GLEEVEC Ressources

Application Information

This drug has been submitted to the FDA under the reference 021335/001.

Names and composition

"GLEEVEC" is the commercial name of a drug composed of IMATINIB MESYLATE.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
021335/001 GLEEVEC IMATINIB MESYLATE CAPSULE/ORAL EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
021335/002 GLEEVEC IMATINIB MESYLATE CAPSULE/ORAL EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
021588/001 GLEEVEC IMATINIB MESYLATE TABLET/ORAL EQ 100MG BASE
021588/002 GLEEVEC IMATINIB MESYLATE TABLET/ORAL EQ 400MG BASE

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
021335/001 GLEEVEC IMATINIB MESYLATE CAPSULE/ORAL EQ 50MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
021335/002 GLEEVEC IMATINIB MESYLATE CAPSULE/ORAL EQ 100MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
078340/001 IMATINIB MESYLATE IMATINIB MESYLATE TABLET/ORAL EQ 100MG BASE
021588/001 GLEEVEC IMATINIB MESYLATE TABLET/ORAL EQ 100MG BASE
078340/002 IMATINIB MESYLATE IMATINIB MESYLATE TABLET/ORAL EQ 400MG BASE
021588/002 GLEEVEC IMATINIB MESYLATE TABLET/ORAL EQ 400MG BASE
079179/001 IMATINIB MESYLATE IMATINIB MESYLATE TABLET/ORAL EQ 100MG BASE
079179/002 IMATINIB MESYLATE IMATINIB MESYLATE TABLET/ORAL EQ 400MG BASE
204285/001 IMATINIB MESYLATE IMATINIB MESYLATE TABLET/ORAL EQ 100MG BASE
204285/002 IMATINIB MESYLATE IMATINIB MESYLATE TABLET/ORAL EQ 400MG BASE
204644/001 IMATINIB MESYLATE IMATINIB MESYLATE TABLET/ORAL EQ 100MG BASE
204644/002 IMATINIB MESYLATE IMATINIB MESYLATE TABLET/ORAL EQ 400MG BASE

Ask a question

A licensed doctor will try to answer your question as quickly as possible.

Answered questions

Information on Gleevec?
Hi everyone. I am doing a research paper on the different types of treatments for cancer. I'm looking for more information on Gleevec. Anything would be helpful. Thanks Asked by Jimmie Macki 1 month ago.

You can start with the Gleevec website: Answered by Tiffaney Pelot 1 month ago.


Can retinoblastoma be treated with the cancer drug gleevec?
Asked by Dong Lambeck 1 month ago.

Using gleevec for retinoblastoma would not be considered a standardized approach as there are other first and second line treatments available. Gleevec has only been proven beneficial/effective in chronic myelogenous leukemia (CML) and gastointestinal stromal tumors (GIST). In cllinical trials for other types of cancer gleevec has not been as effective as a single agent. What gleevec has done is open up the door of possibility for other tyrosine kinase inhibitor drugs to be developed that will target different cancer types (includes Sunitinib, Dasatinib, Erlotinib, Sorafenib, etc) So the answer is . . probably not . . you might try researching clinical trial information about the drug, but retinoblastoma probably doesn't have the 'targets' needed in the tumor for the drug to be effective against it. Answered by Margot Margaryan 1 month ago.


If someone is diagnosed with Philadelphia chromosome and is taking gleevec without leukemia?
will leukemia still develop or will the gleevec fix the disorder Asked by Becki Landsaw 1 month ago.

Gleevec treats leukemia patients (with CML) that are positive for the Ph chromosome specifically. Two things can happen to a CML patient taking Gleevec. The cancer can disappear completely for the rest of the patient's life, and the Ph chromosome becomes non-detectable even using advanced molecular techniques. This is called a molecular complete response. But more often, a few of the leukemic cells are resistant to the effects of Gleevec and they slowly take over and become the majority of cells. Then the patient has developed Gleevec resistant CML, and must choose a new therapy, such as Tasigna. So to answer your question, sometimes Gleevec fixes the disorder and sometimes leukemia still develops. I'm sorry that this is probably not very satisfying. If the Ph-positive leukemic cells disappear from the bone marrow, this is a very positive prognostic factor. Answered by Oscar Koria 1 month ago.


