DESYREL Ressources

Application Information

This drug has been submitted to the FDA under the reference 018207/001.

Names and composition

"DESYREL" is the commercial name of a drug composed of TRAZODONE HYDROCHLORIDE.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
018207/001 DESYREL TRAZODONE HYDROCHLORIDE TABLET/ORAL 50MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
018207/002 DESYREL TRAZODONE HYDROCHLORIDE TABLET/ORAL 100MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
018207/003 DESYREL TRAZODONE HYDROCHLORIDE TABLET/ORAL 150MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
018207/004 DESYREL TRAZODONE HYDROCHLORIDE TABLET/ORAL 300MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
018207/001 DESYREL TRAZODONE HYDROCHLORIDE TABLET/ORAL 50MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
018207/002 DESYREL TRAZODONE HYDROCHLORIDE TABLET/ORAL 100MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
018207/003 DESYREL TRAZODONE HYDROCHLORIDE TABLET/ORAL 150MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
018207/004 DESYREL TRAZODONE HYDROCHLORIDE TABLET/ORAL 300MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
022411/001 OLEPTRO TRAZODONE HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 150MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
022411/002 OLEPTRO TRAZODONE HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 300MG **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
070491/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 50MG
070942/001 TRIALODINE TRAZODONE HYDROCHLORIDE TABLET/ORAL 50MG
070492/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 100MG
070857/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 50MG
070858/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 100MG
070921/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 100MG
071112/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 50MG
071113/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 100MG
071139/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 50MG
071140/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 100MG
071196/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 100MG
071196/002 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 150MG
071196/003 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 300MG
071258/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 50MG
071405/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 50MG
071406/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 100MG
071514/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 100MG
071523/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 50MG
071524/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 100MG
071525/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 150MG
071636/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 50MG
072192/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 50MG
072193/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 100MG
072483/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 100MG
072484/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 50MG
073137/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 100MG
073137/002 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 50MG
073137/003 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 150MG
074357/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 150MG
090514/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 50MG
090514/002 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 100MG
090514/003 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 150MG
090514/004 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 300MG
202180/001 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 50MG
202180/002 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 100MG
202180/003 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 150MG
202180/004 TRAZODONE HYDROCHLORIDE TRAZODONE HYDROCHLORIDE TABLET/ORAL 300MG

Ask a question

A licensed doctor will try to answer your question as quickly as possible.

Answered questions

Effexor and desyrel together?
I am on 75mg effexor and asked my dr. for desyrel 100mg because I have a terrible time falling asleep. Since it is also an antidepressant , I told him I don't want to be on effexor anymore. He said desyrel wouldn't replace effexor. Any opinions on this? I feel like I should only be on one antidepressant. Asked by Delicia Miyares 2 months ago.

Desyrel doesn't replace Effexor. They work differently. Desyrel affects serotonin and Effexor affects serotonin, norepinephrine and dopamine. Because of it's side benefit of helping with sleep, Desyrel can be added, such as adding Desyrel with Prozac. It's not a problem. Answered by Fern Maier 2 months ago.

wouldn't that make you drowsy and sleepy? anyways i don't think its that bad Answered by Brook Wicke 2 months ago.


Has anyone here tried Desyrel?
I have done research on trazodone, and I am aware that different people get different side effects. I'm just trying to figure out roughly how common hair loss is in particular. With one answer from someone who hasn't necessarily tried it, I'm obviously not going to find out. Asked by Carmelina Alicandro 2 months ago.

You can find this information on webmd.com or drugs.com. Desyrel is a brand name and I do not believe it's even manufactured anymore, so you'd want to check under the generic name "trazodone". It would also be wise to consult a very under-used resource in the medical world, your local pharmacist, who can tell you everything you need/want to know and more. They are experts on medications and would be happy to help. Medications react differently in everyone, so if you poll the general population instead of seeking medical advice you are likely to get as many opinions/stories as answerers. Answered by Alica Beseau 2 months ago.


