Application Information

This drug has been submitted to the FDA under the reference 008319/008.

Names and composition

"BUTAZOLIDIN" is the commercial name of a drug composed of PHENYLBUTAZONE.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
008319/008 BUTAZOLIDIN PHENYLBUTAZONE TABLET/ORAL 100MG
008319/009 BUTAZOLIDIN PHENYLBUTAZONE CAPSULE/ORAL 100MG

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
008319/008 BUTAZOLIDIN PHENYLBUTAZONE TABLET/ORAL 100MG
008319/009 BUTAZOLIDIN PHENYLBUTAZONE CAPSULE/ORAL 100MG
084339/001 PHENYLBUTAZONE PHENYLBUTAZONE TABLET/ORAL 100MG
086151/001 PHENYLBUTAZONE PHENYLBUTAZONE TABLET/ORAL 100MG
087091/001 AZOLID PHENYLBUTAZONE TABLET/ORAL 100MG
087260/001 AZOLID PHENYLBUTAZONE CAPSULE/ORAL 100MG
087674/001 PHENYLBUTAZONE PHENYLBUTAZONE TABLET/ORAL 100MG
087756/001 PHENYLBUTAZONE PHENYLBUTAZONE CAPSULE/ORAL 100MG
087774/001 PHENYLBUTAZONE PHENYLBUTAZONE CAPSULE/ORAL 100MG
088218/001 PHENYLBUTAZONE PHENYLBUTAZONE CAPSULE/ORAL 100MG
088863/001 PHENYLBUTAZONE PHENYLBUTAZONE TABLET/ORAL 100MG
088994/001 PHENYLBUTAZONE PHENYLBUTAZONE CAPSULE/ORAL 100MG

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Answered questions

Had an abnormal liver function test result?
Just curious what to expect, i have an appt. tomorrow with my dr., but i don't know what can cause an abnormal test result. any answers plz? Asked by Bobby Landaker 1 year ago.

A host of medications can cause abnormal liver enzymes levels. Examples include: Pain relief medications such as aspirin, acetaminophen (Tylenol), ibuprofen (Advil, Motrin), naproxen (Naprosyn), diclofenac (Voltaren), and phenybutazone (Butazolidin) Anti-seizure medications such as phenytoin (Dilantin), valproic acid, carbamazepine (Tegretol), and phenobarbital Antibiotics such as the tetracyclines, sulfonamides, isoniazid (INH), sulfamethoxazole, trimethoprim, nitrofurantoin, etc. Cholesterol lowering drugs such as the "statins" (Mevacor, Pravachol, Lipitor, etc.) and niacin Cardiovascular drugs such as amiodarone (Cordarone), hydralazine, quinine, etc. Anti-depressant drugs of the tricyclic type With drug-induced liver enzyme abnormalities, the enzymes usually normalize weeks to months after stopping the medications. What are less common causes of abnormal aminotransferase levels? Less common causes of abnormal liver enzymes in the United States include chronic hepatitis B, hemochromatosis, Wilson's disease, alpha-1-antitrypsin deficiency, celiac sprue, Crohn's disease, ulcerative colitis, and autoimmune hepatitis. Though not as common as hepatitis C, hepatitis B can cause chronic liver disease with persistently abnormal liver enzymes. Hemochromatosis is a genetic (inherited) disorder in which there is excessive absorption of dietary iron leading to accumulation of iron in the liver with resultant inflammation and scarring of the liver. Wilson's disease is an inherited disorder with excessive accumulation of copper in diverse tissues including the liver and the brain. Copper in liver can lead to chronic liver inflammation, while copper in brain can cause psychiatric and motor disturbances. Alpha-1-antitrypsin deficiency is an inherited disorder in which the lack of a glycoprotein (carbohydrate-protein complex) called alpha-1-antitrypsin lead to chronic lung disease (emphysema) and to liver disease. Autoimmune hepatitis results from liver injury brought about by the body's own antibodies and defense systems attacking the liver. Celiac sprue is a small intestinal illness where a patient has allergy to gluten and develops gas, bloating, diarrhea, and in advanced cases malnutrition. Patients with celiac sprue can also develop mildly abnormal ALT and AST levels. Crohn's disease and ulcerative colitis are diseases with chronic inflammation of the intestines. In these patients inflammation of the liver (hepatitis) or bile ducts (primary sclerosing cholangitis) also can occur, causing abnormal liver tests. Rarely, abnormal liver enzymes can be a sign of cancer in the liver. Cancer arising from liver cells is called hepatocellular carcinoma or hepatic. Cancers spreading to the liver from other organs (such as colon, pancreas, stomach, etc) are called metastatic malignancies. _________________ Without knowing what levels are elevated & to what degree they are raised, it is hard to say the exact cause. In my case, I once had mildly elevated liver enzymes from taking many Advil to treat a pulled muscle the month prior to my test. Hope this info helps. Good luck Answered by Millard Coufal 1 year ago.