Gleevec and colon cancer?
http://www.cancerfacts.com/Home_News.asp?CancerTypeId=4&NewsId=2157 Asked by Chan Coppler 1 month ago.

The link you present is about treatment of GIST in the colon, for which Gleevec is effective and used as standard treatment (In addition to surgery). The most common cancers are "adenocarcinomas". As Pandas second link shows Gleevec has only demonstrated effect in cell lines. You can´t conclude directly from effect on cell lines to effect on whole cancers, but it is an interesting observation. To be useful for treatment it has to be clinically at least as effective as drugs available. Answered by September Duplechin 1 month ago.


Taking gleevec for leukemia and makes me sick?
I can barley go to work because i get so sick from it so i stopped taking it for now. Anything i can do to help me not feel and get sick? Please help! My doc is stupid she said its normal. But when i have a freakin life i cant live cus i feel horrible! Asked by Valentina Jerde 1 month ago.

Find a new doctor. A relative should help you search for one, if not, look on the internet. Answered by Gilma Bickell 1 month ago.


Hi all, Could someone tell me the address of hospitals that heal blood cancer disease with gleevec medicine?
It's immidiately.. Asked by Ehtel Pemble 1 month ago.

Gleevec is now standard first line therapy for CML in the USA. In other words, any hematologist/oncologist at any hospital should be able to provide it. If you have something other than CML (GIST, Ph+ ALL, etc.), you will probably need an oncology to prescribe it off label. Answered by Jessia Grzebien 1 month ago.

It is not just a simple case of "healing" bone cancer, you really have a 50% - 50% chance of being cured .. My mother has leukemia and the best leukemia medicine is currently in trial phase in Australia and should almost be out of trial phase in America. You really should see a PROFESSIONAL in regards to blood cancer (leukemia) and your doctor should refer you to one .. I believe Oncologists handle leukemia. If you catch leukemia in time, you have a very good chance of survival and normal life, but you are generally never cured .. you must always endure blood tests, bone marrow tests, and take your pills for the rest of your life. Answered by Dara Sebold 1 month ago.

Rev Kip - The moon God, WTF? and you're a non secular chief? Explains lots pertaining to to the recommendations-set of a super sort of Christians available... *Shakes Head* Do you now no longer comprehend that Muslims (and a super sort of Jews) hint the origins of Islam lower back to the 1st infant of Abraham, who God additionally stated ought to the be the daddy of a super human beings? So do you carry it against Jesus that his mom and dad weren't christian? thinking Mohammed based the religion, of direction he grew to become born good right into a diverse one. and those loopy reference you made pertaining to to the pagan daughters he allegedly worshiped, you need to desire to earnings fairly extra advantageous. Mohommed relatively denouced all scripture concerning to them as "The Satanic Verses" and stated such ideals had no place in a monotheistic relgion. after all, directly to answering the question. placed as much as in recommendations, I talk of the broader Christian recommendations-set, and not the quite faith itself which preaches tolerance of others... Christianity has never enjoyed diverse religions. to incorporate Judaism. easily everybody remember the Inquisition? Or the reality that Pope John Paul II admitted that the church bore some accountability for the holocaust by ability of utilising actuality of it is intolerence of Jews? Ever heard the age previous tale that we use the blood of a christian innocuous to make our passover matzah? Christians decide to piggy lower back off of our faith so they have have been given a love hate courting with us, yet usual can not denounce us by ability of utilising actuality they did borrow our God and not any incorrect way around. the at cutting-edge out hate for Muslims comes from the reality that collectively as Jews purely might desire to get with this gadget, Islam grew to become formed after the demise and hoopla of Jesus. we don't decide to grandfather clause him in, yet they outright rejected him. Oh, that and Christians seem an intollerant lot because of the fact it is (lots to Jesus's chagrin, i'm particular). Answered by Carmen Johanson 1 month ago.


