Application Information

This drug has been submitted to the FDA under the reference 020336/001.

Names and composition

"DYNACIRC CR" is the commercial name of a drug composed of ISRADIPINE.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
020336/001 DYNACIRC CR ISRADIPINE TABLET, EXTENDED RELEASE/ORAL 5MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
020336/002 DYNACIRC CR ISRADIPINE TABLET, EXTENDED RELEASE/ORAL 10MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
019546/001 DYNACIRC ISRADIPINE CAPSULE/ORAL 2.5MG
019546/002 DYNACIRC ISRADIPINE CAPSULE/ORAL 5MG
020336/001 DYNACIRC CR ISRADIPINE TABLET, EXTENDED RELEASE/ORAL 5MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
020336/002 DYNACIRC CR ISRADIPINE TABLET, EXTENDED RELEASE/ORAL 10MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
077169/001 ISRADIPINE ISRADIPINE CAPSULE/ORAL 2.5MG
077169/002 ISRADIPINE ISRADIPINE CAPSULE/ORAL 5MG
077317/001 ISRADIPINE ISRADIPINE CAPSULE/ORAL 2.5MG
077317/002 ISRADIPINE ISRADIPINE CAPSULE/ORAL 5MG
201067/001 ISRADIPINE ISRADIPINE TABLET, EXTENDED RELEASE/ORAL 5MG
201067/002 ISRADIPINE ISRADIPINE TABLET, EXTENDED RELEASE/ORAL 10MG

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Answered questions

Can you explaine what these medications are for?
(Just few detail to know why a person is taking them.) Hydrochlothiazide 25mg (ivax) Enalaphil Maleate SMG TA Simvastatin 10 mg Tablet Dynacirc CR 10 MGTablet SA Asked by Marti Konrad 1 year ago.

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Enalapril is used for treating high blood pressure Simvastatin is used for lowering blood cholesterol levels DynaCirc CR is used for treating high blood pressure. This medicine may be used alone on in combination with other high blood pressure medications Someone is trying to prevent a heart attack and/or stroke with these medications Answered by Kieth Rapoza 1 year ago.

The first is a dieuretic. Taken by people with high blood pressure, certain types of obsesity. It rids the body of water weight or fluid retension. It has to be taken in conjunction with a Potassium salt to prevent dehydration and loss of electrolytes. Second is a blood pressure mediation that also increases natural postassium. Looks like a medication routine for someone with High Blood pressure from Hyptertension Thirs lowers lipids and is used in Choelsterold managmeent. That last is Isradipine, another high blood pressure medicine. I would say you have a somewhat bloated or over weight, probabaly older person (50+) who is being treated for high blood pressure and water weight retension. It's a common regiment. It can be done with 3 medications not four. But I didn't notice a potassium pill so the Enalaphil might be used to help raise the Potassium content. You have a person with high blood pressure who has too high a cholesterol rating and is probably over weight and is vastly becoming a candidate for a heart attack and will be prone to diabetes and may already be type one diabetic. That is common in this class of persson. They need to go on a contrtolled diet and reduce sugar, table salt and bad animals fats. Broiled skinless chicken, unsalted (you can try a little pepper, some lemon or onions to make it taste right), broccolli, salad with apple cider or red wine vinegar and maybe a tad of olive oil, but I'd consutl the physican on that one. Decafe coffee no sugar. Use some creamer it has small amoutns of sugar in it. Grape fruit for breakfast. HAve a whole one, no sugar. Apples, a nice natural sugar, anti-oxident. Get off the burgers, get off the Color Sanders cool it with potatoes for a while. Consult with doctor for caloric consumpion. More than likly this person is currently consuming over 3,000 calories a day, possible as much as 4,000 and this person should really be in a 2,400 range and attempt to get that down to 2,100 optimually. A diet for this person would be maybe 2,500 calories a day. But I'd have see they're size to say otherwise. That means no sodas, no sugar. Oatmeal for breakfast with some rasins maybe a tad of honey, no more than a tad. Whole grain toast with some nice peanut butter, not a lot. Grapefruit, whole or canned NO sugar. Lunch chicken breast, half or whole, skinnelss, broiled or poached. Salad with vinegerette dressing, as large a salad as you'd like. Maybe put the chicken in it. No salt. Snacks an apple anytime you're hungery. Go ahead eat 5 a day they are almsot a pound and very healthy for the body, but I'd brush my teeth afterwards. Dinner, natural fruit salad, water melon, catnalope, honeyduew, grapefruit, apples. Or another chicken breast, broccoli or asperagus no salt, no butter use lemon, orange some pepper, some garlic, some onlion to make it taste good. Eat early, not later that 7 pm. That's a big diet, but this is a big person. It a lot less than they were eating before. Healthier. This person is a double quaterpounder large fries a chocoalte shake or large coke twice a day, candy bar, ice cream, chocolate cake person That's speculation of course. But the High Blood Pressure, Dieretic and Anti-Choelsterol regiment paints a picture of someone who is heading for an early grave if they don't re-think their life style AND they should conslt on all of this with a doctor. They re-write their life style (and you can have many things to eat you can enjoy, just no more atrtrificailly sugar and flour things or salty foods) they can extend their life by a decade or more. IF your Doctor PERMITS and this is a MUST you can start using a small amount of POTASSIUM BASED TABLE SALT. SMALL amounts and ONLY if the DOCTOR agrees. Throw your Sodium salt out. I have always viewed that Salt and Sugar should be restricted drugs only available by prescription. Answered by Sidney Olano 1 year ago.

