Application Information

This drug has been submitted to the FDA under the reference 017959/001.

Names and composition

"ADRUCIL" is the commercial name of a drug composed of FLUOROURACIL.

Forms

ApplId/ProductId Drug name Active ingredient Form Strenght
017959/001 ADRUCIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
040023/001 ADRUCIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
081222/001 ADRUCIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
081225/001 ADRUCIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML

Similar Active Ingredient

ApplId/ProductId Drug name Active ingredient Form Strenght
012209/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 500MG per 10ML (50MG per ML) **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**
012209/002 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 2.5GM per 50ML (50MG per ML)
016765/001 FLUOROPLEX FLUOROURACIL SOLUTION/TOPICAL 1%
016831/001 EFUDEX FLUOROURACIL SOLUTION/TOPICAL 2%
016831/002 EFUDEX FLUOROURACIL SOLUTION/TOPICAL 5%
016831/003 EFUDEX FLUOROURACIL CREAM/TOPICAL 5%
016988/001 FLUOROPLEX FLUOROURACIL CREAM/TOPICAL 1%
017959/001 ADRUCIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
020985/001 CARAC FLUOROURACIL CREAM/TOPICAL 0.5%
022259/001 TOLAK FLUOROURACIL CREAM/TOPICAL 4%
040023/001 ADRUCIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
040278/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 2.5GM per 50ML (50MG per ML)
040278/002 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 5GM per 100ML (50MG per ML)
040279/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 1GM per 20ML (50MG per ML)
040279/002 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 500MG per 10ML (50MG per ML)
040291/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
040333/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 500MG per 10ML (50MG per ML)
040334/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 2.5GM per 50ML (50MG per ML)
040334/002 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 5GM per 100ML (50MG per ML)
040379/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
040743/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 1GM per 20ML (50MG per ML)
040743/002 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 500MG per 10ML (50MG per ML)
040772/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 500MG per 10ML (50MG per ML)
040798/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 5GM per 100ML (50MG per ML)
040798/002 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 2.5GM per 50ML (50MG per ML)
076526/001 FLUOROURACIL FLUOROURACIL SOLUTION/TOPICAL 2%
076526/002 FLUOROURACIL FLUOROURACIL SOLUTION/TOPICAL 5%
077524/001 FLUOROURACIL FLUOROURACIL CREAM/TOPICAL 5%
081222/001 ADRUCIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
081225/001 ADRUCIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
087791/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
087792/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
088766/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
088767/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
088929/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
089152/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
089368/001 FLUOROURACIL FLUOROURACIL Injectable/ Injection 50MG per ML
089428/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
089434/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
089455/001 FLUOROURACIL FLUOROURACIL Injectable/ Injection 50MG per ML
089508/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
089519/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 50MG per ML
090368/001 FLUOROURACIL FLUOROURACIL CREAM/TOPICAL 5%
091299/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 2.5GM per 50ML (50MG per ML)
091299/002 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 5GM per 100ML (50MG per ML)
202668/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 500MG per 10ML (50MG per ML)
202668/002 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 1GM per 20ML (50MG per ML)
202669/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 2.5GM per 50ML (50MG per ML)
202669/002 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 5GM per 100ML (50MG per ML)
203122/001 FLUOROURACIL FLUOROURACIL CREAM/TOPICAL 0.5%
203608/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 500MG per 10ML (50MG per ML)
203608/002 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 1GM per 20ML (50MG per ML)
203609/001 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 2.5GM per 50ML (50MG per ML)
203609/002 FLUOROURACIL FLUOROURACIL INJECTABLE/INJECTION 5GM per 100ML (50MG per ML)

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Answered questions

What is the major of chemotherapy agents in anti-cancer drugs ?
Asked by Esteban Doster 1 year ago.

