CUBICIN Ressources

Application Information

This drug has been submitted to the FDA under the reference 021572/001.

Names and composition

"CUBICIN" is the commercial name of a drug composed of DAPTOMYCIN.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
021572/001 CUBICIN DAPTOMYCIN POWDER/IV (INFUSION) 250MG per VIAL
021572/002 CUBICIN DAPTOMYCIN POWDER/INTRAVENOUS 500MG per VIAL

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
021572/003 CUBICIN RF DAPTOMYCIN POWDER/INTRAVENOUS 500MG per VIAL
021572/001 CUBICIN DAPTOMYCIN POWDER/IV (INFUSION) 250MG per VIAL
091039/001 DAPTOMYCIN DAPTOMYCIN POWDER/INTRAVENOUS 500MG per VIAL
021572/002 CUBICIN DAPTOMYCIN POWDER/INTRAVENOUS 500MG per VIAL
202857/001 DAPTOMYCIN DAPTOMYCIN POWDER/INTRAVENOUS 500MG per VIAL
203797/001 DAPTOMYCIN DAPTOMYCIN POWDER/INTRAVENOUS 350MG per VIAL
206005/001 DAPTOMYCIN DAPTOMYCIN POWDER/INTRAVENOUS 500MG per VIAL

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Answered questions

Daptomycin for home use.?
My father-in-Law needs extended use (12 weeks or more) of IV Daptomycin, 500 mg/day. He is on Medicare and is in a nursing facility to receive the medication. He would like to go home and receive the medication at home. This increases the expense because he would have to pay for the medication out of... Asked by Gabriela Rynkowski 1 month ago.

My father-in-Law needs extended use (12 weeks or more) of IV Daptomycin, 500 mg/day. He is on Medicare and is in a nursing facility to receive the medication. He would like to go home and receive the medication at home. This increases the expense because he would have to pay for the medication out of pocket. Can it be done at home and what would it cost for each moth of treatment? Answered by Rubi Bartylla 1 month ago.

I'm not aware of an oral form of daptomycin (Cubicin) so he'll have to have IV access maintained or a central line placed so the peripheral IV site doesn't need to changed every 72 hours. IV antibiotic infusion can be done at home if administered by an IV certified home health nurse who is also an RN. Be advised that I speak for one state only. I don't know where your father-in-law resides or what the state nursing practice act there is. It's entirely possible that in his state LPNs may administer IV antibiotics and this in their scope of practice. If so, this is less costly than having an RN handle it. There are home infusion companies that can arrange everything. Speak to his social worker/case manager at the nursing home and/or speak to a Medicare representative and find out exactly what his options are. These are your two best sources of information and help. For now I can tell you that daptomycin may be administered at home and since his dose is 500mg, the Mini-bag system made by Baxter can be used. The availability of a specific infusion such as Cubicin, depends on the Medicare formulary in his state and his plan benefits under Part D. Under Part D, he may need to pay out-of-pocket for supplies and home administration but it's more important to find out if the med is covered. But as I said, speak to one or both the sources I mentioned. This isn't the right place for your question. I'm just not a case manager or insurance rep, and that's who you need to be talking to. Or he could make things easier and remain in the nursing home until the infusion protocol is completed. Speak to both his case manager AND Medicare today! Answered by Ola Cheater 1 month ago.


I NEED AN ANSWER ON A MEDICATION & THE SIDEAFFECTS?
DAPTOMYCIN 465MG IN 100ML IV Asked by Alla Ruck 1 month ago.

Call a pharmacist they know all about medications. Don't ask someone on here ! Answered by Iluminada Gorglione 1 month ago.

Ummm I think the side effect are blood creatine phosphokinase increased, rhabdomyolysis, skin exfoliation, rash erythematous, fall, rash, pruritus, erythema, myositis, xerosis, skin ulcer. If you don't know what some are just look them up. :] Answered by Shauna Wieben 1 month ago.

pain, swelling, or redness at the injection site; nausea; vomiting; mild diarrhea; constipation; headache; dizziness; or trouble sleeping Answered by Magan Slonski 1 month ago.


