Application Information

This drug has been submitted to the FDA under the reference 084315/001.

Names and composition

"DEXAMETHASONE ACETATE" is the commercial name of a drug composed of DEXAMETHASONE ACETATE.

Answered questions

Cortisol, hydrocortisone acetate, and prenatal stress.?
I am doing some research on prenatal stress and I am having a hard time find some things out. Cortisol is secreted in response to stress. So increase in cortisol concentration will increase stress. (CORRECT ME IF I'M WRONG)I am trying to look for what exactly hydrocortisone acetate (HCA) does. I think it... Asked by Bryce Grip 6 months ago.

I am doing some research on prenatal stress and I am having a hard time find some things out. Cortisol is secreted in response to stress. So increase in cortisol concentration will increase stress. (CORRECT ME IF I'M WRONG) I am trying to look for what exactly hydrocortisone acetate (HCA) does. I think it reduces cortisol, but I'm not sure. Prenatal stress then affects the piglets psychologically and physically (this I know). Basically need help looking up relations of cortisol and stress, relation of hydrocortisone acetate and cortisol, and how hydrocortisone acetate works. It'll be great if anyone can give me some sites. Answered by Veta Duchesneau 6 months ago.

Yes, and er, not exactly. I will explain. Cortisol is not an easy hormone. Increased cortisol is called hypercortisolism, or Cushing's syndrome (or disease, if the source is pituitary). Cortisol raises naturally and has a natural rise and fall every day - called the diurnal rhythm. It wakes you up in the morning and puts you in bed at night if all is well. During times of stress, ACTH is secreted by the pituitary and more cortisol is released. Adrenaline is also released - both are in the adrenals. Actually a lot of hormones are secreted. In any case, if the stress is short lived, the cortisol should just be pretty short lived. In the case where stress is longer, such as pregnancy or illness, cortisol is raised to deal with it. It is, as long the cortisol stays within certain limits and timelines, a good thing, so that the body can reduce inflammation, keep blood pressure up, etc. If cortisol is raised too much, too long, than the body basically starts to destroy itself. It can lead to minor issues like cataracts up to major issues like depression, bone loss and death. Too much can put stress on the body. As for hydrocrotisone acetate, that is a form of corticosteroid. Taking it will not lower your cortisol but raise it. There are many forms of corticosteroids known simply as steroids such as hydrocortisone and prednisone and dexamethasone - they mainly differ in how long they last and when they kick in as well as how close they are to what the body makes. HCA is rather uncommon since it has a short life. Taking any corticosteroid has risks - if you take more than your adrenals make which is roughly 20mg of HC, then the adrenals can go on vacation - they are lazy things and takes a while to wake them up. A raise in cortisol during pregnancy is very normal. The stretch marks that are purple are a sign of this - that is a sign of Cushing's syndrome and pretty much the only time purple or colored stretch marks happen is when steroids are involved (naturally or not). I hope this helps. Answered by Charlene Gladhart 6 months ago.

My heart goes out to u girl....i havent been in ur shoes so i wudnt understand how the social phobia gets under ur skin..but i do know that its difficult to socialize with a group of friends instead of just 1 friend (some ppl may differ with that). U'v just got to pay more attention to whats being said in normal conversations instead of thinking insecure thoughts cuz thats part of where the "quiet mouse" character stems from. So just refocus ur attention in their presence. Be more aware of ur external and ignore ur internal for a while. Hope that helps short-term. Seeing a counselor is a very good and mature long term solution...and the younger u r the faster u'l heal. Answered by Caprice Colop 6 months ago.

What is the major of chemotherapy agents in anti-cancer drugs ?
Asked by Brigitte Mogensen 6 months ago.