There are many different chemotherapy agents. Different drugs work for different cancers, and they are frequently used in combination. You need to be more specific. Here is a list of chemo drugs: 13-cis-Retinoic Acid 2-CdA 2-Chlorodeoxyadenosine 5-Fluorouracil 5-FU 6-Mercaptopurine 6-MP 6-TG 6-Thioguanine Abraxane Accutane ® Actinomycin-D Adriamycin ® Adrucil ® Agrylin ® Ala-Cort ® Aldesleukin Alemtuzumab ALIMTA Alitretinoin Alkaban-AQ ® Alkeran ® All-transretinoic acid Alpha interferon Altretamine Amethopterin Amifostine Aminoglutethimide Anagrelide Anandron ® Anastrozole Arabinosylcytosine Ara-C Aranesp ® Aredia ® Arimidex ® Aromasin ® Arranon ® Arsenic trioxide Asparaginase ATRA Avastin ® Azacitidine BCG BCNU Bevacizumab Bexarotene BEXXAR ® Bicalutamide BiCNU Blenoxane ® Bleomycin Bortezomib Busulfan Busulfex ® C225 Calcium Leucovorin Campath ® Camptosar ® Camptothecin-11 Capecitabine Carac ™ Carboplatin Carmustine Carmustine wafer Casodex ® CC-5013 CCNU CDDP CeeNU Cerubidine ® Cetuximab Chlorambucil Cisplatin Citrovorum Factor Cladribine Cortisone Cosmegen ® CPT-11 Cyclophosphamide Cytadren ® Cytarabine Cytarabine liposomal Cytosar-U ® Cytoxan ® Dacarbazine Dacogen Dactinomycin Darbepoetin alfa Daunomycin Daunorubicin Daunorubicin hydrochloride Daunorubicin liposomal DaunoXome ® Decadron Decitabine Delta-Cortef ® Deltasone ® Denileukin diftitox DepoCyt ™ Dexamethasone Dexamethasone acetate Dexamethasone Sodium Phosphate Dexasone Dexrazoxane DHAD DIC Diodex Docetaxel Doxil ® Doxorubicin Doxorubicin liposomal Droxia ™ DTIC DTIC-Dome ® Duralone ® Efudex ® Eligard ™ Ellence ™ Eloxatin ™ Elspar ® Emcyt ® Epirubicin Epoetin alfa Erbitux ™ Erlotinib Erwinia L-asparaginase Estramustine Ethyol Etopophos ® Etoposide Etoposide Phosphate Eulexin ® Evista ® Exemestane Fareston ® Faslodex ® Femara ® Filgrastim Floxuridine Fludara ® Fludarabine Fluoroplex ® Fluorouracil Fluorouracil (cream) Fluoxymesterone Flutamide Folinic Acid FUDR ® Fulvestrant G-CSF Gefitinib Gemcitabine Gemtuzumab ozogamicin Gemzar ® GleevecTM Gliadel wafer (t) GM-CSF Goserelin granulocyte - colony stimulating factor (t) Granulocyte macrophage colony stimulating factor (o) Halotestin (t) Herceptin (t) Hexadrol (t) Hexalen (t) Hexamethylmelamine (t) HMM (t) Hycamtin (t) Hydrea (t) Hydrocort Acetate (t) Hydrocortisone Hydrocortisone sodium phosphate Hydrocortisone sodium succinate Hydrocortone phosphate (t) Hydroxyurea Ibritumomab Ibritumomab Tiuxetan Idamycin ® Idarubicin Ifex ® IFN-alpha Ifosfamide IL-11 IL-2 Imatinib mesylate Imidazole Carboxamide Interferon alfa Interferon Alfa-2b (PEG conjugate) (o) Interleukin - 2 (t) Interleukin-11 (o) Intron A® (interferon alfa-2b) Iressa ® Irinotecan Isotretinoin Kidrolase (t) Lanacort (t) L-asparaginase (t) LCR (o) Lenalidomide Letrozole Leucovorin Leukeran (t) Leukine (t) Leuprolide Leurocristine (o) Leustatin (t) Liposomal Ara-C (t) Liquid Pred (t) Lomustine L-PAM (o) L-Sarcolysin (o) Lupron (t) Lupron Depot ® Matulane (t) Maxidex (t) Mechlorethamine Mechlorethamine Hydrochloride Medralone (t) Medrol ® Megace (t) Megestrol Megestrol Acetate (o) Melphalan Mercaptopurine Mesna Mesnex (t) Methotrexate Methotrexate Sodium (o) Methylprednisolone Meticorten (t) Mitomycin Mitomycin-C (o) Mitoxantrone M-Prednisol (t) MTC (o) MTX (o) Mustargen (t) Mustine Mutamycin (t) Myleran (t) Mylocel (t) Mylotarg (t) Navelbine ® Nelarabine Neosar (t) Neulasta (t) Neumega (t) Neupogen ® Nexavar ® Nilandron (t) Nilutamide Nipent ® Nitrogen Mustard (o) Novaldex (t) Novantrone (t) Octreotide Octreotide acetate (o) Oncospar (t) Oncovin (t) Ontak (t) Onxal (t) Oprevelkin Orapred (t) Orasone (t) Oxaliplatin Paclitaxel Paclitaxel Protein-bound Pamidronate Panretin (t) Paraplatin (t) Pediapred (t) PEG Interferon Pegaspargase Pegfilgrastim PEG-INTRON (t) PEG-L-asparaginase PEMETREXED Pentostatin Phenylalanine Mustard (o) Platinol (t) Platinol-AQ (t) Prednisolone Prednisone Prelone (t) Procarbazine PROCRIT ® Proleukin (t) Prolifeprospan 20 with Carmustine implant (t) Purinethol ® Raloxifene Revlimid ® Rheumatrex (t) Rituxan (t) Rituximab Roferon-A® (interferon alfa-2a) Rubex (t) Rubidomycin hydrochloride (t) Sandostatin ® Sandostatin LAR (t) Sargramostim Solu-Cortef (t) Solu-Medrol (t) Sorafenib STI-571 Streptozocin SU11248 Sunitinib Sutent ® Tamoxifen Tarceva ® Targretin (t) Taxol ® Taxotere ® Temodar ® Temozolomide Teniposide TESPA (o) Thalidomide Thalomid ® TheraCys (t) Thioguanine Thioguanine Tabloid ® Thiophosphoamide (o) Thioplex (t) Thiotepa TICE ® Toposar (t) Topotecan Toremifene Tositumomab Trastuzumab Tretinoin Trexall (t) Trisenox (t) TSPA (o) VCR (o) Velban (t) Velcade ® VePesid (t) Vesanoid (t) Viadur (t) Vidaza (t) Vinblastine Vinblastine Sulfate (o) Vincasar Pfs (t) Vincristine Vinorelbine Vinorelbine tartrate (o) VLB (o) VM-26 (o) VP-16 (t) Vumon (t) Xeloda ® Zanosar (t) Zevalin TM Zinecard (t) Zoladex ® Zoledronic acid Zometa ® See? There's a lot of them. Answered by Doloris Lanteigne 1 year ago.

antineoplastics, monoclonal antibodies, Answered by Eladia Oquin 1 year ago.

Please see the webpages for more details on Chemotherapy. Answered by Melynda Mcluckie 1 year ago.


How long after you finished chemo for breast cancer till your periods are regular?
Last Febuary (2006) I finished chemo for breast cancer I took the following chemos:Brand GenericEllence epirubicinCytoxan cyclophosphamideAdrucil 5-Fu, fluorouracilTaxotere docetaxelXeloda capecitabinePlatinol cisplatinVepecid,VP16 etoposideAvastin bevacizumabHow long might it take for my... Asked by Karyn Winkels 1 year ago.

Last Febuary (2006) I finished chemo for breast cancer I took the following chemos: Brand Generic Ellence epirubicin Cytoxan cyclophosphamide Adrucil 5-Fu, fluorouracil Taxotere docetaxel Xeloda capecitabine Platinol cisplatin Vepecid,VP16 etoposide Avastin bevacizumab How long might it take for my cycles to become regular? Answered by Valerie Iacovissi 1 year ago.

As stated, everyone is different... I had bc 2x and the first time I had Cytoxin Oh geesh, I forget the name now..Its also known as the RED DEVIL and something else mixed in there.. It was 9 mos The 2nd time I had Xeloda and something else (sorry...) can't remember and it was like 8 mos. GB hope you are doing okay..I am so far :) Answered by Rhoda Winberg 1 year ago.

I'm not sure the only reason I'm replying is that i had breast cancer and only had radiotherapy, i was then put on tamoxifen and my periods have stopped altogether, i think the best thing to do is ask your surgeon or oncologist next time you have an appointment Answered by Arletta Dulemba 1 year ago.

EVERYONE IS AN INDIVIDUAL BUT I SPEAK FOR MYSELF.....MY PERIOD NEVER CAME BACK AND IT'S BEEN THREE YEARS SINCE THE ND OF CHEMO. Answered by Irena Cubine 1 year ago.


What would happen if you were accidentally injected with a non-prescribed medication?
please answer! Asked by Mike Stana 1 year ago.

What would a doctor do if you were accidentally injected with a very strong medication that was not prescribed to you? Like accidentally being injected with a cancer medication when you don't have cancer. I need an answer as soon as you can. It has not happened to me but I need it for some research I'm doing. Thanks. Answered by Calandra Matelic 1 year ago.