Trazadone (Desyrel) and booze. Answer asap. please.?
I know anti-depressants and booze don't go well together, but in moderation doctors normally say it's ok, depending on the person, circumstance, etc. I drank a bit tonight, and I normally take my trazadone at night, every night, but i'm feeling a bit weird, more aware of my pulse and heart, and whatnot.... Asked by Mickie Seifert 2 months ago.

I know anti-depressants and booze don't go well together, but in moderation doctors normally say it's ok, depending on the person, circumstance, etc. I drank a bit tonight, and I normally take my trazadone at night, every night, but i'm feeling a bit weird, more aware of my pulse and heart, and whatnot. my anxiety levels are at the top. i guess you could say im somewhat scared to take my traz tonight because im worried what will happen. the alcholol is morre than half out of my system, i ate, drank a lot of water and am now drinking tea. any advice? i'm just concerned. nervous. and uneasy. i havent drank for a long while and i regret it tonight. im done with booze. but should i take my meds tonight? :( i know if i dont ill feel off tomorrow. someone please help me out here Answered by Kristle Kiedrowski 2 months ago.

The reason you are warned to avoid taking your Desyrel with alcohol is because it has a similar chemical reaction and process inside of your brain. The concern is that you can get alcohol exaggerated symptoms, either depression or lack of motor skills. If you feel to drunk just drink tea and/or water and wait til you are feeling better then take your trazadone, you will be fine I'm sure. It will not poison you in normal circumstances (like those that you described as your evening events). Answered by Lorette Sorce 2 months ago.

You will be fine. Answered by Nita Hausladen 2 months ago.


Does anyone know if there is a generic available for the drug Trazodone/Desyrel?
Asked by Karrie Perlstein 2 months ago.

Trazodone IS the generic for Desyrel, Molipaxin, Trittico, Thombran, Trialodine. Answered by Loise Edson 2 months ago.

Trazodone is the generic. Desyrel is the brand name. Hope this helps. Answered by Mechelle Mcanally 2 months ago.


Trazodone (Desyrel) As A Sleep Aid?
My doctor gave me trazodone, which is generic for Desyrel, as a sleep aid, and tonight is the first time i need to use it. Has anyone ever used it for this? How long does it take to work? What was your dosage and how many hours did it make you sleep? Was it hard to wake up? Were you tired the next day? Thank you so... Asked by Jesse Cirella 2 months ago.

My doctor gave me trazodone, which is generic for Desyrel, as a sleep aid, and tonight is the first time i need to use it. Has anyone ever used it for this? How long does it take to work? What was your dosage and how many hours did it make you sleep? Was it hard to wake up? Were you tired the next day? Thank you so much... Answered by Shawanda Beneke 2 months ago.

This has become more excepted for a sleep aid. My patients take up to 300 mg a day! Usual dose I believe ie 50-150 mg. I will work to make you sleepy. Don't expect too much.....Just let it work. If you expect oo much you'll be wide awake all night. Good luck! Sleep tight! Answered by Wilber Mclamb 2 months ago.

Haven't tried it yet, but was wondering why I would be prescribed an antidepressant for a sleep aid. Anyone that can answer this question will receive a thank you and a congratulations on your education. Answered by Brandon Conradt 2 months ago.

I was on 50 mg. Nothing has ever worked better for me. It was given to me as an addition to my antidepressants during the day, because they were making it harder to sleep than usual. As long as I took my antidepressants in the morning, I had no trouble waking up. In fact, it was easier, because I wasn't so tired after not sleeping enough. Really an awesome medication, and I highly recommend it. Answered by Dania Tippen 2 months ago.

yes used to be on it , worked great, but had bad dreams, was'nt tired in the morning, took about 30-45 mins. to work, made me feel drunk b4 falling asleep Answered by Kathe Mccrimmon 2 months ago.