Where Can I Find Resources On Recovery From Antibiotic Therapy?
I was diagnosed with MRSA in November of 2011 and had surgery to remove the abscess (incision and drainage). While in the hospital, I was on 1750mg of Vancomycin a day. The MRSA returned in January of 2012 and I was put on 375mg of cubicin intravenously daily for three weeks. I was then plagued by a mystery... Asked by Therese Danes 1 month ago.

I was diagnosed with MRSA in November of 2011 and had surgery to remove the abscess (incision and drainage). While in the hospital, I was on 1750mg of Vancomycin a day. The MRSA returned in January of 2012 and I was put on 375mg of cubicin intravenously daily for three weeks. I was then plagued by a mystery illness where I was on 1800 mg of clindamycin for a while, then 1200mg of Zyvox every day for about a month. Finally, I was admitted to the hospital because the mystery illness was starting to shut down my kidneys and a very painful lump formed. The doctors first thought it might be MRSA, so they gave me 2 bags of vancomycin a day, which I believe was a total of 2000mg a day. When they discovered that it was actually gram negative bacteria, they added 2 bags of ceftazidime a day, which I believe might have also been 2000 mg a day. (I took pics of the bags because I was on a ton of dilaudid and wanted to make sure I could explain what medication I was on if I had to.) I was in the hospital for 6 days total in July of 2012. I received 2 bags of antibiotics a day for the first 2 days, then 4 bags a day for the next 4 days. Turns out the bug that nearly killed me was an e.coli skin infection. Since then, I have been MRSA and e.coli free, but I find it hard to fight off simple infections. For example, little kids get ear infections...not adults. I just got another minor skin infection from shaving, and I'm currently on 1500mg of augmentin daily. Where are the resources online where I can do some research into how to help my body recover from being beaten first with so much infection, and now with antibiotics? I understand that sleep is the best way to recover, but I want to know more about why taking such massive doses of antibiotics really messes you up and maybe what kind of recovery time to expect. Any help would be great! Thanks! Answered by Al Alcantar 1 month ago.

The main problem with antibiotics is that, along with whatever they're meant to kill, they kill other things too and those other things are important. Beneficial bacteria on your skin are just as important as your skin itself for fending off harmful bacteria and bacteria in your gut help digest nutrients and make vitamins. Take probiotic supplements/food, like yogurt with active cultures, and don't over-wash. You need to get your microbe flora back to normal. Answered by Krystal Wieberg 1 month ago.


Need help about staph..very depressed...?
Hi i am 28 yr old male...I have staph infection in my scalp for about 5 yrs now. first it spread all over my scalp and now to my beard..I havent fallen sick in a major way (from some of the news reports that I read and i dont know how I got it) but I am very tired of having this infection around. There are just so... Asked by Deneen Verkuilen 1 month ago.

Hi i am 28 yr old male...I have staph infection in my scalp for about 5 yrs now. first it spread all over my scalp and now to my beard..I havent fallen sick in a major way (from some of the news reports that I read and i dont know how I got it) but I am very tired of having this infection around. There are just so many sores on my head and they are painful all the time. I cant work properly and cant study either, because Im in pain. Plus Im worried I will spread this to other people (you can only wash your hands so many times). I have gone to 6 dermatologists, 5 of them put me on tetracycline, but everytime I was done with my oral course, the infection would come back with a vengeance. The 6th doc put me on muciprocin, omicef and clindamycin, which helped for a month (it was the happiest month of my life), and these sores are back again....Im very depressed. I heard there is a new antibiotic called cubicin...is that any good? Please help. Thanks Answered by Jean Allerton 1 month ago.

