ARIMIDEX Ressources

Application Information

This drug has been submitted to the FDA under the reference 020541/001.

Names and composition

"ARIMIDEX" is the commercial name of a drug composed of ANASTROZOLE.
It belongs to the class Aromatase inhibitors and is used in Antineoplastics (Cancer)

Answered questions

Side effects of arimidex?
Asked by Kris Bridgman 6 months ago.

ARIMIDEX may cause side effects. Some may be serious. Stop taking ARIMIDEX and call your doctor right away if you experience any of the following: Chest pain or shortness of breath; these can be symptoms of heart disease Skin lesions, ulcers, or blisters Signs or symptoms of a liver problem A general feeling of not being well Yellowing of the skin or whites of the eyes Pain on the right side of your abdomen Answered by Pok Maggert 6 months ago.

How long does it take for Arimidex to exit the body
This drug causes me great discomfort in my joints, muscles and bones and I'm stopping it. How long will this side effect last? Asked by Russell Molinski 6 months ago.

Arimidex has an elimination half-life of about 50 hours, which means in 200 hours (~ 8 days) the drug is virtually absent if no further doses are taken. There is a difference though in persistence of the drug and persistence of the symptoms- symptoms can persist long after the drug is totally gone from the body for some drugs. From my experience most patients with muscle & joint complaints are are better within a month after cessation; it is rare to go on much longer, though possible. If symptoms persist much longer you might want to pursue further workup to look for other causes. The Arimidex may not be the only source for your symptoms- it may have uncovered or aggravated a pre-existing condition (not obvious before you started arimidex). God bless, best wishes Answered by Beth Seago 6 months ago.

I took Arimidex, and had to come off it for a month - and side effects still persisted. I think Doctors will tell you this will depend on individuals - and no-one can give you a definite answer, but my favourite doc. says it could be three months or so before everything exits the body. So each day you should find things getting better- I do hope so. Have you asked your doctor if there is another drug you can go on? And have you asked for help with side effects? I have found that some doctors are really helpful - others just dismissive - so I have written a website to prove you are not alone, and perhaps give you some ideas to help make it easier to stick on hormonal drugs. Hope this is helpful, and good luck! Verite R Answered by Shawanda Dilox 6 months ago.

Stopping Arimidex Answered by Bethann Molacek 6 months ago.

How does arimidex affect sexually?
Asked by Daryl Coville 6 months ago.

Arimidex is an aromatase inhibitor, which reduces the amount of estrogen produced in your body after menopause. It is used in women after menopause who have hormone-receptor-positive breast cancer. As of now, scientists are still studying the effects of the drug and still no definite answer as to how it affects the quality of life. Answered by Layla Capracotta 6 months ago.

What happens if you don't drink Arimidex?
My mom had her left breast removed and her womb removed as well. She's taking Arimedex and she says it's too much pain. She wants to know if anybody has self-experiences of them taking the doses required and those who didn't and what happened. She doesn't want to take them, but before she... Asked by Erin Neild 6 months ago.

My mom had her left breast removed and her womb removed as well. She's taking Arimedex and she says it's too much pain. She wants to know if anybody has self-experiences of them taking the doses required and those who didn't and what happened. She doesn't want to take them, but before she discontinues them she wants more information on the cause and effects. Thanks. Answered by Stanford Coen 6 months ago.

Your mom's cancer is estrogen positive (the reason for the Arimidex). If she doesn't take the medicine to control the estrogen in her body it could cause the cancer to recur sooner. As for some of the side effects there can be joint pain such as in the hands as well as irritation and mood swings and even hot flashes to name a couple of other side effects. There are ways to deal with some of those side effects and her oncologist can help her find a safe way to do it without causing more concern for the cancer coming back sooner. I would tell your mom to have a heart to heart discussion with her oncologist and let them know how concerned she is about the side effects. She may want to try Femara which is in the same class of drugs that Arimidex is but the side effects are supposed to be a lot less intense. Answered by Adolfo Symonds 6 months ago.

Is there a generic drug for Arimidex?
Asked by Cecila Crespino 6 months ago.

No, but there are other in the same class as Arimidex, called aromatase inhibitors, Femara and Aromasin. Some may be cheaper depending upon your drug plan. I would imagine tamoxifen is also much cheaper, and that is an alternate to an aromatase inhibitor. If you are having trouble paying there are also some patient assistance programs. But check with your doctor to see if there is an alternative that you could afford if Arimidex is too expensive. Call your insurance and find out what is their preferred medication in this class of drugs. Answered by Carylon Cherubini 6 months ago.

I'm taking Arimidex. If there was a generic version of it, my insurance company would insist that I use it. Answered by Gita Dulek 6 months ago.

Arimidex, also known as Anastrozole or Liquidex, can be best classified as an aromatase inhibitor recommended by medical practitioners all over the globe as adjuvant treatment of postmenopausal women afflicted with hormone receptor-positive early breast cancer; this drug can also be used as a first-line treatment of postmenopausal women with hormone receptor-positive or hormone receptor unknown locally advanced or metastatic breast cancer. It is, however, important to note that Arimidex is not recommended to women of premenopausal endocrine status, and individuals with existing hypersensitivity to Arimidex or any of its excipients. Answered by Marine Boteilho 6 months ago.

