. I have continued to tell him no. there was one dr. that said if I don't take it he wouldn't treat me. I didn't have him treat me. Dr.'s are trying to find a way out of solving problems, and this is NOT it. I am still struggling with endo and PCS, but I would rather struggle without the side effects. Best of luck to you. I hope you feel better REALLY soon. Answered by Deangelo Kastanes 2 years ago.

I have met women who did Lupron and then when they went off of it had issues with extreme fatigue such as due to Chronic Fatigue Syndrome and even fibromyalgia. I haven't met any as of yet that had issues with insomnia or nausea when coming off the medication though. Answered by Kris Swasey 2 years ago.


Lupron Depot pros?
In the next few days I will be recieving the Lupron Depot shot (11.25mg). I am 20 years old and have been going through the painful effects of endometrosis for several years.I have read over alot of reviews from this shot and i'm seeing alot of negitive side effects. I get sick really easy so I'm afriad... Asked by Rory Teteak 2 years ago.

In the next few days I will be recieving the Lupron Depot shot (11.25mg). I am 20 years old and have been going through the painful effects of endometrosis for several years.I have read over alot of reviews from this shot and i'm seeing alot of negitive side effects. I get sick really easy so I'm afriad that my body will take this shot badly. I had a laproscopy in November of 2006 when I was finally diagnosed with the endo and where they burned out most of it. The next period I had was extreme pain as usual. The only pro that I see in getting this shot is the fact that I will be pain free for 6 months in the period department. I was wondering if there was anymore pros that anyone has experienced fromt his shot. Answered by Myriam Caroway 2 years ago.

No period for six months is about the only pro. I was in the same situation you are. I was diagnosed with endometriosis, and had been through three different pills, a laproscotomy/ DNC, then finally lupron. To be honest, I still experienced some pain while on the shot. The first month the pain was pretty much the same, because of the time it takes for the medicine to work through the body. After that, I didn't have the sharp stabbing pains, but just mild discomfort every once in a while. Expect when you get your shot for you muscles to tighten around the area that the shot was given. (Usually in the behind alternating cheeks each month.) I really didn't feel sick when I got my shot. However, once the medicine was in my body I had pretty much all the side effects of menopause. (After all, that is what you are putting your body through.) Things I experienced where; hot flashes, breast tenderness, dryness in the cervix, decrease in the sex drive, night sweats, and mood swings. Also, my first pap after the lupron course came back abnormal. I am not trying to get you to not have the course done, because it can be beneficial. However, there are many side effects and problems that can come with it. Answered by Cordell Kicker 2 years ago.


Endometriosis and Lupron Depot?
P.S I really have had Endo symptoms since the onset of menses at age 10. I began taking the pill at 13 until I was 19, then became pregnant with my son. I'm now 34. The pill lessened my symptoms, but was still told it was in my head.I DID exercises, relaxation techniques, the WHOLE gammet. I always... Asked by Roman Micale 2 years ago.

I have been taking Lupron Depot for 6 months now, and thinking about another 6 month cycle. I have suffered for 10+ years with endometriosis, and being pain free these last 6 months has been a BIG relief. OK, so I'm a little irritable and could care less about sex (me, who HAD to have it at least once a day, and what is an orgasam again?) I was just wondering if anyone out there has anything positive from their experience with this disease and the treatments available. I am still in child beraing age, and would like the possibility of having another child (even when I feel like wringing my 14 year old's neck...lol...) IS there life out there.... Answered by Jerlene Sahlberg 2 years ago.

Thanks for all your feedback. I actually have decided to not take the Lupron any more. I did have the surgery in July, and I think I'll take a bcp so I don't have a period for a while. After that who knows...maybe someone will figure out a cure for this dreadful diesase and we can all be pain free!!! LOL.... As far as bleeding with the Lupron, after the first month, I had no bleeding, except when I missed an appointment for a shot. Even 2 days late, and a little spotting, so don't miss your appointment. The only real side effects I have had is lack of sex drive and response as well as hot flashes...Take the add back therapy, that help balance my emotions as well as stop the flashes. GL all!!!! Thanks again for sharing Answered by Jeff Chiavaroli 2 years ago.

P.S I really have had Endo symptoms since the onset of menses at age 10. I began taking the pill at 13 until I was 19, then became pregnant with my son. I'm now 34. The pill lessened my symptoms, but was still told it was in my head. I DID exercises, relaxation techniques, the WHOLE gammet. I always felt as if I was a wimp, no one else cried like I did. And as I got older, Dr's told me the heavy flow was "normal"...What part of a box of pads a day and even several tampons is "normal"? I don't know... GL all, let's prey for a cure!!! Answered by Eura Bertling 2 years ago.