There are many different chemotherapy agents. Different drugs work for different cancers, and they are frequently used in combination. You need to be more specific. Here is a list of chemo drugs: 13-cis-Retinoic Acid 2-CdA 2-Chlorodeoxyadenosine 5-Fluorouracil 5-FU 6-Mercaptopurine 6-MP 6-TG 6-Thioguanine Abraxane Accutane ® Actinomycin-D Adriamycin ® Adrucil ® Agrylin ® Ala-Cort ® Aldesleukin Alemtuzumab ALIMTA Alitretinoin Alkaban-AQ ® Alkeran ® All-transretinoic acid Alpha interferon Altretamine Amethopterin Amifostine Aminoglutethimide Anagrelide Anandron ® Anastrozole Arabinosylcytosine Ara-C Aranesp ® Aredia ® Arimidex ® Aromasin ® Arranon ® Arsenic trioxide Asparaginase ATRA Avastin ® Azacitidine BCG BCNU Bevacizumab Bexarotene BEXXAR ® Bicalutamide BiCNU Blenoxane ® Bleomycin Bortezomib Busulfan Busulfex ® C225 Calcium Leucovorin Campath ® Camptosar ® Camptothecin-11 Capecitabine Carac ™ Carboplatin Carmustine Carmustine wafer Casodex ® CC-5013 CCNU CDDP CeeNU Cerubidine ® Cetuximab Chlorambucil Cisplatin Citrovorum Factor Cladribine Cortisone Cosmegen ® CPT-11 Cyclophosphamide Cytadren ® Cytarabine Cytarabine liposomal Cytosar-U ® Cytoxan ® Dacarbazine Dacogen Dactinomycin Darbepoetin alfa Daunomycin Daunorubicin Daunorubicin hydrochloride Daunorubicin liposomal DaunoXome ® Decadron Decitabine Delta-Cortef ® Deltasone ® Denileukin diftitox DepoCyt ™ Dexamethasone Dexamethasone acetate Dexamethasone Sodium Phosphate Dexasone Dexrazoxane DHAD DIC Diodex Docetaxel Doxil ® Doxorubicin Doxorubicin liposomal Droxia ™ DTIC DTIC-Dome ® Duralone ® Efudex ® Eligard ™ Ellence ™ Eloxatin ™ Elspar ® Emcyt ® Epirubicin Epoetin alfa Erbitux ™ Erlotinib Erwinia L-asparaginase Estramustine Ethyol Etopophos ® Etoposide Etoposide Phosphate Eulexin ® Evista ® Exemestane Fareston ® Faslodex ® Femara ® Filgrastim Floxuridine Fludara ® Fludarabine Fluoroplex ® Fluorouracil Fluorouracil (cream) Fluoxymesterone Flutamide Folinic Acid FUDR ® Fulvestrant G-CSF Gefitinib Gemcitabine Gemtuzumab ozogamicin Gemzar ® GleevecTM Gliadel wafer (t) GM-CSF Goserelin granulocyte - colony stimulating factor (t) Granulocyte macrophage colony stimulating factor (o) Halotestin (t) Herceptin (t) Hexadrol (t) Hexalen (t) Hexamethylmelamine (t) HMM (t) Hycamtin (t) Hydrea (t) Hydrocort Acetate (t) Hydrocortisone Hydrocortisone sodium phosphate Hydrocortisone sodium succinate Hydrocortone phosphate (t) Hydroxyurea Ibritumomab Ibritumomab Tiuxetan Idamycin ® Idarubicin Ifex ® IFN-alpha Ifosfamide IL-11 IL-2 Imatinib mesylate Imidazole Carboxamide Interferon alfa Interferon Alfa-2b (PEG conjugate) (o) Interleukin - 2 (t) Interleukin-11 (o) Intron A® (interferon alfa-2b) Iressa ® Irinotecan Isotretinoin Kidrolase (t) Lanacort (t) L-asparaginase (t) LCR (o) Lenalidomide Letrozole Leucovorin Leukeran (t) Leukine (t) Leuprolide Leurocristine (o) Leustatin (t) Liposomal Ara-C (t) Liquid Pred (t) Lomustine L-PAM (o) L-Sarcolysin (o) Lupron (t) Lupron Depot ® Matulane (t) Maxidex (t) Mechlorethamine Mechlorethamine Hydrochloride Medralone (t) Medrol ® Megace (t) Megestrol Megestrol Acetate (o) Melphalan Mercaptopurine Mesna Mesnex (t) Methotrexate Methotrexate Sodium (o) Methylprednisolone Meticorten (t) Mitomycin Mitomycin-C (o) Mitoxantrone M-Prednisol (t) MTC (o) MTX (o) Mustargen (t) Mustine Mutamycin (t) Myleran (t) Mylocel (t) Mylotarg (t) Navelbine ® Nelarabine Neosar (t) Neulasta (t) Neumega (t) Neupogen ® Nexavar ® Nilandron (t) Nilutamide Nipent ® Nitrogen Mustard (o) Novaldex (t) Novantrone (t) Octreotide Octreotide acetate (o) Oncospar (t) Oncovin (t) Ontak (t) Onxal (t) Oprevelkin Orapred (t) Orasone (t) Oxaliplatin Paclitaxel Paclitaxel Protein-bound Pamidronate Panretin (t) Paraplatin (t) Pediapred (t) PEG Interferon Pegaspargase Pegfilgrastim PEG-INTRON (t) PEG-L-asparaginase PEMETREXED Pentostatin Phenylalanine Mustard (o) Platinol (t) Platinol-AQ (t) Prednisolone Prednisone Prelone (t) Procarbazine PROCRIT ® Proleukin (t) Prolifeprospan 20 with Carmustine implant (t) Purinethol ® Raloxifene Revlimid ® Rheumatrex (t) Rituxan (t) Rituximab Roferon-A® (interferon alfa-2a) Rubex (t) Rubidomycin hydrochloride (t) Sandostatin ® Sandostatin LAR (t) Sargramostim Solu-Cortef (t) Solu-Medrol (t) Sorafenib STI-571 Streptozocin SU11248 Sunitinib Sutent ® Tamoxifen Tarceva ® Targretin (t) Taxol ® Taxotere ® Temodar ® Temozolomide Teniposide TESPA (o) Thalidomide Thalomid ® TheraCys (t) Thioguanine Thioguanine Tabloid ® Thiophosphoamide (o) Thioplex (t) Thiotepa TICE ® Toposar (t) Topotecan Toremifene Tositumomab Trastuzumab Tretinoin Trexall (t) Trisenox (t) TSPA (o) VCR (o) Velban (t) Velcade ® VePesid (t) Vesanoid (t) Viadur (t) Vidaza (t) Vinblastine Vinblastine Sulfate (o) Vincasar Pfs (t) Vincristine Vinorelbine Vinorelbine tartrate (o) VLB (o) VM-26 (o) VP-16 (t) Vumon (t) Xeloda ® Zanosar (t) Zevalin TM Zinecard (t) Zoladex ® Zoledronic acid Zometa ® See? There's a lot of them. Answered by Ammie Calligan 6 months ago.

