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Questions, experiences and reviews (16)

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Does anyone have any experience with the medication spironolactone?
Does spironolactone cure acne? Does it help with female hairloss? Any information will help. I also would like to know about side effects and if it could potentially harm me.
  Yes, I've used Spironolactone on many of my patients interested in helping with their acne. It's true, it is a diuretic (water pill) usually intented for those with high blood pressure, but it also has other indications, acne prevention for example.

I couldn't tell you exactly how it works, but I know that Spironolactone blocks adrogen production, a hormone that is very much involved with acne production and hair growth. I'm not going to search the web and cut and paste an explanation, I'm just going to tell you from my own medical experience that I have prescribed it for treatment of hair loss and acne.

Since it is a water pill, the usual side effects are water loss (you'll urinate more frequently), increased potassium levels (although rare, it's potentially the most dangerous one), and kidney problems. If you're female, I warn my patients that it will probably cause menstrual irregularities and occasional breast tenderness, but those symptoms will probably fade away.

My recommendation is to see your primary care doctor and see if he/she can manage it, check your blood work, etc. If not, then see if your doctor can refer you to a dermatologist. Good luck.
Tyler PA
what danger is there in taking Spironolactone,Amlodipine and Metroprolol?
50mg Spironolactone,200 mg Metoprolol ,10mg Amlodipine. all this once a day and i just dont feel right.
spironolactone and penicillin
Hi i've been on spironolactone for about 6 months and now i'm sick and on penicillin 2 pills 2 times a day for 10 days is mixing this medication safe?
Is it ok to take Spironolactone and potassium supplements?
I don't food rich in potassium, so I start supplementing with 2 supplements per day which provide a total of 6% of my daily value. I also take spironolactone 25mg once a this safe? I know that drug causes potassium to stay in the body. Since I started this new drug last week, I've been very sleepy.
Lifes a beach
  Spironolactone often increases serum potassium levels and can cause hyperkalemia, a very serious condition. Therefore, it is recommended that people using this drug avoid potassium supplements and salt substitutes containing potassium. Doctors usually recommend periodic screening of serum potassium levels and some patients may be advised to limit dietary consumption of potassium.

Do not use spironolactone if you have kidney disease, urination problems, or high levels of potassium in your blood. Do not use salt substitutes or low-sodium milk products that contain potassium. These products could cause your potassium levels to get too high while you are taking spironolactone.

If you are taking potassium supplements or other potassium-sparing diuretics such as Aldactazide, amiloride (Midamor, Moduretic), or triamterene (Dyrenium, Dyazide, Maxzide).

Check with your doctor regarding your sleepy symptom if this continues. Are you taking this for high blood pressure? Chronic Fatigue Syndrome is caused by low potassium. So, your doctor needs to evaluate your potassium levels as this could be causing your fatigue.

Hope this helps.
syl c.
On spironolactone (diuretic). How much water should I drink to stay hydrated?
I'm currently on a diuretic called spironolactone for pcos symptoms, and I think I'm experiencing mild dehydration (sunken eyes, pale flabby skin, dizziness). I'm trying to drink as much water as possible. It just seems like it's not enough though. How much water should I be drinking, and is there anything else I can do for my body to stay hydrated?
  If you are mildly dehydrated, you need to drink enough liquid to replace the fluids you have lost. Also, you need to replace the electrolytes you have lost. Drinking sips of water slowly, along with eating the typical American diet, which is high in salt, will replace fluids and salts you have lost. You should see a health care provider if you are feeling confused, dizzy, or faint or if you have persistent nausea or vomiting.

You can replace fluids and electrolytes by drinking sports drinks or other oral rehydration solutions (ORS). Drink the solution right away. Do not wait until dehydration becomes severe.

Packets of oral rehydration salts are widely available. Mix the contents of a packet with 1 quart or liter of drinking water. If you are not sure if the water is safe to drink, first boil the water for at least 5 minutes.

If you don't have a sports drink or ORS packet, you can make an oral rehydration solution using the following recipe: To 1 quart or liter of drinking water or boiled water, add the following:

2 tablespoons sugar
1/4 teaspoon salt
1/4 teaspoon baking soda (bicarbonate of soda).
If you don't have any baking soda, add another 1/4 teaspoon of salt. If possible, add 1/2 cup orange juice or some mashed banana to improve the taste and provide some potassium.