The doctors do certain blood tests to check the liver: (1) The blood liver" enzymes "will show the doctor if there may be damage to the liver cells (2) the blood liver "function" tests will show the doctor how well the liver cells are functioning to do the job they need to to keep the body well (3) The blood "viral "testing to see if a virus has entered the body and has gone to the liver cells and used them to reproduce themselves. No one blood test is 100% accurate. The doctor may do the same tests again to be sure of this...as different things can affect the tests results. If he thinks it is a problem with your liver, he may exam you: he will place his hand in the upper right portion of your abdomen, just under the rib cage and see if he can feel if the liver is enlarged in size. An enlarged liver means that there may be inflammation in the liver that can be caused by a number of different things. If the cause can be found and the inflammation is treated, the liver cells can heal. It is a matter of whether you truly have a liver problem, what the cause is, whether inflammation has developed from the cause, and if the doctor can treat it. It will only become dangerous if there is so much damage to the liver cells that they start to die off... then it is serious...a disease known as Cirrhosis. Some of the causes of liver problems are: alcohol consumption, medication toxification, chemical exposure, fatty liver disease, poison mushroom eatting, hereditary condition, biliary obstruction or malformation, auto immune disease and there are others. I would wait and see what the doctor has to say. Some of the enzyme tests are not just specific to the liver itself and it depends on which ones are elevated to determine this, as some liver enzymes can rise if someone exercised before having the blood testing done. That is just one example. Hope this information is of some help to you. Answered by Georgetta Oshima 1 year ago.


Had an abnormal liver function test result?
Just curious what to expect, i have an appt. tomorrow with my dr., but i don't know what can cause an abnormal test result. any answers plz? Asked by Pauline Meriwether 1 year ago.

A host of medications can cause abnormal liver enzymes levels. Examples include: Pain relief medications such as aspirin, acetaminophen (Tylenol), ibuprofen (Advil, Motrin), naproxen (Naprosyn), diclofenac (Voltaren), and phenybutazone (Butazolidin) Anti-seizure medications such as phenytoin (Dilantin), valproic acid, carbamazepine (Tegretol), and phenobarbital Antibiotics such as the tetracyclines, sulfonamides, isoniazid (INH), sulfamethoxazole, trimethoprim, nitrofurantoin, etc. Cholesterol lowering drugs such as the "statins" (Mevacor, Pravachol, Lipitor, etc.) and niacin Cardiovascular drugs such as amiodarone (Cordarone), hydralazine, quinine, etc. Anti-depressant drugs of the tricyclic type With drug-induced liver enzyme abnormalities, the enzymes usually normalize weeks to months after stopping the medications. What are less common causes of abnormal aminotransferase levels? Less common causes of abnormal liver enzymes in the United States include chronic hepatitis B, hemochromatosis, Wilson's disease, alpha-1-antitrypsin deficiency, celiac sprue, Crohn's disease, ulcerative colitis, and autoimmune hepatitis. Though not as common as hepatitis C, hepatitis B can cause chronic liver disease with persistently abnormal liver enzymes. Hemochromatosis is a genetic (inherited) disorder in which there is excessive absorption of dietary iron leading to accumulation of iron in the liver with resultant inflammation and scarring of the liver. Wilson's disease is an inherited disorder with excessive accumulation of copper in diverse tissues including the liver and the brain. Copper in liver can lead to chronic liver inflammation, while copper in brain can cause psychiatric and motor disturbances. Alpha-1-antitrypsin deficiency is an inherited disorder in which the lack of a glycoprotein (carbohydrate-protein complex) called alpha-1-antitrypsin lead to chronic lung disease (emphysema) and to liver disease. Autoimmune hepatitis results from liver injury brought about by the body's own antibodies and defense systems attacking the liver. Celiac sprue is a small intestinal illness where a patient has allergy to gluten and develops gas, bloating, diarrhea, and in advanced cases malnutrition. Patients with celiac sprue can also develop mildly abnormal ALT and AST levels. Crohn's disease and ulcerative colitis are diseases with chronic inflammation of the intestines. In these patients inflammation of the liver (hepatitis) or bile ducts (primary sclerosing cholangitis) also can occur, causing abnormal liver tests. Rarely, abnormal liver enzymes can be a sign of cancer in the liver. Cancer arising from liver cells is called hepatocellular carcinoma or hepatic. Cancers spreading to the liver from other organs (such as colon, pancreas, stomach, etc) are called metastatic malignancies. _________________ Without knowing what levels are elevated & to what degree they are raised, it is hard to say the exact cause. In my case, I once had mildly elevated liver enzymes from taking many Advil to treat a pulled muscle the month prior to my test. Hope this info helps. Good luck Answered by Loma Debenedetto 1 year ago.

The doctors do certain blood tests to check the liver: (1) The blood liver" enzymes "will show the doctor if there may be damage to the liver cells (2) the blood liver "function" tests will show the doctor how well the liver cells are functioning to do the job they need to to keep the body well (3) The blood "viral "testing to see if a virus has entered the body and has gone to the liver cells and used them to reproduce themselves. No one blood test is 100% accurate. The doctor may do the same tests again to be sure of this...as different things can affect the tests results. If he thinks it is a problem with your liver, he may exam you: he will place his hand in the upper right portion of your abdomen, just under the rib cage and see if he can feel if the liver is enlarged in size. An enlarged liver means that there may be inflammation in the liver that can be caused by a number of different things. If the cause can be found and the inflammation is treated, the liver cells can heal. It is a matter of whether you truly have a liver problem, what the cause is, whether inflammation has developed from the cause, and if the doctor can treat it. It will only become dangerous if there is so much damage to the liver cells that they start to die off... then it is serious...a disease known as Cirrhosis. Some of the causes of liver problems are: alcohol consumption, medication toxification, chemical exposure, fatty liver disease, poison mushroom eatting, hereditary condition, biliary obstruction or malformation, auto immune disease and there are others. I would wait and see what the doctor has to say. Some of the enzyme tests are not just specific to the liver itself and it depends on which ones are elevated to determine this, as some liver enzymes can rise if someone exercised before having the blood testing done. That is just one example. Hope this information is of some help to you. Answered by Marilee Ruggiano 1 year ago.


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