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Have you ever heard of someone abusing the drug Promethazine? I was wondering if it has side effects, as I think someone might have jacked my prescription. I got it for a surgery to help with nausea, and I was wondering why anybody would have a reason for stealing PROMETHAZINE?
  One reason would be for the anti nausea it gives so if you were hungover. Promethazine is sometimes used as a recreational drug in conjunction with codeine in prescription cough syrup. The syrup by itself contains 7% alcohol. The mixture of Sprite and cough syrup with codeine, which is known as "purple drank" or "Sizzurp", is popularized in the rap world, especially in the Houston area.
What is the difference between promethazine with codein and promethazine with dextromorphan?
Will it kill me? We have the promethazine with dextromorphan will this still work for purple lean?
Bob B
  Dextromethorphan is a cough suppressant that is found in many over-the-counter cough medicines. Codine is a narcotic that is used as cough suppressant, pain reliever, and a hypnotic.

Promethazine is used mostly to prevent nausea. It is also used as part of preoperative sedation to prevent nausea from the other types of sedation used.

If you have both, I don't recommend using them BOTH at the same time. You may overdose.
What is the difference between Promethazine VC w/ Codeine and Promethazine w/ Codeine?
I get pneumonia frequently and they usually give me Promethazine w/ Codeine 10-6.25 for my cough. This time they prescribed Promethazine VC w/ Codeine 10-5-6.25 instead. What is the difference and what does the "VC" mean?
Fireman 1
  VC stands for the addition of a decongestant- so you have promethazine which is an antihistamine and codeine an opiod all in one. Sounds like it may work for you. Be careful with driving until you get used to their effect. It may also affect your sleep patterns.
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What can I tell my doctor to get Promethazine prescription?
I get it illegally but I'm getting too nervous about it, just help a brother out. I'm thinking that if I tell him that I get motion sickness when driving and that someone reccomended Promethazine it should work.
  You can get it over the counter in the United Kingdom, Switzerland, and many other countries (brand names Phenergan, Promethegan, Romergan, Fargan, Farganesse, Prothiazine, Avomine, Atosil, RhinathioL) So I would try to order it from one of the companies over there in bulk.

It's also used as an antihistamine (like Bennedryl). It blocks the effects of histamine in your body.

Promethazine treats allergy symptoms such as itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes. It also prevents motion sickness, and treats nausea and vomiting or pain after surgery and is used as a sedative or sleep aid. (Taken off the pamphlet that comes with a prescription)

So I would go with really bad allergies that keep you awake all night.

PS they wont give you a prescription if you have high blood pressure.

purple drank <3 haha
Whats the difference between Promethazine w/codeine and Promethazine DM? What does DM mean?
  One has codeine and the other has dextromethrophen in it. They are both cough suppressents.
Roberta P
Does Promethazine or Codeine have any traces of cocaine in it?
Some dumbass white dude at my skool keeps trying to say Purple Drank/Purple Lean has cocaine in it. I'm tellin him that all Purple Drank is Sprite, and Promethazine/Codeine Cough Syrup. So basically the question is: does Promethazine or Codeine have any cocaine? I know Codeine is a narcotic, made from opium, so I dont think it has any cocaine in it.
  No. Cocaine is stimulant, and a completely different compound extracted from coca leaves. Codeine is an opiate, synthesized from morphine which in turn is synthesized from opium. Cocaine would definitely not be in a codeine mixture.
Does all promethazine have codine in it my bottle just says promethazine dm?
I have a bottle of promethazine dm but it doesent say if it contains codine or not
if not than what can i do to it to get high?
  No narcotics.

Be realistic. No medical professional is going to help you do something dumb like abuse Rx drugs.
I was about to take come promethazine but it says it expired about 5 1/2 months ago.....So my question is is it safe to take it even though it expired?

Wouldnt it just make potency less?
Dj R
  Don't take medicine past the expiration.

In some cases old meds become less potent but some can become more potent - which can easily lead to an overdose.
Is it okay to mix Promethazine and Profen II DM?
I take Promethazine for stomach aches and i have been having tough issues with my coughing, so is it okay to mix the two? also Ive heard a lot about cough medicine abuse, are the two going to mess me up?