antineoplastics, monoclonal antibodies, Answered by Ralph Lizarraga 6 months ago.

Please see the webpages for more details on Chemotherapy. Answered by Selina Musemeche 6 months ago.

How do I become familiar with this medication list?
Like a week before school my prof. emailed me this medication list to be familiar with and write up....Is there an easier way to look up all these meds and not have to write them out? She wants me to do a drug sheet for each...Medications ListTypeMedicationAnalgesic/ UrinaryPhenazopyridine... Asked by Juli Bakowski 6 months ago.

Like a week before school my prof. emailed me this medication list to be familiar with and write up....Is there an easier way to look up all these meds and not have to write them out? She wants me to do a drug sheet for each... Medications List TypeMedication Analgesic/ UrinaryPhenazopyridine (Pyridium) Ditropan Detrol AntibioticAmikain Amoxicillin Amoxicillin/ Clavulanic Acid Amhotericin B Ampicillin Ampicillin/ Sulbactam (Unasym) Azthromycin Bactracin Cefazolin Cefazolin 1/ Metronidazole Ceftazidime Cefuroxime Ciprofloxacin Clindamycin Clotrimazole Trouche Demeclocycline Dicloxacillin Doxycycline Erythromycin Fluconazole Gentamicin AntibioticIsoniazid (INH) Ketoconazole Levofloxacin Linezolid (Zyvox) Metronidazole (Flagyl) Miconazole Neomycin Sulfate (Bacitracin) Nystatin Oxacillin Penicillin G Benz/ Procaine Penicillin G Benzathine Penicillin G Potassium Penicillin G Procaine Penicillin V Potassium Piperacillin Piperacillin/ Tazobactam (Zosyn) Polymyxin B Sulfate (Neosporin) Pyrazinamide Rifampin Tetracycline Tobramycin Tygacil Unasym Vancomycin AnticoagulantEnoxaparin Heparin Warfarin Vitamin K Antiemetic-5- HT3- AntagonistCompazine, Zofran Class II Controlled SubstanceHaldol Codiene Fentanyl Hydromorphone Meperidine HCL (Demerol) Methadone HCL Methylphenidate HCL (Ritalin) Morphine Oxycodone Oxycodone 5 mg/APAP 325 mg Class III-V Controlled SubstanceAcetaminophen/ Codeine 120/12 Acetaminophen/ Codeine 300/30 Alprazolam Clonazepam Codeine/ Calcium Iodide Diazepam Diphenoxylate 2.5 mg/ Atrophine (Lomotil) Guifenesine/ Codeine 200/20 Hydrocodone 5mg/ APAP 500mg Lorazepam Midazolam Class III-V Controlled SubstancePhenobarbital Propoxyphene (Darvon) Temazepam (Restoril) Zolpidem CorticosteroidsBetamethasone Cortisone Acetate Dexamethasone Hydrocortisone Methylprednisolone Predinisolone Prednisone Flu Prophylaxis& Pneumonia vaccine IV Nutritional AgentsTPN/PPN LaxativesColace Senikot S Lactulose Citrate of Magnesia M.O.M. Lasix& Bumex Spironolactone (Aldactone) Quinapril (Accupril) Metoprolol XL (Toprol) Diltiazem CD (Tazar) Digixon (Lanoxin) Atenolol (Tenormin) Amiodarone (Cordorone)Coreg Nadolol (Corgard) Betapace (Altace) Respiratory MedsXopenex Albuterol Atrovent Beclomethasone Budisonide (Pulmicort) Mucomyst Olanzcypine (Zyprexa) Fluctretine (Prozac)& Zoloft, Buspar Alprazolan (Xanax)& Wellbutrin Lecothyroxine (Synthroid) Ferrous Sulfate Calcium Carbonate Aldentronate Updates were made by staff and I didn’t have time to check for doubles. Please add the following: Pancreas? Kayexalate Megace Phoslo Iron (Feosol) MVI (multivitamin) Actos Namenda Metformin Insulin all types Sinemet Narcan Romazicone Nulytely Librium Answered by Shirleen Pharris 6 months ago.

