Application Information

This drug has been submitted to the FDA under the reference 208418/001.

Names and composition

"CALCIUM GLUCONATE" is the commercial name of a drug composed of CALCIUM GLUCONATE.
It belongs to the class Calcium and vitamin D supplements and is used in Electrolytes (Nutrition)

Answered questions

Origin of calcium gluconate?
Asked by Keena Hafenbrack 5 months ago.

Calcium Gluconate consists of 8 - 9% Calcium combined with Gluconic Acid: -This form of Calcium is poorly absorbed although (unlike other forms of Calcium) the Gluconic Acid component of Calcium Gluconate increases the bioavailability of dietary or supplemental Magnesium. Answered by Natalia Stalvey 5 months ago.

Calcium gluconate and blood transfusion..?
Why is Calcium gluconate indicated to someone receiving 3 or more units of blood products? Thanks.. Asked by Albertha Nippert 5 months ago.

When blood is sitting in a bag somewhere before it's transfused, something needs to be added to it to keep it from clotting. If nothing is added, it would clot up and not be useable for transfusion. Citrate is used for this purpose, which binds calcium in the transfused blood. Calcium is required for the coagulation cascade (clotting). It would interact with various clotting factors, allowing clotting to take place. However, since calcium is bound with citrate, it won't be able to interact with the different clotting factors. So with most of the calcium bound up in the bag of blood, when you put it in the body, you'll be low on calcium. You're essentially putting calcium-free blood back in your body. Therefore, calcium replacement must be done since calcium is a very important element in the body, and calcium gluconate is often used. Answered by Eboni Iraheta 5 months ago.

"How could one let your innocent child die because of religion?" Oh no no no, you've got that wrong. It's not because of our religion, beliefs, whatever, etc. It's because we value pleasing God rather than holding onto a life that is still promised us in another world that is promised to come. -- Revelation 21:4 The reason why we refuse full blood transfusions is because of the commandment that God gave regarding the intake of someone else's blood. -- Acts 15:28, 29 Some persons in the medical and legal professions have recognized that a competent adult has the right to refuse a blood transfusion. But they have held that if parents refuse permission for their child, a transfusion should be forced by court order. This position, however, lacks fundamental consistency and harmony, as pointed out in the journal Forensic Science: “Are we then to assume that the courts are willing to assign a different religion to the children than that of their parents, when statistics show that the overwhelming majority of children are reared and indeed follow the same religious denomination as their parents? Would this also not be as much an infringement of religious rights of the children by the courts as those rights which the court is trying to protect for the adults under the First Amendment [of the Constitution] by denying the transfusion over the adult’s objections? Are the courts not assigning in essence a religion to the children if they deny transfusions on religious grounds for adults and permit them for the children of the same adults?” There is often another gross moral inconsistency in forcing a blood transfusion on a child whose parents have asked that other medical therapies be used. At some hospitals doctors in one room may be forcing a transfusion on an infant. Yet in a nearby room other doctors may be performing legal abortions, ending lives only a few months younger than the child on whom blood is forced ‘to save a life.’ This has led thinking persons to wonder if ‘preserving life’ is always the real issue behind forced transfusions. Answered by Missy Moury 5 months ago.

Each blood bag contains some anti-coagulant so that blood does not clot inside the bag. Most of them catches serum Calcium. So once you transfuse some blood, the calcium in the patient's blood is going down. For 1 bag, there is no problem. The person is supposed to recover that shortage soon. But once you transfuse 3 bags of calcium lacking blood, you have to inject one ampule of Calcium gluconate. Other wise, he will develop hypocalcemia. Answered by Sung Dourado 5 months ago.