Is it dangerous to eat tofu when on arimidex of breast cancer?
Asked by Deann Ocanas 6 months ago.

I've been on Arimidex for almost five years - next month's prescription will be my last! Throughout that time I have eaten tofu; I'm a vegan so it's a regular part of my diet. I have had no recurrences and had no sign of cancer at my check up in January. Soya proteins contain isoflavones that can mimic a weak oestrogen effect. It's not the same as the oestrogen your own body makes though - it is 1,000 times weaker than your own body's oestrogen, but it's this that has led to concerns (and rumour) about soya and oestrogen dependent breast cancer. There is no actual scientific evidence that soya causes, prevents, contributes to or affects the progress of any cancer. There are those in the field who argue that isoflavones may be of help in preventing breast cancer or be beneficial to women who have had breast cancer. There is current research into whether increasing phyto oestrogens in the diet helps to prevent breast or prostate cancer, and a study in 2002 found that women with the highest levels of soya products in their diets had the lowest breast density - higher breast density being associated with higher breast cancer risk. And women with the highest levels of isoflavones in their diet are reported to have significant risk reductions for uterine cancer. Tofu and other soya products are fine in moderation Answered by Refugio Accornero 6 months ago.

No honey it isn't. I am nine years a survivor and I carefully research all my treatments and medication. It floors some of the doctors to deal with a patient who does their homework. Tofu, made from soy, produces a very, very weak estrogen effect. We're talking micro grams here. And I believe it is a different type too. Answered by Adeline Mallahan 6 months ago.

I asked my oncologist about soy products in general while on Arimidex. The advice I received was that current research showed that they were safe, but if they weren't already a part of my diet, then there was no point introducing them. As I personally prefer dairy products, it was recommended that I continue to eat/drink low fat dairy rather than change to soy products. Answered by Queen Rybka 6 months ago.

My oncologist said I can eat any food in moderation. Food does not cause cancer. Answered by Sue Nordberg 6 months ago.

Has anyone been on Arimidex?
thank you everyone that answered. Asked by Ardell Dewyse 6 months ago.

I recently finished my 5 year course of Arimidex. My greatest side effect was joint stiffness, mainly in my knees and ankles - on getting out of bed or getting up from sitting for a long time, I walked like a very old woman for short while. This improved over time, but never completely went away. In the early months I had frequent hot flushes; these too got much less frequent as time went by. For the first six months or so I got frequent and sometimes very severe cramps in my legs and feet at night. Subsequently I got these occasionally. Other than that I didn't have any noticeable side effects. Answered by Bryon Wallie 6 months ago.

My mother began taking Arimidex soon after her surgery but stopped taking it soon after. It caused her massive problems with her joints as well as causing her to develop osteoperosis for which she had to be treated for at a special hospital. Some days it was so bad that she couldn't even walk up the stairs. Side effects will differ between patients because everybody's reactions to medication is different so some may experience milder side effects than other but from what I have experienced both at home and at work, many patients experience side effects that cause great effect to their daily lives. Answered by Lenard Bodak 6 months ago.

Yes, I have been on Arimidex. Different patients get different side effects, but statistics say 95% of us suffer these. If you go to to there is lots of information about medical treatments that help with these. Many of the products and treatments have been developed in France, where they have world's best post cancer survival rate - so they obviously are best at treating these. Good luck - and hope one of suggestions - or more - might help. Verite R Answered by Bud Kaempfer 6 months ago.

Joint pain exactly as lo describes. Hot flushes. General feeling of lethargy/malaise. Can't wait until March when I can stop taking them! Answered by Julia Blankley 6 months ago.

I had breast removed had chemo,estrogen positive. Don't want to take arimidex. What do you think recurrence is
Asked by Johnathan Macapagal 6 months ago.

I also had a mastectomy; I had chemo, radiotherapy and I have been taking Arimidex for almost four years. Your oncologist can give you information about your particular case and what your likely survival statistics are - these are not guarantees of course. As you probably know, much depends on your grade, stage and lymph node involvement. The harsh fact about breast cancer is that it can recur or metastasise at any time, even many years after initial diagnosis and treatment. Most recurrences happen in the first two years after treatment, and after five years you are statistically less likely to have a recurrence. There is no all-clear with breast cancer; no doctor will tell a breast cancer patient that they are cancer-free - they might be, but there is no way to tell. The expression usually used at routine check-ups is NED - no evidence of disease (NED is my favourite word). I'm sure you have your reasons for not wanting to take Arimidex; certainly it can have a few unpleasant side effects, though not everyone gets them. But I chose to take it to minimise the risk of recurrence as far as possible. Answered by Dorsey Abdelaziz 6 months ago.

