DAPTOMYCIN Ressources

Application Information

This drug has been submitted to the FDA under the reference 091039/001.

Names and composition

"DAPTOMYCIN" is the commercial name of a drug composed of DAPTOMYCIN.
It belongs to the class Other antibiotics and is used in Bacterial infections (Infections and Infestations)

Answered questions

Daptomycin for home use.?
My father-in-Law needs extended use (12 weeks or more) of IV Daptomycin, 500 mg/day. He is on Medicare and is in a nursing facility to receive the medication. He would like to go home and receive the medication at home. This increases the expense because he would have to pay for the medication out of... Asked by Cary Desiga 4 months ago.

My father-in-Law needs extended use (12 weeks or more) of IV Daptomycin, 500 mg/day. He is on Medicare and is in a nursing facility to receive the medication. He would like to go home and receive the medication at home. This increases the expense because he would have to pay for the medication out of pocket. Can it be done at home and what would it cost for each moth of treatment? Answered by Jacque Morkert 4 months ago.

I'm not aware of an oral form of daptomycin (Cubicin) so he'll have to have IV access maintained or a central line placed so the peripheral IV site doesn't need to changed every 72 hours. IV antibiotic infusion can be done at home if administered by an IV certified home health nurse who is also an RN. Be advised that I speak for one state only. I don't know where your father-in-law resides or what the state nursing practice act there is. It's entirely possible that in his state LPNs may administer IV antibiotics and this in their scope of practice. If so, this is less costly than having an RN handle it. There are home infusion companies that can arrange everything. Speak to his social worker/case manager at the nursing home and/or speak to a Medicare representative and find out exactly what his options are. These are your two best sources of information and help. For now I can tell you that daptomycin may be administered at home and since his dose is 500mg, the Mini-bag system made by Baxter can be used. The availability of a specific infusion such as Cubicin, depends on the Medicare formulary in his state and his plan benefits under Part D. Under Part D, he may need to pay out-of-pocket for supplies and home administration but it's more important to find out if the med is covered. But as I said, speak to one or both the sources I mentioned. This isn't the right place for your question. I'm just not a case manager or insurance rep, and that's who you need to be talking to. Or he could make things easier and remain in the nursing home until the infusion protocol is completed. Speak to both his case manager AND Medicare today! Answered by Rolanda Albarez 4 months ago.


Concerning Daptomycin?
Why is it only used for complicated gram positive infections but not simple ones? Asked by Ginette Spinney 4 months ago.

because this medications is expensive. Simple gram positive can be treated with simple less expensive medications such as members of the PCN family with gram positive coverage or Clindamycin. Answered by Craig Labate 4 months ago.


Is there any danger on the use of the combination of the medicines methadone daptomycin?
My step dad is currently taking these two medicines and I was wondering if there is a danger or something to using them both at once? Asked by Glenn Mencke 4 months ago.

There are no known interactions between Methadone and Daptomycin. Good Health! Answered by Otelia Mcanaw 4 months ago.


I NEED AN ANSWER ON A MEDICATION & THE SIDEAFFECTS?
DAPTOMYCIN 465MG IN 100ML IV Asked by Martine Cossio 4 months ago.

Call a pharmacist they know all about medications. Don't ask someone on here ! Answered by Nettie Veeneman 4 months ago.

Ummm I think the side effect are blood creatine phosphokinase increased, rhabdomyolysis, skin exfoliation, rash erythematous, fall, rash, pruritus, erythema, myositis, xerosis, skin ulcer. If you don't know what some are just look them up. :] Answered by Marcelene Wlodarek 4 months ago.

pain, swelling, or redness at the injection site; nausea; vomiting; mild diarrhea; constipation; headache; dizziness; or trouble sleeping Answered by Gina Helena 4 months ago.


I was given Zoysn for four days and then daptomycin IV for three weeks?
The doctor switched me to Zyvox last Saturday. I hope you are right about my WBC - first day in the hospital (6/27) it was 11.5 now it is 5.6 and neut % dropped from 51 to 28% Asked by Kenia Leasor 4 months ago.

Zyvox (Linezolid) is a synthetic antibiotic. I'd assume you are on 600mg twice daily (orally or intravenously), though your dosage could be lower than that, you'd have to ask your doctor. As far as I'm aware, 600mg twice daily is the appropriate dose for an adult, but sometimes it is given only once daily. It works well either way. It is possible to develop resistance to Linezolid, but I hope you don't. In regards to your WBC, I don't know what your CBC was, obviously, but when a person has a bacterial infection, the WBC can increase dramatically, but yours has dropped (Leukopenia). A normal WBC is between 4,500 and 10,000 cells per microliter. Below 4,500 doesn't suggest a serious illness, but below 2,500 increases the risk of seriousinfection as the white blood cells make up a large amount of the body's immune system. Get better soon and take care of yourself dude. =) Answered by Cedrick Garrick 4 months ago.