I'm assuming you had a few typos in your question. Hydrochlorothiazide is a diuretic, Enalapril is an angiotensin converting enzyme inhibitor and Dynacirc is a calcium channel blocker. All of these are used for the treatment of high blood pressure. Simvastatin is an enzyme inhibitor used to lower cholesterol levels. Answered by Allan Campanaro 1 year ago.

I agree 100% with SeanT. but would like to add that people with heart problems (esp. high blood pressure) take diuretics to remove some of the water from the body, which in turn lessens the work of the heart. High blood pressure meds and diuretics go hand in hand. Answered by Myrtice Dankert 1 year ago.


What are some side effects to Dynocirc CR medication?
Asked by Dan Sangiacomo 1 year ago.

DynaCirc (note spelling) (isradipine) has a number of adverse effects such as headache, dizziness, light-headedness, flushing (warm feeling), fast heartbeat, fatigue, stomach upset, vomiting and diarrhea. These are usually transitory but if they persist they should be reported to your prescriber. The potentially life-threatening adverse effects are chest pain, swelling of the face, eyes, lips, tongue, arms or legs, difficulty breathing or swallowing, fainting or rash should be reported immediately to your prescriber. Answered by Johnathon Ruggle 1 year ago.


Does AMLODIPINE has the same symptom like Parkinson? I feel I am getting slow motion since I am taking this BP?
I have been told I have Parkinson, but I don't have any symptom of Parkinson except I walk slow motion & this happened since I am taking AMLODIPINE BP medicine starting 2 years ago. Anyone knows if they are related. Thanks! Bina Asked by Margarett Desanto 1 year ago.

Parkinson's doesn't make you walk in slo-mo, neither does your bp med. I take the same kind. Bina did not indicate it was being taken for Parkinson's and it is not indicated as a treatment for Parkinson's, so I don't know why it would be prescribed for your husband's condition. It is a CCB and is used for high bp and angina... Amlodipine Oral is used to treat the following: High Blood Pressure, Type of Angina Where Chest Pain Occurs at Rest, A Continuous Squeezing Pain in the Chest, Slow Progression of Disease of the Arteries of the Heart Amlodipine Oral may also be used to treat: Angina As I said, I take it for bp. Answered by Delisa Souser 1 year ago.

Two girls with luscious lips seductively kissing and tenderly nibbling each others tongues teasingly as they frollick with sl*tty abandonment . Pass me the kleenex Answered by Pete Grotz 1 year ago.