Medical experts are repeatedly reporting that staphylococcus, a common bacteria that causes infections is becoming increasingly resistant to antibiotics. Penicillin is now nearly useless against staph...overuse of the drug has fuelled resistance, a process in which the rapidly evolving "bug" simply learns how to evade the drug's fire-power. The Centers for Disease Control indicate that more costly and more powerful antiobiotics are having to be used to "battle bugs". In 2003, the American Journal of Gastroenterology published an entire supplemental issue dedicated to the use of probiotics in disease treatment. This journal, along with many other studies provide evidence of the health benefits of probiotics, some of which include: resistance to viral infections, prevention of treatment of inflammatory bowel disease, resistance to urinary tract and bladder infections, reduction of colon cancer, etc. According to Frank Painter, Doctor of Chiropractic Medicine, probiotics appear to work through a variety of mechanisms, from decreasing pathogen adherence to the intestinal wall to stimulating the systemic immune response. Dr. Painter recommends Optiflora to ALL of his patients, from infants to seniors. This two-product system uses new technology to protect beneficial microflora during the rigors of shipping, storage, and the acidic journey through your stomach. This system includes Probiotic (Bifidus & Acidophilus...microflora) + Prebiotic (FOS...food source for microflora). Patented guaranteed delivery of 500 million microflora to intestines. Hope this is helpful and feel free to contact me for the website. Answered by Margaret Ricke 1 month ago.

Hi, I think you have to go to your doctor and have him take a scraping and a swab of your scalp. You may have develop an infection with a different type of organism. The problem with treating bacteria is that they are continually developing resistance to the antibiotics used today, mainly due to people not finishing their course. They stop taking it because they feel better. You may also have a dermatology problem which is causing you to continually develop sores on your scalp. You could have a fungal infection of some sort or you may have more than 1 organism present. If your doctor prescribes another course of antibiotics ask him for a longer course and some antibiotic cream to apply directly to the sores. Some infections need a longer treatment regime. If its not long enough it often just stuns the organism and they eventually fight back and develop resistance to that antibiotic. Make sure he takes samples form your scalp, he can't just keep treating it without making sure it is the same organism. Hope you feel better soon. Answered by Clemente Bittinger 1 month ago.

5 years!!! Have they cultured the sores lately? You might try an infectious disease doctor. Perhaps a wound culture, a fungal culture, and a viral culture? Maybe they can use cultures to narrow down exactly what antibiotics will target this infection. Also, have you been tested for an immune deficiency? Perhaps IgM, IgA, and IgG plus IgG subclasses blood tests? A routine CBC, and flow cytometry analysis of your white blood cells? Maybe try an immunologist? And it comes back? I heard of a woman who had MRSA living in her bath sponge...maybe if you manage to get rid of it again, replace your sheets and towels and hats and sunglasses and use bleach water on your phones, etc. ---from a hospital lab worker, and the mother of a child with an immune deficiency Answered by Susan Kolkemeyer 1 month ago.

Get some tea tree oil shampoo and conditioner. Also, read the section on building immunity in the Encyclopedia of Natural Medicine by Murray and Pizzorno. A stronger immune system will help you kick these bugs off your skin! It will also do wonders for your health in general! Good luck! Answered by Mitchell Geffken 1 month ago.


What is the best antibiotic?
What is the best (one size fits all) antibiotic & penicillin? Example: If the world ended and we were no longer able to get anymore prescriptions, the best antibiotic and penicillin Asked by Regan Southwood 1 month ago.

There is no "one size fits all antibiotic." The antibiotics that are effective against some of the widest range and/or most resistant of bacteria such as drugs like Zosyn (piperacillin/tazobactam), Timentin (ticarcillin/clavulanate), Tygacil (tigecycline), Teflaro (ceftaroline fosamil), Zyvoxam, Zyvox (linezolid), Cubicin (daptomycin), and many others are excellent (when used properly) but if they were used to treat fairly basic and simple infections that drugs like Keflex (cephalexin), Amoxil (amoxicillin), Pen Vee K (penicillin VK), and other commonly used oral antibiotics could treat then fairly quickly even what are currently the most effective antibiotics would rapidly lose their effectiveness. In many Scandinavian countries they have moved away from using more advanced antibiotics and as a result rarely need them since it is very uncommon for there to be bacteria that can't be treated with basic medication like penicillin, Keflex, or clindamycin. But if I had to pick I would probably say doxycycline or minocycline (unfortunately after they expire they become toxic) however neither is the best of the best, they are both just really good and treat things from acne to anthrax. Answered by Gayle Wesson 1 month ago.