The type of medicine is Adrucil. My scenario is that someone is trying to inject the patient and sticks it in their finger by accident. This has not happened to me or anyone I know, I was just curious. I just need to know what a doctor would do, the side affects, or if it would do anything at all. Thank you for your answers. Answered by Tamatha Shearier 1 year ago.

What if??? Your average doctor doesn't even have such medication on hand to "accidentally" inject you with. Your scenario is so far out of normal practice is it inconceivable. Your doctor doesn't have a $2,000 bottle of Oncovin just laying around his/her office just in case the stray cancer patient that might need Oncovin to treat their disease. Most doctors would not even administer or have such a drug, unless they were Oncologist working in a hospital setting. Answered by Chun Blondin 1 year ago.

You're going to have to be a lot more specific than this. If you're doing research, then you should know that you can't ask an incredibly vague question like this and receive any type of reliable or accurate answer. Your only shot at getting a remotely valid response is if you provide the exact medication in which you are asking about. You should know that all medications have different effects, risks, etc. And even if you do provide the specific name, it doesn't mean you'll get a correct answer. Different things affect different drug side effects, and different people react differently to every drug that exists. For example, if you eat grapefruit while taking xanax, you can intensify the effect of xanax, which could be fatal for some. If you have been taking certain types of pain medication and you take Suboxone or Subutex, you will be thrown into severe withdrawal and could die. Some drugs have completely different effects based upon whether they are taken orally or injected. If you inject suboxone or subutex, you will be thrown into severe withdrawal, period. If you take it orally, under the tongue, as prescribed, the medication will act as it was intended. Some people die the very first time they try ecstacy, while others do not. Some people are allergic to penecillin. Others are not. Certain drugs have off-label uses. For example, certain psychotic drugs, such as schizophrenia medications are prescribed to mentally sound people to help them focus. If you do not have schizophrenia and take this medication, you will have incredible focus and attentiveness. Another example is ADD/ADHD medication, such as Adderall. If someone with ADD takes it, they are calmed down, and are able to focus. If someone without ADD takes it, it has the opposite effect... it's similar to the affects of "speed" and gives them endless energy and drive. Lastly, how in the world would someone be accidentally injected with anything? That is nonsensical. This whole question is nonsensical. This is a very poor question, and I fear for those who may receive the outcome of your "research" ... Answered by Brian Rogge 1 year ago.

This is a very vague question. If you were accidentally injected with a chemotherapy agent it would depend on which one it was, some of them cause severe tissue necrosis if they are not diluted and injected slowly into a "good" vein. There are some agents that can neutralize chemo agents, and there are some drugs that can reverse the side effects of other drugs. But for the most part if you were injected with something it's not comming out of you that is impossible, you just must deal with the side effects of that drug until it clears you system. Answered by Sherry Beames 1 year ago.

(1) Main GOAL of CANCER drugs: to STOP CELL DIVISION in cancerous cells. (2) Whether one has cancer or not, cancer drugs will affect normal cells as well like the ones of your hair. Answered by Elvira Affelt 1 year ago.

Nothing, unless you have an aleragic reaction to it. Then they would give you Benadryll. I am not a Dr. this is just my guess. Answered by Stacy Schieler 1 year ago.


What does fluorouracil cream do?
My podiatrist prescribed fluorouracil cream after treating plantar warts. Asked by Venita Rivelli 1 year ago.

What is the most important information I should know about fluorouracil topical? Do not use fluorouracil topical on skin that is irritated, peeling, or infected or on open wounds. Wait until these conditions have fully healed before using fluorouracil topical. Fluorouracil topical is in the FDA pregnancy category X. This means that it is known to harm an unborn baby. Miscarriage and birth defects have been reported when fluorouracil topical was applied to mucous membrane areas by pregnant women. Do not use fluorouracil topical if you are pregnant or planning a pregnancy. Discuss with your doctor appropriate forms of birth control before starting treatment with fluorouracil topical. Fluorouracil topical is available in a number of strengths and forms (creams and solutions). It is very important that you use the correct form and strength. Contact your doctor or pharmacist if you have questions regarding which product to use. Avoid exposure to sunlight or artificial UV rays (e.g., sun lamps) during and immediately following treatment with fluorouracil topical. Use a sunscreen with a minimum sun protection factor (SPF) 15 and wear protective clothing when sun exposure is unavoidable. Individuals with fair skin may require a sunscreen with a higher SPF rating. (back to top) What is fluorouracil topical? Fluorouracil interferes with the growth of skin cells. Fluorouracil works by causing the death of cells which are growing fastest, such as abnormal skin cells. Fluorouracil topical is used to treat scaly overgrowths of skin (actinic or solar keratoses). Fluorouracil topical may also be used in the treatment of superficial basal cell carcinoma. Fluorouracil topical may also be used for purposes other than those listed in this medication guide. (back to top) What should I discuss with my healthcare provider before using fluorouracil topical? Before using fluorouracil topical, tell your doctor if you: have ever had an allergic reaction to another form of fluorouracil topical (Carac, Efudex, Fluoroplex) or injectable fluorouracil (Adrucil, 5-FU); or have dihydropyrimidine dehydrogenase (DPD) enzyme deficiency. You may not be able to use fluorouracil topical, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. Fluorouracil topical is in the FDA pregnancy category X. This means that it is known to harm an unborn baby. Miscarriage and birth defects have been reported when fluorouracil topical was applied to mucous membrane areas by pregnant women. Do not use fluorouracil topical if you are pregnant or planning a pregnancy. Discuss with your doctor appropriate forms of birth control before starting treatment with fluorouracil topical. It is not known whether fluorouracil topical passes into breast milk. Do not use fluorouracil topical without first talking to your doctor if you are breast-feeding a baby. The safety and effectiveness of fluorouracil topical in patients younger than 18 years of age have not been established. (back to top) How should I use fluorouracil topical? Use fluorouracil topical exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Fluorouracil topical is available in a number of strengths and forms (creams and solutions). It is very important that you use the correct form and strength. Contact your doctor or pharmacist if you have questions regarding which product to use. Clean the area where you will apply fluorouracil topical. Rinse well and dry the area with a towel and wait ten minutes before applying the medication. Wash your hands before and immediately after applying this medication, unless it is being used to treat a hand condition. Apply fluorouracil topical to the affected area with the finger tips or a non-metal applicator, smoothing it gently onto the affected skin. Use enough to cover the entire area with a thin film. Fluorouracil topical should not be applied on the eyelids or in the eyes, nose, or mouth. Use caution when applying fluorouracil topical around the eyes, nose, or mouth. Do not use fluorouracil topical on skin that is irritated, peeling, or infected or on open wounds. Wait until these conditions have fully healed before using fluorouracil topical. Do not cover the area after applying fluorouracil topical. This could cause too much medicine to be absorbed by the body and could be harmful. If a covering is needed, ask your doctor if a porous gauze dressing may be used. A moisturizer or sun screen may be applied 2 hours after fluorouracil topical has been applied. Do not use any other skin products including creams, lotions, medications, or cosmetics unless instructed by your doctor. The reaction of the skin treated with fluorouracil topical may be unsightly during treatment, and sometimes, for several weeks after completion of therapy. Store fluorouracil topical at room temperature away from moisture and heat. (back to top) What happens if I miss a dose? Apply the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and apply only the next regularly scheduled dose. Do not apply a double dose of this medication. (back to top) What happens if I overdose? An overdose of fluorouracil topical is unlikely to occur. If you do suspect an overdose, or if fluorouracil topical has been ingested, call a poison control center or an emergency room for advice. (back to top) What should I avoid while using fluorouracil topical? Do not use other prescription or over-the-counter skin products without first talking to your doctor during treatment with fluorouracil topical. They may interfere with the treatment or increase irritation of the skin. Avoid exposure to sunlight or artificial UV rays (e.g., sun lamps) during and immediately following treatment with fluorouracil topical. Use a sunscreen with a minimum sun protection factor (SPF) 15 and wear protective clothing when sun exposure is unavoidable. Individuals with fair skin may require a sunscreen with a higher SPF rating. (back to top) What are the possible side effects of fluorouracil topical? Serious side effects are not likely to occur. Stop using fluorouracil topical and seek emergency medical attention if you experience an allergic reaction (shortness of breath; closing of your throat; swelling of your lips, face, or tongue; or hives). Fluorouracil topical may cause skin irritation, dryness, scaling or peeling (exfoliation), rash, and other local reactions. Eye irritation has also been reported. If these side effects are excessive or worsen with continued treatment, contact your doctor. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. (back to top) What other drugs will affect fluorouracil topical? Do not use other prescription or over-the-counter skin products without first talking to your doctor during treatment with fluorouracil topical. They may interfere with treatment or increase irritation to the skin. Drugs other than those listed here may also interact with fluorouracil topical. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines. (back to top) Where can I get more information? Your pharmacist has additional information about fluorouracil topical written for health professionals that you may read. (back to top) What does my medication look like? Fluorouracil topical is available as a cream or topical solution with a prescription under the brand names Fluoroplex, Efudex and Carac. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you. Carac 0.5%--cream Fluoroplex 1%--cream Fluoroplex 1%--topical solution Efudex 2%--topical solution Efudex 5%--topical solution Efudex 5%--cream (back to top) Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Answered by Markus Durepo 1 year ago.