That's a hell of a list. Honestly the only way you're going to get them memorized is either to give them regularly (if you're a nurse) or to write them all down. Write down what they are for, dosages, side effects, etc. Literally doing it helps you get them down. You already have many of them separated by their effects which is good and is a starting point. Answered by Liza Semsem 6 months ago.

OMG this is a dream come true for me! I used to be a CPht and I miss it. I don't know if *you* have ever worked in a pharmacy but they keep a giant brown book that includes the information on every single drug known to man. It's the stuff you'd find in the folded pamphlet that accompanies drugs inside the bottles. I worked for Walgreens, but it's been a couple of years. I'm not sure if they still keep it around, call the Pharmacist on duty and ask about it. See if it's available anywhere else, like a medical library you might have access to? Answered by Viviana Rumschlag 6 months ago.

Yes, it can turn into a mental ilness. Don't listen to the other two people who responded. An overactive imagination about success and wealth and other things of that nature can lead to frustration and possibly into a serious mental condition. You need to focus on reasonable and real things, and It doesn't help you are on anti-depressants. Answered by Barabara Tzeremes 6 months ago.

Lump on Dachshund Ear?
My pure bred Doxie developed a hard, flat lump in her ear flap. It was about 1/4" About a month later, a bubble started to form close to the area, on the edge of her ear. It seems to be filled with fluid or blood, as it is squishy. It doesn't seem to cause her any pain, but I'm worried because it's constantly... Asked by Ocie Grabauskas 6 months ago.

My pure bred Doxie developed a hard, flat lump in her ear flap. It was about 1/4" About a month later, a bubble started to form close to the area, on the edge of her ear. It seems to be filled with fluid or blood, as it is squishy. It doesn't seem to cause her any pain, but I'm worried because it's constantly changing -- now the edge of her ear is curling under where the "bubble" is. What's wrong with my baby?! Answered by Salvatore Cheater 6 months ago.

