CIPROFLOXACIN EXTENDED RELEASE Ressources

Application Information

This drug has been submitted to the FDA under the reference 077417/001.

Names and composition

"CIPROFLOXACIN EXTENDED RELEASE" is the commercial name of a drug composed of CIPROFLOXACIN and CIPROFLOXACIN HYDROCHLORIDE.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
077417/001 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 212.6MG and EQ 287.5MG BASE
077701/001 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 425.2MG and EQ 574.9MG BASE
077701/002 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 212.6MG and EQ 287.5MG BASE
077809/001 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 425.2MG and EQ 574.9MG BASE
078166/001 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 425.2MG and EQ 574.9MG BASE
078166/002 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 212.6MG and EQ 287.5MG BASE
078183/001 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 212.6MG and EQ 287.5MG BASE
078183/002 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 425.2MG and EQ 574.9MG BASE
078712/001 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 212.6MG and EQ 287.5MG BASE

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
021473/001 CIPRO XR CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 212.6MG and EQ 287.5MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
077417/001 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 212.6MG and EQ 287.5MG BASE
021473/002 CIPRO XR CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 425.2MG and EQ 574.9MG BASE **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
077701/001 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 425.2MG and EQ 574.9MG BASE
021554/001 CIPRO XR CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ ORAL 212.6MG and EQ 287.5MG BASE
077701/002 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 212.6MG and EQ 287.5MG BASE
021554/002 CIPRO XR CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ ORAL 425.2MG and EQ 574.9MG BASE
077809/001 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 425.2MG and EQ 574.9MG BASE
078166/001 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 425.2MG and EQ 574.9MG BASE
078166/002 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 212.6MG and EQ 287.5MG BASE
078183/001 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 212.6MG and EQ 287.5MG BASE
078183/002 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 425.2MG and EQ 574.9MG BASE
078712/001 CIPROFLOXACIN EXTENDED RELEASE CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE TABLET, EXTENDED RELEASE/ORAL 212.6MG and EQ 287.5MG BASE

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Answered questions

Does anyone know if its okay to take depakote extended release after the expiration date which is dec 2006?
i know someone who is taking depakote extended release tablets and they expired in december 2006 is it okay or safe to take them now in march 2007 three months from the expiration date. Asked by Mistie Doerner 1 month ago.

It is never a good idea to take meds after the expiration date. For most drugs, they just become ineffective. For some drugs, they change chemical makeup & can become dangerous or poisonous. Make sure that it is the manufacturers expiration date for the drug & not just the expiration of the prescription which are most often 2 different things. Answered by Virgilio Zibert 1 month ago.

usually, the medication is okay after the expiration date for a little while, but the effect lessens as time goes on. Call a pharmacist to make sure. Answered by Kiersten Kimm 1 month ago.

To my knowledge the one medication NOT to take past an expiration date is antibiotics...Im sure it is fine. Ive taken Zoloft way past the exp date Answered by Fatimah Saxon 1 month ago.


I have some minor kidney problem tha course pain at my abdoment.?
I had some test but the results shows no big problem but some infection only. My doctor prescribed these drags ciprofloxacin and cataflam for 10 days yet I am not okey.Iam living in deeveloping country where there is poor medication , what do you think I can do to aviod further continuetion of this proble Asked by Emilio Verhaeghe 1 month ago.

Ciprofloxacin is an antibiotic used to treat or prevent certain infections caused by bacteria. Ciprofloxacin is also used to treat or prevent anthrax in people who may have been exposed to anthrax germs in the air. Ciprofloxacin extended-release (long-acting) tablets are used only to treat certain types of urinary tract infections. Ciprofloxacin is in a class of antibiotics called fluoroquinolones. It works by killing bacteria. Antibiotics will not work for colds, flu, or other viral infections. Diclofenac is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints), rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), and ankylosing spondylitis (arthritis that mainly affects the spine). Diclofenac immediate-release (short-acting) tablets are also used to treat painful menstrual periods and pain from other causes. Diclofenac is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation. Please conduct Urinalysis and Urine culture at a clinical laboratory. Consult an Urologist. Please see the web pages for more details on Ciprofloxacin and Diclofenac (generic name) Cataflam (brand name) Answered by Annie Goyen 1 month ago.