Fluorouracil Cream Usp 5 Answered by Abel Reik 1 year ago.

This Site Might Help You. RE: What does fluorouracil cream do? My podiatrist prescribed fluorouracil cream after treating plantar warts. Answered by Hyman Steenrod 1 year ago.


How do drugs halt mitosis?
Maligant tumors are sometimes treated with drugs that halt mitosis, and thus stop the production of new cancer cells. two such drugs, vincristine sulfate and vinblastine sulfate, interfere with the formation of spindle fibers. how could this action halt mitosis?Some drugs can also interfere with DNA... Asked by Lon Barthell 1 year ago.

Maligant tumors are sometimes treated with drugs that halt mitosis, and thus stop the production of new cancer cells. two such drugs, vincristine sulfate and vinblastine sulfate, interfere with the formation of spindle fibers. how could this action halt mitosis? Some drugs can also interfere with DNA synthesis in treated cells. How could this action halt mitosis? Answered by Alexandra Tysarczyk 1 year ago.

Catagories of Chemotherapy Drugs: In general, chemotherapy agents can be divided into three main categories based on their mechanism of action. Stop the synthesis of pre DNA molecule building blocks: These agents work in a number of different ways. DNA building blocks are folic acid, heterocyclic bases, and nucleotides, which are made naturally within cells. All of these agents work to block some step in the formation of nucleotides or deoxyribonucleotides (necessary for making DNA). When these steps are blocked, the nucleotides, which arethe building blocks of DNA and RNA, can not be synthesized. Thus the cells can not replicate because they cannot make DNA without the nucleotides. Examples of drugs in this class include 1) methotrexate (Abitrexate®),2) fluorouracil (Adrucil®), 3) hydroxyurea (Hydrea®), and 4) mercaptopurine (Purinethol®). Directly damage the DNA in the nucleus of the cell: These agents chemically damage DNA and RNA. They disrupt replication of the DNA and either totally halt replication or cause the manufacture of nonsense DNA or RNA (i.e. the new DNA or RNA does not code for anything useful). Examples of drugs in this class include cisplatin (Platinol®) and 7) antibiotics - daunorubicin (Cerubidine®), doxorubicin (Adriamycin®), and etoposide (VePesid®). Effect the synthesis or breakdown of the mitotic spindles: Mitotic spindles serve as molecular railroads with "North and South Poles" in the cell when a cell starts to divide itself into two new cells. These spindles are very important because they help to split the newly copied DNA such that a copy goes to each of the two new cells during cell division. These drugs disrupt the formation of these spindles and therefore interrupt cell division. Examples of drugs in this class of 8) miotic disrupters include: Vinblastine (Velban®), Vincristine (Oncovin®) and Pacitaxel (Taxol®). Answered by Pat Arciba 1 year ago.

Drugs that interfere with the normal progression of mitosis belong to the most successful chemotherapeutic compounds currently used for anti-cancer treatment. Classically, these drugs are represented by microtubule binding drugs that inhibit the function of the mitotic spindle in order to halt the cell cycle in mitosis and to induce apoptosis in tumor cells. However, these compounds act not only on proliferating tumor cells, but exhibit significant side effects on non-proliferating cells including neurons that are highly dependent on intracellular transport processes mediated by microtubules. Therefore, there is a particular interest in developing novel anti-mitotic drugs that target non-microtubule structures. In fact, recently several novel drugs that target mitotic kinesins or the Aurora and polo-like kinases have been developed and are currently tested in clinical trials. In addition, approaches of cell cycle checkpoint abrogation during mitosis and at the G2/M transition inducing mitosis-associated tumor cell death are promising new strategies for anti-cancer therapy. It is expected that this "next generation" of anti-mitotic drugs will be as successful as the classical anti-microtubule drugs, while avoiding some of the adverse side effect Answered by Ariel Tautuiaki 1 year ago.

spindle fibers are used to move the chromosome and orgenelles to opposite sides if you cant dupliccate DNA then you cannot spilt a chromosome for the daughter cells Answered by Madaline Cominotti 1 year ago.