Here's my story, I was diagnosed officially with endometriosis in 2003. I beleive I had it all along but it started to affect my daily life in 2001, during my pregnancy. I chased for two years for a diagnosis, I'm sure your familiar with the run around and hassles that go with that.. and finally got a doctor to do a diagnostic lap. so I got the lap. and sure enough it was what I had suspected all along--- Endo. She didn't treat it because she felt that doing so wouldn't do any good. and it's a good thing that she didnt because she definately wasn't qualified. (which I'll explain why in a moment) so now I had a diagnosis I did tons of research, spent countless hours on the internet reading through hundreds of research articles and personal experiences about endo. I talked with lots of endo sufferers and looked into all the options. My doctor put me on bcp's which I knew weren't going to do a thing (I was already on those and they didn't help) after reading up on the options I decided against lupron. Too many long term negatives for short term relief. But I knew I had to do something because I was surviving on vicodin and tylenol to get me out of bed and to help me go to sleep at night and that was beginning to fail me. I was a shell of the person I was before. I couldn't enjoy any of the things I used to. So, after all my research and talking with different people, I decided on excision, next I had to pick the surgeon. I chose someone who is known nationally and happened to be only 3 hours away. So I called and did a few consultations over the phone and decided to set up surgury with Dr. Cook. But I would have to wait 6 months before my insurance would pay any of it. So I decided to take seasonale during that time to try and help me cope in the meantime. It did help more than just regular bcp's and it was wonderful to only have a period every 4 months. Surgury was on september 9th 2004 and endo was removed from the sigmoid colon, both ureturs, pelvic wall, and a few various other places scattered in the pelvic area. There was actually endo and scar tissue wrapped around the sigmoid colon and adhering it to the pelvic wall. In my original diagnostic lap. my previous gyn had said that my right ovary was covered in scar tissue, when actually, both my ovaries were completely healthy no endo or scar tissue anywhere on them so if she had removed the endo from my "ovary" or tried to remove that "ovary" (which was actually my sigmoid colon)since it was so badly covered, she could have been trying to remove part of my bowels! Causing bowel contents to spill into the abdomen which may have killed me. But anyway, since the afternoon of september 9th 2004 (after my surgery) I have been free of endometriosis pain. this september will be 3 years and it has been wonderful. I was able to have another child and was able to return to the physically active life that I had before endo reared it's ugly head. So that's my story, I appologize for how long it is (and this is the condensed version!) but thanks for reading this far and I hope that it helps in some way. Answered by Albertina Petton 2 years ago.

I just started on the Lupron Depot 2 months ago. I have questions- how long did you have bleeding with the shot? My GYN says this is normal and can last for several months. At first mine was just spotting now it is like a normal period, minus the severe endo pain. I was diagnosed with Endometriosis in January after being told for more then a year that I had mental issues that was causing my severe pain each month. The docs exact words were that "all menstraul pain that women have are in their heads"! He finally agreed to a pelvic ultrasound and we found two masses on both my ovaries. He referred me then to a GYN. I've only seen her 3 times, once for a consult, then a laproscopy then for my Lupron. Then has been no follow up to see if the endo has stopped spreading or were else it is. Do you have leg pain from were they gave you the shot? My hip and leg hurt on the side I had the spot on. And do you have headaches? I have severe migraines almost every other day. I had migraines before but not this frequently. as for the side affects, so far it's just leg pain, headaches and the bleeding. My sex drive hasn't decreased, but I am moodier and have had a few hot flashes. Thanks for listening and hopefully answer my questions too. Sorry I couldn't anwer yours. Answered by Gia Trichel 2 years ago.

I have been suffering from Endo for a LONG time. I was mis diagnosed with an ovarian cyst, appendicitis(which led to that being removed), and a turn muscle in my abdomen. It wasn't until Feb. of this year that i have actually been diagnosed with endo. I have heard way too many horror stories about people on Lupron. Way more negative stuff than positive. So, i decided to go all natural. No pain pills or injections or anything(while still under the safe supervision of my gyn). Deep tissue massage, acupuncture, and yoga have helped me significantly. These things take time to start working, so in the mean time i took a hot bath every night, drank hot tea, and practiced relaxation to help me get rid of the pain. I have run into skepticism about my way of dealing with the pain- but again- its my way. It may not work for you, but before you continue with a harsh chemical in your body- at least try going natural for a while. I also want to have children soon and i do not want to put anymore unnatural things into my body. Give it a try and you may be pleasantly surprised! Answered by Lou Jamie 2 years ago.


