EPINEPHRINE Ressources

Application Information

This drug has been submitted to the FDA under the reference 087907/001.

Names and composition

"EPINEPHRINE" is the commercial name of a drug composed of EPINEPHRINE.

Answered questions

The adrenal _________ produces epinephrine?
The adrenal _________ produces epinephrine Asked by Fletcher Glatter 4 months ago.

The adrenal glands produce epinephrine; also known as adrenaline. Specifically, epinephrine is produced by the adrenal medulla. The purpose of epinephrine is to regulate the body during excitatory situations such as fear and excitement. For example, when a dog chases you, your heart starts beating really fast. This is due to epinephrine stimulating the hearts nerves. Adrenaline also turns up respiration, constricts breathing, raises blood pressure and excites muscles, which makes you stronger and faster. This is why a lot of people become thrill seekers AKA "adrenaline junkies." They love the fearful rush they get from forcing their adrenal glands to produce epinephrine over and over again. The opposite hormone of adrenaline is noradrenaline (norepinephrine). This hormone actually has the reverse effect on the body's metabolism. It slows heart rate, dilates blood vessels and lowers blood pressure. The purpose of this is to bring you back to balance after being so filled with epinephrine. This process as a whole, epinephrine and norepinephrine, is called "the body's fight or flight response." Hope that helps! Answered by Assunta Winesberry 4 months ago.

Some persons right here are becoming careworn, the asker is just not asking concerning the medulla oblongata within the mind however in regards to the ADRENAL medulla! Sitting on high of the kidneys are two, fairly small, adrenal glands, each of which secrete major hormones into the circulation. The adrenal gland is made from 4 sensible layers certainly. Going from within to out: the adrenal medulla (which secretes catecholamines, adrenaline, noradrenaline and so forth), the adrenal cortex surrounds this together with zona reticularis, zona fasciculata and zona glomerulosa, (the reticularis and fasciculata produce cortisol hormone, and the outermost glomerulosa produces aldosterone). The adrenal medulla is also known as a postganglionic neurone, on the grounds that it is directly inspired by preganglionic sympathetic fibres to provide adrenaline, so is viewed to be a part of the sympathetic apprehensive process. If you happen to get harassed between medulla and cortex, the medulla is invariably at the centre and is surrounded by using the cortex, (actual for hair shafts, thymus, spleen etc) Answered by Toccara Kopke 4 months ago.

gland more specifically the Adrenal Medulla The Adrenal Gland. This gland is divided into two categories, the Adrenal Cortex and the Adrenal Medulla. The Adrenal Medulla produced epinephrine and norepinephrine. Answered by Jacquline Haubert 4 months ago.

adrenal gland. and if want to be more specific it is adrenal medulla. Answered by Marguerite Balasko 4 months ago.


Explain the relationship between epinephrine and norepinephrine?
This question is from chemical regulation chapter...i really confused what to answer.... Asked by Gertude Zadroga 4 months ago.

In a airplane triangle, the sum of the within triangles is consistently one hundred eighty levels. If one angle is ninety, then the opposite two ought to add up to 90. ----- Mark the three angles as A, B and C (C being ninety levels). Mark the edges opposite the corresponding angles as a, b and c (c being the hypothenuse, reverse the ninety measure perspective C). Sin(A) = a/c Cos(A) = b/c Tan(A) = a/b Cos(B) = a/c Sin(B) = b/c Cot(B) = a/b Answered by Aleshia Audia 4 months ago.


Epinephrine and Ephedra?
Don't people take ephedra for energy? If so, why is the most common side effect for epinephrine fatigue? Is it because epinephrine is a non-selective adrenergic agonist? Can someone explain how epinephrine works? Thanks Asked by Joe Depugh 4 months ago.

Epinephrine plays a central role in the short-term stress reaction—the physiological response to threatening, exciting, or environmental stressor conditions . It is secreted by the adrenal medulla. When released into the bloodstream, epinephrine binds to multiple receptors and has numerous effects throughout the body. It increases heart rate and stroke volume, dilates the pupils, and constricts arterioles in the skin and gut while dilating arterioles in leg muscles. It elevates the blood sugar level by increasing catalysis of glycogen to glucose in the liver, and at the same time begins the breakdown of lipids in fat cells. Like some other stress hormones, epinephrine has a suppressive effect on the immune system. Epinephrine is an endocrine secretion from adrenal medulla and there is no feedback mechanism. More epinephrine or ephedra releases more glycogen from muscles,and liver virtually rendering the individual "temporarily" diabetic. This causes more urination,loss of electrolytes. This causes weakness. Answered by Dion Rementer 4 months ago.

It was typically used for asthma..but because of the blood flow increase and weight loss..it became abused by some to give that extra boost..which resulted in some deaths. Drug makers used it to make meth. And because of that....people like me who take over the counter drugs for asthma have been ignored of our need for the sake of safety...and most of the drugs have been banned...which makes those that have no insurance to suffer. But to answer your question...yes they did...it's a banned substance in most professional sports....the fatigue is caused by the heart rate being increased by the drug....it can be fatal if taken too much. Answered by Concetta Stephson 4 months ago.