5 days after first chemo treatment?
A friend of mine was diagnosed with colon cancer. He recently went through his first chemo treatment, but it has only been five days after and has already lost all his hair both atop his head and beard. I am concerned because my mother in the past had chemo and her hair did not fall out nearly as quick, it took... Asked by Hugh Rabito 1 year ago.

A friend of mine was diagnosed with colon cancer. He recently went through his first chemo treatment, but it has only been five days after and has already lost all his hair both atop his head and beard. I am concerned because my mother in the past had chemo and her hair did not fall out nearly as quick, it took weeks and it took more than one treatment. Is it possible they are using something stronger than chemo and if so, what questions should he ask his doctors to get the proper answers? It really makes me worried. I know everyone's bodies react differently. But I feel as if five days after is extreme for someone to become fully bald and only after one/first treatment of chemo therapy. Answered by Lakeesha Reando 1 year ago.

My sons both became bald from shear stress after their father died. Now my oldest son is 42 and has gone thru 7 rounds of chemo and lost his beard but the doc said the radiation treatments he is facing next will cause the rest to fall out. Every med they use in chemo reacts diff.he has stage 4 head and neck cancer. Answered by Nikia Hatmaker 1 year ago.

Everyone is different. I woke up with a full head of hair day 10 aftter my first treatment and was bald before I went to bed that night. Answered by Bree Havermale 1 year ago.

Everyone could have a different reaction. Hair could fall out, thin, stay normal. My onco was sure I would lose mine and I didn't lose any to chemo. Doesn't mean it's working any more or less. Poppy, 2 months ago, you said your son was done with chemo and starting radiation....and apparently your son is in chinese prison for drug trafficking, making Ralph Lauren products lol that makes you less than believable. Answered by Joni Rutiaga 1 year ago.


What is the major of chemotherapy agents in anti-cancer drugs ?
Asked by Reatha Benn 1 year ago.

There are many different chemotherapy agents. Different drugs work for different cancers, and they are frequently used in combination. You need to be more specific. Here is a list of chemo drugs: 13-cis-Retinoic Acid 2-CdA 2-Chlorodeoxyadenosine 5-Fluorouracil 5-FU 6-Mercaptopurine 6-MP 6-TG 6-Thioguanine Abraxane Accutane ® Actinomycin-D Adriamycin ® Adrucil ® Agrylin ® Ala-Cort ® Aldesleukin Alemtuzumab ALIMTA Alitretinoin Alkaban-AQ ® Alkeran ® All-transretinoic acid Alpha interferon Altretamine Amethopterin Amifostine Aminoglutethimide Anagrelide Anandron ® Anastrozole Arabinosylcytosine Ara-C Aranesp ® Aredia ® Arimidex ® Aromasin ® Arranon ® Arsenic trioxide Asparaginase ATRA Avastin ® Azacitidine BCG BCNU Bevacizumab Bexarotene BEXXAR ® Bicalutamide BiCNU Blenoxane ® Bleomycin Bortezomib Busulfan Busulfex ® C225 Calcium Leucovorin Campath ® Camptosar ® Camptothecin-11 Capecitabine Carac ™ Carboplatin Carmustine Carmustine wafer Casodex ® CC-5013 CCNU CDDP CeeNU Cerubidine ® Cetuximab Chlorambucil Cisplatin Citrovorum Factor Cladribine Cortisone Cosmegen ® CPT-11 Cyclophosphamide Cytadren ® Cytarabine Cytarabine liposomal Cytosar-U ® Cytoxan ® Dacarbazine Dacogen Dactinomycin Darbepoetin alfa Daunomycin Daunorubicin Daunorubicin hydrochloride Daunorubicin liposomal DaunoXome ® Decadron Decitabine Delta-Cortef ® Deltasone ® Denileukin diftitox DepoCyt ™ Dexamethasone Dexamethasone acetate Dexamethasone Sodium Phosphate Dexasone Dexrazoxane DHAD DIC Diodex Docetaxel Doxil ® Doxorubicin Doxorubicin liposomal Droxia ™ DTIC DTIC-Dome ® Duralone ® Efudex ® Eligard ™ Ellence ™ Eloxatin ™ Elspar ® Emcyt ® Epirubicin Epoetin alfa Erbitux ™ Erlotinib Erwinia L-asparaginase Estramustine Ethyol Etopophos ® Etoposide Etoposide Phosphate Eulexin ® Evista ® Exemestane Fareston ® Faslodex ® Femara ® Filgrastim Floxuridine Fludara ® Fludarabine Fluoroplex ® Fluorouracil Fluorouracil (cream) Fluoxymesterone Flutamide Folinic Acid FUDR ® Fulvestrant G-CSF Gefitinib Gemcitabine Gemtuzumab ozogamicin Gemzar ® GleevecTM Gliadel wafer (t) GM-CSF Goserelin granulocyte - colony stimulating factor (t) Granulocyte macrophage colony stimulating factor (o) Halotestin (t) Herceptin (t) Hexadrol (t) Hexalen (t) Hexamethylmelamine (t) HMM (t) Hycamtin (t) Hydrea (t) Hydrocort Acetate (t) Hydrocortisone Hydrocortisone sodium phosphate Hydrocortisone sodium succinate Hydrocortone phosphate (t) Hydroxyurea Ibritumomab Ibritumomab Tiuxetan Idamycin ® Idarubicin Ifex ® IFN-alpha Ifosfamide IL-11 IL-2 Imatinib mesylate Imidazole Carboxamide Interferon alfa Interferon Alfa-2b (PEG conjugate) (o) Interleukin - 2 (t) Interleukin-11 (o) Intron A® (interferon alfa-2b) Iressa ® Irinotecan Isotretinoin Kidrolase (t) Lanacort (t) L-asparaginase (t) LCR (o) Lenalidomide Letrozole Leucovorin Leukeran (t) Leukine (t) Leuprolide Leurocristine (o) Leustatin (t) Liposomal Ara-C (t) Liquid Pred (t) Lomustine L-PAM (o) L-Sarcolysin (o) Lupron (t) Lupron Depot ® Matulane (t) Maxidex (t) Mechlorethamine Mechlorethamine Hydrochloride Medralone (t) Medrol ® Megace (t) Megestrol Megestrol Acetate (o) Melphalan Mercaptopurine Mesna Mesnex (t) Methotrexate Methotrexate Sodium (o) Methylprednisolone Meticorten (t) Mitomycin Mitomycin-C (o) Mitoxantrone M-Prednisol (t) MTC (o) MTX (o) Mustargen (t) Mustine Mutamycin (t) Myleran (t) Mylocel (t) Mylotarg (t) Navelbine ® Nelarabine Neosar (t) Neulasta (t) Neumega (t) Neupogen ® Nexavar ® Nilandron (t) Nilutamide Nipent ® Nitrogen Mustard (o) Novaldex (t) Novantrone (t) Octreotide Octreotide acetate (o) Oncospar (t) Oncovin (t) Ontak (t) Onxal (t) Oprevelkin Orapred (t) Orasone (t) Oxaliplatin Paclitaxel Paclitaxel Protein-bound Pamidronate Panretin (t) Paraplatin (t) Pediapred (t) PEG Interferon Pegaspargase Pegfilgrastim PEG-INTRON (t) PEG-L-asparaginase PEMETREXED Pentostatin Phenylalanine Mustard (o) Platinol (t) Platinol-AQ (t) Prednisolone Prednisone Prelone (t) Procarbazine PROCRIT ® Proleukin (t) Prolifeprospan 20 with Carmustine implant (t) Purinethol ® Raloxifene Revlimid ® Rheumatrex (t) Rituxan (t) Rituximab Roferon-A® (interferon alfa-2a) Rubex (t) Rubidomycin hydrochloride (t) Sandostatin ® Sandostatin LAR (t) Sargramostim Solu-Cortef (t) Solu-Medrol (t) Sorafenib STI-571 Streptozocin SU11248 Sunitinib Sutent ® Tamoxifen Tarceva ® Targretin (t) Taxol ® Taxotere ® Temodar ® Temozolomide Teniposide TESPA (o) Thalidomide Thalomid ® TheraCys (t) Thioguanine Thioguanine Tabloid ® Thiophosphoamide (o) Thioplex (t) Thiotepa TICE ® Toposar (t) Topotecan Toremifene Tositumomab Trastuzumab Tretinoin Trexall (t) Trisenox (t) TSPA (o) VCR (o) Velban (t) Velcade ® VePesid (t) Vesanoid (t) Viadur (t) Vidaza (t) Vinblastine Vinblastine Sulfate (o) Vincasar Pfs (t) Vincristine Vinorelbine Vinorelbine tartrate (o) VLB (o) VM-26 (o) VP-16 (t) Vumon (t) Xeloda ® Zanosar (t) Zevalin TM Zinecard (t) Zoladex ® Zoledronic acid Zometa ® See? There's a lot of them. Answered by Patrick Grosland 1 year ago.