Each antibiotic had its own use. Like for a toothache you would get penicillin. I don't think there is an antibiotic for "anything" Answered by Regena Winsley 1 month ago.

there is no best or one size fits all antibiotic.....i work in a hospital, if there was a "best" antibiotic, we would use it with every person who needed antibiotics...... Answered by Vida Lamarta 1 month ago.

there is no one size fits all antibiotic. antibiotics are for bacterial infections,they do nothing for viruses. antibiotics are specific as to what they can affect. Answered by Kendrick Huang 1 month ago.


Anyone had mrsa cellulitis without recurrences for more than a year?
I have also been doing the hibiclense, health food, nasal swabs, and immune system boosters. I need help with what to ask for at my appointment on Thursday. Asked by Wilbert Kiesz 1 month ago.

I have had reocurring mrsa cellulitis x 4, on and off for 10 months. The abcess comes around day 8 or so. I have had two positive cultures in the past so I know it is mrsa. I have has a negative bone scan. Blood culture came back positive for gram + in the preliminary however there was no growth after 5 days. I have had countless pill and iv antiobiotics. Bactrim worked okay but it came right back. I am in week 5 of 6 of iv cubicin treatments and it is still not gone. Has anyone had similar problem that was able to get rid of it for good? Does anyone know if an MRI would be appropriate? Last time I asked the doctor he said no but I bet if I was his family member I would have my mri. I don't have much faith in doctors right now. I am seeing a different ID doctor this week however I would like to be as educated and informed as possible when I go in to see him. I want to know what tests or antibiotics to ask for. Answered by Bok Koellner 1 month ago.

I have close family members that suffer from mrsa and the way we have kept it at bay is to make sure hands are kept clean and bleach bedding, towels,ect. Bactrim worked well for my kiddo. Keep nails short and clean. Use body scrubs to keep dead skin off and use an antibacterial bodywash. I know how painful it is and how scary it can be. Don't think an MRI would be helpful but if the new Dr does I hope it helps in some way. They may have to do surgery and cut out the abcess. Good luck to you! Answered by Linh Norstrud 1 month ago.

My daughter had a MRSA infection on her eyelid last year. We tried numerous antibiotics for three months before finally getting results with a combination of Bactrim and Refampin. She has been infection free for 7 months now. Hope that helps. Answered by Santo Losada 1 month ago.

There at the instant are not that many buttons while your palms get used to the controllers and which buttons to press exchange into organic like typig or using a bike. prepare prepare prepare! risk is your 4 year old merely spends too a lot time in front of the television. you at the instant are not pathetic. If its that important to you to compete with a 4 year old in video games, then merely prepare for an hour on a daily basis and you'd be waiting to overcome her definitely in a rely of weeks. :-) Answered by Jan Digesare 1 month ago.


Please Help with MRSA questions!!?
I have been diagnosed with MRSA twice however I believe that I have had it 4 times. I have done the antibiotics, nasal cream and special bodywash. I am starting to get another spot on my back in the same spot that the last one was in. I called my PCP and they can't get me in till Monday. Should I go the the... Asked by Jackson Rende 1 month ago.

I have been diagnosed with MRSA twice however I believe that I have had it 4 times. I have done the antibiotics, nasal cream and special bodywash. I am starting to get another spot on my back in the same spot that the last one was in. I called my PCP and they can't get me in till Monday. Should I go the the ER and see if I should be admitted or just wait for Monday. There are 4 children that live in my house ranging in age from 7 to 16. Please, any advice would be greatly appreciated. Answered by Sammy Balcitis 1 month ago.

Sounds so familiar. I have been fighting with the doctors. I keep getting it back in the same spot and they tell me it is a coincidence or I have a "bum leg". If you have repeat mrsa demand a blood culture and a bone scan or MRI. I had both of these tests. They were negative but if they came up positive, that would have explained the relapse. I have had it 4 x in my right lower leg over 10 months. I am guessing they keep giving me the wrong antibiotic or not leaving me on the right antibiotic long enough. Possibly the test results were wrong. Anyway I am on cubicin daily iv therapy now, it is looking good but I am scared it will come back again after I stop. This drug is one of the newer more aggressive drugs however, no lie, I had to fight with 5 doctors to get it. I have a daughter at home and I am not ready to die. After the 4th relapse I decided I was going to get the best treatment available no matter how many doctors I had to see. If your sore is over a boney area go to the ER today. MRSA can go to the bone and then it is harder to treat. If it is over a muscular area and it if not progressing too rapidly and you don't have a fever you might be okay to wait if you PCP felt it was okay to wait until Monday. email me if I can help - [email protected] Answered by Chaya Shipps 1 month ago.