Drink sips of the ORS every 5 minutes until urination becomes normal. (It's normal to urinate 4 or 5 times a day.) Adults and large children should drink at least 3 quarts or liters of ORS a day until they are well.

Good Luck!
  Don't add the potassium - spironolactone is a potassium sparing diuretic and adding potassium can cause levels to rise in the blood which can eventually become life threatening.
I'm a 26 year old female with facial hair. Will Vaniqa cream or Spironolactone help??? Any other ideas???
I've got fair skin and fair hair, so electrolysis is not an option. I really don't want to have to wax/shave my face. Has anyone tried Vaniqa cream? If so, do you know if it can be used in combination with Retin-A cream (I use that for acne). Also, has anyone tried Spironolactone (Aldactone)? Any other ideas for me??? Thank you so much for your help!
  i have the same thing ur talking about and my obgyn said that i have (PCOS) u can look that up on google ... and i'm only 22 so u might want to look it up and then ask ur doctor about it or something .....
Jessica C
Can a person who takes synthroid also take spironolactone and metformin?
I have hypthyroidism and i'm taking synthroid, but my doctor also gave me spironolactone and metformin to take also. I've been getting stomach aches and i feel dizzy most of the time after taking my medication. do i have a high dosage? i told my doctor but he said to give my body awhile to adjust. what should i do? is there a time frame that i should take my meds without making me feel bad after takin it?
how long do i have to take Spironolactone before i see any benefits in excess body hair?
i am taking Spironolactone for my Hirsutism
i also have PCOS

how long will i see the benefits and a reduced amount of excess, and how long will it be until it disappears forever?
and if i stop taking it will my hair come back?

i am taking a 50mg pill once a day.
  I'd say you need a long time, also, the hair will grow back. FYI, do you know that taking too much can precipitate a heart attack? Would you rather have excess hair or die with excess hair?
Doctor Gaga
What are the effects of spironolactone on acne? Also,if I get 2 much potassium from this drug,what can happen?
I am wondering about the drug Spironolactone and it's effects on people taking it for acne. Since this drug dramatically increases potassium in the bloodstream, what the the effects if a person takes too much potassium? Are their side effects? I thought potassium was a good thing, but I hear now that too much can kill you?
  Excessive potassium can cause a heart arrythmia (irregular rhythm). When taking any drug that can alter electrolyte balance, periodic blood work needs to be done.
Ramona H
I am currently experiencing sever leg cramps, is aldactone (spironolactone) causing this?
I currently am taking aldactone (spironolactone) I was wondering if anyone knew of this causing muscle cramps. Due to this medication being potassium sparing; i wasnt sure if maybe i am having muscle cramps (mostly in legs) due to this medication or an overdose of potassium due to my dosage of 200mg a day. Thanks for your help.....
In deep thought?
  I could be. The cramps in the legs could be caused by blood clots. I would have a doctor use a dopler on your leg to see if there is a normal flow of blood getting through your legs. The dopler does not require any surgery.
Ya Buddy!!!
Hirsutism-How long will I have to take spironolactone and at what dose before i notice my facial hair fading?
I have alot of dark coarse chin hairs. I have read alot about spironolactone helping alot with getting this under control. But at what dose, and for how long until I would start to notice a difference? also, does it lower blood pressure a whole lot? I naturally have low blood pressure so I hope it will be ok for me to take for hirsutism. thanks
  Get a blood pressure check after a month on Spironolactone. You can get it tested at many pharmacies. A month should make a difference in the texture of the hairs, took, as it will have reduced your androgens.
Susan S
will Estraderm and Spironolactone show up in a urinalysis?
  Not if a routine urinalysis test is done - or even a drug screen. I do urine testing almost every day and I've never seen these. Now, if a doctor orders a special send out test to look for these things and the samples get sent to a special reference lab then maybe.
Is anyone here on Spironolactone or Flutamide and why?
Why did a DR. Prescribe, Did it work, Did it have bad side effects? Thanks so much.
  I am not on the med spironolactone, but my Mom is. She has Conjestive Heart Failure, is really bad to collect fluid around her heart and lungs as well. She has had no bad side effects, and yes it does help. She also takes lasix with this. She also has COPD. Drink water, but watch your fluid intake. Don't overtake, you can dehydrate. And, keep a check on your potassium levels.
How many Mg do you take of spironolactone?
Why do some doctors say to take 200mg and others say 100mg. Is is based on wieght. I am not looking for medical advice, just curious...
Whats the standard for hirsutism?
  This drug isn't considered a very strong diuretic, though many doctors when first perscibing any new drug try and prescribe the lowest dose, in the case of this drug lowest milligram, and bulid from there. It also depends on the severity of the edma or hyperkalemia, which ever it was perscribed for. The milligram dosage for spironlactone are 25, 50, 100mg.

