Application Information

This drug has been submitted to the FDA under the reference 020706/001.

Names and composition

"EMADINE" is the commercial name of a drug composed of EMEDASTINE DIFUMARATE.


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Answered questions

My eye(s) itch, are red, and have yellow goo, what is wrong?
Prior to August 2006 (last summer/fall), I never had any major sinus problems that involved my eyes. Mucous in the nose, chest etc, yes, but not anywhere else. But I'm visiting my mom last August, I'm wearing contact lenses at the time. My left eye itches, I rub it, and within minutes, it has swollen up... Asked by Cheyenne Majewski 1 year ago.

Prior to August 2006 (last summer/fall), I never had any major sinus problems that involved my eyes. Mucous in the nose, chest etc, yes, but not anywhere else. But I'm visiting my mom last August, I'm wearing contact lenses at the time. My left eye itches, I rub it, and within minutes, it has swollen up like a marble. Then at random times, I have build up that I have to remove with a Q-tip(looks like string cheese!) from the eye. I stopped having the problem back in April, but now it has resurfaced. I recently had a contact lense examination, but the doctor found nothing out of the ordinary, but I neglected to mention this at the time. The builld up/mucous isn't excessive, but is annoying. Have I got problem on my hands or a new allergy that's going to rear its ugly head every fall until I'm 60 years old? Answered by Johana Stemple 1 year ago.

Why are the eyes an easy target for allergies? When you open your eyes, the conjunctiva becomes directly exposed to the environment without the help of a filtering system such as the cilia, the hairs commonly found in the nose. People who are susceptible to allergic eye disease are those with a history of allergic rhinitis and atopic dermatitis and those with a strong family and/or personal history of allergy. Symptoms usually appear before the age of 30. The scenario for developing allergy symptoms is much the same for the eyes as that for the nose. Allergens cause the allergy antibody, IgE, to coat numerous mast cells in the conjunctiva. Upon reexposure to the allergen, the mast cell is prompted to release histamine and other mediators. The result is itching, burning, and runny eyes that become red due to inflammation, and resulting congestion. The eyelids may swell, even to the point of closing altogether. Sometimes, the conjunctiva swells with fluid and protrudes from the surface of the eye, resembling a "hive" on the eye. These reactions may also induce light sensitivity. Typically, both eyes are affected by an allergic reaction. Occasionally, only one eye is involved, particularly when only one eye is rubbed with an allergen. Allergic conjunctivitis is inflammation of the conjunctiva that is caused by a reaction to allergens. The inflammation causes enlargement of the blood vessels in the conjunctiva ("congestion"), resulting in a red, or blood- shot appearance of the eyes. How do we care for allergic eyes? Most people with eye allergies treat themselves and do so quite effectively with OTC products. If these remedies are not working or if there is eye pain, extreme redness, or heavy discharge, you should seek medical advice. Some conditions, for example, are serious with potential sight-threatening complications if needed treatment is delayed. Avoid the Triggers Avoidance is once again the cornerstone of allergy treatment. It is particularly important to avoid both airborne and contact allergens. Remember, rubbing your eyes is a physical trigger and therefore must be avoided. Topical Antihistamines & Decongestants Antihistamine eye drops work by blocking histamine receptors in the conjunctiva. The histamine, therefore, is unable to attach to the conjunctiva. They are effective in relieving itching, but have little impact on swelling or redness. They have two advantages over antihistamine tablets; there is a quicker onset of action and less drying of the eye. The new generation of topical antihistamines includes Emadine (emedastine difumarate) and Livostin (levocabastine). The side effects of these medications include mild stinging and burning of the eyes upon use, headaches, and sleepiness. Decongestants take the redness away as advertised. However, they do not help relieve itching. They act by shrinking the blood vessels on the conjunctiva. (They are not really effective against allergic eyes.) The decongestants, Visine LR (oxymetazdine) and Visine Original (tetrahydrozoline hydrochloride), are available OTC. They do have a potential for abuse and should not be used by persons with narrow angle glaucoma, an eye disease featuring elevated pressure within the eye. Allergy Assist The prolonged use of decongestant nasal sprays can produce a rebound phenomenon, in which the medication begins to cause more congestion than it relieves. This phenomenon rarely occurs in the eyes with the repeated use of decongestant drops. The mucous membranes of the eye are different from those of the nose. The eyes can become irrit8ated and less responsive to the drops, but unlike the nose, the eyes tend not to develop "rebound" redness. Combination antihistamine-decongestant preparations can provide quick relief that lasts a few hours. They lessen the itch, redness and swelling and are very useful for milder symptoms. Common combinations include Naphcon A or Opcon A (pheniramine with naphcyoline hydrochloride) and Vasocon A (antazoline with naphaydine). Side effects are minimal, but the drops may become less effective if used for prolonged periods. They do have a potential for abuse and should not be used by persons with narrow angle glaucoma. Answered by Cheree Schmiege 1 year ago.

yes you do have a problem on your hands. I mean that literally. you see, what you have is a severe contact lens infection. caused by improper cleansing of the lens, soft contact lens wearers, and the type of solution you are using. your condition is called (microbial keratitis) a doctor cannot help you. the kind of physician you need to see is an ophthalmologist. sometimes when ppl. who wear contact lens clean their Len's, they do it improperly. instead of just running them through the water,you rub the solution into the lens and massage both sides. then rinse. its called the rub and rinse method. store this in your memory for future use. and see a ophthalmologist as soon as you can. b-4 you damage your cornea to the point of blindness, or replacement surgery. Answered by Kindra Mullinex 1 year ago.