It sounds like a hematoma.It needs to be drained by the vet.This will cause damage to the ear as you see now,with the curling.If it isn't taken care of it will cause a deformed ear.Here is some information: What is an aural hematoma? Aural hematoma, the underlying source of "cauliflower ear," is a collection of bloody fluid under the skin or between the cartilage layers of the pinna — the upright or floppy skin appendage above the ear canal. Aural hematomas are thought to be secondary to trauma. Vigorous head shaking in animals with external ear canal irritation causes the tiny vessels that perforate the internal cartilage to rupture and bleed. Although pressure building up under the skin will stop the bleeding, continued head shaking will cause the pocket to enlarge until it becomes a very noticeable and sometimes uncomfortable. Not all dogs and cats that have aural hematomas have ear infections; in fact, between 15% and 45% of affected animals may have no evidence of external ear canal disease. Because head shaking is thought to be the underlying traumatic event that leads to hemorrhage, ear and skin examinations should be performed by a veterinarian on all affected animals to rule out or diagnose predisposing conditions. Allergies to food or reaction to chemicals in the environment may be underlying causes in many dogs. Treatment of aural hematomas can either be medical or surgical. Surgery will rapidly reduce the size of the fluid pocket, but may result in some disfigurement and usually requires 2-3 weeks of bandaging or drain care. Medical management requires the use of steroids to reduce pain and inflammation and to control the underlying cause of the ear canal irritation. Steroids should never be given to dogs that are receiving medication such as Rimadyl or Deramaxx for arthritis or other painful conditions, since dogs on these drugs are more prone to gastrointestinal ulcers and upset. Your veterinarian will help you decide which treatment is best for your dog. Medical management Conservative treatment involves drainage and flushing of the hematoma through a small incision or with a large needle, and administration of corticosteroids by mouth or into the hematoma cavity. The cavity can be injected once daily with dexamethasone (a short acting steroid), or weekly with methylprednisolone acetate (a long acting steroid) until the hematoma resolves. Animals treated with daily intracavitary injections of dexamethasone usually heal within 3-6 days. Animals that receive intracavitary methylprednisolone acetate may require a second or third injection, but most resolve with a single treatment. Bandaging of the ear is not necessary except to seal the drain hole or to prevent vigourous shaking. Hematomas resolve in 90% of patients treated with local infusion or oral administration of corticosteroids, most likely because the irritation caused by the underlying problems (i.e. allergies) has been treated as well. Surgical treatment A variety of surgical treatments have been used for aural hemotomas. The hematoma can be drained and flushed through a long S-shaped incision on the inside surface of the pinna. The separated layers of tissues are then apposed with through-and-through sutures to keep the cavity collapsed and compressed. A gap is left at the incision to allow continued drainage of the hematoma, and the ear is bandaged down across the neck or up over the head to prevent self-trauma and to absorb additional fluid. This type of treatment allows the hematoma cavity to be cleaned out well; however, the ear may thicken and wrinkle as it heals, leading to permanent deformity. Alternatively, the hematoma cavity can be drained with a teat cannula, a small tube used to drain infected cow udders, or with a continuous suction drain made from a butterfly catheter. A suction device (a vacuum tube used for blood collection) is attached to the butterfly catheter to keep negative pressure on the drain. The ear is bandaged against the dog's head or neck, and the vacuum tube is changed as needed to maintain continuous suction and compression of the hematoma cavity. In most dogs, drains must be left in 2-3 weeks, since early removal will often lead to recurrence of the hematoma. Carbon dioxide lasers have also been used to make drainage holes and to stimulate the layers of the ears to heal together. As with the other surgical techniques bandaging is usually necessary to keep the ear compressed until it is healed. Answered by Stacey Crumpler 6 months ago.

Probably an aural haematoma. It needs to be fixed by the vet. Answered by Lisbeth Weinreich 6 months ago.

Off to the vet's immediately. The changes aren't good. Answered by Davis Schissel 6 months ago.

do you think they might be ticks? Answered by Yoshiko Toan 6 months ago.

Don't be alarmed.but you need to get your dog to the vet.It may be cancer. Answered by Carmella Rowray 6 months ago.

Any remedy for female alopecia besides propecia?
Asked by Karl Hennings 6 months ago.

Antiandrogen Treatments for AGA » Spironolactone - This is the most well known and at this time highly recommended oral Antiandrogen for women available. We know of more than a few women who have had good success in regrowing their hair with it. It is available by prescription through your dermatologist and is recommended in oral doses of 100-200 mg/day. Some other antiandrogens that may help are: » Flutamide - 250mg orally 3 times a day » Cimetidine - 300mg orally 5 times a day » Dexamethasone - 0.25 to 0.75mg per night » Cyproterone Acetate - 50 to 150mg a day (not available in US) » Desogestrel: Desogen, Ortho-Cept » Norgestimate: Ortho-Cyclen, Ortho Tri-Cyclen (yes it can potentially grow hair too!) » Norethindrone: Micronor, Nor-OD, Ovcon-35, Brevicon, Modicon, Ortho-Novum 7/7/7, Ortho-Novum 10-11, Tri-Norinyl, Norinyl and Orthol/35 » Ethynodiol diacetate: Demulen 1/35 » Levonorgestrel: TriphasilfTri-Levlen, Nordette » Norgestrel: Lo/Ovral, Ovrefte, Ovral » Norethindrone acetate: Loestrin 1/20, Loestrin 1.5/30 » Gonadotropin-releasing hormone agonists » Leuprolide (Lupron-Depot), 3.75 mg/month intramuscularly, plus 0.625 mg conjugated estrogens and cyclic medroxyprogesterone acetate 10 mg (from days 1-12 of each month) » Nafarelin (400 [Lg intranasally twice a day), plus Norinyl 1/35 tablets daily for 21 of 28 days, orally Answered by Xiomara Galiano 6 months ago.