Can you smoke the pill, Trazodone (Desyrel)?
Taking the pill orally gives you a mild "stoned" feeling, but also makes you extremely sleepy. I'm on probation right now, and can't smoke weed - so If it's possible to smoke Trazodone, and still get the "stoned" feeling, that would be great! Asked by Kemberly Rykiel 2 months ago.

I'm sorry but what??? Why would you want to do that? Maybe you need to ask yourself why you're on probation and then stop doing the things that got you there...like smoking things. Answered by Brain Sippel 2 months ago.

Natural Quit Smoking Magic Answered by Ezra Ganther 2 months ago.

dont listen to these people. they only say it, because of how people have done things wrong and died over. shooting a pill.... most of the time u dont melt anything down....there is no need. there is only a few kinds that u would actually melt.. melting is usually for heroin. crunch pill, mix with water...add a cotton ball so none of the filers in the pill are sucked into the needle, get air bubble out....wrap something around arm to find a vein...inject into vein, pul back the plunger, make sure u see blood, and then push.... and yes u can smoke trazadone. Answered by Kassandra Unruh 2 months ago.

ABSOLUTELY NOT, and don't try to melt it and shoot up,either.More and more often, the cause of death in found in drug users is from the binding agents in tablets being injected or inhaled, then settling in the lungs, where it becomes extremely toxic. Answered by Elin Neldon 2 months ago.

NO, there is no way to smoke trazodone. Trazodone is used for depression/sleeping. Answered by Carson Kuiz 2 months ago.

Can You Shoot Up Trazodone Answered by Adina Kirchausen 2 months ago.

nope, but snorting it is crazy! Answered by Fritz Martens 2 months ago.


Trozodone Desyrel overdose?
After getting into rehab and off her addiction, my sister has developed (or re-introduced) depression and she's taking a variety of antidepressant medications (concurrently zolofts, celexa, belbutrin etc.) for the past year. The last one now (Prozac 40-60 mg) had Lamictral added (an anti-convulsant/bi-polar med),... Asked by Crystle Budrow 2 months ago.

After getting into rehab and off her addiction, my sister has developed (or re-introduced) depression and she's taking a variety of antidepressant medications (concurrently zolofts, celexa, belbutrin etc.) for the past year. The last one now (Prozac 40-60 mg) had Lamictral added (an anti-convulsant/bi-polar med), but a diagnosis of bi-polar has not been confirmed . She told me that on Saturday she took about 9 Desyrel pills (thinking that they were 25mg pills when they were 50mg pills = 450mg). She was previously complaining about having very bad memory, confusion etc. I called her on Sunday afternoon, and she was miserable, I checked on her and she was all bruised and had a small hematoma on her back head. I asked her what had happened, and she said that she went to the bathroom last night and found herself on the floor twice (in the bathroom and later in the sleeping room) with has no recollection of what had happened (not feeling dizzy, or nauseated, not remembering the fall, just waking up confused, unknowing how long it had been etc. We helped her out a bit, and let her sleep (we didn't know about the meds at this time). the next few days she was very dizzy, unbalanced, sleepy etc.. Slowly these symptoms subsided by Wednesday, but there is still a confusion, short term memory problem. What is happening to her? Are these the effects of medication interactions/overdose/ or lesions from the previous substance abuse (alcohol, dmx, LDS, marijuana etc. We are concerned that this could be a permanent problem like Wernicke-Korsakoff syndrome (she's been off and clean for 4-5 months after 25 yrs. of abuse). Please no stupid comments, you could be affected with this terrible disease or have someone you love in your family having it. It's no fun to watch this. Answered by Anthony Elliot 2 months ago.

Sounds like the effects of overdose plus drug interaction to me. I don't think it's Wernicke-Korsakoff, but you might suggest to get a brain scan to rule that out (it may show distinct symptoms, degeneration of the hypothamus etc.) Answered by Iva Poitevin 2 months ago.