Lupron Depot---help!!!?
I have endometriosis. Last Thursday I received my second shot of Lupron Depot, and my gyn did some blood work to determine my estrogen levels because I had breakthrough bleeding that didn't end. It was just some dark brown discharge, but sometimes it would be tinged pink.So, my estrogen levels were... Asked by Alejandra Fischang 2 years ago.

I have endometriosis. Last Thursday I received my second shot of Lupron Depot, and my gyn did some blood work to determine my estrogen levels because I had breakthrough bleeding that didn't end. It was just some dark brown discharge, but sometimes it would be tinged pink. So, my estrogen levels were determined to be a bit high, so three days ago I went back to get a tiny bit more Lupron in hopes of stopping the breakthrough bleeding. I noticed a change within just a few hours...the discharge had become much lighter in color. And throughout wednesday and thursday it remained lighter. Then this morning I noticed that it had gotten a bit darker, and just a few minutes ago I noticed a tiny bit of obviously red blood in my underpants. Should I be concerned? Should I tell my mom? I'm really nervous. Answered by Lucia Freidman 2 years ago.

I have taken lupron depot before too because I also have Endometriosis. Are you having bad pelvic cramping with the spotting? You should wear panti liners for the blood spotting. You have not been on Lupron very long and it takes awhile for your periods to stop. So you shouldn't be concerned over a little bit of spotting. But if you are getting severe cramping with it, then please tell your mom and call your doctor's office right away. Lupron has bad side effects that can make you sick, I believe nausea was one of the worst side effects. At some point you may not be able to take it anymore, when you can no longer tolerate the side effects. I feel so sorry for you honey, having Endometriosis. It is a lifetime of chronic pelvic pain. They can treat it, but they can NEVER make it go away. So eventually when you are older they'll want to remove your uterus to stop your periods. But before they do that, they want to give you the chance to have children later in Life if that is what you want. Because I've had this disease all of my Life, I really can sympathize with you. Best of luck! Answered by Ebony Kurtulus 2 years ago.


Anyone else taken Lupron Depot?
I'm going to be going on this in a couple of weeks. I just wanted to know if anyone else has had experience with this. I've done the research, I know the side effects, but nothing else has worked for my endometriosis. I had surgery two months ago to have it removed and I'm going on Lupron so it... Asked by Rosenda Ciesluk 2 years ago.

I'm going to be going on this in a couple of weeks. I just wanted to know if anyone else has had experience with this. I've done the research, I know the side effects, but nothing else has worked for my endometriosis. I had surgery two months ago to have it removed and I'm going on Lupron so it won't come back. Answered by Pearlie Rasnake 2 years ago.


Any thoughts on the lupron depot shots?
I'm 18 years old and was diagnosed and treated for stage three endo about 7 months ago and my symptoms are returning tenfold. I saw my OB/GYN today and she told me she was really concerned about this and told me my best course of treatment would be to have a second laproscopy and follow it directly with the... Asked by Katlyn Smelser 2 years ago.

I'm 18 years old and was diagnosed and treated for stage three endo about 7 months ago and my symptoms are returning tenfold. I saw my OB/GYN today and she told me she was really concerned about this and told me my best course of treatment would be to have a second laproscopy and follow it directly with the Lupron Depot shot for six months (one shot every three months). Does anyone have a success stoy? Or a horror story maybe? Please help!!! Answered by Milda Knightly 2 years ago.

Dear Chickedee, I do NOT recommend Lupron Depot Injections to anyone, but for someone as young as you, I think your Doctor really needs to get on the web and do his/her homework. I was 38 when I received my one + only 3 month shot of Lupron. It did not help my pain at all - it actually caused many new pains. I went from being a firefighter/EMT to a woman who is now filing for disability due to the havoc Lupron created by shutting down my master gland. Google Lupron Victims and you will find a yahoo group that can direct you to a lupron research site, which has many links to news srories, court caseses, etc. Also, please always keep in mind that Lupron is not a cure! Your relief will be temporary, but there's a good chance your side effects will last a lifetime. Good luck! Answered by Marhta Kromer 2 years ago.


Lupron depot?
complcations with long use?i haveon this for almost 9 years Asked by Oretha Vailes 2 years ago.