There are alot of causes your kidneys would be hurting. The 2 so much average are infections, and kidney stones. Sometimes, when you've got ate up plenty of bloodless beverages, or pops, it could actually motive your kidneys to harm. If your urine is darkish, has a bad scent, or may be very foamy, it would be indicators of contamination. If it's cloudy, has a redish tint, or burns while you urinate, it would be stones. Both nevertheless demands to be looked at through a health care provider. It will also be checked through practical lab paintings( bloodwork and a urine pattern). It is a well concept regardless that, meanwhile for any symptom, to put off the pops and drink alot of water, and/or cranberry juice. If you do not just like the style, you'll be able to get cranapple, crangrape, even cranberry-strawberry. It is helping to flush out the method and eliminate one of the crucial pollution. I have had each issues, plus kidney failure, for virtually ten years, so I do recognise slightly bit at the area. see a health care provider earlier than it will get worse. You could no longer suppose the ache that may ultimately arise if the hindrance is not looked after correctly and speedily. Answered by Monty Toelkes 1 month ago.


If ciprofloxacin is crushed up and consumed, will it damage your body?
I know that it is extended release and crushing it up gives you too much medication at one time, but is that still ok to do or does it damage your body? If it does please send me a link to the site. One that says something other than crushing it up gives you too much medication at one time. Please help me out Thank... Asked by Anisha Suderman 1 month ago.

I know that it is extended release and crushing it up gives you too much medication at one time, but is that still ok to do or does it damage your body? If it does please send me a link to the site. One that says something other than crushing it up gives you too much medication at one time. Please help me out Thank You. Answered by Brandie Driedric 1 month ago.

Its not particularly hurtful. It just makes the drug less effective since the level of drug in your body will be out of whack. Ciprofloxacin is a safe drug with few side effects if taken appropriately. Whats the point of spending extra money on the extended release kind if you are going to crush it up? Answered by Dorathy Burnaugh 1 month ago.


What Are Some After Affects Of Taking Cipro *?
Took Cipro For Uti , Taken Twice a Day For 7 Dayss . It Has Been 3 Dayss Sice & Nw im Having Nausea When Hungry , Cramps Tht Got Dwn 2 Knees and Even To My Feet, Fatigue , Headaches , back pain, gas , abdominal discomfort boob soreness, watery mouth , knoot feeling in throat . Symptoms chnge almst Daily . Also... Asked by Keira Groshong 1 month ago.

Took Cipro For Uti , Taken Twice a Day For 7 Dayss . It Has Been 3 Dayss Sice & Nw im Having Nausea When Hungry , Cramps Tht Got Dwn 2 Knees and Even To My Feet, Fatigue , Headaches , back pain, gas , abdominal discomfort boob soreness, watery mouth , knoot feeling in throat . Symptoms chnge almst Daily . Also having Frequent Urination & Very Little Come Out Unless iHold My Pee 4 a Whle . So Far Have had nothin 2 drink yet 2Day . Had Gas Pains This Morning Which inceased when i layed on my stomach , (eventually went 2 bathroom & passed alot of stool) now im cramping in legs with middle and lower back pain . I tend to self diagnose myself alot and drive myself crazy googling symptom s soo my mother thinks nothin of it and told me to stop "bugging" also have weakness in both arms at different times . Answered by Armida Sniffen 1 month ago.

Ciprofloxacin is used to treat or prevent certain infections caused by bacteria. Ciprofloxacin is also used to treat or prevent anthrax (a serious infection that may be spread on purpose as part of a bioterror attack) in people who may have been exposed to anthrax germs in the air. Ciprofloxacin extended-release (long-acting) tablets are used only to treat certain types of urinary tract infections. Ciprofloxacin is in a class of antibiotics called fluoroquinolones. It works by killing bacteria that cause infections. The most frequent side effects of ciprofloxacin include nausea, vomiting, diarrhea, abdominal pain, rash, headache, and restlessness. Rare allergic reactions have been described, such as hives and anaphylaxis (shock). Ciprofloxacin should be used with caution in patients with central nervous system diseases such as seizures, because rare seizures have been reported in patients receiving ciprofloxacin. Ciprofloxacin should be avoided in children and adolescents less than 18 years of age, as safe use in these patients has not been established. Answered by Mel Gravat 1 month ago.

