How Haemophilia is treated?
hi im finding it hard to find different ways of how haemophilia is treated (ALL A, B, C) I know that there is replacement of the VIII Proteins for Type A, but what else is out there? is there any cures?
Asked by Nathan Santoy 6 months ago.
I will answer for Hemophilia A, as that is the only one I have experience with. Treatments are as follows: replacement factor, blood transfusions (rarely used now, but perhaps more common in other countries). For mucousal bleeding, Aminocaproic acid (simply called Amicar) is used, alongside with replacement factor. As for a cure, I'll say no and yes. Technically, hemophilia can be cured through a liver transplant, but the risks involved in the surgery and the requirement for lifelong medications to prevent rejection of the new liver may outweigh the benefits - which is why it's never done. If you so happen to be a hemophiliac and need a liver transplant then that's the only way it would happen. Doctors/medics/researchers are aware, which is why research is done in this area, but not to that extreme... for example, transplanting liver cells, although THIS is still only in research phase. Answered by Sandy Kochheiser 6 months ago.
Question About Nylon?
Nylons are resistant to organisms like fungi, molds and mildew. They have good abrasion resistance. They are good at holding dye. Have high tensil strength. But what are the chemical properties that give nylon these abilitys? & Where can you find this information?
Asked by Kathyrn Poetker 6 months ago.
Nylon is a generic designation for a family of synthetic polymers known generically as polyamides and first produced on February 28, 1935 by Wallace Carothers at DuPont. Nylon is one of the most commonly used polymers.Nylons are condensation copolymers formed by reacting equal parts of a diamine and a dicarboxylic acid, so that peptide bonds form at both ends of each monomer in a process analogous to polypeptide biopolymers. Chemical elements included are carbon, hydrogen, nitrogen, and oxygen. The numerical suffix specifies the numbers of carbons donated by the monomers; the diamine first and the diacid second. The most common variant is nylon 6-6 which refers to the fact that the diamine (hexamethylene diamine) and the diacid (adipic acid) each donate 6 carbons to the polymer chain. As with other regular copolymers like polyesters and polyurethanes, the "repeating unit" consists of one of each monomer, so that they alternate in the chain. Since each monomer in this copolymer has the same reactive group on both ends, the direction of the amide bond reverses between each monomer, unlike natural polyamide proteins which have overall directionality: C terminal → N terminal. In the laboratory, nylon 6-6 can also be made using adipoyl chloride instead of adipic. It is difficult to get the proportions exactly correct, and deviations can lead to chain termination at molecular weights less than a desirable 10,000 daltons (u). To overcome this problem, a crystalline, solid "nylon salt" can be formed at room temperature, using an exact 1:1 ratio of the acid and the base to neutralize each other. Heated to 285 °C, the salt reacts to form nylon polymer. Above 20,000 daltons, it is impossible to spin the chains into yarn, so to combat this, some acetic acid is added to react with a free amine end group during polymer elongation to limit the molecular weight. In practice, and especially for 6,6, the monomers are often combined in a water solution. The water used to make the solution is evaporated under controlled conditions, and the increasing concentration of "salt" is polymerized to the final molecular weight. DuPont patented nylon 6,6, so in order to compete, other companies (particularly the German BASF) developed the homopolymer nylon 6, or polycaprolactam — not a condensation polymer, but formed by a ring-opening polymerization (alternatively made by polymerizing aminocaproic acid). The peptide bond within the caprolactam is broken with the exposed active groups on each side being incorporated into two new bonds as the monomer becomes part of the polymer backbone. In this case, all amide bonds lie in the same direction, but the properties of nylon 6 are sometimes indistinguishable from those of nylon 6,6 — except for melt temperature (N6 is lower) and some fiber properties in products like carpets and textiles. There is also nylon 9. Nylon 5,10, made from pentamethylene diamine and sebacic acid, was studied by Carothers even before nylon 6,6 and has superior properties, but is more expensive to make. In keeping with this naming convention, "nylon 6,12" (N-6,12) or "PA-6,12" is a copolymer of a 6C diamine and a 12C diacid. Similarly for N-5,10 N-6,11; N-10,12, etc. Other nylons include copolymerized dicarboxylic acid/diamine products that are not based upon the monomers listed above. For example, some aromatic nylons are polymerized with the addition of diacids like terephthalic acid (→ Kevlar) or isophthalic acid (→ Nomex), more commonly associated with polyesters. There are copolymers of N-6,6/N6; copolymers of N-6,6/N-6/N-12; and others. Because of the way polyamides are formed, nylon would seem to be limited to unbranched, straight chains. But "star" branched nylon can be produced by the condensation of dicarboxylic acids with polyamines having three or more amino groups. Answered by Beryl Newham 6 months ago.
will 100% nylon mold Answered by Arlene Kerry 6 months ago.
nylon is a plastic that i belived it made from oil. just go to google and type in nylon wiki Answered by August Napper 6 months ago.