I was on it about 13 years ago. I didn't have any problems with it other than it shut down my cycles for those 6 months. You'll be fine. After those, you should consider Seasonale birth control. I've been on that for the last 2 years for my endometriosis. Before that I was on the depo provera shots for 9 years Answered by Queen Ludovico 2 years ago.


Has anybody ever taken the lupron depot shot and what were the side effects?
would you recommend taking the injection to cure the endometriosis? Asked by Karol Stoodley 2 years ago.

I had 3 lupron depot before I couldnt stand them anymore. My pain got worse with the shots not better. Then there was the hot flashes and mood swings. I wouldnt recommend the shots but that was just experience it might work for you. Answered by Rob Boney 2 years ago.

I tried it for two months and it did absolutely nothing except make me more miserable. A friend of mine had them for six months and she was worse off than me. I remember having hot flashes and night sweats that were far worse than actual menopause. The shot definitely did not cure my endometriosis. I ended up having a total hysterectomy which was far better than those awful shots. Maybe other people have had good results with Lupron but I did not. Good Luck!! Answered by Estrella Schuur 2 years ago.


Lupron depot shot for women?
has anyone heard, or had the lupron depot shot for endometriosis and what were your or there expreince with it? i am about to get the shot and it last for 6 months Asked by Adele Kasparek 2 years ago.

Lupron Depot Shot Answered by Amelia Schladweiler 2 years ago.

HI, wife had it and it was the worst thing going. she gained a ton of weight and has never lost it. it basiclaly is putting you into menepause chemicaly induced for 6 months since the endo feeds off your estrogen. they put you in menepause so that you do not produce the estrogen, pregancy will do the same thing but you may not want to get prego now. The hormones really messed with her, she had bad diarea and her periods were all messed up for a long time after. And then the endo came right back. Then the doc suggested cutting the nerve to her uterus so at least she would not feel the pain, yeah thats a real cure doc. anyway- she found an applied kinesiaologist who worked with her on the endo and she has been clr ever since. Hope this has helped. email me if you want to chat more. trialtoid@yahoo.com Answered by Shannon Larotta 2 years ago.

I was on it about 13 years ago. I didn't have any problems with it other than it shut down my cycles for those 6 months. You'll be fine. After those, you should consider Seasonale birth control. I've been on that for the last 2 years for my endometriosis. Before that I was on the depo provera shots for 9 years Answered by Lucila Mcaveney 2 years ago.

I had the shot about 4 years ago. I did have some menopausal symptoms. The shot didn't work for me and I ended up having a hysterectomy about 6 months later. Answered by Belle Taranto 2 years ago.

the doc wants me on it to, but it puts you threw menopause. you will get all the symptoms a 45 year old lady has. in tying to avoid this the doc but me on bc pills consistently all 30 days. to stop my peroid. Answered by Alfredo Penner 2 years ago.


What are your experiences with depot lupron?
I have had horrible side effects from the Depot Lupron shot (3-months doasage), now I am not talking about depot provera, this is a stronger shot to treat endometriosis. It has helped with the pain and lessened the growths, but I have bad hot flashes, weight gain, dryness, the list goes on. Anyone have better... Asked by Jana Neufville 2 years ago.

I have had horrible side effects from the Depot Lupron shot (3-months doasage), now I am not talking about depot provera, this is a stronger shot to treat endometriosis. It has helped with the pain and lessened the growths, but I have bad hot flashes, weight gain, dryness, the list goes on. Anyone have better experience with it? Can anyone suggest an alternative treatment?? BCPs don't work, i tried them already. Answered by Rochell Crace 2 years ago.