Cipro does have an effect on kidney position (as such a lot antibiotics do) so it could actually slash the efficacy of hormonal start manipulate. If you could have been on start manipulate for a couple of months, you are most of the time quality. If it's your first month on it, you will have room for quandary. If even a couple of days of a month of start manipulate are compromised, then there's a threat you might ovulate and get pregnant. You're most of the time quality, however sooner or later, use condoms/abstinence for the the rest of the month should you must take antibiotics. Answered by Celeste Orndorff 1 month ago.


Why would someone take the medications, Cipro and gantanol?
I"ve had medical problems for years and found these two medications, in the bathroom, that belonged to my roommate. Asked by Alexis Herring 1 month ago.

Bacterial infections, particularly UTI's, are treated with gantanol (sulfamethoxazole) and cipro (ciprofloxacin). However, using these without a valid prescription is at best inadvisable, and at worst, dangerous. Cipro belongs to a class of drugs called fluoroquinolones, which have several serious side effects tied to them, notably seizures and tendon rupture, and drug interactions occur with both drugs, particularly in regards to warfarin. Answered by Cathie Hoisl 1 month ago.

They are for infections. Gantanol is used for the treatment of malaria (in combination with quinine sulfate and pyrimethamine), conjunctivitis (inflammation of the conjunctiva of the eye) due to chlamydia, toxoplasmosis (in combination with pyrimethamine), and urinary tract infections (UTI). Cipro is used to treat different types of bacterial infections. It may also be used to prevent or slow anthrax after exposure. Answered by Francoise Boyers 1 month ago.


Should I take Ciprofloxacin?
I feel burning sensation and frequent urination after sex, my GP did some urinanalysis and found nothing. He sent me to an urologist. I saw him today but I was not too happy with him. He did not seem to listen my problem very well and wrote me ciprofloxacin without really doing any tests or looking at any test... Asked by Nettie Stathopoulos 1 month ago.

I feel burning sensation and frequent urination after sex, my GP did some urinanalysis and found nothing. He sent me to an urologist. I saw him today but I was not too happy with him. He did not seem to listen my problem very well and wrote me ciprofloxacin without really doing any tests or looking at any test results. The urologist has really bad raring in ratemymd but I had to go to him since he was quick to get the appointment. So should I take ciprofloxacin or go see another urologist? My pharmacist told me it is prescribed for urinary tract infection but I remember when I asked the urologist what he thinks his answer was "I don't know, we'll see...let's try cipro". So if it's not a urinary tract infection is there going to be any side effect if I take too many(he prescribed me 42) ciprofloxacin? Answered by Natashia Lagman 1 month ago.

"my GP did some urinanalysis and found nothing." -- Exactly what did your labs say? Was a urine culture also done? What was the result? "The urologist has really bad raring in ratemymd but I had to go to him since he was quick to get the appointment." -- Then do remember that seeing him was your decision. "So should I take ciprofloxacin or go see another urologist?" -- If you weren't happy with the first urologist, by all means see another. You needn't take the Cipro until you're satisfied that you actually need it but don't wait too long to get diagnosed. "So if it's not a urinary tract infection is there going to be any side effect if I take too many(he prescribed me 42) ciprofloxacin?" -- This may be too much medication. You didn't say what the strength is (the 200mg, 500mg, 750mg immediate-tablets or the 500mg or 1000mg extended-release) and you didn't say how often the drug is to be taken but with an uncomplicated UTI (and if you have a UTI, it's uncomplicated and mild to moderate), 250mg by mouth every 12 hours for 7-14 days is typical. But even if you were to take this dosage for 14 days, that's only 28 tabs. Cipro shouldn't be taken more than once every 12 hours no matter what the strength. Hold off on this and see another doctor. To further answer this question, ciprofloxacin (Cipro) is in a class of drugs known as fluoroquinolones which are associated with increased risk of tendinitis and tendon rupture in all ages. Let me remind you what the urologist said to you when you asked what he thought. He said "I don't know, we'll see...let's try cipro". The urologist you saw would have you "trying" this drug for 21 days without knowing if you needed it, without knowing if you had an actual UTI. Answered by Taryn Ridgel 1 month ago.