Potential complications during blood transfusions: Hypothermia: Hypothermia is often present, mostly as a consequence of shock due to loss of thermal regulation but compounded by intravascular infusion of cold fluids and a cold environment. Warming of crystalloid solutions may be supplemented with blood warming when blood is rapidly infused through a central line and/or when infusion rate is faster than 50 ml/kg/hour (60 mL/min in an adult). Acidosis and coagulopathy are most likely to develop secondary to hypoperfusion and hypothermia and not to the massive blood replacement. Citrate Toxicity: By chelating calcium, citrate prevents clotting in blood products during storage. During massive transfusion, the dose of citrate infused is influenced primarily by the type of blood component and by the rate of administration. The infused citrate is rapidly metabolized and excreted by the liver and kidneys, respectively with bicarbonate being the end product. Citrate toxicity can be manifested by hypocalcemia, neuromuscular or cardiac abnormalities. Laboratory evaluations for acid-base status and ionized calcium are strongly recommended prior to initiation of pharmacological therapy, as calcium overtreatment is associated with significant morbidity or mortality. Hyperkalemia: Potassium leaks out of the red cell during storage (contents of 4-8-mEq content of potassium per red cell unit in a 250-300mL volume). This extracellular potassium load is only a transient effect, because once infused, potassium is taken up by red cell, and/or eliminated by urinary excretion secondary to the bicarbonate production of the citrate metabolism. Most often recipients of massive transfusion become hypokalemic and may require potassium supplementation. Transfusion-associated hyperkalemia may be observed in patients with renal failure with already elevated potassium levels or in neonates receiving rapid or large volume transfusions. In these situations the removal of the extracellular potassium in the blood product might be helpful, but more important is the correction of the underlying clinical condition causing the patient’s hyperkalemia. Answered by Ethelyn Gilham 5 months ago.

Is calcium gluconate OK in pregnancy?
Asked by Karl Flannery 5 months ago.

Calcium gluconate is considered a pregnancy category C, which means that it can have adverse effects on the mother or fetus and that the benefits of its use should outweigh the risks to the mother or fetus prior to its use. However, category C can also mean that there is not enough research about the medication and its effects on pregnancy to draw a conclusion about its safety. i would check with your doctor before taking anything when pregnant. Answered by Bradly Elter 5 months ago.

Calcium Gluconate Pregnancy Answered by Kathyrn Lauth 5 months ago.

u should definitely call ur OB/GYN or PCP for this. there are alot of medications or supplements u cannot take when pregnant. it's best to ask the professionals. Answered by Isidra Mcgranor 5 months ago.

Dosage of calcium gluconate in renal faliure to treat hyperkalemia?
Please mention route of admistration. Asked by Blanca Batliner 5 months ago.

Calcium gluconate is an IV calcium preparation. Give 1 gram at a time. It doesn't actually treat the hyperkalemia it just stabilizes the cardiac membrane to help prevent arrhythmias induced by the excess potassium. Measures should be taken to remove the excess potassium via dialysis or kayexalate. Answered by Ted Schiffelbein 5 months ago.

Why does calcium gluconate reverse arrhythmia in hyperkalemia?
I thought that by blocking potassium channels on the myocytes and lowering potassium would treat arrhythmia? Shouldn't that mean that hyperkalemia = arrhythmia? Asked by Kent Nab 5 months ago.

Calcium Gluconate increases the threshold potential which allows your body to handle the elevated levels of potassium. "Shouldn't that mean that hyperkalemia = arrhythmia?" No. Hyperkalemia simply means that the levels of potassium in your body are elevated. This usually leads to Arrhythmia but not in every case. Arrhythmia can be caused by other things. Answered by Lisabeth Ricco 5 months ago.

What calcium compound (calcium carbonate, calcium gluconate, etc.) is found in vitamin pills?
Particularly Centrum multivitamins if possible :D Asked by Cari Barsness 5 months ago.

First of all,let us understand that calcium n its compounds r not vitamins. They r part of minerals, some of these being essential in larger quantities, some in micro. Calcium per se is not found in Vitamin pills but in vit n mineral combination pills. It can b in the form of carbonate, citrate, gluconate, lactate, dibasic phosphate, hydroxy apatite, galacto lacto bionate, etc., Some others also r there but not so frequently seen. Whichever molecule it is, it is dissociated in to elemental calcium n used by the body. Some r more easily absorbed, some slowly, thats all. Answered by Shirley Veller 5 months ago.

nutrition D facilitates your physique to apply the calcium. Calcium carbonate is the main basic style of calcium, regardless of if this is in simple terms chalk. Calcium Citrate is greater helpful to the physique. Answered by Essie Waithe 5 months ago.