I took adderall xr 30mg this morning but im sure it wont affect the medicine, will it?
Zach F
Question for someone whos been prescribed promethazine with codeine syrp recently?
I was always curious about promethazine with codeine syrup and i wanted to know what dosage it says on the bottle... Does it just say how to take it or the name, or does it show dosage wise! Just wonderin, thanks!
  the dosage is usually determined by a doc, & depending on his/her directions, it will say how to take it. It really works to get rid of a bad/resistant cough & a good night's sleep.
Is it safe to use promethazine with an epipen?
I had my wisdom teeth removed on Friday and was prescribed promethazine for nausea. Today, after taking that, my dust allergy acted up and I took benadryl along with my epipen. Is this safe? I didn't see any warnings on either medication. Thanks for any help.
nyx コト
  It should be fine.

Why did you use the epipen? That's for life threatening allergic reactions. I've never seen a dust allergy that was life threatening.
with a really bad cough is there somewhere i can get promethazine with codeine w/o prescription?
where can i find promethazine w codeine plz help me out
  not without a prescription
What would the combination of Promethazine and Ambien do, if taken in fairly large amounds and same time?
I'm just curious what would ambien and promethazine do if taken at the same time?
Curious Cutie
  That sounds like a poor man's "Purple Drank". Using a sleeping pill instead of codeine in the drug you're trying to emulate will drastically increase the risk of respiratory failure. The original is dangerous enough. What you just mentioned is even worse. If you go too far over the recommended medicinal dose you run a very high risk of passing out and your lungs shutting down.

The increased risk comes from the fact that both Promethazine and Ambien can stop your breathing at high doses. You'd be taking two drugs that, individually, could kill at a high dose.

All these drugs show up on a standard toxicology screen.
Lean, Promethazine, Codeine, Sizzurp... Heeelp?
What are the effects of Promethazine/codeine? Is there any bad side effects or any bad reactions you can get from it? I've had a bad past with weed, & have major panick attacks that last a while whenever i do smoke. So i completely quit. Alcohol doesnt have any bad effects on me. But i wanna try leaning, Anybody have any bad experiences ? Do you think i'll panic from it ?
Would taking Paxil, Morphine, and promethazine with codeine all at the same time kill?
I need to know right away, if there deadly or not. I just took all three together:
120mg of Morphine
About 5 Table Spoons of Promethazine w/Codeine
& 40mg of Paxil
Possible overdose on Promethazine and Codeine cough syrup?
I got confused and took 2 Tablespoons of Promethazine with Codeine cough syrup instead of 2 teaspoons do i need to call poison control or will i be okay?
  You'll be fine. You might feel a little high though. Just lay down, drink lots of water.
Sex Addict
can i get high off promethazine hydrochloride 25 mg?
can i get high off promethazine hydrochloride 25 mg? pill white and round with GG 225
wooop, there it is!
  Sure, just take 19 of them, they'll make you pickle!
can you take Meloxicam with Promethazine w/ Codeine?
i was at the doctors Wednesday with just a sore throat. nothing major. so i got prescribed Meloxicam to reduce the swelling. The day after worse symptoms started kicking in. Just went back to the doctors today and he prescribed me the Z-pack and Promethazine w/ Codeine. I forgot to ask if i could take the Meloxicam with that, so can i?
Tyler Bryant
How many promethazine should I take with one oxycodone?
I just got my wisdom teeth pulled out and my docter perscribed me oxycodone to relieve the pain and promethazine to relieve any sickness I would feel from the pain reliver. I am scared to take the the oxycodone cause im scared of being nauses!
Caleb Mcneal
  Oxycodone for a pulled wisdom tooth? I hope you don't get addicted to it. If a doctor prescribed the medicines for you, then the prescribed directions for both drugs should be listed on the bottles.
side effects of promethazine hydrochloride pills?
my insomnia has worsened lately so my doctor gave me some promethazine hydrochloride 25mg pills. I'm 14 years old and I just wanted to ask whether anyone of you had taken these pills before and whether you can tell me some of its side effects.
  I find some information about Promethazine at
There is description of side effects, dosage, using of this medicine. Hope it will be useful.
Tramadol, Flexeril and Promethazine the risk of seizure can I take?
I've taken 3 tramadol earlier today last one around 6pm. It made my stomach hurt so I took a promethazine around 10pm. Now, the pain is back and I want to sleep is it safe to take my flexeril? I don't have a history of seizures but when I check the interaction it says theres a risk for seizures. My pharmacist says that's only if you've had history of seizures who do I believe?
Count Drakul
  i take Tramadol daily and I have taken Promethazine with it. It may increase the effects of tramadol and the drug interactions site does say it may cause seizures but i think that is very rare. You usually have to have a history of seizures for this to happen usually. It is also associated with large doses of Tramadol, 300mg and up. The Flexeril should be fine too. 9 times out of 10 the pharmacy wont tell you to do anything dangerous but sometimes the drug interaction checker will scare you. It's always good to be cautious though, you don't want to be another Heath Ledger.
Deep Thinker
what is the difference between promethazine vc syrup and promethazine dm syrup?
Maria P
  promethazine vc does NOT contain codeine unless its says promethazine vc with codeine.