You will have to take it even supposing you haven't been inflamed. Absolutely! It is an antibiotic that is regularly used on different infections. You aren't going to have any lasting results. It will store your lifestyles if you're uncovered to meningococcemia. It may be very fundamental to be immunized as good. People take days and days valued at of Ciprofloxacin for infections that are a lot much less severe. Please take this significantly. Dont fiddle due to the fact that you're afraid to take one million antibiotic pill. RN x 12 yrs. Answered by Kristan Schink 1 month ago.


Is it OK to crush a 500mg Ciprofloxacin tablet?
I've also heard that crushing tablets will not give the full effect as swallowing them whole. Is this true? Also the brand I'm taking is Ciproxina. It's from Mexico since I live close to there. Asked by Jenniffer Hachez 1 month ago.

I just came back from the dermatologist and he told me to take a Ciprofloxacin 500mg Tablet twice a day for 2 weeks. The problem is that I have a lot of trouble swallowing tablets. It's a tablet, not a pill. There is no capsule or any plastic around it. He said it was OK to crush them, but I've been reading online that it might not be a good idea. I just crushed one right now and put it in some Sunny D Orange Juice. It tasted horrible, but I got some gum right afterwards. I don't fell bad or anything. I'm feeling just fine. So is it okay? Answered by Tawna Lev 1 month ago.

Its ok. Its only xr extended release tablets should not be crushed. Try putting it in a bit of apple sauce. Just don't take it with milk or grapefruit juice Answered by Leatrice Osollo 1 month ago.

Ciprofloxacin 500mg Tablets Answered by Yong Ciubal 1 month ago.

I've had a lot of experience with crushing pills, because I have a small windpipe/body. I had to crush Levaquin tablets (which are in the same antibiotic family as Cipro). I can tell you that the side effects (dizziness) are much worse than just swallowing it whole. What I did was I crushed the antibiotic and I put it in TWO applesauces. I ate the apple sauces slowly over the course of an hour to allow the antibiotic to absorb into my bloodstream slowly. I didn't have so many side effects after doing that. Edit: Be sure to call a pharmacist if you have any questions like this, because they can advise you on the best way to take your meds. TIP: Eat yogurt! I recently got off Cipro a few weeks ago and I have some awful skin infection because of the antibiotic. I would suggest taking Probiotic Pearls (you can find them at WalMart) two hours after taking Cipro. Answered by Maurice Froelich 1 month ago.

No, that is not true, powders are turned into tablets and the tablet disintegrates then dissolves in your body anyway. The reason why tablets are made are to improve compliance because they mask the taste of the powder... Taking drugs with Orange juice, now that is a bad idea... To the idiot who thumbed me down. I am serious. Crushing tablet is OK, but taking tablet with Orange juice is not a good idea. Oranges interact with a lot of drugs. Answered by Merissa Nasalroad 1 month ago.

Crushing them is fine. You can take them with what ever you want. You get the same effect, crushed or not. Answered by Loreen Oehlschlager 1 month ago.


Is medication absorbed in the stomach or small intestine? For example, medication used for bacterial...?
Is medication absorbed in the stomach or small intestine? For example, if someone takes a pill for bacterial lung infection, would the pill be absorbed in the stomach or small intestine? And why absorbed in 1 organ over the other? How does the medication treat the lungs and how is the rest excreted? Thanks! Asked by Oren Sturino 1 month ago.