Under what circumstances would you give epinephrine or atropine to get heart started?
Epinephrine vs. Atropine Asked by Merna Dellow 4 months ago.

Epinephrine was used in heroin/morphine/opium overdoses due to slowing of breathing and heart rate caused by the drugs depressant effect, but they now use naloxone in favor of adrenaline because it completely blocks the effects of morphine (heroin and opium are essentially morphine) but i suppose adrenaline would would in any depressant drug that slows breathing and heart rate to, also Epinephrine is used to treat Anaphylaxis in severe allergic reactions, the auto-injectors are sold/given to people in kits, they are called Epi-Pens "Atropine and related anticholinergic drugs act as antidotes to nerve agent poisoning because they block acetylcholine receptors, but they are poisonous in their own right" Not sure if that has anything to do with its effect on increasing heart rate. I'm not sure why else they would use atropine in favor of adrenaline as it is a deadly poison and adrenline is natural. Answered by Virgil Filipek 4 months ago.


How can epinephrine be increased in the body? Can it be done naturally?
If not how can it be done without an Epi-Pen and how is it created. I am also curious as to how epi pens work. Please include a reference or website if possible Asked by Jean Mcdeavitt 4 months ago.

Epinephrine is produced in many tissues (e.g. lungs), but most of the hormone is synthesized in, and released by the adrenal glands in response to signals from the sympathetic nervous system. These signals are triggered by stress, exercise, or by emotions such as fear. Epinephrine has many actions, both local and systemic. For example, injected into vascular beds just under the skin, it can prevent bleeding associated with a scalpel incision. It also acts systemically: in the brain, it causes anxiety, it increases blood pressure by causing vascular smooth muscle constriction, it increases the heart rate, relaxes smooth muscle causing bronchodilation in lung tissue ... it's certainly not a drug to experiment with using an Epi-Pen. Epi-Pens deliver a large amount of epinephrine into muscle where it gets absorbed into the blood -- as a (potent) beta agonist, an Epi-pen reverses cardiovascular, cutaneous, GI, and pulmonary manifestations of anaphylaxis by acting on beta-adrenergic receptors on smooth muscle (the effects are tissue-specific, so, as mentioned, smooth muscle in the lung tissue dilates, whereas smooth muscle in arteries constrict). One way to increase epinephrine naturally is to exercise ;-) Answered by Josef Muhlbach 4 months ago.

You want to increase your natural epinephrine? Swim with sharks. Run from the cops. Have a near miss auto accident. Increased epinephrine (adrenaline) is part of the "fight or flight" response. Too much epinephrine can cause dangerous increases in blood pressure and heart rate, so you don't want to play with an Epi-Pen unless you need it to survive a severe allergic reaction. Answered by Lorriane Ekin 4 months ago.


Effects of epinephrine?
What effect does epinephrine have on the GI tract, eyes and bladder? Asked by Wendolyn Hartje 4 months ago.

epinephrine can cause nausea and vomiting. it works on the sympathetic nervous system, constricting blood vessels that aren't 'necessary' in the fight or flight response. so the bladder and gi tract experience less blood flow, meanwhile the senses are heightened, ie, pupils dilate. direct administration of epinephrine to the eyes in prescription eye drops is used for glaucoma and can, as a side effect, color the conjunctiva, or white, or the eye due to recruitment of melantoin/melanin. Answered by Scarlet Crum 4 months ago.


Epinephrine for respiratory distress?
My counties protocol says to administer epi. to patients in repiratory distress associated with reactive airway disease, asthma, bronchospasm, croup and stridor. I'm a little unclear about epi's effects. Asked by James Schmidt 4 months ago.

Epinephrine is also known as adrenaline which is the key neurotransmitter in the fight-or-flight response of the sympathetic nervous system. This response has a great impact throughout your body: it will contract blood vessels, increase heart rate, dilate pupils, and most importantly, will cause bronchodilation - among other things. There is a form of epinephrine called racemic epinephrine that is nebulized to aid in the treatment of croup and stridor by reducing upper airway swelling. Patients who receive any form of epinephrine need to be monitored for a couple hours, just in case they develop arrhythmias, or paradoxical bronchospasm. Answered by Janet Sink 4 months ago.


List some effects of epinephrine.?
BIO 160 LPN Program Asked by Marquita Lidster 4 months ago.

Epinephrine is otherwise known as adrenaline. This causes 'flight or fight' response. When secreted into the bloodstream, it rapidly prepares the body for action in emergency situations. The hormone boosts the supply of oxygen and glucose to the brain and muscles, while suppressing other non-emergency bodily processes (digestion in particular). It increases heart rate and stroke volume, dilates the pupils, and constricts arterioles in the skin and gastrointestinal tract while dilating arterioles in skeletal muscles. It elevates the blood sugar level by increasing catabolism of glycogen to glucose in the liver, and at the same time begins the breakdown of lipids in fat cells. Like some other stress hormones, epinephrine has a suppressive effect on the immune system. The type of action in various cell types depends on their expression of adrenergic receptors. Answered by Hoa Klimek 4 months ago.

epinephrine increases glycolsis(glucose breakdown), glycogenolysis(glycogen degradation) & lipogenesis(lipid production). it also increases heart beat rate and cardiac out put. Answered by Santo Vanschuyver 4 months ago.