I wanted to know if anyone can help, I have just adopted a german shephard that was going to be put down?
Ok I had to add this because of all the comments that I should have let the dog be put to sleep. But low on funds is just a temporary situation for a few weeks. After that I can afford to take him to the vet. I just want something for the next few weeks to help him.
Asked by Stefani Klement 6 months ago.
he has bad hips (which is why they were going to put him down) anyway we cannot afford the high costs of the vet bills for the time being and wanted to know if anyone knows of any over the counter remedies that I can try out. At least to help with the inflammation and pain. He doesn't act like he is in pain but I know it has to hurt. Also his back rear leg sometimes curls under and he walks on his knuckles (hope I am explaining this clearly enough) Answered by Sage Kreidler 6 months ago.
Hang on group! I don't think we are dealing with hip dysplasia but with "DEGENERATIVE MYELOPATHY". This can be mistaken for HD or arthritis. The clue here is the knuckling over on one of the hind legs. That is not HD! Now what is Degenerative Myelopathy. DM is a progressive disease involving the spinal cord. It is thought to be an autoimmune disease. Some of the symptoms : hindquarter weakness, rear limb ataxia, loss of balance, difficulty rising or laying down, knuckling under while walking, limp tail, rear legs crossing under body, rear leg drag etc There is no cure and onset is between 5 and 14 years of age. DM can attack one or both sides of the body. Treatment which may slow the progression is: There are 2 medications which, when used together, can prevent progression or result in clinical remission of DM in up to 80% of affected dogs. These medications are aminocaproic acid (EACA) and n-acetylcysteine (NAC). EACA is usually best given as the solution, using the generic product. This product, while designed for injection, can be mixed with chicken broth to make it palatable and easy to give by mouth. B-Complex Dogs with DM don't absorb B vitamins as well Vitamin C 500 mg Selenium A maximum of 200 micrograms per day is safe for large dogs Vitamin E 2000 IU per day Omega-3 fatty acids 1000 mg of fish oil capsule per day Soybean Lecithin Add 1-2 tsp of soybean lecithin granules to the food twice a day Gammalinolenic acid Borage oil, evening primrose oil or black currant oil, are natural sources of gammalinolenic acid, a fatty acid which is hard to get in the diet. Large dogs should receive 500 mg of GLA twice a day, either as borage oil, evening primrose oil or as black currant oil. Coenzyme Q-10 60 to 100 mg per day The above treatment is from R.M. Clemmons, DVM, PhD Associate Professor of Neurology & Neurosurgery Answered by Matilda Coach 6 months ago.
Unfortunately, shepherds are one of the breeds most prone to hip displasia (rots, dobs and mastiffs also tend to get this). If it has already been diagnosed, this is probably obvious on x ray and that would put it in an advanced stage. Talk to your vet about temporary (very temporary) pain management. They might be able to prescribe a steroid that could reduce swelling. Some online pet med sights also have dietary supplements for improved joint health. Just like with humans, glucosomine condroitin can be helpful to maintain joint health, but sadly, it doesn't reverse the effects of what your dog is experiencing. My advice would be to start saving for the surgery now. It is incredibly expensive, but necessary in such cases. You might be able to contact a local veterinary school who would be willing to work with you, and some vets do take payment arrangements. Sometimes at a teaching hospital, they would be more willing to defer some of the cost. I have rescued so many animals over the years and paid out so much money for their care, so I'm not trying to be callous when I say sometimes you do have to make a decision of quality of life over quantity of life. If surgery is not going to be an option, please don't let the dog suffer. If you are unable to take care of the surgery it needs, you may have to consider that euthanasia would be more humane. Answered by Reid Dunemn 6 months ago.
This dog is in pain and likely to be in pain the rest of his life. If you can't afford to have this dog's hips surgically treated, or don't want to pay a vet for pain meds, it was kind of you to take the dog, but think about the dog living like this day in and day out. There is a product called Dog Gone Pain (DGP) you might be able to find it at pet shops. But it's not cheap. The curling of the foot can be caused by nerve damage. www.fearfuldogs.com Answered by Anthony Dengel 6 months ago.
Bless your heart but do you really feel that you should have adopted this dog that clearly needs medical attention that you can not provide at this time. That said you can give the dog some kind of aspirin, such as bayer. I have a Pet (Dog/Cat) home remedy book I will try and find it if I do, I will send you an email on anything I find that might be of some help to your dog. I do recall that if he is having trouble walking that you can get a towel and use that as a sling to help him out. Answered by Delisa Balcitis 6 months ago.