Stay FAR away from Lupron!!!!! Endo is an estrogen dominance disease. You need to replace the progesterone that your body is missing with a NATURAL PROGESTERONE CREAM! Email me and I can tell you more. This is some very nasty stuff. :( Here is an article I found.... Be Careful of Lupron for Endometriosis, It Could Be the Kiss of Death By Nicholas Regush This particular saga began a decade ago with an injection of a powerful prescription drug called Lupron. Lynne Millican took the shot for endometriosis, a condition in which pieces of the lining of the uterus are found in other parts of the body, especially in the pelvic cavity. Ten years later, Millican believes she is still suffering from the effects of that injection. Her many symptoms have included the development of a noncancerous tumor, breast cysts, cardiac arrythmias, dizziness, swelling and fatigue. Millican is a registered nurse (and paralegal) living in the Boston area who has become deeply involved in a grass-roots movement to force the U.S. Food and Drug Administration (FDA), and Members of Congress to take a close look at Lupron. The FDA first approved Lupron in 1985 for treatment of men with advanced prostate cancer, and then approved it for treatment of endometriosis in 1990 and uterine fibroids in 1995. "There are thousands in the United States who say they have been victimized by this drug," Millican said, emphasizing that symptoms can be severe, such as tremors, seizures and memory loss. "Many women I know say their symptoms didn't stop when they stopped taking the drug." The FDA has received a wide range of reports of serious side-effects, including death, suspected to be associated with the use of Lupron, but the agency, which holds that the drug's benefits outweigh the risks, does not believe there is sufficient proof to blame Lupron. TAP Pharmaceuticals Inc., jointly owned by Abbott Laboratories and Takeda Chemical Industries of Japan, has steadfastly maintained that Lupron is safe. Millican, who feels that the FDA has been very slow on the draw with Lupron, is also frustrated by the lack of response from almost all of the many senators and representatives in Congress to whom she has written. She has even submitted written testimony to various committee hearings - but to no avail. "It seems that no one but the people who suffer from Lupron are interested in looking into this drug," she said. Millican cannot even recall anyone with an MD degree who has voiced strong concern about Lupron. At the very least, she feels Lupron's safety should be an issue because doctors use it for purposes that were never approved by the FDA. While legal under federal law - once approved for an indication, a drug can be used for other purposes - unapproved use often occurs without the benefit of appropriate safety and efficacy studies. One of Millican's main concerns is Lupron's unapproved use in fertility clinics. The drug is essentially used to suppress female hormones which produce a mature egg. This allows fertility doctors to then induce "controlled" stimulation of multiple eggs. "I am concerned that women who undergo these procedures are not being sufficiently informed about Lupron's side-effects," Millican said. There is even much more at stake, according to Millican. On September 5, she provided testimony to congressional committee hearings on stem cell research, pointing out that the use of Lupron in the process of creating embryos may cause "the very diseases that are being claimed as those diseases necessitating embryonic stem cell research for a cure." Millican finds it hard to swallow that the debate over stem cell research has totally ignored Lupron. Redflagsweekly January 25, 2002 Dr. Mercola's Comment: Folks, Lupron is a disaster drug that in no way shape or form treats the cause of the problem. I have seen it absolutely devastate many women's lives. It is one of the few drugs that I actually cringe when patients tell me that they have taken it. It is my experience and belief that this drug causes permanent neurological damage. This drug needs to be avoided at all costs. It is usually used for endometriosis, which is an estrogen dominance problem and is typically treated quite nicely with natural progesterone, a dietary program, and addressing the emotional stresses which cause the adrenal glands to become impaired Since the adrenals is the main biological of estrogen and progesterone, it is important to restore the proper functioning of this gland. One could take adrenal glandulars, or DHEA and pregnenolone, but those tend to be natural band-aids that don't address the reasons the adrenal became impaired. Answered by Eldon Wissinger 2 years ago.

I was one of the first guinea pigs to be prescribed Lupron for severe endometriosis in 1995. I had just undergone a laparoscopy and my ob-gyn insisted I try Lupron, especially, he said, because my husband and I had problems conceiving after one year of trying. The mood swings, migraines, dark, thick hair growth in weird places, hot flashes, and memory loss were only the beginning of the side effects I continue to have, 20 years later. I have not begun menopause, and the only baby that was conceived died in-utero at 16 weeks, and I never conceived again in my whole life. My endometriosis has gotten much worse, although I was diagnosed at stage 4 long ago, so I don t know what they would call the stage I have by now? 4+++? The pain has caused me to have to quit my dream job that I went to college for 7 years to work with children as a child psychologist, only to have my doctor reccomend I file for permanent disability because of the amount of pain medications I was taking to make it through the day, and the amount of memory loss I had incurred from Lupron. I have had hot flashes and mood swings for the past 20 years, so that now I need to take medication for PTSD for being attacked by a child at the school I worked with and my son I adopted when I was getting so sick and weak from the pain. I also have so many adhesions and scar tissue, it is really painful to eat a lot at once, because of the pain caused from intestinal blockages from the endometriosis. Please listen to those who have been on the medication and NOT your doctor!! YOu will also be at high risk for osteoporosis by the time you are 50, even if you are on Lupron for only 6 months. It is truly only a rotton bandaid that doctors get bonuses for and pharmaceutical companies get big bucks from the insurance at $2K per shot!! Don t do it! Answered by Clemencia Fassett 2 years ago.

