FLORINEF Ressources

Application Information

This drug has been submitted to the FDA under the reference 010060/001.

Names and composition

"FLORINEF" is the commercial name of a drug composed of FLUDROCORTISONE ACETATE.

Answered questions

Can the steroid Florinef have bad long term side effects if taken for an extened period?
im a 21yr old female in the usa, ive been on 0.1 mgs of Florinef for over 2yrs for neuro cardiogenic snycope Asked by Flora Hannan 4 months ago.

Florinef (Fludrocortisone) is usually taken long term so in terms of having bad side effects if taken long term, you would probably be worse off if you didn't take it. Dose depends on the severity of the disease and the response of the patient. Patients should be continually monitored for signs that indicate dosage adjustment is necessary, such as remissions or exacerbations of the disease and stress (surgery, infection, trauma). Fludrocortisone tablets are indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome. In Addison's disease - the usual dose is 0.1 mg of Fludrocortisone daily, although dosage ranging from 0.1 mg three times a week to 0.2 mg daily has been employed. In the event transient hypertension develops as a consequence of therapy, the dose should be reduced to 0.05 mg daily. Fludrocortisone acetate is preferably administered in conjunction with cortisone (10 mg to 37.5 mg daily in divided doses) or hydrocortisone (10 mg to 30 mg daily in divided doses). Salt-Losing Adrenogenital Syndrome - the recommended dosage for treating the salt-losing adrenogenital syndrome is 0.1 mg to 0.2 mg of Fludrocortisone acetate daily. Sometimes it doesn't cause any side effects at all, and sometimes it may cause extreme side effects in some people. Also, adverse effects may occur as your body or circumstances changes. Please see the attached source link. To get a better idea of the side effects that MAY occur please read under "Adverse Reactions". Answered by Zada Calais 4 months ago.

Florinef Side Effects Answered by Malena Ritcher 4 months ago.


What could happen if you were to suddenly stop taking Florinef after taking it for 2yrs?
Asked by Shelby Netzel 4 months ago.

Florinef is used as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome. Which reason are you taking it? That will make a difference in what type of symptoms you may have after discontinuing it. I wouldn't recommend stopping it without speaking first with your physician. Answered by Tommy Roblow 4 months ago.


The pill Florinef, my cardiologist gave it to me to control passing out, does that make any sense?
Im 19yrs old, if anyone can offer me some help with this please im me Asked by Evia Dimopoulos 4 months ago.

What is your condition? Florinef Use - Treatment of Addison's disease; partial replacement therapy for adrenal insufficiency; treatment of salt-losing forms of congenital adrenogenital syndrome; has been used in conjunction with an increased sodium intake for the treatment of idiopathic orthostatic hypotension You should talk with your doctor about what your disease is and how the medication will help. Answered by Sherika Biffle 4 months ago.

Florinef is a mineral corticoid, It will increase your blood volume by helping you retain salt. In turn will increase your blood pressure. I am assuming your syncope was from low blood pressure. What kind of work up did you have done? Did they do any adrenal testing? If you don't understand your condition or what the medication is for please talk with your doctor. Answered by Maryanna Labs 4 months ago.

my doctor gave me the same thing for the same problem. it didn't help me at all... i just swelled up really bad. ask what is causing you to pass out. tell them you want to know what is the main problem... sounds like he's just treating the symptoms instead of taking care of the main problem. be persistant... i found out what my main problem was and now I feel much better Answered by Denny Fastic 4 months ago.


Anyone taking Florinef because of low sodium but have NOT been diagnosed with Addison's disease?
I am taking Florinef because my sodium level is low and I think I may have Addison's disease but I am wondering if anyone else has just low sodium without a disease.Thanks Asked by Junko Frankland 4 months ago.

you need a proper diagnosis first. Answered by Melani Pepe 4 months ago.

Florinef is also used by patients with salt-losing form of Congenital Adrenal Hyperplasia. There is an occult form of the disease that may go unrecognized into adulthood. Agree with other responder who said you need a proper diagnosis. Have you seen an endocrinologist? Answered by Freddie Pearl 4 months ago.


Levaquin and Florinef... what now?
While looking up the side effects of my current antibiotic (Levaquin) I came across a warning about a drug I have taken regularly for the past two years - florinef. Apparently it is not a good idea to mix the two because tendon ruptures can occur months after you finish the treatment. Unfortunately, this is my... Asked by Mallie Tupy 4 months ago.

While looking up the side effects of my current antibiotic (Levaquin) I came across a warning about a drug I have taken regularly for the past two years - florinef. Apparently it is not a good idea to mix the two because tendon ruptures can occur months after you finish the treatment. Unfortunately, this is my second batch of Levaquin (I started the first batch exactly a month ago for ten days for this same reoccurring sinus infection). I feel very torn about what to do now - Levaquin has done wonders for making me feel better, but I'm concerned about the side effects now. However, since it's already in my system from the first batch - will it make that much of a difference to stop them now? Are there any preventative measures I can take to prevent a tendon from rupturing - just in case? I work as a Kindergarten teacher, so I have to be on my feet all day! Thank you for any advice! Answered by Miki Motto 4 months ago.