Effects of steroids on body systems?
hey, i've got an assignment due and i need to know the affects of steroids on the respitory, and skeletal systems. thanks Asked by Bobette Kolar 6 months ago.

Steroid hormone From Wikipedia, the free encyclopedia Jump to: navigation, search Steroid hormones are steroids that act as hormones. Steroid hormones can be grouped into five groups by the receptors to which they bind: glucocorticoids, mineralocorticoids, androgens, estrogens, and progestagens. Vitamin D derivatives are a sixth closely-related hormone system with homologous receptors, though technically sterols rather than steroids. Contents [hide] 1 Synthesis 1.1 Synthetic steroids and sterols 2 Effects 3 References 4 Further Reading 5 External links [edit] Synthesis Further information: Steroidogenesis Steroids made from cholesterolThe natural steroid hormones are generally synthesized from cholesterol in the gonads and adrenal glands. These forms of hormones are lipids. They can pass through the cell membrane as they are fat-soluble, and then quite easily combine with a protein receptor which may be nuclear of cytosolic depending on the steroid hormone, to bring about changes within the cell. Steroid hormones are generally carried in the blood bound to specific carrier proteins such as sex hormone-binding globulin or corticosteroid-binding globulin. Further conversions and catabolism occurs in the liver, in other "peripheral" tissues, and in the target tissues. All of the hormones in the endocrine system are steroid based, and all of the hormones in the exocrine system are non-steroid. Steroidogenesis with enzymes and intermediates [edit] Synthetic steroids and sterols A variety of synthetic steroids and sterols have also been contrived. Most are steroids, but some non-steroidal molecules can interact with the steroid receptors because of a similarity of shape. Some synthetic steroids are weaker, and some much stronger, than the natural steroids whose receptors they activate. Some examples of synthetic steroid hormones: Glucocorticoids: prednisone, dexamethasone, triamcinolone Mineralocorticoid: fludrocortisone Vitamin D: dihydrotachysterol Androgens: oxandrolone, nandrolone (also known as anabolic steroids) Estrogens: diethylstilbestrol (DES) Progestins: norethindrone, medroxyprogesterone acetate [edit] Effects Steroids exert a wide variety of effects mediated by slow genomic as well as by rapid nongenomic mechanisms. They bind to nuclear receptor in the cell nucleus for genomic actions. Membrane-associated steroid receptors activate intracellular signaling cascades involved in nongenomic actions. Because steroids and sterols are lipid-soluble, they can diffuse fairly freely from the blood through the cell membrane and into the cytoplasm of target cells. In the cytoplasm, the steroid may or may not undergo an enzyme-mediated alteration such as reduction, hydroxylation, or aromatization. In the cytoplasm, the steroid binds to the specific receptor, a large metalloprotein. Upon steroid binding, many kinds of steroid receptor dimerize: Two receptor subunits join together to form one functional DNA-binding unit that can enter the cell nucleus. In some of the hormone systems known, the receptor is associated with a heat shock protein, which is released on the binding of the ligand, the hormone. Once in the nucleus, the steroid-receptor ligand complex binds to specific DNA sequences and induces transcription of its target genes. [edit] References 1. Brook CG. Mechanism of puberty. Horm Res. 1999;51 Suppl 3:52-4. Review.PMID: 10592444 2. Holmes SJ, Shalet SM. Role of growth hormone and sex steroids in achieving and maintaining normal bone mass. Horm Res. 1996;45(1-2):86-93. Review. PMID: 8742125 3. Ottolenghi C, Uda M, Crisponi L, Omari S, Cao A, Forabosco A, Schlessinger D. Determination and stability of sex. Bioessays. 2007 Jan;29(1):15-25. Review. PMID: 17187356 4. Couse JF, Korach KS. Exploring the role of sex steroids through studies of receptor deficient mice. J Mol Med. 1998 Jun;76(7):497-511. Review. PMID: 9660168 5. McEwen BS. Steroid hormones: effect on brain development and function. Horm Res. 1992;37 Suppl 3:1-10. Review. PMID: 1330863 [edit] Further Reading Simons SS Jr. What goes on behind closed doors: physiological versus pharmacological steroid hormone actions. Bioessays. 2008 Aug;30(8):744-56. PMID: 18623071 [edit] External links Steroid Hormone Action (a Flash Animation) Steroidogenic enzymes: Review on structure, function, and role in regulation of steroid hormone biosynthesis [hide]v • d • eEndocrine system: hormones (Peptide hormones · Steroid hormones) Endocrine glands Hypothalamic- pituitary Hypothalamus GnRH · TRH · Dopamine · CRH · GHRH/Somatostatin Posterior pituitary Vasopressin · Oxytocin Anterior pituitary α (FSH FSHB, LH LHB, TSH TSHB, CGA) · Prolactin · POMC (ACTH, MSH, Endorphins, Lipotropin) · GH Adrenal axis Adrenal cortex: aldosterone · cortisol · DHEA Adrenal medulla: epinephrine · norepinephrine Thyroid axis Thyroid: thyroid hormone (T3 and T4) · c Answered by Felicitas Stillman 6 months ago.

