A licensed doctor will try to answer your question for free as quickly as possible. Free of charge during the beta period.
What are some enantiomeric drugs?
For example, Thalidomide has a chiral center and its (s) enantiomer is tertogenic which caused birth defects for women who took it while being pregnant. Any other examples would really help! Thank you
Asked by Wilber Arsham 1 year ago.
Amphetamine (Benzedrine; street amphetamine is also racemic) and dextroamphetamine (Dexedrine) Bupivacaine (Marcain) and levobupivacaine (Chirocaine) Cetirizine (Zyrtec / Reactine) and levocetirizine (Xyzal) Citalopram (Celexa / Cipramil) and escitalopram (Lexapro / Cipralex) Methylphenidate (Ritalin) and dexmethylphenidate (Focalin) Modafinil (Provigil) and armodafinil (Nuvigil) Ofloxacin (Floxin) and levofloxacin (Levaquin) Omeprazole (Prilosec) and esomeprazole (Nexium) Salbutamol (Ventolin) and levalbuterol (Xopenex) Zopiclone (Imovane) and eszopiclone (Lunesta) Answered by Oneida Krier 1 year ago.
Actually Thalidomide under biological conditions racemizes and is a mixture of stereoisomers in the human body. If given in the first trimester of pregnancy it causes horrible birth defects. However Celgene Corp whom I once worked for has found it treats multiple myeoloma a type of plasma cell cancer and much has been done through their research to treat that and myeodysplastic syndromes. I hate them but they have done a great deal in this area of cancer treatment look them up. Many drugs MANY are chiral and only one isomer is of use. Remember cholesterol has 258 streoisomers but only one is the very important steroid that gets such a bad rap. In fact s (+) 4-isobutyryl alpha methyl phenyl acetic acid (adivil) is one enantiomer that is a great nsaid but the other isomer sucks. Answered by Catina Gowler 1 year ago.