Levofloxacin is used treat infections such as pneumonia; chronic bronchitis; and sinus, urinary tract, kidney, and skin infections. Levofloxacin is in a class of antibiotics called fluoroquinolones. It works by eliminating bacteria that cause infections. Fludrocortisone, a corticosteroid, is used to help control the amount of sodium and fluids in your body. It is used to treat Addison's disease and syndromes where excessive amounts of sodium are lost in the urine. It works by decreasing the amount of sodium that is lost (excreted) in your urine. Please see the web pages for more details on Levofloxacin (generic name) Levaquin (brand name) and Fludrocortisone Acetate (generic name) Florinet (brand name). Answered by Kymberly Mahapatra 4 months ago.

I won't supersede the advice of your physician and I simply don't know whether Florinef enhances the tendon pathology that's been so media-hyped as of late. The fluoroquinolines, e.g. Levaquin have gotten a really raw deal after the data about some cases of tendon pathology. The truth is that we've used these superb medications for many years with superb experience. I've never seen tendon pathology as an untoward event in a patient and I don't hesitate to use the fluoroquinolones. I'd have to research how it interacts with Florinef to see how much of an increased risk it is as I'm not a pharmacologist, but I really feel that the public has been unfairly made to feer the fluoroquinolones b/c of some instances of tendon pathology in a small subset of patients. It's almost like we're throwing the baby away with the water with the DNA gyrase inhibitors and how much bad press they get. Answered by Gaynell Hollinrake 4 months ago.

The fluoroquinolones, in and of themselves, may cause spontaneous tendon ruptures long after you have stopped taking the medication. (over a year) Of all the fluoroquinolone drugs, levaquin is by far the most dangerous regarding side effects. There is nothing you can really do to prevent such a rupture from taking place. It is a myth that only those who are extremely physically active, or elderly, may suffer such a reaction. This occurs in all ages groups regardless of whether or not they are physically active. Additional severe adverse reactions to be concerned about is irreversible peripheral nueropathy, fatal liver damage, ruptures of muscles and ligaments, fatal hypo and hyperglycemia, vision damage, SJS and TEN, disfiquring rashes, severe anxiety, CNS as well as PNS damage that last for years. Within the new drug application for levaquin it was reported to have an adverse drug reaction rate in excess of 40%. (one or more reactions) More than half of the drugs within this class have been removed from clinical use due to such toxicity issues. The concurrent use of any steroid drug (which florinef is) greatly increases your risk of such reactions taking place. The FDA recently added Black Box Warnings concerning the tendon issue and additional Black Box Warnings and Dear Doctor Letters are being sought concerning the other horrendous side effects associated with this class. The problem you now face is the rampant ignorance found within the medical community regarding the safety profile of this class. But regarding your question it is clearly stated within the package insert NOT to take a steroid drug while undergoing fluoroquinolone therapy. If you experience ANY kind of tendon pain rest the affected tendon and stop taking the levaquin immedately. I would also request that your physician at least read the package insert regarding the proper use of this drug. It appears that he or she has failed to do so. There are numerous discussion forums on the Internet regarding the lifelong damage these drugs can cause, that have been on line for over a decade now. As well as a number of consumer advocacy groups, including Public Citizen and the Attorney General of the State of Illinois, that have been battling with the FDA to get adequate warnings as well as Dear Doctor Letters concerning this outrageous and dangerous safety profile. My advice to you would be to log on to www.fqresearch.org and read the over 4000 medical journal entries found there, published in the leading medical journals, that document all that I have stated here before discussing your concerns with your physiciain who I assure you has no knowledge concerning the true safety profile of this class. Answered by Kristen Emigh 4 months ago.


Does Florinef cause weight gain?
Asked by Kyoko Kilts 4 months ago.

All details are on their home page. Answered by Lashon Cederberg 4 months ago.


Does anyone take florinef 0.1mg ?
I take it for fainting. Does it help? Asked by Cletus Khensamphanh 4 months ago.

I don't take it but i can affirm it is effective for treating fainting due to hypotension. .1mg is a common dose for this drug and may even be high for some patients with pre-existing hypertensive issues. Answered by Bud Buss 4 months ago.


How much of a 0.1mg tablet of florinef is steroid?
my dog takes 9 x 0.1 mg florinef daily for Addison's disease and I want to know how much steroid he is receiving daily from this. Asked by Felicitas Monske 4 months ago.

Each tablet has 0.1 mg of fludrocortisone therefore your dog is taking 0.9 mg of steroid. Answered by Hayley Vassey 4 months ago.


How soon does florinef (fludorcortisone) work for dizzy spells?
I'm supposed to take it only during dizzy spells. SO what would happen if I took it during a dizzy spell but my blood pressure is 110/70 (not really low)? Not sure why I'm so dizzy but my bp is normal right now. Might I feel worse taking it for my dizziness if my bp is normal? Asked by Muoi Krenke 4 months ago.

√ Casting a spell takes time, as do waiting for the results of a spell, you have to have patience if you want this to work. Answered by Margherita Carranco 4 months ago.


Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
010060/001 FLORINEF FLUDROCORTISONE ACETATE TABLET/ORAL 0.1MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
010060/001 FLORINEF FLUDROCORTISONE ACETATE TABLET/ORAL 0.1MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
040425/001 FLUDROCORTISONE ACETATE FLUDROCORTISONE ACETATE TABLET/ORAL 0.1MG
040431/001 FLUDROCORTISONE ACETATE FLUDROCORTISONE ACETATE TABLET/ORAL 0.1MG
091302/001 FLUDROCORTISONE ACETATE FLUDROCORTISONE ACETATE TABLET/ORAL 0.1MG

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