It depends on the type of steroids you're referring to. There's anabolic and corticosteroids. The word steroid refers to hormones. Each type affects different parts of the body, and the amounts that is taken dictates the severity of symptoms and/or damage. Answered by Florentina Payano 6 months ago.

Prolonged use leads to liver problems, heart problems, artery clogging, fertility issues, baldness, acne, and numerous other things. People also tend to get edgy and paranoid, which can cause them to make erratic decisions. Answered by Mickey Mancusi 6 months ago.

Mostly shutting down natural production of testosterone everything else is exagerrated but who wants to have that problem? Answered by Clair Cantrelle 6 months ago.

there are positive and negative effect of anabolic steroids Answered by Cornelius Grober 6 months ago.

edginess paraniod feelings impatincs Answered by Shandra Gossom 6 months ago.

Can adrenal insufficiency cause high blood pressure also?
I have heard of charged water, but given in a different way by readings of Edgar Cayce. Thanks so much for your information. Asked by Eleonor Gallogly 6 months ago.

Primary adrenal insufficiency, also known as Addison's disease, occurs when the adrenal glands cannot produce an adequate amount of hormones despite a normal or increased ACTH (adrenocorticotropin hormone) level. Most patients with Addison's disease experience fatigue, generalized weakness, loss of appetite, weight loss and low blood pressure with lightheadedness after standing or sitting up. Treatment of adrenal insufficiency involves the administration of adrenal hormones to mimic the normal output by the adrenal glands. Underactivity of the adrenal glands is called hypoadrenalism. Many of the symptoms of hypoadrenalism are due to a deficiency of the steroid hormone cortisol, which is a potentially fatal deficiency if left uncorrected. Other corticosteroids may be used to treat hypoadrenalism, including cortisone acetate, prednisolone (eg Deltacortril) and dexamethasone. However, it is difficult to judge the correct dose of prednisolone and dexamethasone. This may lead to the complications of long-term steroid treatment including avascular hip necrosis, osteoporosis, worsening of diabetes mellitus and HYPERTENSION(high blood pressure). Cortisone acetate must be converted by the body into an active steroid, and the efficiency of conversion may vary between patients. You should talk to your doctor for more details. Take care as always! Answered by Antonia Dastrup 6 months ago.

Adrenal Glands (Point no. 28) : These glands control and regulate the fire element of the body and so control the spleen, liver and gall bladder and assist in the creation of biles and digestive juices. Qualities like keenness of perception, untiring activity, the drive to action, inner energy and courage are due to proper functioning of these glands. They also intensify the flow of blood, help proper oxygenation and develop organising power-inspire to leadership. They play an important part in the character building of a child. In the case of disorder of these glands, persons abuse their natural vigour to satisfy their lust or antisocial activities. They suffer from a sense of vain glory and are conceited-become extremely restless-impatient and short-tempered. They cannot have control on diet and suffer from stomach problems and blood pressure. Case Study: "A Prince had lost interest in life from the age of 16. He stopped studies in the final year of University and had no interest even in sex. So, he did not marry. At the age of 31, after he unsuccessfully tried treatment under various therapies, he consulted an acupressurist. On examination, his thyroid and adrenal glands were found to be damaged. The acupressurist told that the cause of all his troubles was some type of deep fear, a severe shock which had damaged his adrenal gland. The King admitted that the Prince had at the age of 16 joined him on a hunt and had fallen down from the horse and was miraculously saved from a tiger. Since then he had halucinations and lost interest in life. The prince was given Acupressure treatment and gold-silver-copper charged water to drink. Within 30 days he became normal and started taking interest in his hobby of painting and also in his usual chores." "A young professor came to our Free Centre on one Wednesday morning and informed me that he was so badly depressed that he desired to commit suicide. I agreed that he should commit suicide on the next Wednesday at 3.00 P.M. But meanwhile, he should take treatment on all endocrine glands and drink charged water during the week and report me on the next Wednesday morning. Thereon that day he came with a smiling face only to inform me that he wanted to live long and enjoy life." His desire to commit suicide had disappeared, Similarly, thousands of such cases can be quoted. with best compliments from Answered by Rubye Crickard 6 months ago.