everything is absorbed from the stomach because it's the first stop unless the drug is enteric coated or delayed release. enteric coated tablets as well as some delayed release products dissolve in the small intestine. some extended release tablets or pellets release drug continually over 8-12 hrs. some tablets are designed to dump 1/2 of the drug in the stomach and 1/2 in the small intestine. drugs that are destroyed by stomach acid or better absorbed in an alkaline pH (stomach pH is about 1.3) would be enteric coated or delayed release. having tablets or capsules dissolve in the small intestine can avoid stomach upset such as is the case with minocin pellets. generic minocycline is absorbed from the stomach and may cause GI upset. antibiotics are absorbed from the stomach unless they specially formulated like minocin pellets. delayed release or extended release allows for fewer doses. one tablet every 12 hrs is easier to remember than one tablet every 6 hrs. antibiotics enter the blood stream and eventually make their way to the lungs where they attack the bacteria. penicillins cause bacteria to synthesis a faulty cell wall which in turn causes the lysis of the cell (death). Erythromycin interferes with aminoacyl translocation while ciprofloxacin kills bacteria by interfering with the enzymes that cause DNA to rewind after being copied, which stops DNA and protein synthesis. penicilins are excreted primarily by the kidneys. minocycline and erythromcyin are excreted primarily by the liver. ciprofloxacin excreted by both liver and kidneys. Answered by Amado Welles 1 month ago.

(both) Most is absorbed in the stomach but some is absorbed in the small intestine. As soon as the med. is put in the mouth the saliva starts to dissolve the chemical and some of the chemical(chem) touches some of the mouth tissue. Any cell membranes will absorb some of the chem and then some is passed on to the blood stream where it spreads throughout the body and to the lungs. As the chem goes down the throat the tissue there absorbs some of the chem and that passes on and so forth. There are blood vessels everywhere is the body and they all pass any chem.throughout the body. These chems filter through the liver which filters out foreign chems. and disposes of them. Some of the chem will pass through the blood stream to the lungs and most will be filtered in the liver and kidneys. Enough of the chem will make its way to the lung to treat the infection, the rest will be passed through the liver, kidneys and the intestines for disposal. Answered by Vivien Walke 1 month ago.

Acidic drugs are absorbed in the stomach because they are in the unionized form and can cross the gastric membrane. Basic drugs are absorbed in intestine since intestinal pH favors the unionized form. Unionized forms of a drug cross membranes, therefore pH of certain areas determines a drugs absorption. Answered by Dorthea Mis 1 month ago.

mostly in the stomache and although im not a doctor, i know that a baby can't drink certain medicine b/c their stomache isnt that well developed yet so they can't absorb the medicine anyways so i would go with that Answered by Ute Felmet 1 month ago.


Which is true?
I'm currently taking Cipro, and I've received contradicting advice from two different doctors. One told me, no dairy whatsoever 6 hours before, and 2 hours after my pill, where another said as long as I dont take the pill with a glass of milk, container of yougurt, or bowl of icecream... it would be okay...... Asked by Ethel Cowper 1 month ago.

I'm currently taking Cipro, and I've received contradicting advice from two different doctors. One told me, no dairy whatsoever 6 hours before, and 2 hours after my pill, where another said as long as I dont take the pill with a glass of milk, container of yougurt, or bowl of icecream... it would be okay... Which is true? because Dairy makes up for 85% of my total diet, and if the latter is true, I don't necessairly have to be almost starving myself throughout the course of this medication Answered by Tiara Fumero 1 month ago.

I assume you are taking dairy products in right meaning (it's food stuff produced from milk), and so first of all balance your meals properly, consuming 85% is too much. Both the doctors are right,first doctor is very clear ...second doctor also meant samething but did not clarify the gap between the medicine & Milk related foods. As cipro binds with Ca+, effectiveness is diminished but if you take dairy product as part of your meal,cipro can be taken along with it because food will prevent the drug binding to ca+. Ciprofloxacin is taken twice a day, you can take extended release tab which is to be taken once a day only. Answered by Lucas Soley 1 month ago.

Chances are, the dose you're taking has enough of a safety factor in it (think of it as a friendly overdose) that it won't matter at all. If it's that big a hurdle for you, I suspect you must have had it prescribed as a twice-a-day dosage. If you give yourself something close to an hour between the morning dose and your breakfast, and an hour between your evening dose and dinner, you can be more than confident. The first doctor is being theoretical, the second practical. Answered by Alfredia Mclernon 1 month ago.

First - how long is the course of medicine? Did both doctors know your diet is 95% milk-based? (Why? That isn't balanced.) I would try a pharmacist or two for advice at a local drugstore. Answered by Desire Ingole 1 month ago.


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