Is there anyone else out there that has to take Gleevec?
Thank you both for answering my question - I appreciate the input. Asked by Loreen Lasseigne 1 month ago.

I dont know the details, but my great aunt has cml and takes gleevec. I dont know her dosage, but she weighs roughly around 180 (I would guess roughly a size 16). Again I dont know details but I do know she has some side effects. I unfortunatly cant tell you exactly what they are though. Wiki has a lot of info on both cml and gleevec if go over there and look. www.wikipedia.com I am aml and thogh I have no expereince with gleevec, I do have leukemia experience. Feel free to contact me if you want there is a link on my profile. I dont know of how much help I can be specifically, but I do know what its like to need someone else to talk to who 'gets' it. Answered by Avery Ina 1 month ago.


I have to take gleevec for leukemia and its hard to work because it makes me so sick?
What can i do to help me not get and feel sick? I stopped taking it for now cus i hate it! Please help! Asked by Porsha Softich 1 month ago.

Gleevec is very unpredictable in side effects. It's also hugely expensive. Tell your doctor you stopped. Answered by Lakendra Golan 1 month ago.

Gleevec is one of the first designer drugs that can stop chronic myeloid leukemia developing into acute myeloid leukemia which needs much more aggresive chemotherapy and has a high risk of dying. Are you feeling better after stopping gleevec? You should make an earlier appointment with your hematologist to discus your symptoms. Being tired and nauseous can be due to the Gleevec, but part of your feeling unwell might be because you are shocked, anxious and frightened and maybe depressed after hearing about your diagnosis. Is there a nurse specialist of social worker in your treatment team with whom you can speak about your problems? I hope so. I wish you all the best for the future! Answered by Barrie Krys 1 month ago.


I need FREE Gleevec?
My Husband's Aunt in the Philippines has a Mild Leukemia and the doctor suggest a medicine named Gleevec. Do you know any foundation who can give a Free medicine. My Aunts is from the Philippines I understand that some of the foundation gives free medicine in the US but my husband aunt is in the Philippines. .... Asked by Jessika Juncker 1 month ago.

My Husband's Aunt in the Philippines has a Mild Leukemia and the doctor suggest a medicine named Gleevec. Do you know any foundation who can give a Free medicine. My Aunts is from the Philippines I understand that some of the foundation gives free medicine in the US but my husband aunt is in the Philippines. . We already send an application to Max foundation. Do you still know any foundation aside from this? Answered by Lynn Scammon 1 month ago.

Years ago when I worked in Oncology, the pharmaceutical company that makes Gleevec offered a program for those with financial inability to pay for it. Go to the website for Novartis Pharmaceuticals, make contact directly to them and inquire as to whether they still offer such a program for free or reduced rate Gleevec. Novartis will tell you what the requirements are and how they will affect manang. Answered by Conchita Dimuzio 1 month ago.


If someone has the Philadelphia chromosome and they are being treated with Gleevec will the leukemia be gone?
Asked by Karry Truly 1 month ago.

Nope. Gleevec eventually stops working for most people who don't die of unrelated causes during treatment, and some patients discontinue using it before it stops working because of side effects. It, along with tasigna and sprycel, offer much more effective treatment than the older generation of drugs, but they are by no means a cure. Answered by Doretha Matchen 1 month ago.

Hello Short answer..... No Long answer..... if you are talking about CML(of course Ph+ ALL is anther beast)..... there are patients with prolooooong molecular remission from the original IRIS trial but we know that if we stop treatment the disease will come back. The whole concept of leukemic stem cell, the eye-talians have reported durable remission off of gleevec after being on molecular remission but many relapsed and ones that had interesting long remission after discontinuing gleevec were patients who had IFN prior to gleevec. So conclusion --> NO Answered by Malvina Soliman 1 month ago.


Related

Browse by letter
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

© Medications.li 2015-2017 - Blog - All rights reserved