Why is it that you don't want to take your meds? Are you having side effets? Do they cost too much? There has to be a reason. If you are having side effects, talk to your doc. There's a couple different forms of antiestrogens. Maybe you could find one that doesn't effect you as much. Is the medication too expensive? Ask you doc if there's any way that you can work something out financially or get assistance with paying for the med. I know that without this medication you are much more susceptible to getting cancer again. If you reduce your estrogen, your tumor has nothing to feed off, which makes reccurrance less likely. I can't give you a specific recurrance rate, but I do that studies have shown that those who take antiestrogens are significantly less likely to have recurrance. All that being said, ultimately, the choice is up to you. As a patient, you have the right to refuse any type of treatment. Answered by Ashlee Agamao 6 months ago.

Y don't u want to take the meds. Have u been having bad side effects. My mom is a breast cancer survivor and the drs said that it was very important to take meds after surgery and chemo because u r at a even higher risk of the cancer coming back after an episode. I think you should really take meds. Also did u have plastic surgery. The drs took the fat from my moms stomach and made her a breast they lifted the other 1 so they would match. So in all she got a tummy tuck and a breast lift. Answered by Aleisha Rurup 6 months ago.

I have a dear friend who had her breast removed and she is taking arimidex. Like you she doesn't want to take it, but she knows that if she doesn't take it the cancer can reappear. Have you discussed this with your doctor. He would be the best person to talk to and you know you are getting the right answer to your question. Good Luck and God Bless. Answered by Charise Obermoeller 6 months ago.

For me, the Arimidex is the only thing keeping my cancer under control. Without it, I think I might not be alive. I think I am buying time with it. And, I am glad that I am. Answered by Joette Sueda 6 months ago.

So they took the whole breast. More about your particular situation will help such as if you are post menopausal, obese, how many lymph nodes were biopsied and how many were positive, how healthy you are, Is this the 1st cancer you have had, and if you still have ovaries and a uterus. Answered by Marianna Ybarra 6 months ago.

What is breast cancer survival % rate for follow-up drug(s) vs Arimidex vs no followup drugs?
I have just completed over a year's chemo,surgery,radiation,& chemo again with clean results for treatment for estrogen receptive breast cancer. No mascectomy,but removed 1/2 breast with lumpectomy, leaving a 7 in. scar across chest. I am 64 yrs old and never been sick or operated on before. I cannot find... Asked by Yolando Layng 6 months ago.

I have just completed over a year's chemo,surgery,radiation,& chemo again with clean results for treatment for estrogen receptive breast cancer. No mascectomy,but removed 1/2 breast with lumpectomy, leaving a 7 in. scar across chest. I am 64 yrs old and never been sick or operated on before. I cannot find anywhere where it tells me what the % rate of survival is for Armidex for five years vs NO followup drugs survival rate for five years. Tests seemed to all have been done with comparisons of Arimidex and Tamoxifen, but what is the percentage of survival from using these drugs vs not using them. I do want my best survival rate, but am amazed that I can't get this question answered. My oncologist keeps changing the subject and then I forget and can't get a hold of her for another week or so (Kaiser). Thank you Answered by Jeannetta Opet 6 months ago.

One reason that your oncologist is dancing around this subject is because there is no study that directly compares patients who undergo aromatase inhibitor therapy (such as with Arimidex) to patients who get no therapy at all. This is because medical research has already shown Tamoxifen is better than no treatment at all, so to test whether Arimidex is useful, comparison needs to be made to the standard of care, which is Tamoxifen. It would be unethical to randomize patients to no treatment when we know Tamoxifen is clearly better. So to answer your question, we will have to do it indirectly: We know that patients who receive Tamoxifen therapy, when compared to those who receive no other treatment, have about a 10% improvement in overall survival (e.g. in early breast cancer, 68% vs 57%). When Arimidex is compared to Tamoxifen, the improvement is by another 3-5%. So overall, we can extrapolate that use of Arimidex vs no therapy, is probably by about 13-15%. Keep in mind that the numbers can differ depending on the exact stage of cancer you have, and really, there is no hard data to directly answer what you are asking. Answered by Maryjo Calcutt 6 months ago.

The American Cancer Society hotline might have answers for you or can point you in the right direction. Have you tried Googling the word Arimidex to see what's on the internet? Good Luck & I'm sorry for all you have gone through & are facing. Do you have family or friends assisting you that can go toDr.'s appt. with you to try & resolve this also? Answered by Wenona Crewe 6 months ago.

I don't know they answer but here is another question what was the cause of your cancer was it random chance, environmental or Genetic? If it was the first two then you chance of survival are pretty good from what I have read, but if it is genetic then your chances of developing cancer again (ovarian, second breast cancer) are increased. A genetic mutation of the BRCA1 or 2 gene can increase your chances of cancer by 98% by the age of 50. If you really want to know I would try to contact Huntsman caner institute in Utah they are one of the leading institutions doing research into all types of cancer. They may be able to answerer your questions more fully. Answered by Kandi Kaleiwahea 6 months ago.


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