antineoplastics, monoclonal antibodies, Answered by Lauralee Nikkel 1 year ago.

Please see the webpages for more details on Chemotherapy. Answered by Mazie Capper 1 year ago.


How long after you finished chemo for breast cancer till your periods are regular?
Last Febuary (2006) I finished chemo for breast cancer I took the following chemos:Brand GenericEllence epirubicinCytoxan cyclophosphamideAdrucil 5-Fu, fluorouracilTaxotere docetaxelXeloda capecitabinePlatinol cisplatinVepecid,VP16 etoposideAvastin bevacizumabHow long might it take for my... Asked by Selina Harshbarger 1 year ago.

Last Febuary (2006) I finished chemo for breast cancer I took the following chemos: Brand Generic Ellence epirubicin Cytoxan cyclophosphamide Adrucil 5-Fu, fluorouracil Taxotere docetaxel Xeloda capecitabine Platinol cisplatin Vepecid,VP16 etoposide Avastin bevacizumab How long might it take for my cycles to become regular? Answered by Kristina Edman 1 year ago.

As stated, everyone is different... I had bc 2x and the first time I had Cytoxin Oh geesh, I forget the name now..Its also known as the RED DEVIL and something else mixed in there.. It was 9 mos The 2nd time I had Xeloda and something else (sorry...) can't remember and it was like 8 mos. GB hope you are doing okay..I am so far :) Answered by Oralee Stamatopoulos 1 year ago.

I'm not sure the only reason I'm replying is that i had breast cancer and only had radiotherapy, i was then put on tamoxifen and my periods have stopped altogether, i think the best thing to do is ask your surgeon or oncologist next time you have an appointment Answered by Precious Osei 1 year ago.

EVERYONE IS AN INDIVIDUAL BUT I SPEAK FOR MYSELF.....MY PERIOD NEVER CAME BACK AND IT'S BEEN THREE YEARS SINCE THE ND OF CHEMO. Answered by Shana Smolensky 1 year ago.


What would happen if you were accidentally injected with a non-prescribed medication?
please answer! Asked by Laila Trenholm 1 year ago.

What would a doctor do if you were accidentally injected with a very strong medication that was not prescribed to you? Like accidentally being injected with a cancer medication when you don't have cancer. I need an answer as soon as you can. It has not happened to me but I need it for some research I'm doing. Thanks. Answered by Krystin Chuyangher 1 year ago.

The type of medicine is Adrucil. My scenario is that someone is trying to inject the patient and sticks it in their finger by accident. This has not happened to me or anyone I know, I was just curious. I just need to know what a doctor would do, the side affects, or if it would do anything at all. Thank you for your answers. Answered by Beatris Trennell 1 year ago.

What if??? Your average doctor doesn't even have such medication on hand to "accidentally" inject you with. Your scenario is so far out of normal practice is it inconceivable. Your doctor doesn't have a $2,000 bottle of Oncovin just laying around his/her office just in case the stray cancer patient that might need Oncovin to treat their disease. Most doctors would not even administer or have such a drug, unless they were Oncologist working in a hospital setting. Answered by Larita Kelson 1 year ago.

You're going to have to be a lot more specific than this. If you're doing research, then you should know that you can't ask an incredibly vague question like this and receive any type of reliable or accurate answer. Your only shot at getting a remotely valid response is if you provide the exact medication in which you are asking about. You should know that all medications have different effects, risks, etc. And even if you do provide the specific name, it doesn't mean you'll get a correct answer. Different things affect different drug side effects, and different people react differently to every drug that exists. For example, if you eat grapefruit while taking xanax, you can intensify the effect of xanax, which could be fatal for some. If you have been taking certain types of pain medication and you take Suboxone or Subutex, you will be thrown into severe withdrawal and could die. Some drugs have completely different effects based upon whether they are taken orally or injected. If you inject suboxone or subutex, you will be thrown into severe withdrawal, period. If you take it orally, under the tongue, as prescribed, the medication will act as it was intended. Some people die the very first time they try ecstacy, while others do not. Some people are allergic to penecillin. Others are not. Certain drugs have off-label uses. For example, certain psychotic drugs, such as schizophrenia medications are prescribed to mentally sound people to help them focus. If you do not have schizophrenia and take this medication, you will have incredible focus and attentiveness. Another example is ADD/ADHD medication, such as Adderall. If someone with ADD takes it, they are calmed down, and are able to focus. If someone without ADD takes it, it has the opposite effect... it's similar to the affects of "speed" and gives them endless energy and drive. Lastly, how in the world would someone be accidentally injected with anything? That is nonsensical. This whole question is nonsensical. This is a very poor question, and I fear for those who may receive the outcome of your "research" ... Answered by Ashanti Bruski 1 year ago.