Please see the web pages for more details on Adrenal insufficiency. Highly technical. Hence no comments. Answered by Gearldine Pane 6 months ago.

Yes it can. Answered by Richie Zack 6 months ago.

Steroid hormones?
Steroid hormones play a major part in controlling the growth processes, differentiating male from female bodies during development, modulating the immune system, and etc. How do steroid hormones interact with the cell's molecular machinery in order to produce their effects?Is it that they bind to receptor... Asked by Rochell Maontesano 6 months ago.

Steroid hormones play a major part in controlling the growth processes, differentiating male from female bodies during development, modulating the immune system, and etc. How do steroid hormones interact with the cell's molecular machinery in order to produce their effects? Is it that they bind to receptor molecules in target cells? Answered by Shena Gracey 6 months ago.

Most steroids act by regulating gene transcription from DNA. They do have specific receptors in target cells which help in the intake of the steroid. They are then processed to some other form that enters the nucleus and directly binds to specific DNA sequences, enabling or disabling transcription of some genes. For example, testosterone makes muscle cells manufacture more muscle proteins, enhances hair growth in follicles on face, etc... Answered by Ji China 6 months ago.

Peptide hormones are large proteins. They don't enter the cell. They interact with cell surface receptors, and those change configuration on the inside part when they are bound to the hormone, and that change causes changes to the cell's function. Answered by Gertie Landquist 6 months ago.

i thnk so they have the same action but am not quite sure Answered by Maris Fewless 6 months ago.

Why does people need medical steroids?
Why DO people. Ha just noticed that Asked by Marilou Lawbaugh 6 months ago.

Steroids are a group of chemicals which are normally produced in our body and serving many functions. Even plants produce steroids.. I will give a few examples. 1. Cortico trophins produced by the pituitary gland. They regulate a variety of functions in the body including regulation of sexual development. 2. Sex hormones . Both testosterone and oestrogen are steroids and are produced in the testicles and ovaries respectively.There are more examples. Most of these steroids produced in the body have been synthesised and there are synthetic analogues. In diseases that are due to deficiency of the above hormones these synthetic steroids can be administered. Such synthetic steroids are given as treatment for male and female sterility, and a variety of other illnesses. There are some steroids called the anabolic steroids produced by the body and they help in the growth of the body. Steroid derivatives like Stanazolol used wrongly for body building is such a synthetic analogue. Then there is a group of steroids eg. Cortisone acetate produced by the body and they mainly perform an anti inflammatory action. They help the body to combat inflammation Commonly used drugs like prednisolone, and dexamethasone are examples of synthetic derivatives and , as you know they are widely used for a variety of illnesses eg. Asthma. I have given an overall view. Please note that steroids are indiscriminately used by some doctors and patients and this is harmful to health. What you want is is a list of some medical reasons for use of steroids. They are. .Bronchial Asthma, Male and female Subfertility, Failure of growth, Contraception, Inflammatory lesions of joints,Rheumatoid Arthritis, Resuscitation of patients etc. after injury. And the list can go on. Answered by Marcelina Kosier 6 months ago.

Some steroids act as an immunosuppressant. I use steriods to control my graft v host disease that I have as a result of my stem cell transplant (medically correct term for a bone marrow transplant). It can also act as an anti-inflamatory. So it can help things like sinusititus, or allergic reactions along with benedryal. They are used all the time now in cancer patients to combat weight loss. THere are a lot of medical uses for steroids. Answered by Alda Dill 6 months ago.

1-To treat aftermath of testicular cancer to make sure man has enough testosterone to preserve secondary male traits. 2-Boys who have pituitary problems are given steroids at the time of puberty to create growth spurt; & to develop secondary male traits. 3-After cancer or surgery to stop muscle wasting. 4-Not legal in US, but to masculinize transgender women. Answered by Latarsha Sadhra 6 months ago.

Sometimes people need to use them for a bad rash, like from scabies or a bad poison ivy rash. It will basically "make the itching stop from the inside" lol Answered by Janean Tinnes 6 months ago.


ApplId/ProductId Drug name Active ingredient Form Strenght

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
016675/001 DECADRON-LA DEXAMETHASONE ACETATE INJECTABLE/INJECTION EQ 8MG BASE per ML **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**

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