I sounds Like Conjunctivitis not serious but rather annoying. You should go to your doctor because if it is someting more serious it can cause you problems Answered by Olive Hesby 1 year ago.

it might be pink-eye or a random allergy. I think you ought to see the doc to be really sure about it. Answered by Dino Cabreros 1 year ago.

maybe you have pink-eye. (and it's highly contagious). I would keep the contacts out, otherwise, you are going to make it worse ! Answered by Shoshana Farguharson 1 year ago.

it sounds like conjunctivitis. See your doctor, they will give you something to clear it up. Answered by Dagmar Rastogi 1 year ago.

HELP !! I have this white small bump inside my eyelid. I'll rate you 5 stars!?
It's freaking me out because this is probably the 4th time I get it. At first I thought it was the brand of mascara I used so I threw that away but it's come back! It's not painful but it feels like I have hair or sand in my eyes so it causes discomfort. I've also googled and it keeps saying... Asked by Billy Faller 1 year ago.

I get those darn white things all the time! its just allergies!! my eyes occasionally start to itch and , as you said, i feel like i have a rock in my eye and when i go look at it in the mirror i see that thing. I use Emadine eye drops against allergies and the itching stops and the bump disappears after a little while. Sometimes i even notice i have the bum thingy although i wouldn't be feeling anything. I get hay fever too so they are normally linked cos of allergies. & stop throwing away makeup! they got nothing to do with it :P Answered by Nigel Hornish 1 year ago.

What are good allergy perscription drugs that are over the counter now?
thanks. I usually go to the doctor but can't get there right now. I take Allegra D but can't get the eye drops that are usually given to me there as well as the nasal spray, which was Rhinocort Asked by Lurlene Zirk 1 year ago.

Oral antihistamine should work as good as eyedrops or nasal sprays, sticking to what you took before would be the safest, up the dose to the maximum suggested daily dose if you have to. If your allergies cannot be resolved by your previous medications, see a doctor. DO NOT TAKE MULTIPLE ANTIHISTAMINES AT THE SAME TIME. If you've never used a nose spray or eyedrop antihistamine before, you should ask a doctor and maybe try out the prescription versions of those drugs (eyedrop: Emadine and Livostin; nose spray: Astelin.) there is one over-the-counter eyedrop called Ocu-Hist, but it is not one of the take your call. Answered by Mariann Stow 1 year ago.

There are LOTS of eye drops that are for allergy-eyes. Just read the front of the box. It will tell you. If you MUST use something for your nose, use ONLY SALINE spray OR use a sinus wash. Answered by Renetta Kottwitz 1 year ago.

Everything over the counter is just temporary I have bad allergies as well and I've just learned to deal with them. If your dealing with kids all day get drunk before you go to work but try not to get caught hahahahaha! Answered by Fernanda Dalziel 1 year ago.

If you have nasal allergies, me, personally, I swear by SinuFix. Homeopathic. All natural. Sold at the Vitamin Store, or online Nasalcrom is also very good. Both work progressively. You need patience. Answered by Yanira Fobbs 1 year ago.

Zyrtec is pretty good. Answered by Tonita Kretzer 1 year ago.

What medicine would you recommend for hardcore allergies?
I am allergic to cats,dogs,and horses causes me to sneeze and wheeze. Every medication I tried doesn't work and I cant take being sick 24/7 my head might blow off.Any recommendation's? Asked by Reid Durall 1 year ago.

There are over the counter medicines such as Benadryl, Zyrtec, Claritin, and newly otc Allegra (which used to be prescription). But if they are as severe as you say, you should see a doctor and they can provide a prescription. There are much stronger medicines that aren't over the counter and insurance usually picks up on these. Some prescription medications are Claritin, Xyzal, Astelin, Emadine and Livostin. It is best to either see a pharmacist about the over the counter medications, or set up an appointment with your doctor so they can see what works best with your system and won't counteract with the other medicines you're on. Answered by Sebrina Desha 1 year ago.

If you're THAT badly off, you need to see an allergist and get shots or alternative treatments besides pills. You'll end up with allergic asthma or worse if not. Until then, I suggest stacking multiple antihistamines. I keep 3 on hand: loratadine (claritin), ceterizine (zyrtec), and ketotifen (zaditor) eye drops. I usually take one zyrtec and one claritin daily and apply the eye drops when needed (usually around cats or during cedar or ragweed season). You can also add diphenhydramine for night time if needed. Xyzal (zei-zahl) is good, too, but you need a prescription for that. Answered by Alia Reuven 1 year ago.

you need to not be allergic to the therapy on condition that those drugs have the allergies in them that make the antibiotic artwork.(Scientist concept is to make your bodies have extra of the illness so it will get used to it and conflict it off much less complicated.) i might say it must be extra advantageous to now not take those hypersensitive reaction medicines for for a pair of days and attempt a added business organization as the thank you to artwork for you. Answered by Kris Callery 1 year ago.


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