My mother has dementia and parkinsons like symtoms. She chokes on ensure fed with a sringe, Help, ideas????
I have been helping my father take care of my mom for going on nine years. But recently she wasnt eating the fruit smoothies, mashed potatoes and liquified vegies , I have been feeding her smoothies with cottage cheese, fruit, protien powder yummm. Today she is having trouble taking any thing even ensure alone... Asked by Elvina Ranildi 1 year ago.

I have been helping my father take care of my mom for going on nine years. But recently she wasnt eating the fruit smoothies, mashed potatoes and liquified vegies , I have been feeding her smoothies with cottage cheese, fruit, protien powder yummm. Today she is having trouble taking any thing even ensure alone with a sringe. So much choking and spiting ,hard to tell how much she is really consuming Help!!!!!!!! feeding tube very last alternative. Answered by Eugene Waide 1 year ago.

I would totally let someone else breastfeed my kid! I hate pumping and if I could get away with not doing it then awesome! Wet nursing is a very normal practice and would be quite routine in the world if we didn't have formula. How else would some babies be fed if we didn't have formula and the mother was not able to nurse? Also, high class women would have wet nurses to take care of their children for them back in the day. In more remote places, women take turns caring for the children while the others gather food (women bring home 70% of the bacon in hunter/gatherer societies) and certainly some wet nursing occurs there. I wouldn't be worried about bonding, baby only has one mommy who does so many more things than just breast feed. I just want you to know that it is a very normal thing in many parts of the world. I am not seeing anything wrong with it other than personal preference. Answered by Abram Merenda 1 year ago.


Embryonic stem cells and Parkinson's disease?
Why are embryonic stem cells an effective treatment for Parkinson's disease? What makes them better than say deep brain stimulation or dopamine enhancing drugs such as Levodopa? Thanks Asked by Zoraida Boon 1 year ago.

Stem cellular treatment would not treatment Alzheimer's disease or Parkinson's disease. Stem cells are injected interior the wish that they are going to enhance and multiply into new strategies cells whilst used to handle those 2 circumstances. It would not continuously artwork yet on the different hand it would not continuously fail. With some fulfillment a man or woman can see an progression of their condition however the underlying disease technique maintains unabated. there is a few thought that if the disease is genetic, that a man or woman's very own cells could artwork against them as those new cells could be comparable to the cells that are being replaced and that they, too, could be vendors to the disease technique. although in the present day it incredibly is oftentimes hypothesis. greater fulfillment has been executed with Parkinson's disease by using stem cellular transplants because of the fact the only subject curiously incorrect in this condition is lacking Dopamine producing neurons, the reason of their terminating heavily isn't understood. Alzheimer's disease is a much greater complicated condition which includes protein plaques deposits which choke off neurons. without with the flexibility to get rid of those plaques any new cells that could desire to be inspired to enhance would not final long or be of lots earnings. Answered by Coleman Defrancis 1 year ago.

The Parkinson's Reversing Breakthrough? Answered by Karlyn Osterfeld 1 year ago.

I'm not an expert but I was under the impression that just about every stem cell treatment uses adult stem cells, not embryonic cells. Embryonic stem cells have been used mainly in research so far I believe. Answered by Darius Strohmayer 1 year ago.


Mother suffering from Parkinson ism could not walk Or tho. Doctor help her?
Asked by Romelia Branham 1 year ago.

A team of researchers at Northwestern University have found in a new study that the blood pressure drug isradipine slowed down the progress of Parkinson's disease in genetically altered lab mice, and in some cases prevented it from occurring. Isradipine is commonly prescribed to patients to treat hypertension (high blood pressure) and to prevent a stroke. The researchers, led by Professor D. James Surmeier, found the drug rejuvenates aging dopamine cells, whose death in the brain causes the symptoms of the disease; dopamine is a critical chemical messenger in the brain that affects a person's ability to direct his movements. Parkinson's disease is fatal and there is at present no cure for it. Dr. Surmeier says they hope the drug will protect dopamine neurons, so that if taken early enough, it will prevent Parkinson's disease, even in those at risk. Surmeier says isradipine could be taken in much the same way as aspirin is taken to protect the heart and might also significantly benefit people who already have Parkinson's disease. Surmeier's team found that the drug protected dopamine neurons from toxins that would normally kill them by restoring the neurons to a younger state in which they are less vulnerable. Further research plans to test the drug on humans. Parkinson's disease is the second leading degenerative brain disease in the United States, effecting more than 1 million people. Dr. D. James Surmeier is the Nathan Smith Davis Professor and chair of physiology at Northwestern University's Feinberg School of Medicine. Answered by Andrew Sporer 1 year ago.