I have a medical question. Why would a man be taking estradiol along with spironolactone?
I have a coworker who is seeing a therapist and has recently been put on those medications. Says most of his friends have gone due to not understanding his issues and that he has not told his parents due to they would not understand either. I do know that estradiol is a female hormone so I guess Im wandering if these are something taken for sex changes, men wanting to be women?
Amanda C
  A MAN wouldn't be taking oestradiol and spironolactone ; but a transsexual woman would.
Both drugs are often prescribed to transsexual women; oestradiol for it's feminising effects, and spironolactone for it's androgen-blocking effects.

Oestradiol is sometimes prescribed for prostate cancer, and spironolactone is sometimes prescribed for hypertension, but they wouldn't be prescribed together; oestradiol RAISES blood pressure, so they would cancel one another out.
Does anyone know a natural alternative to spironolactone for pcos?
I have elevated androgens, acne, mild hair loss, excess body hair. My weight is perfect though. I also have mild hypoglycemia due to insulin issues.

I HATE DRUGS. Has anyone found an alternative to spiro? One of my holistic docs (the endocrinolist one) is suggesting spiro and metformin.

Yes, drugs have plants in them. But they also have toxic man made ingredients.
  You are very, very wise to try to avoid pharmaceutical drugs if at all possible. Yes, there are alternatives to spironolactone and metformin in the treatment of PCOS. Natural treatment of polycystic ovarian syndrome is multifactorial. You should see a qualified naturopath for specific herbal remedies and diet recommendations, but the basics are below.

Lifestyle. Exercise and weight reduction have been shown to be highly beneficial in the treatment of PCOS and its symptoms. Exercise can helps reduce weight, regulate menstrual cycles, and reduce risk factors for diabetes and heart disease which are associated with PCOS.

PCOS Diet. Women with PCOS respond well to a low glycemic index, low simple carbohydrate, low animal product, high fiber diet which helps reduce weight, regulate blood sugar and insulin levels, and reduce inflammatory prostaglandins.

Nutritional Therapy. Depending on your specific presentation of PCOS, there are a variety of nutritional therapies which will be considered. Nutritional therapies can help to regulate blood sugar and insulin levels, reduce circulating androgens, improve ovarian function, improve fertility, reduce risk of heart disease, and support liver detoxification of estrogens.

Herbal Therapy. Depending on your symptoms of PCOS, a variety of herbal therapies may be considered. The goal of herbal medicine might include: reducing circulating androgens, optimizing ovarian function, and supporting optimal endocrine function.

By the way, just to let you know why you are so wise to avoid spirolactone: Even though the drug that your endicrinoligist is suggesting has been shown to be effective in hormone-induced acne it has various unpleasant side effects. Spironolactone is a diuretic [it causes you to pee a lot]. The side effects in low-dose spirolactone are:

irregular menstrual cycle [most common]
breast tenderness [most common]
thirst, dry mouth
stomach cramps, vomiting, and/or diarrhea
increased blood potassium levels
low blood pressure

Both blood potassium levels and blood pressure should be checked periodically while you're taking this medication. Also, you shouldn't get pregnant while using spironolactone. And spironolactone isn't a good choice for you if you have kidney problems, or a history (or family history) of breast cancer, uterine cancer, or ovarian cancer. According to the National Institutes of Health, spironolactone is known to have caused tumors in lab animals.

Metformin is also much less desirable than the low Glycemic Index diet that is recommended for PCOS patients. Its side effects include:

MULTIPLE MEDICATIONS. You may be at risk for health problems or symptoms if you take metformin in addition to other medications.


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