Once you have MRSA, it doesn't go away forever...it only subsides until the next time it shows its ugly head... If you have no extra meds around the house that you've used before...then I say go to the ER and be seen there...or to a medical aide unit... They will probably start you on a regimen of antibiotics just as a precaution...even though most of the time with MRSA...antibiotics don't help too much...it just tames the infection to where you won't have any symptoms...but be aware that once you have MRSA..you always have it...it never completely goes away... Call your doctor and ask him or her to call a prescription in for you at your pharmacy...it's better to do something now rather than later...especially if there are others living in the same house with you. Answered by Kellye Twiet 1 month ago.

It all depends on the size of the lesion. If it is small you dont have to go ER. I dont think so docotor can call in antibotics for MRSA because to avoid over use of the antibotic which will result in very bad resistent MRSA. Methicillin Resistent Stap Aerus is one type where ur regular pencillin does not work. MRSA is endemic in many places for more than 2 years. Only recently there is public awarness. Only few oral medications works that is bactrim cipro. If you have the lesion that is oozing pus then u can spread the infection. For that untill u see the docotor make sure u wash with Hydrogen peroxide or b-iodine. If you bactroban onit given by the doc from previous visit u may have to apply there. DONT share your towels bedspread with your family member if the lesion is oozing and you should be cover the lesion with gauze and bactroban on it Answered by Louella Laity 1 month ago.

i think of if your niece has no longer had direct touch with this different student she would desire to be fantastic. between the subject concerns with MRSA is that it has now jumped from hospitals to being a community aquired an infection. this is a severe staph an infection as a results of fact a great number of antibiotics are actually much less helpful, subsequently the term "resistent". All different documents published fantastically plenty covers what this micro organism is and what it does. surely, the greater healthy the guy is while uncovered, the greater beneficial the prospect of battling off the an infection or no longer even coming down with it. Immunocompromised (maximum cancers, HIV, diabetics and others) are at superb danger if uncovered. Answered by Racheal Geister 1 month ago.


How do i stop being sick with MRSA staph infection?
hi,Im a 28 yr old female from the usa and Ive had a debilitating mrsa infection every day for 3 yrs.ive felt very sick and have some chronic sepsis from this. with severe symptoms and thought id die a few times. the blisters and scabs leak pus, they do not heal. every day for 3 yrs ive had active infected hot... Asked by Willie Fogg 1 month ago.

hi, Im a 28 yr old female from the usa and Ive had a debilitating mrsa infection every day for 3 yrs.ive felt very sick and have some chronic sepsis from this. with severe symptoms and thought id die a few times. the blisters and scabs leak pus, they do not heal. every day for 3 yrs ive had active infected hot leaking scabs on my skin. its clusters and im very tired all the time and ive been on so many antibiotics for years one after the other and they do nothing to get rid of the infection or lesses it. mine is resistant to the 15 or more types of antibiotics ive been on. and i got some severe side effects from all the strong antibiotics i tried bactrim too on the skin and nostil also in cream and ointment form, dosnt help at all. i tried washing with bleach and water baths, dosnt get rid of it, i tried hibiclens surgical bathing , that dosnt do anything. im so tired, weak, shaky all the time, sweaty, chills, it took down my immune system. i cant focus and my memory and mental function is bad now since i got mrsa i cant work or go about my life because of it, i became a shut in almost and have no energy what can i do? ive been to tons of doctors about this and they dont know what to tell me because each time they prescribe antibiotics it dosnt help, even strong antibiotics they dont admit me to the hospital because the wounds arent deep and my vital signs are okay no high fevers, even tho i feel very sick so im like this and dont know what to do, i hate feeling sick every day and today one of the scabs got worse and its hot to the touch, which theyve been hot most of the time for 3 yrs Answered by Heidi Promer 1 month ago.