While it was admirable to save him from the needle, if you knew he had bad hips and also knew you couldn't afford vet bills, why did you take him on? Edit: Don't feel insulted. We all know your heart is in the right place, but any amount of pain, even if it's for a short time, is unjustified. This dog needs quality veterinary care. Answered by Hipolito Riverman 6 months ago.
It was nice of you to "save" this dog, but why did you take this dog KNOWING you couldn't help him? You KNOW he's in pain, he needs Veterinary care, and medication that you can't get in pet stores. That said, for now, try a Glucosamine/Chondroiton supplements with some Vitamin E, and Salmon oil. Look into CareCredit.com for help with getting this dog the Veterinary care he so desperately needs. Answered by Louella Sonoda 6 months ago.
Get out your credit card, or give him back to be put down. You "rescued" him in order to keep him in a life of pain?? without being able to afford his care?? He will at minimum need prescription drugs to deal with the pain. If you don't have the money for that, have him euthanized. Answered by Virgina Tokihiro 6 months ago.
Try talking to a vet over the phone,they might be able to get you some less expensive meds,that is what we did for my friends Shepard who needed allergy pills..Or, I'm sure a German Shepard Rescue Center would be able to send you in the right direction,just please get him some meds! Answered by Erline Wiltrout 6 months ago.
Info about Fibrin Glue Injection?
Well i'm having a Fibrin Glue Injection in my spine tomorrow and nobody has really told me anything about it.I've looked for things about it on the net but I haven't found much help.Would anyone be able to tell me like the risks about it and details about what happens after it, like if I have to have bed rest...
Asked by Machelle Quanstrum 6 months ago.
Well i'm having a Fibrin Glue Injection in my spine tomorrow and nobody has really told me anything about it. I've looked for things about it on the net but I haven't found much help. Would anyone be able to tell me like the risks about it and details about what happens after it, like if I have to have bed rest or whatever... Really anything about the injection is appreciated =] Answered by Nichole Fetner 6 months ago.
Fibrin glue is composed of two separate solutions of fibrinogen and thrombin. When mixed together, these agents mimic the last stages of the clotting cascade to form a fibrin clot. Fibrin glue is available in Europe but is not commercially available in the U.S.; therefore, investigators have extemporaneously compounded their own fibrin glue. Fibrinogen can be obtained from pooled, single-donor, and autologous blood donors and is usually isolated by the process of cryoprecipitation. The thrombin component is generally derived from commercial bovine sources. Some investigators have added calcium chloride and/or antifibrinolytics (i.e., aminocaproic acid, aprotinin) to their preparations. Fibrin glue can be applied using a double-barrel syringe or by spray application. Although fibrin glue has been used in a variety of surgical procedures, it has been especially useful in heparinized patients undergoing cardiovascular procedures requiring extracorporeal circulation, as it does not require an intact hemostatic system to be effective. Fibrin glue also has been evaluated in presealing woven or knitted Dacron vascular grafts. The major drawback to its use is the risk of transmitted serological disease from pooled and single-donor blood donors. The safest preparations use the patient's own blood to prepare fibrin glue. Overall, fibrin glue is a useful adjunct to other methods to control bleeding in selected surgical patients. Answered by Elvina Vitelli 6 months ago.
For anyone that is familiar with Hereditary Hemorrhagic Telangiectasia (HHT) please give me advice?
Also known as "Osler Weber Rendu Disorder".....I've ALWAYS had nosebleeds, so the fact that I'm having them is no big deal. HOWEVER, there is a possibility that I may be pregnant, but it too soon to run out and get a test really. For the past 6 days my nosebleeds have been crazy and erratic....
Asked by Andreas Zoglmann 6 months ago.
Also known as "Osler Weber Rendu Disorder"..... I've ALWAYS had nosebleeds, so the fact that I'm having them is no big deal. HOWEVER, there is a possibility that I may be pregnant, but it too soon to run out and get a test really. For the past 6 days my nosebleeds have been crazy and erratic. Every night while I'm asleep I'm having them and ALL through the day I have them on and off. Could pregnancy be a reason that they are worsening? Thanks in advance for the advice! Answered by Eryn Sache 6 months ago.
Can you list antidotes to the ff substances/drugs?
Anti cholinesterase (cholinergics) Cyanide Narcotics/opioid overdose Thrombolytics Iron Acetaminophen Anti depressants Methotrexate Digoxin Benzodiazepines Lead Warfarin Heparin
Asked by Diane Winokur 6 months ago.