Effexor will supply you muscle spasms. Seroquel will placed you to sleep. The others I don't have any inspiration. Heres the item and I would be improper. I attempted to kill myself a couple of years in the past. One factor I have discovered over time is that if you're asking what system works and pronouncing you desire to do it then you're requesting support. Whatever you do please pass speak to anyone that may exhibit you the methods out of this considering. Killing your self is not going to clear up the sensation you've. It took me five attempts earlier than i understood what they have been telling me. Please get a few support. Answered by Alana Selvy 2 months ago.


Trazodone (Desyrel)? I'm not depressed.?
I was taking over the counter sleeping pills to make me fall asleep (Melatonin & Unisom) since im having trouble falling asleep right now, due to stress I guess..I talked to my DR and he said over the counter pills don't work so he prescibed Trazodone. I did some research and this is an antidepressant drug (Im... Asked by Ngoc Tubb 2 months ago.

I was taking over the counter sleeping pills to make me fall asleep (Melatonin & Unisom) since im having trouble falling asleep right now, due to stress I guess..I talked to my DR and he said over the counter pills don't work so he prescibed Trazodone. I did some research and this is an antidepressant drug (Im not depressed), I've only taken this pill twice and im extremely tired all day and feel down, a lil depressed, not in the mood to talk to anyone or I will get irritated when someone tries to joke around with me...what do you think I should do? Answered by Ashlie Mins 2 months ago.

Trazodone was developed as an antidepressant but it is not used for that purpose anymore because there are many other drugs that work better without the sedating side effects. It is used as a sleep aid, which is why you got it. Some people have a reluctance to use psychiatric drugs, even if they are not being used for psychiatric purposes, for no other reason than the fact that they themselves attach a stigma to it. They are fools. If you want to sleep, take the pills. If not... It's your call. Answered by Shay Tartaglione 2 months ago.

It is uncommon for both amitriptyline 50 mg and trazodone (what dose??) to be prescribed at the same time. Is the amitriptyline for headaches, pain, depression, anxiety, insomnia? Often amitriptyline (although using trazodone is more common) is prescribed for insomnia so (setting drug interactions aside) it sounds rather redundant. There are drug interactions between medications but it is typically safe and you are taking a LOW dose of amitriptyline and I assume your doctor prescribed 50-150 mg of trazodone, which is not a very large dose. I would ask the neurologist about using both- if both the psychiatrist and neurologist are OK with you taking both medications then it should be fine. Taking both could certainly be more sedating but for the most part, unless you have certain other significant health problems, it should be fine. You could also ask your doctor to prescribe you a FDA approved hypnotic for insomnia rather than using trazodone. Lastly there is a lot of information about these medications you can find but often it is too generlized or simply wrong. When it comes to psychiatric medications often unconventional medication uses are common. So what may look odd may not be. And although a combination like this is rare it is not unheard of. Answered by Li Angeloff 2 months ago.

Trazodone is also used for sleep disorders such as insomnia since a good majority of those studied using the drug have had their sleeping disorders addressed as well as others had the 'sleepy' or 'Drowsy' side effect. I personally do not like the idea of reverting to drugs/ medications to answer problems unless I cannot find a more natural/ safe way to resolve the issue. The Problem with medications: -Most medications are designed/ assigned specific functions based on a laboratory and controlled studies. Unfortunately each person has a particularly unique PH (Chemical Balance) with a majority of individuals having a similar/ within close range of PH balances that drugs/ foreign chemicals introduced to their body has a very similar effect.) But for some it may have a reverse or even fatal effect because of their own PH balance. -It is most often not the drug that causes the 'cure' but the chemicals produced by the body in it's attempt to isolate, neutralize, and or expell these foreign toxins from the body which gives the side effect of pain relief/ happiness etc... - Since these are foreign toxins (for all intents and purpose) put a load on the Kidneys & Liver which is are the organs that filters' such things from the body's liquids and most often some of these gets embeded in the walls of said organs thus caused organ tissue damage & or cancer later on. General Cause for Insomnia/ Sleeplessness: -Too much thoughts/ worries going on in the brain due to events at home, work, school, and or relationships... -Too much excitement either from abstract thoughts/ ideas, pending schedule/ events. -A major change in one living environment/ regime such as new location, less body workout than before or more, change in diet (sometimes unbalanced) and comsuming more sugar/ carbohydrates, or more drinks containing checmicals which enduces alertness. I am bi-polar with manic disorder and have suffered from insomnia, but I have stopped taking all my medications for 3 years now mainly because I have become more aware of my diet and exercise as well as finding venues to channel my life through. I have started hiking more often & ride the bicycle, I have started writing and also started doing music I spend time with others that can benefit from my presence such as a weekly visit to the elderlies at the rest home and the youth groups to help them in thier understanding of life & personal beliefs... When your body is also undergoing a form of muscular decay/ atrophy due to lessened levels of activity cetrain parts of your body will have a 'numbing/ pressuring' sensation that is difficult to ignore -tis will also make you not able to get to sleep and the best thing to do is to try to 'sweat it out' by doing a rigorous excercise and check your diet to see what nutrients/ vitamins/ minerals your lacking in intake and take a supplemental vitamin pill like once a day centrum etc... until you get your diet back into proper control. Good luck and I didn't mean for this to be s wordy. Answered by Giselle Arenivas 2 months ago.