Please ignore Hailey he hasn't a clue what he's talking about. With a condition like Parkinson's disease only a doctor can treat it, and I'm sure your mother's doctor is looking after her. Good luck. Answered by Rosy Koscinski 1 year ago.

drugs seldom help. There are protocols that help most conditions. Answered by Destiny Schwandt 1 year ago.


Can you explaine what these medications are for?
(Just few detail to know why a person is taking them.) Hydrochlothiazide 25mg (ivax) Enalaphil Maleate SMG TA Simvastatin 10 mg Tablet Dynacirc CR 10 MGTablet SA Asked by Odell Ehrenberg 1 year ago.

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Enalapril is used for treating high blood pressure Simvastatin is used for lowering blood cholesterol levels DynaCirc CR is used for treating high blood pressure. This medicine may be used alone on in combination with other high blood pressure medications Someone is trying to prevent a heart attack and/or stroke with these medications Answered by Maryalice Toudle 1 year ago.

The first is a dieuretic. Taken by people with high blood pressure, certain types of obsesity. It rids the body of water weight or fluid retension. It has to be taken in conjunction with a Potassium salt to prevent dehydration and loss of electrolytes. Second is a blood pressure mediation that also increases natural postassium. Looks like a medication routine for someone with High Blood pressure from Hyptertension Thirs lowers lipids and is used in Choelsterold managmeent. That last is Isradipine, another high blood pressure medicine. I would say you have a somewhat bloated or over weight, probabaly older person (50+) who is being treated for high blood pressure and water weight retension. It's a common regiment. It can be done with 3 medications not four. But I didn't notice a potassium pill so the Enalaphil might be used to help raise the Potassium content. You have a person with high blood pressure who has too high a cholesterol rating and is probably over weight and is vastly becoming a candidate for a heart attack and will be prone to diabetes and may already be type one diabetic. That is common in this class of persson. They need to go on a contrtolled diet and reduce sugar, table salt and bad animals fats. Broiled skinless chicken, unsalted (you can try a little pepper, some lemon or onions to make it taste right), broccolli, salad with apple cider or red wine vinegar and maybe a tad of olive oil, but I'd consutl the physican on that one. Decafe coffee no sugar. Use some creamer it has small amoutns of sugar in it. Grape fruit for breakfast. HAve a whole one, no sugar. Apples, a nice natural sugar, anti-oxident. Get off the burgers, get off the Color Sanders cool it with potatoes for a while. Consult with doctor for caloric consumpion. More than likly this person is currently consuming over 3,000 calories a day, possible as much as 4,000 and this person should really be in a 2,400 range and attempt to get that down to 2,100 optimually. A diet for this person would be maybe 2,500 calories a day. But I'd have see they're size to say otherwise. That means no sodas, no sugar. Oatmeal for breakfast with some rasins maybe a tad of honey, no more than a tad. Whole grain toast with some nice peanut butter, not a lot. Grapefruit, whole or canned NO sugar. Lunch chicken breast, half or whole, skinnelss, broiled or poached. Salad with vinegerette dressing, as large a salad as you'd like. Maybe put the chicken in it. No salt. Snacks an apple anytime you're hungery. Go ahead eat 5 a day they are almsot a pound and very healthy for the body, but I'd brush my teeth afterwards. Dinner, natural fruit salad, water melon, catnalope, honeyduew, grapefruit, apples. Or another chicken breast, broccoli or asperagus no salt, no butter use lemon, orange some pepper, some garlic, some onlion to make it taste good. Eat early, not later that 7 pm. That's a big diet, but this is a big person. It a lot less than they were eating before. Healthier. This person is a double quaterpounder large fries a chocoalte shake or large coke twice a day, candy bar, ice cream, chocolate cake person That's speculation of course. But the High Blood Pressure, Dieretic and Anti-Choelsterol regiment paints a picture of someone who is heading for an early grave if they don't re-think their life style AND they should conslt on all of this with a doctor. They re-write their life style (and you can have many things to eat you can enjoy, just no more atrtrificailly sugar and flour things or salty foods) they can extend their life by a decade or more. IF your Doctor PERMITS and this is a MUST you can start using a small amount of POTASSIUM BASED TABLE SALT. SMALL amounts and ONLY if the DOCTOR agrees. Throw your Sodium salt out. I have always viewed that Salt and Sugar should be restricted drugs only available by prescription. Answered by Javier Salvato 1 year ago.