Whattt is epinephrine?
What does is it mean when someone is on epinephrine? Asked by Trent Lecznar 4 months ago.

Epinephrine is used in severe allergic reactions; anaphylactic shock. It is the active ingredient in the Epi Pen. It can be used in the gums during some dental procedures to act as a numbing agent, and may be used in the short term to treat some heart conditions. Generally someone isn't "on" epinephrine; it is usually a one-time dose or a closely monitored series of doses. Answered by Kiara Wanders 4 months ago.

If this person is saying they are on epinephrine, then they probably carry an EpiPen used for extreme allergic reactions. Both adrenaline and the synthetic epinephrine cause the heart to beat faster and decrease blood presure. Answered by Natalya Riveron 4 months ago.

epinephrine is an adrenaline hormone. If you've ever heard of the fight or flight response... well it is the hormone that is released from your brain into your blood stream to gives you that adrenaline rush. Answered by Trinidad Filyan 4 months ago.

Basically, it's adrenaline. It's used for severe allergic reactions, and cardiac arrest. Answered by Cherrie Bucholtz 4 months ago.

i bet google would have been faster for this! it's adrenaline Answered by Cameron Bommarito 4 months ago.


Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
087907/001 EPINEPHRINE EPINEPHRINE AEROSOL, METERED/INHALATION 0.2MG per INH
205029/001 EPINEPHRINE EPINEPHRINE SOLUTION/IV (INFUSION), INTRAOCULAR, INTRAMUSCULAR, SUBCUTANEOUS EQ 1MG BASE per ML (EQ 1MG BASE per ML)

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
007942/001 SUS-PHRINE SULFITE FREE EPINEPHRINE INJECTABLE/INJECTION 5MG per ML
007942/003 SUS-PHRINE SULFITE FREE EPINEPHRINE INJECTABLE/INJECTION 1.5MG per AMP
016126/001 PRIMATENE MIST EPINEPHRINE AEROSOL, METERED/INHALATION 0.2MG per INH
016803/001 BRONKAID MIST EPINEPHRINE AEROSOL, METERED/INHALATION 0.25MG per INH
019430/001 EPIPEN EPINEPHRINE INJECTABLE/INTRAMUSCULAR, SUBCUTANEOUS 0.3MG per DELIVERY
019430/002 EPIPEN JR. EPINEPHRINE INJECTABLE/INTRAMUSCULAR, SUBCUTANEOUS 0.15MG per DELIVERY
019430/003 EPIPEN E Z PEN EPINEPHRINE INJECTABLE/INTRAMUSCULAR 0.3MG per DELIVERY
019430/004 EPI E Z PEN JR EPINEPHRINE INJECTABLE/INTRAMUSCULAR 0.15MG per DELIVERY
020800/001 TWINJECT 0.3 EPINEPHRINE INJECTABLE/INTRAMUSCULAR, SUBCUTANEOUS EQ 0.3MG per DELIVERY
020800/002 TWINJECT 0.15 EPINEPHRINE INJECTABLE/INTRAMUSCULAR, SUBCUTANEOUS EQ 0.15MG per DELIVERY
020800/003 ADRENACLICK EPINEPHRINE INJECTABLE/INTRAMUSCULAR, SUBCUTANEOUS EQ 0.15MG per DELIVERY
020800/004 ADRENACLICK EPINEPHRINE INJECTABLE/INTRAMUSCULAR, SUBCUTANEOUS EQ 0.3MG per DELIVERY
087907/001 EPINEPHRINE EPINEPHRINE AEROSOL, METERED/INHALATION 0.2MG per INH
201739/001 AUVI-Q EPINEPHRINE INJECTABLE/INTRAMUSCULAR, SUBCUTANEOUS EQ 0.3MG per DELIVERY
201739/002 AUVI-Q EPINEPHRINE INJECTABLE/INTRAMUSCULAR, SUBCUTANEOUS EQ 0.15MG per DELIVERY
204200/001 ADRENALIN EPINEPHRINE INJECTABLE/INTRAMUSCULAR, INTRAOCULAR, SUBCUTANEOUS EQ 1MG BASE per ML (EQ 1MG BASE per ML)
204640/001 ADRENALIN EPINEPHRINE INJECTABLE/INTRAMUSCULAR, SUBCUTANEOUS EQ 30MG BASE per 30ML (EQ 1MG BASE per ML)
205029/001 EPINEPHRINE EPINEPHRINE SOLUTION/IV (INFUSION), INTRAOCULAR, INTRAMUSCULAR, SUBCUTANEOUS EQ 1MG BASE per ML (EQ 1MG BASE per ML)
207534/001 SYMJEPI EPINEPHRINE SOLUTION/INTRAMUSCULAR, SUBCUTANEOUS 0.3MG per ML (0.3MG per ML)

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