Application Information

This drug has been submitted to the FDA under the reference 018771/001.

Names and composition

"LACRISERT" is the commercial name of a drug composed of HYDROXYPROPYL CELLULOSE.


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Answered questions

Roles of some of the ingredients used in a shampoo?
-) What are the roles of the following ingredients in a shampoo? Mg Silicate Al Silicate HPC (Hydroxypropylecellulose -) Another name for Al silicate and Mg silicate? Appreciate your help! Asked by Cathi Haeder 2 years ago.

(HPC) is a derivative of cellulose with both water solubility and organic solubility.Lacrisert, manufactured by Aton Pharma, is a formulation of HPC used for artificial tears. It is used to treat medical conditions characterized by insufficient tear production such as keratoconjunctivitis sicca), recurrent corneal erosions, decreased corneal sensitivity, exposure and neuroparalytic keratitis. HPC is also used as a lubricant for artificial eyes. As a food additive, HPC is used as a thickener, a low level binder and as an emulsion stabiliser with E number E463. In pharmaceuticals it is used as a disintegrant,[1] and a binder,[2] in tablets. HPC is used as a sieving matrix for DNA separations by capillary and microchip electrophoresis.[3] HPC is the main ingredient in Cellugel which is used in book conservation. Cellugel is described as "A safe, penetrating consolidant for leather book covers affected by red rot" and is produced by Preservation Solutions. So in shampoo it is a thickener and binder. Answered by Quiana Sieg 2 years ago.

How can you Recover/Cure Sjogren's Syndrome ???
How can you cure or recover Sjogren's syndrome ?? Asked by Johnny Witthuhn 2 years ago.

Sjögren's syndrome is a chronic, probably autoimmune, systemic inflammatory disorder of unknown cause characterized by dryness of the mouth, eyes, and other mucous membranes. It can be primary or secondary to other autoimmune disorders. Sjögren's syndrome may also cause rheumatoid-like arthritis or affect various exocrine glands or other organs. Diagnosis is by specific criteria relating to eye, mouth, and salivary gland involvement, autoantibodies, and histopathology. Treatment is symptomatic. SELF-CARE:- Many symptoms of Sjogren's syndrome respond well to self-care. A self-care plan may mean you follow some of the following advice: * Use artificial tears and eyedrops. These can relieve the discomfort of dry eyes. Artificial tears and eyedrops are available by prescription or over-the-counter. Thicker drops are available that you don't have to apply as often as other drops, but they may cause visual blurring and collect along your eyelashes. Ask your doctor about whether you should select artificial tears with or without preservatives, because the preservatives used to prolong the shelf life of some products can cause eye irritation in some people. Another treatment that can keep your eyes moist is small pellets of hydroxypropyl cellulose (Lacrisert), which are placed in your lower eyelid. When you add artificial tears, the pellets dissolve and form a film over the moisture. * Increase your fluid intake. Drinking lots of fluids, particularly water, helps to reduce dry mouth. Lemon juice in water may help stimulate salivary flow. Sugarless gum or hard candies also may help. Because the risk of dental cavities increases with Sjogren's syndrome, reduce your overall sugar intake, especially between meals. * Use moisturizers. If dry skin is a problem, avoid using very hot water to wash and avoid soaking your hands in water or cleaning solutions. Pat your skin — don't rub — with a towel and apply moisturizers when your skin is still damp. Use rubber gloves when doing dishes or housecleaning. Vaginal moisturizers and lubricants help women who experience vaginal dryness. * Stop smoking. Avoid smoking or exposure to secondhand smoke because smoke can increase your dryness. * Increase humidity. Increasing the indoor humidity or protecting yourself in windy environments may help you reduce dryness. For example, avoid sitting in front of a fan or air-conditioning vent. You may also want to use goggles or protective eyewear when you go outdoors. * Use nasal saline sprays. Nasal saline sprays can help moisturize dry nasal passages and may help relieve a dry mouth because a dry nose can increase mouth breathing. * Protect your oral health. Brush your teeth after every meal and schedule regular dental appointments to protect against the increased risk of dental cavities. Your dentist or doctor may also tell you to use daily topical fluoride treatments and antimicrobial mouthwashes. Artificial saliva products can help keep your mouth feeling moist. These products can also help to prevent cavities if they contain fluoride. If you develop an oral yeast infection (such as candidiasis), your doctor may prescribe antifungal lozenges — for example, clotrimazole (Mycelex) — that will slowly dissolve in your mouth. Antifungal medication is also available in liquid form, such as nystatin (Mycostatin), for you to swish around your mouth. Inflammation of the parotid gland (parotitis) can be helped by massage, the use of warm compresses, and the stimulation of your salivary flow — such as through the use of sugarless hard candies. Nonsteroidal anti-inflammatory drugs (NSAIDs) may help relieve your discomfort and inflammation. Please see the web pages for more details on Sjogren syndrome. Answered by Lawanna Shimon 2 years ago.