I agree stop taking this drug. I have done two years of research because the dr. keeps pushing it on me. I have continued to tell him no. there was one dr. that said if I don't take it he wouldn't treat me. I didn't have him treat me. Dr.'s are trying to find a way out of solving problems, and this is NOT it. I am still struggling with endo and PCS, but I would rather struggle without the side effects. Best of luck to you. I hope you feel better REALLY soon. Answered by Collette Rozzi 2 years ago.

I have met women who did Lupron and then when they went off of it had issues with extreme fatigue such as due to Chronic Fatigue Syndrome and even fibromyalgia. I haven't met any as of yet that had issues with insomnia or nausea when coming off the medication though. Answered by Marylynn Schwandt 2 years ago.


Lupron Depot pros?
In the next few days I will be recieving the Lupron Depot shot (11.25mg). I am 20 years old and have been going through the painful effects of endometrosis for several years.I have read over alot of reviews from this shot and i'm seeing alot of negitive side effects. I get sick really easy so I'm afriad... Asked by Mark Gouldie 2 years ago.

In the next few days I will be recieving the Lupron Depot shot (11.25mg). I am 20 years old and have been going through the painful effects of endometrosis for several years.I have read over alot of reviews from this shot and i'm seeing alot of negitive side effects. I get sick really easy so I'm afriad that my body will take this shot badly. I had a laproscopy in November of 2006 when I was finally diagnosed with the endo and where they burned out most of it. The next period I had was extreme pain as usual. The only pro that I see in getting this shot is the fact that I will be pain free for 6 months in the period department. I was wondering if there was anymore pros that anyone has experienced fromt his shot. Answered by Page Dosh 2 years ago.

No period for six months is about the only pro. I was in the same situation you are. I was diagnosed with endometriosis, and had been through three different pills, a laproscotomy/ DNC, then finally lupron. To be honest, I still experienced some pain while on the shot. The first month the pain was pretty much the same, because of the time it takes for the medicine to work through the body. After that, I didn't have the sharp stabbing pains, but just mild discomfort every once in a while. Expect when you get your shot for you muscles to tighten around the area that the shot was given. (Usually in the behind alternating cheeks each month.) I really didn't feel sick when I got my shot. However, once the medicine was in my body I had pretty much all the side effects of menopause. (After all, that is what you are putting your body through.) Things I experienced where; hot flashes, breast tenderness, dryness in the cervix, decrease in the sex drive, night sweats, and mood swings. Also, my first pap after the lupron course came back abnormal. I am not trying to get you to not have the course done, because it can be beneficial. However, there are many side effects and problems that can come with it. Answered by Georgianne Gelber 2 years ago.


Endometriosis and Lupron Depot?
P.S I really have had Endo symptoms since the onset of menses at age 10. I began taking the pill at 13 until I was 19, then became pregnant with my son. I'm now 34. The pill lessened my symptoms, but was still told it was in my head.I DID exercises, relaxation techniques, the WHOLE gammet. I always... Asked by Booker Spindler 2 years ago.

I have been taking Lupron Depot for 6 months now, and thinking about another 6 month cycle. I have suffered for 10+ years with endometriosis, and being pain free these last 6 months has been a BIG relief. OK, so I'm a little irritable and could care less about sex (me, who HAD to have it at least once a day, and what is an orgasam again?) I was just wondering if anyone out there has anything positive from their experience with this disease and the treatments available. I am still in child beraing age, and would like the possibility of having another child (even when I feel like wringing my 14 year old's neck...lol...) IS there life out there.... Answered by Weston Grboyan 2 years ago.

Thanks for all your feedback. I actually have decided to not take the Lupron any more. I did have the surgery in July, and I think I'll take a bcp so I don't have a period for a while. After that who knows...maybe someone will figure out a cure for this dreadful diesase and we can all be pain free!!! LOL.... As far as bleeding with the Lupron, after the first month, I had no bleeding, except when I missed an appointment for a shot. Even 2 days late, and a little spotting, so don't miss your appointment. The only real side effects I have had is lack of sex drive and response as well as hot flashes...Take the add back therapy, that help balance my emotions as well as stop the flashes. GL all!!!! Thanks again for sharing Answered by Sharlene Caroselli 2 years ago.