I'm assuming you had a few typos in your question. Hydrochlorothiazide is a diuretic, Enalapril is an angiotensin converting enzyme inhibitor and Dynacirc is a calcium channel blocker. All of these are used for the treatment of high blood pressure. Simvastatin is an enzyme inhibitor used to lower cholesterol levels. Answered by Margot Everton 1 year ago.

I agree 100% with SeanT. but would like to add that people with heart problems (esp. high blood pressure) take diuretics to remove some of the water from the body, which in turn lessens the work of the heart. High blood pressure meds and diuretics go hand in hand. Answered by Billye Albarazi 1 year ago.


What are some side effects to Dynocirc CR medication?
Asked by Cruz Minish 1 year ago.

DynaCirc (note spelling) (isradipine) has a number of adverse effects such as headache, dizziness, light-headedness, flushing (warm feeling), fast heartbeat, fatigue, stomach upset, vomiting and diarrhea. These are usually transitory but if they persist they should be reported to your prescriber. The potentially life-threatening adverse effects are chest pain, swelling of the face, eyes, lips, tongue, arms or legs, difficulty breathing or swallowing, fainting or rash should be reported immediately to your prescriber. Answered by Carey Ellerbee 1 year ago.


Does AMLODIPINE has the same symptom like Parkinson? I feel I am getting slow motion since I am taking this BP?
I have been told I have Parkinson, but I don't have any symptom of Parkinson except I walk slow motion & this happened since I am taking AMLODIPINE BP medicine starting 2 years ago. Anyone knows if they are related. Thanks! Bina Asked by Lesia Khatib 1 year ago.

Parkinson's doesn't make you walk in slo-mo, neither does your bp med. I take the same kind. Bina did not indicate it was being taken for Parkinson's and it is not indicated as a treatment for Parkinson's, so I don't know why it would be prescribed for your husband's condition. It is a CCB and is used for high bp and angina... Amlodipine Oral is used to treat the following: High Blood Pressure, Type of Angina Where Chest Pain Occurs at Rest, A Continuous Squeezing Pain in the Chest, Slow Progression of Disease of the Arteries of the Heart Amlodipine Oral may also be used to treat: Angina As I said, I take it for bp. Answered by Lane Hauke 1 year ago.

Two girls with luscious lips seductively kissing and tenderly nibbling each others tongues teasingly as they frollick with sl*tty abandonment . Pass me the kleenex Answered by Joey Asebedo 1 year ago.


My mother has dementia and parkinsons like symtoms. She chokes on ensure fed with a sringe, Help, ideas????
I have been helping my father take care of my mom for going on nine years. But recently she wasnt eating the fruit smoothies, mashed potatoes and liquified vegies , I have been feeding her smoothies with cottage cheese, fruit, protien powder yummm. Today she is having trouble taking any thing even ensure alone... Asked by Venus Pavlick 1 year ago.

I have been helping my father take care of my mom for going on nine years. But recently she wasnt eating the fruit smoothies, mashed potatoes and liquified vegies , I have been feeding her smoothies with cottage cheese, fruit, protien powder yummm. Today she is having trouble taking any thing even ensure alone with a sringe. So much choking and spiting ,hard to tell how much she is really consuming Help!!!!!!!! feeding tube very last alternative. Answered by Melida Crapanzano 1 year ago.