This is a very vague question. If you were accidentally injected with a chemotherapy agent it would depend on which one it was, some of them cause severe tissue necrosis if they are not diluted and injected slowly into a "good" vein. There are some agents that can neutralize chemo agents, and there are some drugs that can reverse the side effects of other drugs. But for the most part if you were injected with something it's not comming out of you that is impossible, you just must deal with the side effects of that drug until it clears you system. Answered by Hye Terrasi 1 year ago.

(1) Main GOAL of CANCER drugs: to STOP CELL DIVISION in cancerous cells. (2) Whether one has cancer or not, cancer drugs will affect normal cells as well like the ones of your hair. Answered by Hung Houseworth 1 year ago.

Nothing, unless you have an aleragic reaction to it. Then they would give you Benadryll. I am not a Dr. this is just my guess. Answered by Betsey Cayton 1 year ago.


What does fluorouracil cream do?
My podiatrist prescribed fluorouracil cream after treating plantar warts. Asked by Darcie Courtney 1 year ago.

What is the most important information I should know about fluorouracil topical? Do not use fluorouracil topical on skin that is irritated, peeling, or infected or on open wounds. Wait until these conditions have fully healed before using fluorouracil topical. Fluorouracil topical is in the FDA pregnancy category X. This means that it is known to harm an unborn baby. Miscarriage and birth defects have been reported when fluorouracil topical was applied to mucous membrane areas by pregnant women. Do not use fluorouracil topical if you are pregnant or planning a pregnancy. Discuss with your doctor appropriate forms of birth control before starting treatment with fluorouracil topical. Fluorouracil topical is available in a number of strengths and forms (creams and solutions). It is very important that you use the correct form and strength. Contact your doctor or pharmacist if you have questions regarding which product to use. Avoid exposure to sunlight or artificial UV rays (e.g., sun lamps) during and immediately following treatment with fluorouracil topical. Use a sunscreen with a minimum sun protection factor (SPF) 15 and wear protective clothing when sun exposure is unavoidable. Individuals with fair skin may require a sunscreen with a higher SPF rating. (back to top) What is fluorouracil topical? Fluorouracil interferes with the growth of skin cells. Fluorouracil works by causing the death of cells which are growing fastest, such as abnormal skin cells. Fluorouracil topical is used to treat scaly overgrowths of skin (actinic or solar keratoses). Fluorouracil topical may also be used in the treatment of superficial basal cell carcinoma. Fluorouracil topical may also be used for purposes other than those listed in this medication guide. (back to top) What should I discuss with my healthcare provider before using fluorouracil topical? Before using fluorouracil topical, tell your doctor if you: have ever had an allergic reaction to another form of fluorouracil topical (Carac, Efudex, Fluoroplex) or injectable fluorouracil (Adrucil, 5-FU); or have dihydropyrimidine dehydrogenase (DPD) enzyme deficiency. You may not be able to use fluorouracil topical, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. Fluorouracil topical is in the FDA pregnancy category X. This means that it is known to harm an unborn baby. Miscarriage and birth defects have been reported when fluorouracil topical was applied to mucous membrane areas by pregnant women. Do not use fluorouracil topical if you are pregnant or planning a pregnancy. Discuss with your doctor appropriate forms of birth control before starting treatment with fluorouracil topical. It is not known whether fluorouracil topical passes into breast milk. Do not use fluorouracil topical without first talking to your doctor if you are breast-feeding a baby. The safety and effectiveness of fluorouracil topical in patients younger than 18 years of age have not been established. (back to top) How should I use fluorouracil topical? Use fluorouracil topical exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Fluorouracil topical is available in a number of strengths and forms (creams and solutions). It is very important that you use the correct form and strength. Contact your doctor or pharmacist if you have questions regarding which product to use. Clean the area where you will apply fluorouracil topical. Rinse well and dry the area with a towel and wait ten minutes before applying the medication. Wash your hands before and immediately after applying this medication, unless it is being used to treat a hand condition. Apply fluorouracil topical to the affected area with the finger tips or a non-metal applicator, smoothing it gently onto the affected skin. Use enough to cover the entire area with a thin film. Fluorouracil topical should not be applied on the eyelids or in the eyes, nose, or mouth. Use caution when applying fluorouracil topical around the eyes, nose, or mouth. Do not use fluorouracil topical on skin that is irritated, peeling, or infected or on open wounds. Wait until these conditions have fully healed before using fluorouracil topical. Do not cover the area after applying fluorouracil topical. This could cause too much medicine to be absorbed by the body and could be harmful. If a covering is needed, ask your doctor if a porous gauze dressing may be used. A moisturizer or sun screen may be applied 2 hours after fluorouracil topical has been applied. Do not use any other skin products including creams, lotions, medications, or cosmetics unless instructed by your doctor. The reaction of the skin treated with fluorouracil topical may be unsightly during treatment, and sometimes, for several weeks after completion of therapy. Store fluorouracil topical at room temperature away from moisture and heat. (back to top) What happens if I miss a dose? Apply the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and apply only the next regularly scheduled dose. Do not apply a double dose of this medication. (back to top) What happens if I overdose? An overdose of fluorouracil topical is unlikely to occur. If you do suspect an overdose, or if fluorouracil topical has been ingested, call a poison control center or an emergency room for advice. (back to top) What should I avoid while using fluorouracil topical? Do not use other prescription or over-the-counter skin products without first talking to your doctor during treatment with fluorouracil topical. They may interfere with the treatment or increase irritation of the skin. Avoid exposure to sunlight or artificial UV rays (e.g., sun lamps) during and immediately following treatment with fluorouracil topical. Use a sunscreen with a minimum sun protection factor (SPF) 15 and wear protective clothing when sun exposure is unavoidable. Individuals with fair skin may require a sunscreen with a higher SPF rating. (back to top) What are the possible side effects of fluorouracil topical? Serious side effects are not likely to occur. Stop using fluorouracil topical and seek emergency medical attention if you experience an allergic reaction (shortness of breath; closing of your throat; swelling of your lips, face, or tongue; or hives). Fluorouracil topical may cause skin irritation, dryness, scaling or peeling (exfoliation), rash, and other local reactions. Eye irritation has also been reported. If these side effects are excessive or worsen with continued treatment, contact your doctor. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. (back to top) What other drugs will affect fluorouracil topical? Do not use other prescription or over-the-counter skin products without first talking to your doctor during treatment with fluorouracil topical. They may interfere with treatment or increase irritation to the skin. Drugs other than those listed here may also interact with fluorouracil topical. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines. (back to top) Where can I get more information? Your pharmacist has additional information about fluorouracil topical written for health professionals that you may read. (back to top) What does my medication look like? Fluorouracil topical is available as a cream or topical solution with a prescription under the brand names Fluoroplex, Efudex and Carac. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you. Carac 0.5%--cream Fluoroplex 1%--cream Fluoroplex 1%--topical solution Efudex 2%--topical solution Efudex 5%--topical solution Efudex 5%--cream (back to top) Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Answered by Clementine Riesenweber 1 year ago.