Hi, I feel quite sorry for what you have had to go through with this infection. I would recommend that you visit an infectious disease specialist who treat things specifically like HIV, Lyme and MRSA and other resistant infections. Depending on where you are you might have to travel to a large city to see one, and pay quite a bit of money but it may be worth it if it brings you out of your misery. They will likely hospitalize you and put you on broad spectrum antibiotics, only 15 have been tried and there is virtually an endless number of antibiotics. MRSA usually wont respond to beta lactam antibiotics. The ones perscribed the most are vancomycin, teicoplanin, linezolid (Zyvox), and daptomycin (Cubicin). These are not the typical penicillin based antibiotic and Staph has not created a resistance to them as of yet. The trouble is these medications MUST be given slowly (over weeks) and in hospital to prevent serious sideffects, therefore you must demand hospital treatment for this as it is proven serious enough and if you see an infectious disease specialist they will likely get you in asap. Also there are many support groups for people suffer from MRSA simply google some in your area. Hope this helps! All the best. Answered by Elinor Blattner 1 month ago.

Sounds awful. You have my sympathy. Reading your message it occurs to me that you have tried doctors and hospitals so why not give herbs and alternative medicines a try. In the old days wounds were bandaged with plants like sage and garlic which are powerful antiseptics. Try things like vitamins, Yakult and herbs for awhile and get your body clear of these modern day drugs which are so powerful they often cause other problems. There is a lot of alternative medicine advice on line. A few keywords in Google will tell you which herbs are antiseptic, antifungul and antibiotic. Try them in poltice like bandaging. Good luck. Answered by Cathy Millen 1 month ago.


Why are surgical infections so bad, and how are they treated?
I just had knee surgery and my doctors keep checking to see if its infected. They make it sound like that would be the worst thing that could happen. How bad would this be? And how would a surgical infection be treated? Asked by Nga Handerson 1 month ago.

try to relax. the surgeon is just doing his job in making sure your knee heals properly and germ-free. right now your body's immune system is compromised due to it try to heal your knee after surgery. your body is more suspectible to catching an infection right now than it normally would be and your dr just wants to make sure he stays on top of it-this is a good thing. most people that come into the hospital and have had surgery are suseptible to drug-resistant germs. the two most common forms are MRSA (Methicillin-resistant Staphylococcus aureus ) and VRE ( Vanocomycin-resistant Enterococci ). both of these illness are hard to treat b/c they are resistant to most antibiotics. once you have come into contact with these germs-they stay with you. The only time you can spread it to others is when the germ is "active" within your system-other times it lies dormant causing no harm. whenever you come to the hospital they will put you on what is called "contact precautions". this means that anyone that enters your room will have to wear gloves and a special type of paper gown to prevent the germs from spreading onto their clothing and spreading to others once they leave your room. handwashing is the best prevention of spreading either germ. to treat them-high doses of heavy duty antibioitics is given via I.V. for the MRSA-usually vancomycin is used. for the VRE-zyvox, Synercid, or Cubicin is used. these are given about every 8 hours for several days until the germ is declared no longer active in your system. i would not be too worried about this as it sounds like your surgeon is doing an awesome job at making sure you stay healthy while your knee heals. good luck to you Answered by Fatima Bubert 1 month ago.

After any surgery, infection is a risk. The hospital personnel are just doing their jobs to make sure you have a smooth recovery without any complications. Infection after surgery is more serious because your body is more susceptible. Please don't worry. Signs of infection are redness and swelling at the surgical site, skin is hot to the touch, and fever. The infection is treated with antibiotics. Answered by Armando Fadel 1 month ago.

One of the major problems with infection is that the kind you are finding more and more often is MRSA which is an antibiotic-resistant staph infection. People are vulnerable to these in hospitals. It's one of the major new concerns in healthcare ( i know because i work in a hospital and it's all they freakin talk about). As to how it's treated depends on if it's MRSA (or a similar strain). Likely scenario is an iv antibiotic with close follow-up. Answered by Maryanne Saltzgaber 1 month ago.


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