prom-vc is an antihistamine and decongestant

prom-dm is is an antihistamine and cough suppressant
How much Promethazine is "safe" to take if you weigh 110 pounds?
I weigh 110 pounds and need to take Promethazine because of allergies. How much is safe and how much does it take to overdose?
  To be perfectly blunt, it's however much your doctor prescribes to you. Any prescription will be given based on your need which can involve factors more than just weight, age, and gender and some drugs require blood work to find the appropriate dosage. Online, we would have no access to the basic information that would be required to say what dosage you would need... but moreso, only your doctor can prescribe your needed dose so whatever dose anyone here might say is moot if your doctor won't prescribe that dose for you. points out that it's simply an antihistamine (which also can help with motion sickness)... it's not really a drug you can abuse so the highest "safe" dose would also be a moot point. The answer would be to ask your doctor how much you should be taking. Good luck and I hope I helped!
Where in the world can you buy Promethazine w/ Codeine Syrup without a prescription?
Where in the world can you buy Promethazine w/ Codeine Syrup without a prescription? I thought that you could in Canada but I'm not sure now, any ideas? Thanks.
Promethazine & Solodyn (Stomach Ache)?
My stomach has been hurting for the past hour or so feeling as if I may be vomit at some point later. I'm 16 and I take a pill of Solodyn and Claritin every night for Acne and Allergies. (Solodyn is prescribed) I had also taken a Loperamide Hydrochloride for constipation and diarrhea symptoms at about 12:30am EST (The other 2 pills at about 10pm EST. If I use a Promethazine (prescribed for stomach aches after my nasal septum surgery) suppository for this stomach ache now will it affect me negatively with having taken the other meds?
Any questions ill edit the post and answer my best. Thanks for any help in advance.
Steve G

Only use the promethazine if you are nauseated or vomiting. It won't do a thing for a stomachache.
John M
how do i get a prescription for promethazine with codeine cough syrup?
i want to know what EXACTLY to say to my doctor to get promethazine with codeine cough syrup..and u think she could tell if i need it wen she looks at my throat?? well just tell me EXACTLY wat i need to say to get the prescription. thanks
  Why do you want this? Is it because you have a terrible cough or because you want the codein? Tell him/her the problem and the doctor will decide what you need. I'm guessing the doctor will NOT give you promethazine because that is for NAUSEA.
Anne D
What is the diffrence between Promethazine w/Codeine and Tussionex?
dose any one know the diffrence between Promethazine w/Codeine and Tussionex.....
  Tussionex is hydrocodone polistirex and chlorpheniramine polistirex. so it is the same type of thing a cough suppressant/pain killer and an antihistamine.
what is the diffrence between Promethazine w/Codeine and Tussionex?
dose any one know the diffrence between Promethazine w/Codeine and Tussionex.....
  promethazine + codeine= promethazine w/ codeine
Can yellow promethazine DM cough syrup be used for sizzurp?
Don't tell me I'm making a bad choice. This site is for answering people's questions. Purple Drank" or "Sizzurp" is cough syrup mixed with Sprite and jolly ranchers, getting you high. Can the yellow cough syrup containing promethazine get you high like the original purple drank?
And how much of the cough syrup should I pour in my cup?
Geo Villacorta
  yeah you are making a bad choice. sizzurp is hella bad. try salvia or weed.
Promethazine can it be used to treat nerves or mental problems?
Promethazine can it be used to treat nerves or mental problems? What is is normally prescribed for?
  Promethazine is an antihistamine medication. It's used to treat allergies, or rarely as a short term sleep aid. It has no use at all for any sort of mental illness or anxiety.
Az R

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