Sjogren's Syndrome is a chronic autoimmune disease. There is no such thing as a cure or recovery. All you can do is treat the symptoms. For the dryness, your doctor may prescribe drugs that stimulate your glands to produce more mucus and saliva, or recommend that you use gum or candies to help lubricate your throat. If you have extraglandular involvement, you might also take corticosteroids or non-steroidal anti-inflammatory drugs (NSAID's) to relieve pain and inflammation. If those treatments fail to provide relief, you may be prescribed immunosuppresants. Answered by Nickie Ritchhart 2 years ago.

This Site Might Help You. RE: How can you Recover/Cure Sjogren's Syndrome ??? How can you cure or recover Sjogren's syndrome ?? Answered by Mallory Spizzirri 2 years ago.

Dry, Bloodshot Eyes?
Ok well a while back I noticed my eyes were starting to get red from using my computer alot, so I decided to use Visene. This worked, but I was dumb enough to go right back on my computer for a very long time so they became red again. At the time, I did not know the harmful effects visene had on your eyes, and I... Asked by Librada Gironda 2 years ago.

Ok well a while back I noticed my eyes were starting to get red from using my computer alot, so I decided to use Visene. This worked, but I was dumb enough to go right back on my computer for a very long time so they became red again. At the time, I did not know the harmful effects visene had on your eyes, and I overused it. I got trapped in the "rebound effect" as they call it, and it eventually made my eye redness worse, and more common. To this date, my eyes are red EVERYDAY. They are really red when I wake up in the morning, and slightly dim as the day goes on, but when I look in the mirror I can still see reddened blood vessels all over my eyes. My eyes are also very dry all the tme, and I blink almost every second. Is there anyway to reverse this? I havent used visene in over a week, but my eyes seem to almost rely on it now. Any suggestions? Answered by Mervin Butzlaff 2 years ago.

I'd say see an optomotrist to get an answer but i found this... Dry Eye Syndrome Treatment Self-Care at Home To help alleviate your symptoms from DES, you may want to try these self-help tips at home. A humidifier puts more moisture in the air. With more moisture in the air, your tears evaporate more slowly, keeping your eyes more comfortable. Both furnaces in the winter and air conditioning in the summer decrease the humidity in the air. Excessive air movement dries out your eyes. Avoid having excessive air movement by decreasing the speed of ceiling fans and/or oscillating fans. Hot compresses and eyelid scrubs/massage with baby shampoo help by providing a thicker, more stable lipid layer. . The heat warms up the oil in the oil glands, making it flow more easily; the massaging action helps get the oil out of the glands. The cleansing action decreases the number of bacteria that break down the oil. Artificial tears and lubricating eyedrops and gels (available over the counter) help provide more moisture and lubrication for the surface of your eye. They are typically used about four times a day, but they can be used as often as needed. Preservative free solutions are recommended if you wish to use tears more than six times a day. Lubricating eye ointments are much thicker than eyedrops and gels. Because ointments are so thick, they last much longer than eyedrops and gels. However, because of their thickness, ointments may blur your vision if used during the day. Therefore, they are typically used to lubricate the eyes overnight while you are asleep. If you notice your eyes are dry mainly while you are reading or watching TV, taking frequent breaks to allow your eyes to rest and become moist and comfortable again is helpful. Medical Treatment Although no cure exists for DES, many treatments are available. Treatment is dependent on the severity of DES; you may only require a humidifier or occasional eyedrops, or you may require surgery to help decrease DES. Over-the-counter lubricating eyedrops, commonly referred to as artificial tears, may help relieve your dry eyes. Some examples of these products include 20/20 Tears, Celluvisc, Comfort Tears, Dry Eyes, Murine, Refresh, and Tears Naturale. Your ophthalmologist may also prescribe medications to help with DES. Medications Certain prescription medications may help with DES. Eye lubricants may be prescribed, such as Lacrisert, an artificial tear insert. The insert is similar to a contact lens and is inserted 1-2 times per day. Cellulose is contained in the insert and acts to stabilize and thicken the film of tears over the eyes and to prolong the time the tear film works. The artificial tear insert must be properly inserted, otherwise corneal abrasion may occur. Cyclosporine A 0.5% (Restasis) helps decrease any inflammation on the surface of your eye. This inflammation is thought to decrease the ability of your eyes to maintain a healthy tear film. Used twice a day, cyclosporine 0.5% helps you make more, healthier tears on your own. Antibiotics are used if you have blepharitis or meibomian gland dysfunction. Antibiotic ophthalmic ointments, such as erythromycin and bacitracin, among others, are used at night for about 7-10 days to decrease the number of bacteria that break down the lipid layer of your tear film. These ointments also lubricate your eyes overnight. Oral antibiotics, particularly tetracycline and doxycycline, not only help to decrease the number of bacteria but also help to make the oil more fluid so it flows out of the oil glands more easily. Answered by Yan Rieth 2 years ago.


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