I believe yahoo answers should be the last resort a responsible student must consider in answering questions like this. Anyway, PEACE.... Anti cholinesterase (cholinergics) - atropine Cyanide - sodium thiosulfate Narcotics/opioid overdose - naloxone (Narcan) Thrombolytics - aminocaproic acid (Amicar) Iron - deferoxamine Acetaminophen - acetylcystein Anti depressants - phentolamine Methotrexate - leucovorin Digoxin - Digibind Benzodiazepines - flumenazil Lead - calcium EDTA Warfarin - vit. K Heparin - protamine sulfate Answered by Donna Haymes 6 months ago.
Which of the following is not a carboxylic acid derivative? (EXAM IN 9 HOURS!!!!!)?
a) methyl benzonate b) acetic anhydride c) benzamide d) caprolactam e) oxaloacetic acid PLEASE add if you are sure or not! Thanks a lot!!
Asked by Mica Bruyere 6 months ago.
The chemical interior the drawing is an acid anyhydride - i could wager that it varieties an ester or diester in alcohol. real ketones do lose the carbonyl, besides the undeniable fact that that's regenerated if want be. Acetals are often used to guard carbonyls for the time of synthesis and then they could be reformed Answered by Skye Vig 6 months ago.
Choice (e) IS a carboxylic acid already. The others are all derivatives. Answered by Verline Doore 6 months ago.
What is the molecular or chemical formula for nylon?
I no that there are a lot of different types of nylon so I want the one with the 6-aminohexanoic acid and heat reaction nylon. I have the equation, but i don't no how to condense it. If there's no such thing as what I'm talking about, I want the nylon6,6 chemical formula..
Asked by Isadora Askvig 6 months ago.
Wool and silk are made up of amino acids strung together in a protein. There is no definite chemical formula. Nylon is of two kinds. The first is a polyamide of adipic acid and hexamethylenediamine: -(CO-CH2CH2CH2CH2CO.NHCH2CH2CH2CH2CH2C... The second is from aminocaproic acid: -(NHCH2CH2CH2CH2CO-)x- Some threads are made of cotton or rayon. These are made of polymers of glucose in a particular chemical bonding to make cellulose. Other threads are polyester. This is a polymer of terephthalic acid, HOOC-C6H4-COOH, and ethylene glycol, HO-CH2CH2-OH. Still yet other threads are acrylic, made from polyacrylonitrile, -[CH2CH2(CN)-]x- Answered by Booker Slomba 6 months ago.
To start with DNA is a double helix, although there is also three stranded DNA. The double helix could be circular (the two ends joined) like bacterial, some viral chromosomes and plasmids, or linear like in eukaryotes. It can be supercoiled-imagine the cord of your telephone as the double helix, with its spiral winding corresponding to the winding of the double helix, and twist it again. If proteins are also involved then you can have even higher organization of the DNA. You can have different types of helical geometries (A,B and Z DNA) with B-DNA being thought to be predominant in cells. Answered by Adolph Bull 6 months ago.
(-CO-(CH2)4-CO-NH-(CH2)6-NH-)n All numbers are subscript. There are double bonds between C and O. n is subscript. I couldn't copy and paste it from chemdraw for you unfortunately. (C12H22N2O2)n is the formula for nylon 6,6 Answered by Barton Rattner 6 months ago.
My older dog.. HELP?
i have 13yr old tzu. He has always had funky back legs. As he aged it got worse. He really didnt have much control over his hind end. His legs would wobble and bow in and out. I thought it was lp. My other vet suggested he had a previous back injure and was worried bout it gettin worse. Then i told him how old he...
Asked by Shawnna Manokey 6 months ago.
i have 13yr old tzu. He has always had funky back legs. As he aged it got worse. He really didnt have much control over his hind end. His legs would wobble and bow in and out. I thought it was lp. My other vet suggested he had a previous back injure and was worried bout it gettin worse. Then i told him how old he was and he wasnt worried. But lately His left leg its like he can walk on his and walk with it and move it but its like he cant really control it. He isnt in pain. Never has been. But now he will fall over and sometimes drag his behind. I was wondering what i can do to help him. He is happy eating playful. Tonite he was playin with the other dogs and he can hop on my bed and couch but sometimes i have to help him. anyone have any suggestions. He is loosin mucel mass 2 in his back legs. I do have a appointment for him to be seen but its a few days off. Answered by Tristan Bertsch 6 months ago.
try putting a little warm heating pad on the old man dog that might help his arthritis poor guy, you will have to get him on steroids, and you also can give him a baby aspirin,, i just had to put my 14 teen year old dog down the vet kept telling me he had a pinch nerve in his neck took him to another vet that did ex- rays he had neck cancer and it was spreading fast, boy do i miss the old guy, but just do the heating pad on low and aspirins. good-luck, and give your old dog a hug for me, Answered by Kristan Gaudier 6 months ago.