Instead of taking such medicines, which spoils the normal balance of our mind, I would suggest some other easy, simple and natural methods to keep our mind pure and fresh. Mind is starving for truth, peace, happiness, knowledge, etc. We can feed these. Secondly the main substance of our mind is made up of matter also. If we take our solid and liquid food which are pure, fresh, nourishing, delicious, energetic like green vegetables, fruits, fruit juices, honey, milk, yogurt, butter, lemon juices, pulses, cereals, etc. it will keep our mind fresh. Avoid all other stuff which may spoil our mental balance. Answered by Nohemi Gurrola 2 months ago.

Ahh, I know exactly what you should do. Ask your doctor if you can go down on the dose! PLAVIX IS A BLOOD THINNER, I THINK! IT CAN PUT YOU AT RISK FOR BLEEDING! Answered by Elayne Stoppkotte 2 months ago.


Is trazodone(desyrel) worth taking for anxiety and sleep problems?
I suffer from extreme anxiety and depression. I used to stay worried, nauseated and tired. I am taking zoloft which has eliminated the nausea which is great but I still get sudden anxiety attacks . You know the gut wrenching ,tightness, and fever type. I also cannot sleep at all .I cannot get my head to stop or... Asked by Ladonna Kaps 2 months ago.

I suffer from extreme anxiety and depression. I used to stay worried, nauseated and tired. I am taking zoloft which has eliminated the nausea which is great but I still get sudden anxiety attacks . You know the gut wrenching ,tightness, and fever type. I also cannot sleep at all .I cannot get my head to stop or slow down . It is constantly thinking. Any help would be appreciated . Any new meds maybe I havent tried . Answered by Ouida Garzon 2 months ago.

ABSOLUTELY i take it every night not only does it help you sleep but it helps to keep your anxiety level to a minimum you are headed in the right direction with trazodone i have felt so much better since starting treatment with that take a pill out in 15 min and wake not having that anxious feeling go for it good luck to you Answered by Tommye Gillie 2 months ago.

Getting good sleep is important for anxiety and depression. Trazedone before bedtime can help you sleep. It's not habit forming. The other thing to try is exercise. It can be as simple as a long walk each day. That will relax you. Try taking a walk with your favorite music playing on your iPod. Make sure you have someone to talk to. Your problem is not unusual. Answered by Tyson Lint 2 months ago.

I take trazodone and have for 15 years but the milligrams are high--250 to 300 each night . It really makes you sleep good and works very well for me for depression and anxiety. Smaller doses might work for you but your doctor would have to help you with that. Wouldn't it be horrible if our brain didn't think , yet I know at times we wish it would just shut up and give us some rest . the trazodone will help with that also. good luck!! Answered by Elias Melanson 2 months ago.


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