What is the rationale for giving calcium gluconate to treat hyperkalemia?? How does it treat it, and do you put your patient at risk for hypercalcemia? Asked by Jamie Goetsch 5 months ago.

Calcium gluconate acts as a diuretic when a patient is not on diuretics. It aids in treating hyperkalemia without causing hypercalcemia if given at the right dose. This is why when it is given CBC blood test are done 4hrs after giving the medication so adjustments can be made to ensure not to much or to little is being given. Answered by Senaida Maas 5 months ago.

Dear phattygirl, Calcium is use in Hyperkalemia for the following reasons 1.- It reduces the risk of ventricular fibrillation caused by hyperkalemia. 2.- It increases the threshold potential 3.- It thus restores the normal gradient between the threshold potential and the resting membrane potential, which is elevated abnormally in hyperkalemia. Hypercalcemia is prevented by titrating the doses with constant monitoring of ECG changes during administration. In case of need, you can contact me at [email protected] Answered by Clotilde Waddle 5 months ago.

Thanks for asking this question! I too am perplexed with the answer. Dr nearly had heart failure when he read my most recent blood work then gave me EKG and is in utmost danger of having heart failure along with me, evidently. I go for Stress testing this afternoon. Then they will decide what else to do with me!! Hey, I ain't a couch potato, I wasn't fat til about 4 years ago when I went on insulin injections, and I ain't a bit lazy about movements!! So what gives??? Answered by Hayley Javaux 5 months ago.

How do you convert 100 mg of calcium gluconate to milliequivalents?
Asked by Marylynn Almeyda 5 months ago.

Divide 100 mg (0.1 gm) by the molecular mass of calcium gluconate (430.373 gm/mole) to get: equivalents = 0.1/430.373 = 0.000232 equivalents = 0.232 milliequivalents Answered by Sandee Jervis 5 months ago.

Difference between calcium gluconate and calcium chloride?
whats the difference between calcium gluconate and calcium chloride, for body hydration.Whats their indication. and what would be the side effect if the treatment is interchanged with one to another Asked by Scottie Peninger 5 months ago.

Calcium chloride is versus to calcium gluconate Answered by Brittney Leverson 5 months ago.

Calcium chloride is much more soluble in water than calcium sulphate. Answered by Rosella Heilmann 5 months ago.

Calcium Supplement Intolerance?
I am a 58 year old female and I understand I need about 1200 mg of calcium per day. I was taking calcium supplements, but I found I am not able to tolerate the supplements - I suffered from gas, bloating, constipation etc. It is difficult for me to get 1200 on diet alone, so wondering if there are alternative... Asked by Syreeta Curren 5 months ago.

I am a 58 year old female and I understand I need about 1200 mg of calcium per day. I was taking calcium supplements, but I found I am not able to tolerate the supplements - I suffered from gas, bloating, constipation etc. It is difficult for me to get 1200 on diet alone, so wondering if there are alternative supplements without the side effects. Answered by Keith Serini 5 months ago.

If you are allergic to Tums (calcium carbonate) perhaps you could try organic calcium such as calcium gluconate. Most calcium comes from dairy products but there is also a reasonable amount of calcium in almonds, Brazil nuts, walnuts and hazelnuts but not in cashews or peanuts. Sesame seeds are very rich in calcium and calcium fortified soy milk contains about the same amount of calcium as dairy milk. Beans and peas also contain some calcium. Answered by Jeanne Nickles 5 months ago.

a normal everyday balanced diet should do it,there is no need for supplements,milk cheese ,greens, Answered by Siobhan Siami 5 months ago.


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