P.S I really have had Endo symptoms since the onset of menses at age 10. I began taking the pill at 13 until I was 19, then became pregnant with my son. I'm now 34. The pill lessened my symptoms, but was still told it was in my head. I DID exercises, relaxation techniques, the WHOLE gammet. I always felt as if I was a wimp, no one else cried like I did. And as I got older, Dr's told me the heavy flow was "normal"...What part of a box of pads a day and even several tampons is "normal"? I don't know... GL all, let's prey for a cure!!! Answered by Mario Htwe 2 years ago.

Here's my story, I was diagnosed officially with endometriosis in 2003. I beleive I had it all along but it started to affect my daily life in 2001, during my pregnancy. I chased for two years for a diagnosis, I'm sure your familiar with the run around and hassles that go with that.. and finally got a doctor to do a diagnostic lap. so I got the lap. and sure enough it was what I had suspected all along--- Endo. She didn't treat it because she felt that doing so wouldn't do any good. and it's a good thing that she didnt because she definately wasn't qualified. (which I'll explain why in a moment) so now I had a diagnosis I did tons of research, spent countless hours on the internet reading through hundreds of research articles and personal experiences about endo. I talked with lots of endo sufferers and looked into all the options. My doctor put me on bcp's which I knew weren't going to do a thing (I was already on those and they didn't help) after reading up on the options I decided against lupron. Too many long term negatives for short term relief. But I knew I had to do something because I was surviving on vicodin and tylenol to get me out of bed and to help me go to sleep at night and that was beginning to fail me. I was a shell of the person I was before. I couldn't enjoy any of the things I used to. So, after all my research and talking with different people, I decided on excision, next I had to pick the surgeon. I chose someone who is known nationally and happened to be only 3 hours away. So I called and did a few consultations over the phone and decided to set up surgury with Dr. Cook. But I would have to wait 6 months before my insurance would pay any of it. So I decided to take seasonale during that time to try and help me cope in the meantime. It did help more than just regular bcp's and it was wonderful to only have a period every 4 months. Surgury was on september 9th 2004 and endo was removed from the sigmoid colon, both ureturs, pelvic wall, and a few various other places scattered in the pelvic area. There was actually endo and scar tissue wrapped around the sigmoid colon and adhering it to the pelvic wall. In my original diagnostic lap. my previous gyn had said that my right ovary was covered in scar tissue, when actually, both my ovaries were completely healthy no endo or scar tissue anywhere on them so if she had removed the endo from my "ovary" or tried to remove that "ovary" (which was actually my sigmoid colon)since it was so badly covered, she could have been trying to remove part of my bowels! Causing bowel contents to spill into the abdomen which may have killed me. But anyway, since the afternoon of september 9th 2004 (after my surgery) I have been free of endometriosis pain. this september will be 3 years and it has been wonderful. I was able to have another child and was able to return to the physically active life that I had before endo reared it's ugly head. So that's my story, I appologize for how long it is (and this is the condensed version!) but thanks for reading this far and I hope that it helps in some way. Answered by Ladonna Mcraney 2 years ago.

I just started on the Lupron Depot 2 months ago. I have questions- how long did you have bleeding with the shot? My GYN says this is normal and can last for several months. At first mine was just spotting now it is like a normal period, minus the severe endo pain. I was diagnosed with Endometriosis in January after being told for more then a year that I had mental issues that was causing my severe pain each month. The docs exact words were that "all menstraul pain that women have are in their heads"! He finally agreed to a pelvic ultrasound and we found two masses on both my ovaries. He referred me then to a GYN. I've only seen her 3 times, once for a consult, then a laproscopy then for my Lupron. Then has been no follow up to see if the endo has stopped spreading or were else it is. Do you have leg pain from were they gave you the shot? My hip and leg hurt on the side I had the spot on. And do you have headaches? I have severe migraines almost every other day. I had migraines before but not this frequently. as for the side affects, so far it's just leg pain, headaches and the bleeding. My sex drive hasn't decreased, but I am moodier and have had a few hot flashes. Thanks for listening and hopefully answer my questions too. Sorry I couldn't anwer yours. Answered by Darrel Sagraves 2 years ago.

I have been suffering from Endo for a LONG time. I was mis diagnosed with an ovarian cyst, appendicitis(which led to that being removed), and a turn muscle in my abdomen. It wasn't until Feb. of this year that i have actually been diagnosed with endo. I have heard way too many horror stories about people on Lupron. Way more negative stuff than positive. So, i decided to go all natural. No pain pills or injections or anything(while still under the safe supervision of my gyn). Deep tissue massage, acupuncture, and yoga have helped me significantly. These things take time to start working, so in the mean time i took a hot bath every night, drank hot tea, and practiced relaxation to help me get rid of the pain. I have run into skepticism about my way of dealing with the pain- but again- its my way. It may not work for you, but before you continue with a harsh chemical in your body- at least try going natural for a while. I also want to have children soon and i do not want to put anymore unnatural things into my body. Give it a try and you may be pleasantly surprised! Answered by Priscilla Jakab 2 years ago.