I have been on IV Daptomycin for MRSA for three wks-my WBC dropped from 11.5 to 5.6 - do I worry?
also, my neut % is down from 51% to 28% Asked by Nelda Trimmell 4 months ago.

it must have been very difficult for you. antibiotics as well as infection can cause these blood results. follow up with your dr, i hope you recover soon. Answered by Veda Stoneman 4 months ago.

Not to worry. Its just temporary because of the strong antibiotic. Once you are back to normal everything will stabilize. Answered by Bennie Mickelberry 4 months ago.

5.6 is within the normal range for WBCs Answered by Wanda Weiszbrod 4 months ago.

Not to worry, that means your body is clearing the infection. Answered by Tora Cuttitta 4 months ago.


Where can I find outdated/former package inserts for medications?
We are trying to settle a debate about whether or not daptomycin used to have a stability of seven days when in a pvc bag. Everyone says I'm crazy because it's currently listed as 48 hrs, but I know the package insert was very recently revised. I just want to prove I'm the only one who payed... Asked by Xavier Lubinsky 4 months ago.

We are trying to settle a debate about whether or not daptomycin used to have a stability of seven days when in a pvc bag. Everyone says I'm crazy because it's currently listed as 48 hrs, but I know the package insert was very recently revised. I just want to prove I'm the only one who payed attention, but everywhere I search I can only find the up to date one (Which is probably good in every case but mine). Answered by Joanna Loston 4 months ago.

You are mistaken. The amendments to the insert did not change the time the drug is considered stable. Answered by Temika Templet 4 months ago.


Does any body know about a cure for MRSA?
Asked by Hermila Crissman 4 months ago.

Sure: 1) Zyvox 2) Vancomycin 3) Daptomycin 4) Bactrim (if C-MRSA) It's a bacterial infection requiring antibiotics. Answered by Audry Pekala 4 months ago.


What is the best possible cure for MRSA?
I was diagnosed with MRSA on March 11, 2008 therefore I have had it for a little over 9 months I started taking vancomycin and it showed no response within two weeks of infection it had spread from my thighs to both ankles and into my left armpit where it got into the bloodstream 2 weeks after the initial... Asked by Angila Czekanski 4 months ago.

I was diagnosed with MRSA on March 11, 2008 therefore I have had it for a little over 9 months I started taking vancomycin and it showed no response within two weeks of infection it had spread from my thighs to both ankles and into my left armpit where it got into the bloodstream 2 weeks after the initial infection I've taken clindamycin as week and bactrim but to no avail I have had 5 surgeries in the 9 month period almost died because of a cyst dangerously close to my all my internal organs in my abdomin and I have a new cyst on my butt near the initial infection every morning I wake up they get about the size of a quarter and then go away in 2 weeks and the pain can not be masked by advil or any over the counter painkillers that will not cause drowsiness because I have to go to school I'm currently a junior in high school and need something that will make this go away and most days I can not even attempt to sit Answered by Cleopatra Carmony 4 months ago.

There are other antibiotics for MRSA, particularly Zyvox, daptomycin. Ask your doctor. Answered by Samuel Dickey 4 months ago.


Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
091039/001 DAPTOMYCIN DAPTOMYCIN POWDER/INTRAVENOUS 500MG per VIAL
202857/001 DAPTOMYCIN DAPTOMYCIN POWDER/INTRAVENOUS 500MG per VIAL
203797/001 DAPTOMYCIN DAPTOMYCIN POWDER/INTRAVENOUS 350MG per VIAL
206005/001 DAPTOMYCIN DAPTOMYCIN POWDER/INTRAVENOUS 500MG per VIAL

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
021572/001 CUBICIN DAPTOMYCIN POWDER/IV (INFUSION) 250MG per VIAL
021572/002 CUBICIN DAPTOMYCIN POWDER/INTRAVENOUS 500MG per VIAL
021572/003 CUBICIN RF DAPTOMYCIN POWDER/INTRAVENOUS 500MG per VIAL
091039/001 DAPTOMYCIN DAPTOMYCIN POWDER/INTRAVENOUS 500MG per VIAL
202857/001 DAPTOMYCIN DAPTOMYCIN POWDER/INTRAVENOUS 500MG per VIAL
203797/001 DAPTOMYCIN DAPTOMYCIN POWDER/INTRAVENOUS 350MG per VIAL
206005/001 DAPTOMYCIN DAPTOMYCIN POWDER/INTRAVENOUS 500MG per VIAL

Manufacturers

Manufacturer name
Merck Sharp & Dohme Ltd

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