Fluorouracil Cream Usp 5 Answered by Lorean Mccrady 1 year ago.

This Site Might Help You. RE: What does fluorouracil cream do? My podiatrist prescribed fluorouracil cream after treating plantar warts. Answered by Claris Brancanto 1 year ago.


How do drugs halt mitosis?
Maligant tumors are sometimes treated with drugs that halt mitosis, and thus stop the production of new cancer cells. two such drugs, vincristine sulfate and vinblastine sulfate, interfere with the formation of spindle fibers. how could this action halt mitosis?Some drugs can also interfere with DNA... Asked by Larry Ohl 1 year ago.

Maligant tumors are sometimes treated with drugs that halt mitosis, and thus stop the production of new cancer cells. two such drugs, vincristine sulfate and vinblastine sulfate, interfere with the formation of spindle fibers. how could this action halt mitosis? Some drugs can also interfere with DNA synthesis in treated cells. How could this action halt mitosis? Answered by Lucinda Pysher 1 year ago.

Catagories of Chemotherapy Drugs: In general, chemotherapy agents can be divided into three main categories based on their mechanism of action. Stop the synthesis of pre DNA molecule building blocks: These agents work in a number of different ways. DNA building blocks are folic acid, heterocyclic bases, and nucleotides, which are made naturally within cells. All of these agents work to block some step in the formation of nucleotides or deoxyribonucleotides (necessary for making DNA). When these steps are blocked, the nucleotides, which arethe building blocks of DNA and RNA, can not be synthesized. Thus the cells can not replicate because they cannot make DNA without the nucleotides. Examples of drugs in this class include 1) methotrexate (Abitrexate®),2) fluorouracil (Adrucil®), 3) hydroxyurea (Hydrea®), and 4) mercaptopurine (Purinethol®). Directly damage the DNA in the nucleus of the cell: These agents chemically damage DNA and RNA. They disrupt replication of the DNA and either totally halt replication or cause the manufacture of nonsense DNA or RNA (i.e. the new DNA or RNA does not code for anything useful). Examples of drugs in this class include cisplatin (Platinol®) and 7) antibiotics - daunorubicin (Cerubidine®), doxorubicin (Adriamycin®), and etoposide (VePesid®). Effect the synthesis or breakdown of the mitotic spindles: Mitotic spindles serve as molecular railroads with "North and South Poles" in the cell when a cell starts to divide itself into two new cells. These spindles are very important because they help to split the newly copied DNA such that a copy goes to each of the two new cells during cell division. These drugs disrupt the formation of these spindles and therefore interrupt cell division. Examples of drugs in this class of 8) miotic disrupters include: Vinblastine (Velban®), Vincristine (Oncovin®) and Pacitaxel (Taxol®). Answered by Maria Scantlin 1 year ago.

Drugs that interfere with the normal progression of mitosis belong to the most successful chemotherapeutic compounds currently used for anti-cancer treatment. Classically, these drugs are represented by microtubule binding drugs that inhibit the function of the mitotic spindle in order to halt the cell cycle in mitosis and to induce apoptosis in tumor cells. However, these compounds act not only on proliferating tumor cells, but exhibit significant side effects on non-proliferating cells including neurons that are highly dependent on intracellular transport processes mediated by microtubules. Therefore, there is a particular interest in developing novel anti-mitotic drugs that target non-microtubule structures. In fact, recently several novel drugs that target mitotic kinesins or the Aurora and polo-like kinases have been developed and are currently tested in clinical trials. In addition, approaches of cell cycle checkpoint abrogation during mitosis and at the G2/M transition inducing mitosis-associated tumor cell death are promising new strategies for anti-cancer therapy. It is expected that this "next generation" of anti-mitotic drugs will be as successful as the classical anti-microtubule drugs, while avoiding some of the adverse side effect Answered by Rosena Conoly 1 year ago.

spindle fibers are used to move the chromosome and orgenelles to opposite sides if you cant dupliccate DNA then you cannot spilt a chromosome for the daughter cells Answered by Angle Maroni 1 year ago.


5 days after first chemo treatment?
A friend of mine was diagnosed with colon cancer. He recently went through his first chemo treatment, but it has only been five days after and has already lost all his hair both atop his head and beard. I am concerned because my mother in the past had chemo and her hair did not fall out nearly as quick, it took... Asked by Francisco Ginnetti 1 year ago.

A friend of mine was diagnosed with colon cancer. He recently went through his first chemo treatment, but it has only been five days after and has already lost all his hair both atop his head and beard. I am concerned because my mother in the past had chemo and her hair did not fall out nearly as quick, it took weeks and it took more than one treatment. Is it possible they are using something stronger than chemo and if so, what questions should he ask his doctors to get the proper answers? It really makes me worried. I know everyone's bodies react differently. But I feel as if five days after is extreme for someone to become fully bald and only after one/first treatment of chemo therapy. Answered by Stephanie Cowher 1 year ago.

My sons both became bald from shear stress after their father died. Now my oldest son is 42 and has gone thru 7 rounds of chemo and lost his beard but the doc said the radiation treatments he is facing next will cause the rest to fall out. Every med they use in chemo reacts diff.he has stage 4 head and neck cancer. Answered by Suzan Guynup 1 year ago.

Everyone is different. I woke up with a full head of hair day 10 aftter my first treatment and was bald before I went to bed that night. Answered by Odis Wainkrantz 1 year ago.

Everyone could have a different reaction. Hair could fall out, thin, stay normal. My onco was sure I would lose mine and I didn't lose any to chemo. Doesn't mean it's working any more or less. Poppy, 2 months ago, you said your son was done with chemo and starting radiation....and apparently your son is in chinese prison for drug trafficking, making Ralph Lauren products lol that makes you less than believable. Answered by Valorie Bundick 1 year ago.


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