Lupron Depot---help!!!?
I have endometriosis. Last Thursday I received my second shot of Lupron Depot, and my gyn did some blood work to determine my estrogen levels because I had breakthrough bleeding that didn't end. It was just some dark brown discharge, but sometimes it would be tinged pink.So, my estrogen levels were... Asked by Mayola Mcclerkin 2 years ago.

I have endometriosis. Last Thursday I received my second shot of Lupron Depot, and my gyn did some blood work to determine my estrogen levels because I had breakthrough bleeding that didn't end. It was just some dark brown discharge, but sometimes it would be tinged pink. So, my estrogen levels were determined to be a bit high, so three days ago I went back to get a tiny bit more Lupron in hopes of stopping the breakthrough bleeding. I noticed a change within just a few hours...the discharge had become much lighter in color. And throughout wednesday and thursday it remained lighter. Then this morning I noticed that it had gotten a bit darker, and just a few minutes ago I noticed a tiny bit of obviously red blood in my underpants. Should I be concerned? Should I tell my mom? I'm really nervous. Answered by Tyesha Mcnab 2 years ago.

I have taken lupron depot before too because I also have Endometriosis. Are you having bad pelvic cramping with the spotting? You should wear panti liners for the blood spotting. You have not been on Lupron very long and it takes awhile for your periods to stop. So you shouldn't be concerned over a little bit of spotting. But if you are getting severe cramping with it, then please tell your mom and call your doctor's office right away. Lupron has bad side effects that can make you sick, I believe nausea was one of the worst side effects. At some point you may not be able to take it anymore, when you can no longer tolerate the side effects. I feel so sorry for you honey, having Endometriosis. It is a lifetime of chronic pelvic pain. They can treat it, but they can NEVER make it go away. So eventually when you are older they'll want to remove your uterus to stop your periods. But before they do that, they want to give you the chance to have children later in Life if that is what you want. Because I've had this disease all of my Life, I really can sympathize with you. Best of luck! Answered by Grayce Velardo 2 years ago.


Anyone else taken Lupron Depot?
I'm going to be going on this in a couple of weeks. I just wanted to know if anyone else has had experience with this. I've done the research, I know the side effects, but nothing else has worked for my endometriosis. I had surgery two months ago to have it removed and I'm going on Lupron so it... Asked by Berenice Hinzman 2 years ago.

I'm going to be going on this in a couple of weeks. I just wanted to know if anyone else has had experience with this. I've done the research, I know the side effects, but nothing else has worked for my endometriosis. I had surgery two months ago to have it removed and I'm going on Lupron so it won't come back. Answered by Marty Maisey 2 years ago.


Any thoughts on the lupron depot shots?
I'm 18 years old and was diagnosed and treated for stage three endo about 7 months ago and my symptoms are returning tenfold. I saw my OB/GYN today and she told me she was really concerned about this and told me my best course of treatment would be to have a second laproscopy and follow it directly with the... Asked by Clark Sapia 2 years ago.

I'm 18 years old and was diagnosed and treated for stage three endo about 7 months ago and my symptoms are returning tenfold. I saw my OB/GYN today and she told me she was really concerned about this and told me my best course of treatment would be to have a second laproscopy and follow it directly with the Lupron Depot shot for six months (one shot every three months). Does anyone have a success stoy? Or a horror story maybe? Please help!!! Answered by Nanci Bagge 2 years ago.

Dear Chickedee, I do NOT recommend Lupron Depot Injections to anyone, but for someone as young as you, I think your Doctor really needs to get on the web and do his/her homework. I was 38 when I received my one + only 3 month shot of Lupron. It did not help my pain at all - it actually caused many new pains. I went from being a firefighter/EMT to a woman who is now filing for disability due to the havoc Lupron created by shutting down my master gland. Google Lupron Victims and you will find a yahoo group that can direct you to a lupron research site, which has many links to news srories, court caseses, etc. Also, please always keep in mind that Lupron is not a cure! Your relief will be temporary, but there's a good chance your side effects will last a lifetime. Good luck! Answered by Essie Maselli 2 years ago.


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