I would totally let someone else breastfeed my kid! I hate pumping and if I could get away with not doing it then awesome! Wet nursing is a very normal practice and would be quite routine in the world if we didn't have formula. How else would some babies be fed if we didn't have formula and the mother was not able to nurse? Also, high class women would have wet nurses to take care of their children for them back in the day. In more remote places, women take turns caring for the children while the others gather food (women bring home 70% of the bacon in hunter/gatherer societies) and certainly some wet nursing occurs there. I wouldn't be worried about bonding, baby only has one mommy who does so many more things than just breast feed. I just want you to know that it is a very normal thing in many parts of the world. I am not seeing anything wrong with it other than personal preference. Answered by Ema Turrigiano 1 year ago.


Embryonic stem cells and Parkinson's disease?
Why are embryonic stem cells an effective treatment for Parkinson's disease? What makes them better than say deep brain stimulation or dopamine enhancing drugs such as Levodopa? Thanks Asked by Gregg Kowalewski 1 year ago.

Stem cellular treatment would not treatment Alzheimer's disease or Parkinson's disease. Stem cells are injected interior the wish that they are going to enhance and multiply into new strategies cells whilst used to handle those 2 circumstances. It would not continuously artwork yet on the different hand it would not continuously fail. With some fulfillment a man or woman can see an progression of their condition however the underlying disease technique maintains unabated. there is a few thought that if the disease is genetic, that a man or woman's very own cells could artwork against them as those new cells could be comparable to the cells that are being replaced and that they, too, could be vendors to the disease technique. although in the present day it incredibly is oftentimes hypothesis. greater fulfillment has been executed with Parkinson's disease by using stem cellular transplants because of the fact the only subject curiously incorrect in this condition is lacking Dopamine producing neurons, the reason of their terminating heavily isn't understood. Alzheimer's disease is a much greater complicated condition which includes protein plaques deposits which choke off neurons. without with the flexibility to get rid of those plaques any new cells that could desire to be inspired to enhance would not final long or be of lots earnings. Answered by Hiroko Munuz 1 year ago.

The Parkinson's Reversing Breakthrough? Answered by Judith Rix 1 year ago.

I'm not an expert but I was under the impression that just about every stem cell treatment uses adult stem cells, not embryonic cells. Embryonic stem cells have been used mainly in research so far I believe. Answered by Amalia Vu 1 year ago.


Mother suffering from Parkinson ism could not walk Or tho. Doctor help her?
Asked by Emma Fioranelli 1 year ago.

A team of researchers at Northwestern University have found in a new study that the blood pressure drug isradipine slowed down the progress of Parkinson's disease in genetically altered lab mice, and in some cases prevented it from occurring. Isradipine is commonly prescribed to patients to treat hypertension (high blood pressure) and to prevent a stroke. The researchers, led by Professor D. James Surmeier, found the drug rejuvenates aging dopamine cells, whose death in the brain causes the symptoms of the disease; dopamine is a critical chemical messenger in the brain that affects a person's ability to direct his movements. Parkinson's disease is fatal and there is at present no cure for it. Dr. Surmeier says they hope the drug will protect dopamine neurons, so that if taken early enough, it will prevent Parkinson's disease, even in those at risk. Surmeier says isradipine could be taken in much the same way as aspirin is taken to protect the heart and might also significantly benefit people who already have Parkinson's disease. Surmeier's team found that the drug protected dopamine neurons from toxins that would normally kill them by restoring the neurons to a younger state in which they are less vulnerable. Further research plans to test the drug on humans. Parkinson's disease is the second leading degenerative brain disease in the United States, effecting more than 1 million people. Dr. D. James Surmeier is the Nathan Smith Davis Professor and chair of physiology at Northwestern University's Feinberg School of Medicine. Answered by Veronica Veasey 1 year ago.

Please ignore Hailey he hasn't a clue what he's talking about. With a condition like Parkinson's disease only a doctor can treat it, and I'm sure your mother's doctor is looking after her. Good luck. Answered by Jonnie Langseth 1 year ago.

drugs seldom help. There are protocols that help most conditions. Answered by Ozella Mosey 1 year ago.


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